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Michigan Medicine - University of Michigan


Refinement of genetic signals for psoriasis by combining European-origin and South Asian populations

A Michigan Medicine study combined genetic samples from patients of different ethnic backgrounds, identifying two new psoriasis genetic signals. The inclusion of South Asian subjects allowed researchers to pinpoint several genetic variations within HLA genes that are likely to play a causal role in psoriasis.

SourceMichigan Medicine - University of Michigan·JournalHuman Genetics and Genomics Advances·TypeRandomized controlled/clinical trial·DateDec 2, 2021

Less than 10% of opioid overdose patients are prescribed potentially lifesaving medications after emergency treatment

A Michigan Medicine study found that only 7.4% of patients received naloxone and 8.5% received buprenorphine prescriptions within 30 days of an opioid overdose. The low rates highlight missed opportunities for equipping patients with rescue medicines to use in case of future overdoses.

SourceMichigan Medicine - University of Michigan·JournalAnnals of Emergency Medicine·TypeData/statistical analysis·DateNov 23, 2021

Medical training takes a mental toll, but less than a decade ago

A 13-year study tracked the mental health of new doctors during their most stressful time, showing a significant reduction in depression scores over the past decade. The study suggests that reduced work hours, increased sleep, more feedback from supervisors, and greater use of mental health care contributed to this change.

SourceMichigan Medicine - University of Michigan·JournalAnnals of Internal Medicine·TypeData/statistical analysis·DateNov 15, 2021

Pregnancy stretch marks cause stress and emotional burden, study finds

Researchers found that nearly 75% of pregnant women with stretch marks reported moderate to prominent embarrassment, which impacted their social activities, self-esteem, and clothing choices. The study highlights the need for open discussions about stretch marks to normalize them and identify potential mental health issues.

SourceMichigan Medicine - University of Michigan·JournalInternational Journal of Women’s Dermatology·TypeSurvey·DateNov 9, 2021

Service provides a lifeline for primary care providers amid a crisis in youth mental health made worse by the pandemic

The MC3 program provides a lifeline for primary care providers in Michigan, connecting them with psychiatrists and behavioral specialists for consultation and training. This has led to improved diagnosis and care for young people with mental health concerns, including those who express suicidal thoughts or have harmed themselves.

U-M Apple Watch Study provides an unprecedented look at the health status of a diverse patient population

The MIPACT study analyzed data from thousands of participants, revealing differences in heart rate, blood pressure, and activity levels by age, race, ethnicity, and clinical conditions. The study's findings have significant implications for clinicians, providing a more complete picture of daily life and resulting health.

SourceMichigan Medicine - University of Michigan·JournalThe Lancet Digital Health·DateOct 26, 2021

Transplants for alcohol-related liver inflammation surge during pandemic

During the pandemic, registrations for alcoholic hepatitis and deceased donor liver transplants increased by over 50%, associated with rising alcohol sales. Alcoholic hepatitis can lead to permanent scarring and long-term damage if left untreated, highlighting the need for public health interventions around excessive alcohol consumption.

SourceMichigan Medicine - University of Michigan·JournalJAMA Network Open·DateOct 26, 2021

Overdose deaths involving cocaine or meth tripled in shadow of opioid crisis

Overdose deaths involving cocaine or methamphetamine increased triply in the shadow of the opioid epidemic. Most fatal overdoses (70%) involved multiple substances, with most being opioids and stimulants. The study highlights disparities in overdose risk from stimulants among Black veterans and rural residents.

SourceMichigan Medicine - University of Michigan·JournalAddiction·TypeData/statistical analysis·DateOct 20, 2021

Treatment enhances anti-leukemia effect of bone marrow transplant, reduces recurrence, study finds

Researchers found that adding interferon to bone marrow transplant significantly reduced leukemia relapse among high-risk patients, improving outcomes. The study suggests a potential new strategy for treating advanced acute myeloid leukemia, with further research needed to confirm the findings.

SourceMichigan Medicine - University of Michigan·JournalBlood Advances·TypeExperimental study·DateOct 20, 2021

Patients hospitalized for COVID-19 this year could pay thousands of dollars, study suggests

A new study analyzed 4,000 COVID-related hospitalizations and found that patients with private insurance could face $3,800 bills, while those with Medicare Advantage plans might owe $1,500. The lack of waivers for hospitalization costs could lead to increased financial burden on patients.

SourceMichigan Medicine - University of Michigan·JournalJAMA Network Open·TypeData/statistical analysis·DateOct 18, 2021

Patients’ referral to primary care after COVID-19 hospitalization varied widely during the pandemic

Researchers found that only a quarter of patients were scheduled for primary care follow-up prior to discharge during the second wave, highlighting the need for improved healthcare system navigation. Outpatient care can help screen for physical and emotional impairments common among COVID and sepsis patients.

SourceMichigan Medicine - University of Michigan·JournalJournal of General Internal Medicine·DateOct 12, 2021

Pandemic took a toll on older adults serving as unpaid caregivers for chronically ill or disabled loved ones

A new study highlights the challenges faced by unpaid caregivers of chronically ill or disabled loved ones during the pandemic. The survey found that 60% of caregivers experienced at least one challenge related to accessing medical care for their loved ones, leading to increased stress, depression, and isolation.

SourceMichigan Medicine - University of Michigan·JournalInnovation in Aging·TypeSurvey·DateOct 6, 2021

Common diabetes drug promising against rare childhood brain tumor in laboratory studies

Researchers found that metformin suppressed glucose metabolism and killed cancer cells in group A posterior fossa ependymomas, a type of childhood brain tumor. The study's senior author believes this opens a promising possibility for therapeutic suppression of the epigenetic changes driving these tumors.

SourceMichigan Medicine - University of Michigan·JournalScience Translational Medicine·TypeExperimental study·DateOct 6, 2021

Survey finds a need for pet care during hospitalizations

A survey conducted by Michigan Medicine found that nearly two-thirds of respondents experienced difficulty with pet care during hospitalization or knew someone who did. This stress can impact a patient's decision about staying in the hospital. Researchers aim to develop better resources and formalized services to address this need.

SourceMichigan Medicine - University of Michigan·JournalJournal of Patient Experience·TypeSurvey·DateOct 5, 2021

Medicaid expansion closed health gaps for low-income adults across racial and ethnic groups, study shows

A new study from the University of Michigan finds that Medicaid expansion in Michigan has significantly improved access to regular healthcare services for low-income adults across various racial and ethnic groups. By 2018, 83% of Healthy Michigan Plan enrollees reported having a regular doctor's office, with notable increases seen amon...

SourceMichigan Medicine - University of Michigan·JournalHealth Affairs·TypeSurvey·DateOct 4, 2021

When a free cancer check finds something, could cost keep patients from following up?

New studies show that patients with abnormal screening results may face significant out-of-pocket costs for follow-up tests, potentially delaying care. For women, colposcopy costs rose sharply over 13 years, with some facing bills of nearly $1,000. Lung cancer screening CT scans also led to high costs for invasive procedures.

SourceMichigan Medicine - University of Michigan·JournalObstetrics and Gynecology·TypeData/statistical analysis·DateOct 1, 2021

ECMO life support offers sickest COVID-19 patients a chance to survive, but a slimmer one than once thought

A new study found that the survival rate of COVID-19 patients on ECMO has decreased over time, with those treated later in the pandemic having lower chances of survival. Careful patient selection and resource management are essential for hospitals offering ECMO to maximize survival rates.

SourceMichigan Medicine - University of Michigan·JournalThe Lancet·TypeData/statistical analysis·DateSep 29, 2021

COVID-19 antibodies persist, reduce reinfection risk for up to six months, study finds

A Michigan Medicine study found that most patients with mild COVID-19 infections produce antibodies that persist and protect them from reinfection for up to six months. Nearly 90% of participants produced spike and nucleocapsid antibody responses, and all but one had persistent antibody levels at follow-up.

SourceMichigan Medicine - University of Michigan·JournalMicrobiology Spectrum·TypeObservational study·DateSep 14, 2021

Turning 65 means a lot for Americans’ wallets, health spending study finds

A new study suggests that lowering the age when older adults can enroll in Medicare might save them a significant amount of money. The study found that average out-of-pocket healthcare costs dropped by 27% for those turning 66, while nearly 9% of 64-year-olds were considered 'catastrophic' due to high health expenses.

SourceMichigan Medicine - University of Michigan·JournalJAMA Health Forum·TypeData/statistical analysis·DateSep 13, 2021

As dementia’s toll rises, new study shows major gaps in who gets care that could help them remain at home

A new study highlights significant disparities in dementia care availability by gender, race, ethnicity, education level, and family structure. The findings emphasize the importance of family caregivers, with those having available spouse or adult child support being less likely to move into nursing homes.

SourceMichigan Medicine - University of Michigan·JournalHealth Affairs·TypeObservational study·DateSep 8, 2021

Why do people with diabetes develop severe COVID-19?

A study from Michigan Medicine found that people with type 2 diabetes are more likely to develop a cytokine storm during coronavirus infection due to the enzyme SETDB2. Administering interferon beta increased SETDB2 and decreased inflammatory cytokines in diabetic mice, offering potential therapy for severe COVID-19.

SourceMichigan Medicine - University of Michigan·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateSep 7, 2021

Symptoms, like pain and fatigue, often cluster in newly diagnosed MS, study finds

A recent Michigan Medicine study found that people newly diagnosed with multiple sclerosis experience a myriad of significant symptoms that often cluster together. Nearly two-thirds of MS patients reported fatigue, half experienced pain in the first year after diagnosis. The research team collected questionnaires from MS patients at si...

SourceMichigan Medicine - University of Michigan·JournalMultiple Sclerosis Journal·TypeData/statistical analysis·DateAug 20, 2021