Researchers at Nagoya University have discovered three new biomarkers for high-grade serous ovarian carcinoma using membrane proteins and polyketone-coated nanowires. The study reveals that small extracellular vesicles containing these proteins can be used to detect ovarian cancer, potentially leading to personalized medicine.
Researchers at Nagoya University found that Arctic dust is a significant source of particles forming ice crystals in Arctic low-level clouds. The findings suggest that Arctic dust can act efficiently as an ice nucleating particle, increasing the number of ice nucleating particles by over 100 times.
Researchers have developed a method to produce highly active mRNA vaccines at high purity using a unique cap to easily separate the desired capped mRNA. This 'Purecap' technique extracted up to 100% pure Cap2-type mRNA, which showed improved protein production and lower immunostimulatory activity.
Researchers at Nagoya University developed an AI-based technique to predict crystal orientation in polycrystalline materials, revolutionizing the industry. The method uses optical photographs and reduces measurement time from 14 hours to 1.5 hours, enabling large-area materials analysis.
Researchers at Nagoya University developed a nanosheet device with the highest energy storage performance yet seen. The device achieved a 1-2 orders of magnitude higher energy density while maintaining high output density and stability over multiple cycles.
Researchers have developed a technology to capture and release cell-free DNA from urine using nanowire surfaces, successfully detecting IDH1 mutation in glioma patients. This method opens possibilities for the detection of other tumor mutations and could revolutionize cancer diagnosis.
A research group at Nagoya University used AI to determine that Piezo plays a crucial role in controlling the mating posture of male fruit flies. Inhibition of Piezo led to an ineffective mating posture, resulting in decreased reproductive performance.
Researchers discovered that a diet rich in the bacteria Lactobacillus reuteri can maintain associative learning ability in older nematodes. This finding suggests potential ways to use diet to reduce age-related cognitive decline in other animals, including humans.
Researchers at Nagoya University have discovered that targeting Fusobacterium bacteria can reduce the formation of lesions associated with endometriosis. The study suggests an effective non-hormonal antibiotic treatment for this gynecological disorder, which affects one in ten women between 15 and 49 years old.
An international team found that volcanic eruptions can produce equatorial plasma bubbles in the ionosphere, disrupting satellite-based communications. The Tonga eruption triggered an irregular structure of electron density across the equator, delaying radio waves and degrading GPS performance.
Researchers at Nagoya University have developed a new technology to fabricate high-quality nanosheet films in about one minute. The method uses an automated film-forming process that produces neatly tiled monolayer films with no gaps between the nanosheets.
Researchers at Nagoya University have found that ATP, an energy 'currency' within cells, acts as a neurotransmitter in the brain and causes mammalian ovulation. Administering ATP to rats induced the LH surge leading to ovulation, suggesting a potential new treatment for infertility.
Researchers used AI to analyze speech patterns of patients with Parkinson's disease, finding they spoke in shorter sentences with more verbs and fewer common nouns. The study suggests potential early detection methods for the condition through conversational analysis.
Researchers developed glass filters to capture tumor cells from blood samples, enabling more efficient culture of these cells. The optimized filter design enhances the accuracy of cancer detection, allowing for earlier treatment and improved patient health.
Researchers at Nagoya University have successfully developed an ultrafast and simple synthetic method for producing indole derivatives. The new microflow synthesis method enables precise control of short reaction times, limiting unwanted dimerization/multimerization and increasing the yield of desired products.
A study published in Neurobiology of Disease suggests that targeting the sigma-1 receptor and ATAD3A protein may prevent mitochondrial dysfunction in ALS. The researchers found that this approach could lead to a novel therapeutic strategy for neurodegenerative diseases.
Researchers at Nagoya University have successfully synthesized barium titanate nanosheets with a thickness of 1.8 nanometers, the thinnest freestanding film ever created with ferroelectric properties. This achievement paves the way for the development of smaller and more efficient devices such as memories and capacitors.
Nagoya University researchers have developed a poly(styrenesulfonic acid)-based PEM with an ultrahigh density of sulfonic acid groups, exceeding five times that of typical commercially available membranes. The new membrane exhibits a proton conductivity of 0.93 S/cm at 80°C under 90%RH, six times higher than Nafion or Selemion under th...
Researchers at Nagoya University used PESI/MS/MS to analyze anthocyanins in crops, detecting 81 types of compounds in just 3 minutes. This technique simplifies and accelerates the analysis of plant metabolites, which contribute to crop quality and functionality.
Researchers at Nagoya University found an alternative route for microglia colonization in the embryonic brain, suggesting a novel approach to combat diseases like fetal brain dysfunction. Macrophages can convert into microglia later in development, providing new insights into microglial plasticity and behavior.
Researchers developed an optimized genome-editing method that vastly reduces mutations, enabling more effective treatment of genetic diseases. The new technique uses a 'safeguard gRNA' to control DNA cleavage, reducing off-target effects and cytotoxicity.
Researchers at Nagoya University found that localized IDH wild-type histologically diffuse astrocytomas have a poor prognosis similar to the most malignant types of brain and spinal cord tumors. This highlights the importance of proper clinical diagnosis and treatment for patients with gliomas.
Researchers at Nagoya University discovered three new species of bioluminescent polycirrus worms emitting blue-violet light, with names inspired by yokai from Japanese folklore. The findings aim to deepen understanding of bioluminescence mechanisms and potentially lead to new life sciences technologies.
A research group at Nagoya University discovered that the Japanese longicorn beetle has a symbiotic yeast called Scheffersomyces insectosa. The yeast breaks down xylose and other wood components, making it edible for the beetles.
A study published in Cell Death & Disease reveals that a protein cross-linking enzyme called TG2 exacerbates kidney fibrosis by polarizing M2 macrophages. The researchers hope to develop treatments for diseases caused by inflammation imbalance, such as fibrosis, cancer, and atherosclerosis.
A study by Nagoya University researchers identified three intestinal bacteria - Collinsella, Ruminococcus, and Bifidobacterium - linked to dementia with Lewy bodies. These findings may help diagnose and treat the neurodegenerative disease, with potential therapeutic interventions targeting specific bacteria.
A study found that BRCA1 mutations increase the risk of malignant mesothelioma caused by asbestos exposure. People with this genetic defect are more susceptible to tumor growth due to impaired ferroptosis defense mechanisms.
Researchers at Nagoya University developed a new dry etching method for metal carbides, allowing for the selective removal of TiAlC from other compounds. This technique enables the fabrication of gate-all-around transistors with improved performance and reduced leakage.
Researchers found that fasudil reversed reduced pyramidal neuron density and cognitive dysfunction associated with methamphetamine treatment in mice with ARHGAP10 gene mutations. Fasudil also restored the density of pyramidal neurons, improving visual discrimination tests performance.
A research group at Nagoya University has sequenced 95.6% of the Nicotiana benthamiana genome using next-generation sequencing technology. The findings provide insight into the plant's ability to perform grafting, a rare phenomenon in plants.
Scientists at Nagoya University developed an index to estimate a bird's wing use based on coracoid bone strength and body mass. This new tool sheds light on how ancient birds evolved to fly, including the flapping abilities of extinct species.
A study at Nagoya University found that specific neurons in fruit flies process and distinguish between different courtship songs, differing between species. The researchers used calcium imaging to determine how these neurons respond to different courtship songs, finding that the responses varied between species.
Researchers developed a new device to identify key membrane proteins in urine indicative of brain tumors. This could lead to early detection and increased survival rates for patients.
Researchers from Nagoya University have identified two microRNAs that are downregulated in systemic lupus erythematosus, a disease where the immune system attacks itself. The study found that these miRNAs regulate the same set of genes through 'seed overlap' co-targeting, which negatively regulates inflammatory cytokine production.
A recent study published in Science Advances has deepened the understanding of circadian rhythm regulation in mammals. The research found that intracellular cyclic adenosine monophosphate (cAMP) is controlled by a neural network, whereas calcium ions are regulated by intracellular mechanisms.
Researchers observed energy transfer from resonant electrons to whistler-mode waves in space, confirming non-linear growth theory. This finding improves understanding of space weather's impact on satellites and could help protect astronauts.
A study by Nagoya University researchers has identified EP3 neurons as crucial in maintaining a stable body temperature of 37°C in mammals. The discovery could lead to the development of technologies that artificially adjust body temperature to treat heat stroke, hypothermia, and obesity.
A Nagoya University study found that increased use of pharmaceuticals and medical supplies during the COVID-19 pandemic contributed to a 27% increase in hospital carbon emissions. Despite reduced electricity and gas consumption, the overall carbon footprint rose due to longer hospital stays and increased intensive care needs.
Researchers created a magneto-impedance sensor magnetometer that measures Earth's geomagnetic field fluctuations, enabling real-time monitoring of space weather and advancement of space research. The device is lightweight, power-efficient, and low-cost, making it suitable for constructing multi-point observation networks.
Researchers at Nagoya University discovered that when Ceratocystis ficicola and Fusarium kuroshium fungi are combined, fig saplings experience rapid wilting. The two fungi work together to cause more damage than either one alone, highlighting the importance of considering co-occurring microorganisms in disease control strategies.
Researchers from Nagoya University found that 5G network telemedicine is effective in providing telerehabilitation and teletreatment in a remote community. The study showed that 5G transmitted high-definition images with low latency, reducing the need for physical therapist visits and improving patient outcomes.
The study found that COVID-19 restrictions led to decreased balance ability, higher body fat levels, and worsened lifestyle habits in Japanese children. The researchers suggest that quality of exercise, rather than quantity, was the main factor contributing to these changes.
A study from Nagoya University reveals that atmospheric secondary particle formation influences the number of cloud condensation nuclei in remote areas. This leads to a greater cooling effect by clouds on climate change. The research aims to improve climate model accuracy and predict future climate change.
Researchers at Nagoya University have uncovered the mechanism behind ruthenium phosphide's transition from metal to insulator, revealing a unique crystal structure and molecular bonding. This discovery could lead to the development of faster responding sensors and smart windows that change light transmittance depending on temperature.
Researchers at Nagoya University have achieved a breakthrough in developing deep-ultraviolet laser diodes, which could revolutionize applications such as sterilization and medicine. The team successfully reduced the operating power needed for continuous-wave lasing to just 1.1W at room temperature.
Researchers at Nagoya University have developed a new method to control mosquito populations by altering the frequency of sound that males listen for. By using serotonin-inhibiting compounds, they reduced the range of frequencies males respond to and their response itself.
Researchers at Nagoya University discovered that grass puffer fish use a non-toxic version of their deadly toxin, TDT, to attract mates and warn off predators. The study found that TDT serves as an odorant, activating specific olfactory sensory cells in the fish's brain.
Researchers develop new technique to observe plasmons inside gold nanoparticles, revealing relaxation process with implications for energy conversion and development of light-harvesting materials. The ultrafast electron microscope enables analysis of ultrafast light-matter interactions at the nanoscale.
Researchers at Nagoya University analyzed three historical writings to identify past solar eclipses in Hokkaido, using modern scientific techniques. They found that these accounts matched computer simulations of the Sun and Moon positions, revealing valuable clues about the extremity of the solar-terrestrial environment.
Researchers at Nagoya University have developed a new method to study the life cycle of tree roots, shedding light on the decomposition process. They found that fine roots, which control nutrient uptake by trees, are discarded and decompose differently than leaf litter.