A recent study published in Scientific Reports found that the degree of platelet reduction is more strongly linked to mortality risk in sepsis than absolute platelet count. The researchers also discovered that a significant decrease in platelet count increases the risks of bleeding and thrombosis development.
Researchers found that electron precipitation from northern lights causes local ozone layer depletions in the mesosphere, potentially impacting climate. The study provides insight into this phenomenon, known as pulsating aurorae, and highlights its significance for global climate change.
Researchers at Nagoya University have successfully created graphene-diamond junctions that mimic key brain functions such as synaptic plasticity and excitatory postsynaptic current. These junctions exhibit photo-sensing and photo-controllable functions similar to those performed by the brain and retina.
A subset of fibroblasts in lungs of people with idiopathic pulmonary fibrosis (IPF) produce a protein called meflin, which protects against cell aging and fibrosis. Further research could lead to novel therapies for lung fibrosis.
Researchers at Nagoya University have observed a new type of topological defect in chiral magnets, which has implications for fields of physics and technology. The team used Lorentz transmission electron microscopy to visualize the defects, revealing contrasting pairs of bright and dark areas.
Researchers from Nagoya University have successfully measured the shape distributions of cell-derived nanoparticles, or extracellular vesicles, in body fluids. This study may help identify types of cancer with a painless and non-invasive method.
A study by Nagoya University researchers reveals that cohesin's ring needs to open for certain processes, like DNA replication and chromosome segregation. This opening facilitates the progressive replication of the DNA double helix and allows DNA looping, crucial for regulating gene expression.
Researchers at Nagoya University have developed a simple urine test that can detect brain tumors with high accuracy, using microRNAs as biomarkers. The new device can extract more microRNAs from just a milliliter of urine than conventional methods, and shows promise for early diagnosis and treatment.
Researchers at Nagoya University identified a key enzyme that activates nitrate uptake mechanisms in plants responding to nitrogen starvation. The CEPH protein plays a critical role in activating the high-affinity transport system, which enables rapid nitrate uptake from the environment.
Researchers observed plasma jets interacting with magnetic fields in a massive galaxy cluster 600 million light years away. The findings can help clarify how such galaxy clusters evolve, providing new insights into the structure of intracluster magnetic fields.
Nagoya University researchers discovered a molecular pathway that enhances chemotherapy resistance in some pancreatic cancer patients. Targeting the taurine upregulating gene 1 (TUG1) RNA could improve patient response to therapy and increase overall survival.
Researchers at Nagoya University discovered a DNA-like molecule called XNA that could be synthesized without enzymes, supporting the hypothesis of an XNA world before the RNA world. The findings suggest that XNAs can carry genetic code stably and potentially transfer genetic information between DNA and RNA.
Researchers from Nagoya University developed a two-step labeling technique to analyze the dynamics of neurotransmitter receptor proteins. The study revealed key findings on AMPA-type glutamate receptors, including their localization at synapses and half-life in neurons.
Researchers at Nagoya University identified a gene that enables African clawed frog tadpoles to regenerate nerves. Introducing this gene into mice with spinal cord injuries led to partial recovery of motor functions. The study suggests a new therapeutic approach for treating spinal cord injuries.
Scientists at Nagoya University have found that an electric accelerator for auroras exists much higher in space than previously thought, beyond 30,000 kilometres above the Earth's surface. This finding offers insight into Earth and other planets as well, shedding light on the process of aurora formation.
Researchers at Nagoya University have found catalysts that improve an important industrial reaction, producing high yields of a compound used in various industries without toxic compounds or high temperatures. The approach offers a practical and sustainable solution for industrial (meth)acrylate ester synthesis.
Researchers at Nagoya University have developed a new imaging technique that can assess the quality of high-energy muon beams. This innovation allows for better understanding and control of these beams in various applications such as non-destructive X-ray fluorescence spectroscopy and cancer radiotherapy.
Researchers at Nagoya University have discovered two types of fibroblasts, meflin and gremlin 1, that play a crucial role in regulating colorectal cancer progression. Altering the balance between these cells could be an effective strategy for preventing cancer progression.
Researchers from Nagoya University have developed a new class of super-hard composite materials by adding zirconium atoms to aluminum oxide and tungsten carbide. The resulting materials exhibit exceptionally high bending strengths greater than 2 gigapascals, making them stronger than previous CMCs.
Researchers at Nagoya University found that KNDy neurons, expressing kisspeptin, neurokinin-B, and dynorphin-A, are responsible for GnRH pulses, enabling ovarian function in mammals. Rescuing just 20% of these neurons is sufficient to restart GnRH and gonadotropin pulses and maintain fertility.
Researchers at Nagoya University found that blood pressure, hematocrit, and serum cholesterol levels change in patients with Parkinson's disease long before the onset of motor symptoms. These biomarkers may help detect early signs of developing Parkinson's disease.
Researchers at Nagoya University have discovered a rare mineral in the thick walls of a decommissioned nuclear power plant that increases concrete strength by more than three times. The formation of aluminous tobermorite allows for stronger and more eco-friendly concrete.
Researchers at Nagoya University have discovered a novel approach to tile functional nanosheets in a single layer using a one-drop method. This process could lead to the development of next-generation oxide electronics, enabling transparent and flexible devices.
Researchers from Nagoya University have determined the three-dimensional structures of RNA hybridization with artificial nucleic acids, revealing a new mechanism for stable binding. The study's findings challenge current knowledge on ribose's role in forming stable duplexes and open up avenues for novel drug designs.
Researchers at Nagoya University have identified a new compound responsible for the synthesis of anthocyanin pigment in black soybeans, shedding light on the biosynthetic pathway and potential applications for treating metabolic diseases. The study aims to clarify the full steps of cyanidin-3-O-glucoside synthesis in black soybeans.
A team of researchers led by Nagoya University has discovered that killer electrons, resulting from the pulsating aurora, could be involved in ozone destruction. The high-energy electrons are believed to cause damage when they penetrate satellites, and their presence in the middle atmosphere is associated with the pulsating aurora.
Researchers have identified a neural pathway that links the circadian clock, stress, and wakefulness in mammals. The study found that excessively active corticotropin-releasing factor neurons triggered insomnia and other sleep disorders when the circadian rhythm was disturbed.
Researchers at Nagoya University have discovered a way to harness energy from living cells by modifying highly functionalized PCAs into biorenewable molecules. The new catalyst enables the selective hydrogenation and dehydration of Krebs cycle metabolites, producing compounds with valuable applications in plastics and polymers.
A new study reveals that astrocytes can remove cellular debris from the brain when microglia are impaired. This finding could lead to new therapies accelerating debris clearance and reducing neurodegenerative diseases.
Researchers at Nagoya University have directly observed the spatial distribution of a single valence electron in titanium oxide, revealing a butterfly-shaped distribution. The new Fourier synthesis method, called core differential Fourier synthesis (CDFS), can determine orbital states in materials regardless of their physical properties.
The researchers synthesized a unique molecule that absorbs near infrared light, despite having only hydrogen and carbon atoms. The molecule's narrow gap between its highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) makes it useful for developing next-generation solid-state materials.
A study on the Orobanchaceae parasitic plant Phtheirospermum japonicum reveals that β-1,4-glucanase enzyme is crucial for both plant parasitism and cross-species grafting. The enzyme facilitates cell-cell adhesion and transport of water and nutrients between the parasite and host plants.
Nagoya University scientists have developed a laboratory technique to rapidly select synthetic proteins that strongly bind to SARS-CoV-2. The approach, called TRAP display, could be used to develop sensitive antigen tests and neutralization antibodies for infected patients.
A new study by Nagoya University reveals that narrow-range ultraviolet LED irradiation increases serum vitamin D levels and prevents the loss of bone and muscle mass in aging mice. This safe and stable method could be a promising approach for preventing and treating osteosarcopenia, a condition affecting daily life.
Researchers found that Nicotiana promotes tissue adhesion and maintains grafts with a broad range of species. The study successfully grafted a tomato scion onto a Florist's daisy rootstock, producing a small fruit.
Researchers discovered a novel role of tau specific to FTLD spectrum diseases, contributing to conditions like ALS, PSP, and CBD, but not AD and Pick's disease. The study proposes an imbalanced accumulation of tau model, where FUS and SFPQ regulate MAPT processing, leading to increased 4-repeat tau levels.
Scientists at Nagoya University discovered two genes, ACE1 and DEC1, that counteract each other to regulate rice plant stem growth. The findings suggest a new approach for genetically modifying rice crops to improve yield and adaptability.
Scientists at Nagoya University found that a thin top layer of azobenzene-containing plastic film needs to be light-sensitive to induce movement. The discovery could lead to cost reductions and revolutionize the material's use in various industries.
A physics-based model predicts imminent large solar flares with high accuracy, using a double-arc instability theory. The kappa scheme has been tested on 200 active regions and demonstrated its effectiveness in predicting solar flare occurrence and location.
Researchers at Nagoya University have found the mechanism of the night-to-day transition of the circadian rhythm in green algae. By controlling the activity of ROC75, they can wake up green algae and enhance their photosynthetic activities to produce larger amounts of lipids.
Researchers at Nagoya University found a highly unusual atomic configuration in a tungsten-based material, where three atoms share only two electrons to form a tritungsten molecule. This discovery suggests the potential for compounds with new and interesting electronic properties.
A pre-brain surgery test using navigated repetitive transcranial magnetic stimulation (nrTMS) accurately maps language centers in patients with brain tumors not involved in these areas. The method's accuracy varies depending on tumor involvement, but it shows promise for improving surgical planning and patient outcomes.
A Nagoya University team has discovered a process called allosteric regulation in plants, which helps maintain the balance of phytohormones gibberellin and auxin. This finding could lead to improved rice crop productivity and provide a solution for food security.
Researchers at Nagoya University have developed a near-infrared photoimmunotherapy (NIR-PIT) treatment targeting podoplanin-positive cells in malignant pleural mesothelioma (MPM). NIR-PIT has shown promise in reducing fluorescence from cancer-tagged cells and demonstrating anti-cancer effects.
Researchers at Nagoya University developed a micrografting device to facilitate the grafting of embryonic shoots onto tiny stalks, achieving a 48-88% success rate. The device shows potential for facilitating research into plant signalling and has been applied in tomato grafting.
A Phase 2 clinical trial has shown a novel treatment protocol to be effective in patients with intravascular large B-cell lymphoma (IVLBCL), achieving two-year survival rates of up to 76% and overall survival rates of 92%. The treatment, combining conventional drugs with high-dose methotrexate and intrathecal chemotherapy, has been fou...
A team of scientists from Nagoya University found that starving medaka larvae can cause sex reversal, revealing a potential link to environmental factors and metabolic processes. The study may provide insights into rare conditions in humans and other vertebrates where individuals have characteristics of both sexes.
A neural circuit in deep brain areas drives physical responses to emotional stress, including increased blood pressure and heart rate. Blocking this circuit may help reduce stress symptoms in rats, suggesting a potential target for treating stress-related disorders like panic disorder and PTSD.
Researchers at Nagoya University have created a new material that can efficiently charge Internet-of-Things (IoT) devices using body heat. The breakthrough involves adding an ion electrolyte gel to a conducting polymer, which untwists the polymer chain and creates links between its crystalline parts, improving electron conductivity.
Researchers at Nagoya University have discovered a hormone produced in nitrogen-starved leaves that regulates the demand and supply of nitrogen between plant shoots and roots. The hormone, CEPDL2, enhances nitrate uptake efficiency, potentially minimizing fertilizer use.