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Michigan Medicine - University of Michigan


Many older adults look beyond conventional medicine for help, but few talk to their doctors about it

According to a new poll, nearly 40% of older adults (50-80) use at least one integrative medicine strategy to alleviate symptoms or relax. However, only 18% discuss these strategies with their healthcare providers. The poll highlights the importance of primary care clinicians discussing integrative approaches with patients.

Finding the right memory strategy to slow cognitive decline

A new study led by researchers from the University of Michigan and Penn State College of Medicine compared two approaches for people with early form of memory loss: mnemonic strategy training and spaced retrieval training. Mnemonic strategy training showed increased brain activity in areas often affected by Alzheimer's disease, while s...

SourceMichigan Medicine - University of Michigan·JournalAlzheimers Disease & Dementia·TypeRandomized controlled/clinical trial·DateJul 22, 2022

Patient deterioration predictor could surpass limits of traditional vital signs

Researchers developed an AI-driven device that detects and predicts hemodynamic instability using a single ECG lead, outperforming traditional vital sign measurements with nearly 97% sensitivity. The technology has the potential to provide continuous dynamic monitoring capabilities in patients with intermittent static vital sign measur...

SourceMichigan Medicine - University of Michigan·JournalCritical Care Explorations·TypeExperimental study·DateJul 21, 2022

Costs for emergency allergy injectors still high for some?

A new study found that while the availability of lower-priced epinephrine auto-injector competitors has improved affordability for many patients, a significant minority still pay significantly more for life-saving medication. High-deductible health plans are a major contributing factor to these high costs.

SourceMichigan Medicine - University of Michigan·JournalJournal of General Internal Medicine·TypeData/statistical analysis·DateJul 12, 2022

Opioid prescriptions significantly higher for patients with lifelong disabilities, study finds

A Michigan Medicine study found that people with cerebral palsy and spina bifida are prescribed opioids at a rate up to five times higher than those without the conditions. Chronic pain is the most commonly reported symptom among these individuals, raising concerns over addiction and overdose issues.

SourceMichigan Medicine - University of Michigan·JournalHeliyon·TypeData/statistical analysis·DateJul 7, 2022

Study of pre-teens yields surprises about alcohol, tobacco and marijuana

A new study reveals that up to 10% of pre-teen children are curious about using substances, with boys more likely than girls to be interested. Parents' rules and home access play a significant role in shaping their children's curiosity, with Black parents being more likely to set rules against substance use.

SourceMichigan Medicine - University of Michigan·JournalDrug and Alcohol Dependence Reports·TypeSurvey·DateJul 1, 2022

Winning by default: Tonsillectomy study shows power of pre-set opioid Rx size

A new study found that hospitals can reduce excessive opioid prescribing by implementing an evidence-based default setting for opioid prescriptions written in electronic health records. The study showed that patients who received a standard prescription size with a lower default dose of opioids had similar pain control, but took home f...

SourceMichigan Medicine - University of Michigan·JournalJAMA Network Open·TypeObservational study·DateJun 30, 2022

Dynamic cells linked to brain tumor growth and recurrence

A study by Michigan Medicine researchers has identified oncostreams, highly active cells connected to brain tumor growth and invasion. The team found that eliminating Collagen 1 production from tumor cells reduces tumor aggressive behavior. This discovery could lead to novel therapeutic targets for treating lethal brain tumors.

SourceMichigan Medicine - University of Michigan·JournalNature Communications·TypeExperimental study·DateJun 28, 2022

How MRI and CT predict flap failure after head and neck reconstructive cancer surgery

Researchers used CT and MRI perfusion techniques to analyze 19 patients with successful free flap reconstruction and five with wound failure. The study found that both methods showed significant differences between the two patient groups. Early postoperative scans could help surgeons intervene earlier, potentially reducing hospital stays.

SourceMichigan Medicine - University of Michigan·JournalAmerican Journal of Neuroradiology·TypeRandomized controlled/clinical trial·DateJun 23, 2022

High fat diet, unregulated athletic exercise endurance enhancers linked to risk of pancreatic cancer

A study found that high fat diets and synthetic substances in unregulated athletic performance enhancers can activate a receptor accelerating the progression of pre-cancerous lesions to pancreatic cancer in mice. Limiting exposure to these substances may help prevent pancreatic cancer development.

SourceMichigan Medicine - University of Michigan·JournalNature Communications·TypeExperimental study·DateJun 1, 2022

What will it take to transform obesity care for all?

The US healthcare system faces a significant challenge in providing high-quality, personalized obesity care due to lack of insurance coverage for effective medications and societal stigma. Recent efforts aim to address this issue through framework development and policy changes, which may lead to improved patient outcomes and cost savi...

SourceMichigan Medicine - University of Michigan·JournalPrimary Health Care Research & Development·TypeObservational study·DateMay 31, 2022

Good news, bad news on risky medication use in nursing homes

A decade-long effort to reduce medication risks for nursing home residents with dementia has shown some positive results, but also unintended consequences. Fewer people are receiving antipsychotic and anti-anxiety drugs, which can raise the risk of falling or dying, but more are receiving alternative behavior-changing medications with ...

SourceMichigan Medicine - University of Michigan·JournalAmerican Journal of Psychiatry·TypeData/statistical analysis·DateMay 31, 2022

Common prostate cancer medications may be less safe than previously thought

Research found that men taking abiraterone or enzalutamide plus hormone therapy had a higher risk of metabolic and cardiovascular issues than those undergoing hormone therapy alone. This increased risk was observed in patients with Medicare health insurance, who were significantly older than those in clinical trials.

SourceMichigan Medicine - University of Michigan·JournalJNCI Journal of the National Cancer Institute·DateMay 25, 2022

Study finds nanomedicine targeting lymph nodes key to triple negative breast cancer treatment

Researchers found that targeting both tumor and lymph node microenvironments with nanomedicine improves treatment response for metastatic triple negative breast cancer. Long-term tumor remission was achieved in mice models using nanoparticles to deliver immune-modulating drugs.

SourceMichigan Medicine - University of Michigan·JournalScience Translational Medicine·TypeExperimental study·DateMay 12, 2022

A new approach to medical guidelines, taking inspiration from Wikipedia

Researchers developed a novel 'Wikiguideline' approach to establish medical guidelines, leveraging online collaboration and high-quality data. The method was tested using osteomyelitis, an infection of the bone, and found sufficient data for only two recommendations: increasing oral antibiotic therapy and limiting therapy duration.

SourceMichigan Medicine - University of Michigan·JournalJAMA Network Open·TypeSystematic review·DateMay 10, 2022

Operating rooms are the climate change contributor no one’s talking about

Surgeons-in-training suggest reducing waste, switching to reusable devices and gowns, optimizing OR energy use, and delivering care via telemedicine to lower climate impact. Implementing these changes can help extend patient lifespan and expand access to timely care while addressing climate change.

SourceMichigan Medicine - University of Michigan·JournalJournal of Clinical Oncology·TypeCommentary/editorial·DateMay 6, 2022

Study finds healthy-appearing lupus skin predisposed to flares, rashes

Researchers found that normal-appearing lupus skin contains the same inflammatory signals as skin with rashes, suggesting a primed state for inflammation. The study's findings provide new insights into how UV light triggers rashes in lupus patients and highlight the potential for precision medicine in treating the disease.

SourceMichigan Medicine - University of Michigan·JournalScience Translational Medicine·TypeExperimental study·DateMay 3, 2022

New studies show special mental health risks for certain groups of new doctors

Two new studies found that surgical interns and LGBTQ physicians-in-training experience higher rates of depression than their peers. Surgical interns who identified as female or had a history of adverse childhood experiences were also at increased risk. The studies add to the growing body of knowledge about mental health concerns in me...

SourceMichigan Medicine - University of Michigan·JournalJAMA Health Forum·TypeObservational study·DateApr 29, 2022

Simple changes in care reduced heart exposure during lung cancer radiation treatment

Raising awareness about cardiac radiation exposure reduced the number of patients receiving high heart doses in lung cancer patients. The study found that standardized cardiac dose constraints improved patient care without minimizing tumor treatment or increasing dosage to other at-risk organs.

SourceMichigan Medicine - University of Michigan·JournalPractical Radiation Oncology·TypeExperimental study·DateApr 8, 2022

Study: Older adults with rheumatoid arthritis still undermedicated, despite aggressive guidelines

A recent study suggests that many older adults with rheumatoid arthritis are not prescribed disease-modifying medications, despite guidelines calling for early and aggressive treatment. Only 45% of patients over 65 were prescribed these medications, highlighting the need to improve prescribing practices among primary care physicians.

SourceMichigan Medicine - University of Michigan·JournalACR Open Rheumatology·TypeObservational study·DateApr 7, 2022