A genome-wide comparison of eastern and western monarch butterflies found they share identical genetic diversity, contradicting long-held assumptions about their distinctiveness. The study suggests environmental factors shape behavioral differences in the butterflies' migratory patterns.
Tiny finger-like projections called filopodia play a crucial role in invasive behavior of rare lung cancer cells. The cells have longer filopodia than their counterparts, which is linked to the gene MYO10, stabilizing these structures. This discovery could help develop treatments that prevent cancer from spreading.
Scientists have discovered a compound in the American beautyberry leaves that works in combination with oxacillin to knock down resistance to the drug methicillin-resistant Staphylococcus aureus, or MRSA. The study suggests a new potential therapy for treating antibiotic-resistant infections.
A study by Emory Vaccine Center found that adjuvants can strengthen both rookie and veteran elements of the immune response to a vaccine containing H5N1. This has significant implications for developing universal flu vaccines against multiple strains, as well as optimizing responses against SARS-CoV-2.
A $2.5 million Simons Foundation grant is supporting an international collaboration of neuroscientists to develop new tools for studying brain control over behavior across species, from songbirds to rats. The project aims to create a framework for understanding motor agility in any species or behavior.
A new adjuvant, 3M-052, has been shown to induce long-lasting immunity against HIV in a pre-clinical study involving 90 rhesus monkeys. The adjuvant successfully generated vaccine-specific, long-lived bone marrow plasma cells that maintained high numbers for over one year after vaccination.
Researchers have found that Zika virus infection soon after birth can lead to persistent socioemotional, cognitive and motor deficits, as well as abnormalities in brain structure and function. This study provides clues about potential long-term effects of Zika infection on developing brains.
Researchers have identified specific compounds from the Brazilian peppertree that reduce the virulence of antibiotic-resistant staph bacteria. The triterpenoid acids block the ability of bacteria to produce toxins, allowing the immune system to heal wounds more effectively.
Researchers developed a new HIV vaccine that combines neutralizing antibodies with cellular immunity to provide more effective protection. The vaccine showed promising results in preventing infection and lasting for over a year after vaccination.
A team of Emory scientists compared the most common inherited form of amyotrophic lateral sclerosis and frontotemporal dementia with spinocerebellar ataxia type 36. They discovered that protein products can poison cells in one disease but not the other, providing new insights into their pathological mechanisms.
Researchers at Emory University have achieved significant shrinkage of the viral reservoir in SIV-infected nonhuman primates using a combination of CTLA-4 and PD-1 inhibitors. However, this approach does not prevent or delay viral rebound when antiviral drugs are stopped. The findings have important implications for HIV cure research.
Researchers used a combination of CTLA-4 and PD-1 blockers to shrink the size of the viral 'reservoir' in SIV-infected monkeys. The treatment showed promising results, but did not prevent or delay viral rebound once antiviral drugs were stopped.
Researchers developed a rod-shaped DNA motor that rolls at speeds up to 100 nanometers per minute, breaking previous records. The motor uses RNA fuel and can travel the length of a human stem cell in two or three hours.
Researchers have discovered that newborns' brains show a strong connection between face and place processing networks just six days after birth. The findings suggest that babies are born with a specialized visual cortex, with patterns of brain activity similar to those of adults.
Researchers at Emory University have developed a new approach to organic synthesis that can efficiently transform simple molecules into complex ones with 3D structures. This method opens up whole new chemical space for potential drug targets, enabling the creation of more direct and efficient pathways for pharmaceutical research.
Researchers at Emory University found that mixing different molecular sizes of polymers within a solution increases the ability of a thin film to stretch without breaking. This discovery holds implications for improving industrial processes like oil flow through pipes and foam clearance in streams and rivers.
A study by Emory University psychologists found that individuals with certain personality traits, particularly psychopathy and meanness, are more likely to view others as mere sex objects. This attitude is associated with sexual objectification and can be a precursor to harassment and violence.
Researchers have successfully disrupted viral latency in monkeys and mice, a crucial step towards an HIV cure. The approach uses a combination of immune stimulation and depletion to reactivate the dormant virus, offering new avenues for treatment.
Scientists have developed a 'bilingual' molecule that combines DNA and protein codes, enabling communication between nucleic acids and proteins. The molecule holds potential for diagnostics, gene therapy, and drug delivery targeted to specific cells.
A study found that dogs process basic numerical quantities in the parietotemporal cortex, similar to humans. This suggests a shared neural mechanism for numerosity that may have evolved at least 80 million years ago.
Researchers discovered immune cells inside tumor samples can predict progression-free survival after surgery for kidney cancer. Patients with well-supported immune cells have longer disease control, leading to improved treatment options and potential adjuvant therapy trials.
Human screams share specific acoustic characteristics, including higher pitch and roughness, variability in frequency, and a wider range of sound waves. Listeners can readily distinguish screams from other human calls, highlighting the unique properties of this primal human call.
Researchers found that a decrease in CPC counts during an exercise test can predict high risk of heart attack or death over the next three years. Monitoring CPC response to exercise provides more information than nuclear imaging for cardiac ischemia, reducing radiation exposure.
Research on exhausted CD8 T cells provides clues for refining cancer immunotherapy. A new study defines a transitional stage between stem-like and truly exhausted cells, which could be a target for therapy.
Creating too many Th1 cells at mucosal sites compromises effective vaccine protection against HIV. Researchers have identified a key balance needed to stimulate the immune response without increasing susceptibility to the virus.
A new study by Emory University researchers found that college football players' weight gain leads to adverse changes in cardiac structure and function, including increased blood pressure and arterial stiffening. Early intervention is needed for this young and otherwise healthy athletic population.
Emory researchers have secured a $15.89 million NIAID contract to test the antiviral drug EIDD-2801 in human trials. The goal is to develop a better drug against influenza, which kills an average of 20,000 people annually in the US. EIDD-2801 has shown promising results in animal models and is effective against multiple RNA-based viruses.
A recent twin study published in the Journal of Alzheimer's Disease found a strong correlation between good cardiovascular health and improved cognitive function. The research suggests that adopting an ideal lifestyle with low CVH scores may not only reduce heart disease but also lower dementia risk.
A virtual town called 'Neuralville' was created to test brain function, revealing specialized cortical scene-selective regions for recognizing places and navigating through environments. The study has implications for brain rehabilitation methods and improving computer vision systems.
The National Institute on Aging has awarded a grant to establish the Open-AD Drug Discovery Center, which aims to accelerate the development of new drugs for Alzheimer's disease. The center will develop research platforms and openly distribute tools to test the efficacy of Alzheimer's therapies.
Researchers at Emory University School of Medicine identified CXCR6 and CXCL16 as critical molecules for T cells to travel to and populate the lungs. This discovery could lead to designing adjuvants that recruit CD8 T cells into the airways, potentially reducing symptoms or preventing infection.
Researchers are using DNA to build nanoscale devices that can generate, transmit, and sense mechanical forces. These devices have potential uses in drug delivery, nano computers, and nano robots, and could lead to breakthroughs in biomedical research and materials science.
Researchers at Emory University have created a flexible smart skin that changes color in response to heat and sunlight without altering its size. This innovation uses photonic crystals to mimic the chameleon's natural ability, opening doors for applications in camouflage, chemical sensing, and anti-counterfeiting.
The World Heart Federation's new roadmap outlines a vision for ideal CVD prevention pathways, highlighting gaps in care for people living with diabetes. Developed in partnership with the IDF, it presents an integrated approach to patient care and provides implementation tools for national initiatives.
A study by Emory Vaccine Center and CDC found immunity against mumps virus insufficient in a fraction of college-aged people who received MMR as children. The results highlight the need for better understanding of immune response to mumps and vaccines.
Researchers at Emory University found that the medial axis of an object, or its skeletal geometry, is a crucial visual tool for object recognition. The study suggests that this inner mechanism may play a more important role than previously thought in recognizing objects quickly.
Researchers at Emory University have identified a way to inhibit cancer cell growth by targeting the bottleneck enzyme ribonucleotide reductase. By regulating its active site, scientists hope to develop novel anticancer agents that preferentially target cancer cells.
A survey of 93 people with 3q29 deletion syndrome reveals a distinct pattern of social disability and anxiety, even without an autism spectrum disorder diagnosis. The study indicates a higher risk of autism spectrum disorder at a similar level to schizophrenia, particularly for females.
Researchers found signs of activation in resting B cells, which precede the activation of immune cells in people with systemic lupus erythematosus (SLE), a previously underappreciated stage of the disease. The study identified patterns of gene activity that could be used as biomarkers for disease development.
Researchers discovered Cas9's ability to block gene activity without cutting DNA in pathogenic bacterium Francisella novicida, regulating disease-causing genes. This finding expands the versatility of CRISPR/Cas9 for genome engineering and potential antibiotic resistance solutions.
Researchers at Emory University School of Medicine have developed an 'optochemogenetics' approach that modifies a widely used neuroscience tool to stimulate brain cells. The approach uses light to promote functional recovery in mouse models of stroke, with promising results for treating stroke patients.
Researchers used advanced imaging techniques to visualize macrophages in living mice with brain tumors, finding clear morphological and behavioral differences between blood-derived and brain-resident macrophages. Blocking macrophage infiltration improved survival in treated mice.
A study by Emory University scientists found that human screams can be correctly identified as belonging to the same person. The research suggests that non-human primates, like monkeys, also use screams for recruitment and help. This discovery sheds light on the evolutionary origins of screams.
Scientists at Emory Health Sciences have found that combining certain antibiotics can effectively target and defeat bacteria with heteroresistance, a previously underappreciated form of antibiotic resistance. This approach may offer a new strategy for treating resistant infections in hospitalized patients.
Researchers developed a machine-learning method to quantify semantic richness of conversational language, predicting psychosis with high accuracy. They analyzed sound-related words and low semantic density, detecting hidden patterns in people's language predictive of psychosis.
CHAMPS, a global health network at Emory University, has been awarded a $180 million grant to collect and analyze data on child mortality worldwide. The grant will help identify causes of high child mortality in sub-Saharan Africa and South Asia.
A new study suggests that chronic inflammation disrupts the brain's dopamine system, leading to motivational impairments in depression, schizophrenia, and other disorders. The researchers developed a computational method to test their theory, which may yield insights into treating cases of depression and behavioral disorders.
A new study finds that extracts from three Civil War-era plants have antimicrobial activity against multi-drug resistant bacteria, which were commonly used in treating wound infections. The research suggests these plant-based remedies may have saved limbs and lives during the war.
Researchers have revived an old approach to the Riemann Hypothesis using Jensen-Polya polynomials, providing a new framework for understanding prime numbers. The approach reveals a method to calculate the polynomials all at once, opening up new avenues for solving other fundamental mathematical problems.
Researchers found that Ebola survivors developed high levels of neutralizing antibodies months after recovery, which could inform the design of antiviral therapies and vaccines. The study's findings have implications for understanding immune protection after vaccination and developing effective treatments.