New study finds a modest increase in depression treatment rates, but non-financial barriers persist. Medicaid expenditures for mental health conditions have increased significantly, while uninsured individuals experience a decrease in care.
A DNA rearrangement in immunoglobulin lambda (IgL) translocations is associated with poorer outcomes and reduced survival benefit from immunomodulatory drugs like lenalidomide. Patients with this genetic marker are more likely to relapse and die within the first three years after diagnosis.
Public health researchers suggest adjustments to Medicare rules to accommodate frequent hemodialysis treatment, which has shown mixed results. The proposed changes aim to give nephrologists greater clarity on payment for dialysis care, enabling them to identify better treatment options.
Researchers at Emory University found that Ginkgo seed extracts inhibit the growth of skin pathogens like Cutibacterium acnes, Staphylococcus aureus, and Streptococcus pyogenes. The study suggests ginkgo seeds could be used as a topical antimicrobial treatment for skin disorders.
Researchers found a small male advantage in mental rotation skills among children aged six to eight, with no difference detected among preschoolers. The study suggests that other factors may be more important than biology in driving the gender gap in spatial skills during childhood.
A new study found that adults with serious mental illness and substance use disorders are less likely to meet Medicaid work requirements due to their health conditions. Researchers warn policymakers to consider the accessibility of mental health treatment and exemptions for those affected by work requirements.
Researchers used an algorithm to model the decision-making of C. elegans in response to a sensory stimulus, achieving predictions that matched experimental results. The Sir Isaac platform demonstrated improved accuracy compared to prior models, offering insights into the potential of artificial intelligence in scientific discovery.
Researchers have found that modulating blood-forming stem cells' stiffness could help drive them out of the bone marrow and into the blood, but they need to be stiff to stay put. The study, published in Cell Stem Cell, suggests that altering cell biomechanics can improve mobilization regimens for stem cell-based therapy.
A new paper reviews key theories and methods to study puberty, highlighting its importance in understanding adolescent development and welfare. The review emphasizes the need to integrate sociological and psychological impacts into research models, as current approaches focus solely on biological processes.
A study of rat body sizes over time provides new evidence for the local environment during the time of Homo Floresiensis. The results indicate that the habitat was mostly open grasslands more than 100,000 years ago but shifted rapidly to a more closed forested environment around 60,000 years ago.
A new paper proposes that miniaturization is a central tendency in hominin technologies going back at least 2.6 million years. The researchers argue that tiny stone flakes were like disposable razor blades or paperclips, pervasive and easily replaced.
Scientists have discovered that deleting the gene encoding ASCT2, a transporter enzyme responsible for bringing amino acids into cells, prolongs survival of mice with aggressive leukemia. The study found that ASCT2 is required for leukemia development and progression but dispensable for normal blood cell development.
Researchers identified the first genetic defect linked to biliary atresia, a mysterious liver disease causing liver transplantation in children. The study found five patients with disabling mutations in the gene PKD1L1, which was also linked to heterotaxy and congenital heart disease.
Researchers found that packaging signals on the bird flu RNA genomes are incompatible with H3N2 viruses, limiting reassortment. However, low-level transmission of reassorted viruses was detected, particularly with H5N8 strains.
Researchers at Emory University discovered that electrical stimulation of the cingulum bundle can induce laughter and a sense of calm in patients undergoing brain surgery. The technique has potential applications in treating depression, anxiety disorders, and chronic pain via deep brain stimulation.
A randomized clinical study found that a diet low in free sugars significantly improved nonalcoholic fatty liver disease (NAFLD) in adolescent boys. The study showed a reduction in NAFLD from 25% to 17% in the intervention group, compared to a 20% reduction in the usual diet group.
A recent study published in the Journal of Allergy and Clinical Immunology analyzed data from the National Heart Lung and Blood Institute's Severe Asthma Research Program. The research found that African American patients are more likely to experience emergency hospital visits for asthma and have poorer asthma outcomes due to socioecon...
Researchers at Emory University have developed a high-throughput screening platform to identify small molecules that can enhance the ability of human immune cells to kill cancer cells. The platform, called HTiP, has identified compounds such as birinapant, which has shown strong evidence for its relevance as an immune enhancer.
A dirhodium catalyst makes an inert C-H bond reactive, turning chemical 'trash' to 'treasure.' The catalyst achieves exquisite control over the reaction, producing value-added molecules with high selectivity and minimal byproducts.
A new smartphone app uses fingernail photos to detect anemia with high accuracy, offering a non-invasive alternative to traditional blood tests. The app was developed by a biomedical engineer who lives with beta-thalassemia and aims to facilitate self-management for patients with chronic anemia.
Research suggests Zika virus may use the same immune transfer route as dengue to infect Hofbauer cells in the placenta, leading to increased viral binding and entry. This finding has implications for understanding Zika's ability to cross the placental barrier.
Ancient Andean populations adapted to high-altitude environment with distinct genetic changes, including a co-evolution between the potato and humans. The study suggests that these adaptations allowed them to thrive in extreme conditions.
Researchers identified a link between MIR-137 and complex brain disorders like autism spectrum disorder (ASD) and schizophrenia. Mice lacking MIR-137 displayed learning and memory deficits, repetitive behaviors, and impaired sociability, suggesting potential treatment targets.
Researchers found that very low troponin levels can rule out stress-inducible ischemia, allowing doctors to avoid routine stress testing. This could reduce healthcare costs and radiation exposure by triaging individuals with stable CAD before performing stress tests.
Researchers at Emory University have proposed a novel framework to explain schadenfreude, finding that it comprises three subforms: aggression, rivalry, and justice. These subforms are interrelated and rooted in concerns of self-evaluation, social identity, and justice.
Researchers found that dogs have a rudimentary neural representation of meaning for words they have been taught, differentiating between familiar and unfamiliar words. The study suggests dogs may not always understand the literal meaning of words but can infer their intended context.
Researchers discovered that cells in the cerebellum, or 'little brain', have unique metabolic needs. The study found that blocking an enzyme regulating mitochondria impairs cerebellar development more than other parts of the brain.
A recent study found that DN2 B cells, a type of immune cell, are expanded in people with systemic lupus erythematosus (SLE) and may be responsible for the production of autoantibodies. The research suggests that targeting these cells could provide new insights into treating the disease.
A new mathematical model describes the distribution of sensory errors in learning, revealing that animals explore and track a range of possibilities to compensate for variabilities. The study found that birds combine their hypotheses with new information from their ears while singing, surprisingly accurately.
A mathematical model for malaria shows that competition between parasite strains within a human host reduces the odds of drug resistance developing in high-transmission settings. The model reveals how once a drug-resistant strain becomes established, it will spread faster in high-transmission areas than in low-transmission areas.
Researchers at Yerkes National Primate Research Center have successfully reversed the effects of parental stress on offspring by exposing parents to behavioral interventions. The study found that this approach breaks the cycle of intergenerational stress, reducing sensitivity and structural imprints in offspring.
A new study finds that toddlers are attuned to how others may be judging them and modify their behavior accordingly. Children between 14 and 24 months show inhibition when being watched with a neutral or negative expression, but press the buttons associated with positive responses more often.
A team of Emory scientists has identified an enzyme that removes N6-methyladenine from Drosophila DNA, crucial for neuronal development. The finding provides insights into the role of this modification in humans, particularly in relation to Polycomb proteins.
Researchers identified MAST1 as an enzyme responsible for making tumors and cancer cells resistant to cisplatin. An experimental drug, leastaurtinib, targets this enzyme, potentially allowing reduced doses of cisplatin to reduce side effects.
Research shows that a pharmacological strategy can alleviate multiple behavioral and cellular deficiencies in a mouse model of fragile X syndrome. Treatment with GSK6A or a similar compound could be a viable strategy for addressing cognitive and behavioral problems in fragile X syndrome.
The National Academies have released a report on the intersection of opioid use disorder and infectious diseases, highlighting the urgent need for integrated treatment strategies. The report suggests five action steps to target both opioid use disorder and its resulting rise in infectious diseases, including screening for OUD, implemen...
A recent study found a significant link between cross-sex hormone use in transwomen and elevated risks of venous thromboembolism, stroke, and myocardial infarction. The study analyzed data from Kaiser Permanente health systems and compared rates of vascular events among transwomen to those in cisgender men and women.
Researchers found that humans working in ORs follow primate patterns of hierarchy and gender, with conflicts mainly occurring between team members from different ranks. The study also showed that cooperation varied by gender composition of the team, with less cooperation when there were more male members.
Researchers at Emory University have discovered that GluN2C is rarely paired with another subunit, challenging current understanding of NMDA receptors. This finding has implications for developing treatments for diseases such as schizophrenia and treatment-resistant depression.
Scientists have discovered a new compound that reactivates the BAI1 gene, blocking medulloblastoma growth in mice. The compound, KCC-07, targets a protein called Mbd2, which is involved in silencing genes.
Researchers have devised a method to study how light affects materials, shedding light on the fundamental laws governing electron-light interactions. The new approach enables better understanding of material behavior, which can be applied to improve devices such as optical sensors and photovoltaic cells.
Higher levels of bilirubin in the blood are associated with lower rates of heart failure, heart attack, and stroke, even in people without liver disease. The study suggests that bilirubin may have beneficial effects as an antioxidant, potentially reducing chronic disease morbidity risk.
Infant formulas with fructose or sucrose pose a risk to babies with hereditary fructose intolerance, who may experience acute liver failure if fed these sweeteners. Parents can avoid this risk by switching to formula without fructose and labeling products with explicit warnings.
A new study published in PNAS found that the brain's ventromedial prefrontal cortex plays a key role in forming expectations underlying effort-based choices. The study used fMRI to model neural computations for effort and reward, revealing a clear role for three brain regions: the vmPFC, dACC, and aI.
Scientists have developed a statistical framework to predict chikungunya and Zika outbreaks based on dengue fever 'hot spots'. The analysis used eight years of data from Merida, Mexico, and showed that people living in these hot spots had twice the rate of infection as those outside.
Researchers capture images of measles viruses as they emerge from infected cells, gaining insights into the internal organization and potential antiviral strategies. The study reveals a scaffold-like matrix protein acting as a framework for viral assembly.
The study found that the Tsimshian population's genetic diversity recovered after a collapse, with intermarriage increasing genetic diversity in some individuals. This contradicts previous notions of Native American populations expanding until European colonization.
Researchers connected microscopic theories to the world's largest granular material, a glacial ice mélange, to understand its dynamics and impact on glaciers. The study provides quantitative tools for glaciologists modeling ice shelves with ice mélanges.
Researchers have discovered a genetic switch in the bacteria that can be targeted by small molecules to prevent its virulent form from emerging. By disabling this switch, the bacteria become more vulnerable to host defense molecules and disinfectants, making it a potential key for new antibiotics.
Emory University's Yerkes National Primate Research Center has received a five-year, $12.7 million NIMH grant to continue research on oxytocin, a brain chemical involved in social bonding. The goal is to understand its role in neural communication and social functioning.