Researchers at Nagoya University have developed a new approach to metal catalysis that selectively converts biomass into high-value chemical products under mild conditions. The method uses high-valent transition metals, which offers better control over reactivity and reduces side reactions.
Researchers at Nagoya University identified a mosaic skin disease caused by sperm cell transmission of keratin mutation. The mutation was found to be identical in the affected daughter and her father, confirming germline transmission. Genetic counseling is crucial for predicting disease risk in future children.
Researchers at Nagoya University found that people eat more and rate food as tasting better when eating with a mirror, not just another person. The study suggests a possible approach to improving the appeal of food for older people who frequently eat alone.
Researchers at Nagoya University identified Dmt as a fruit fly protein related to sororin that is crucial for sister chromatid cohesion. The study shows that Dmt localizes to the joining point of chromatin and requires interactions with cohesin.
Researchers at Nagoya University have developed a highly efficient catalyst that can break down even the toughest amide bonds in plastics under mild conditions. This breakthrough has significant implications for the recovery of materials from waste plastics and could help realize an anthropogenic chemical carbon cycle.
Nagoya University researchers have created whisker-like crystals composed of tantalum, silicon, and tellurium, which produce high thermoelectric powers over a wide temperature range. The crystals' unique one-dimensional electronic structures enable low electrical resistivity and improved cooling performance.
A team of researchers mimics the vibrant color of Stellar's jay bird plumage and demonstrates a new way to control light interaction with materials. The development could lead to engineering new materials for solar cells, camouflage, and more.
Researchers at Nagoya University and their colleagues studied historical seismic events to shed light on the mechanisms behind earthquakes at a plate boundary. They found that stronger earthquakes involved ruptures at different sites, providing new insights into risk prediction tools for assessing earthquake likelihood and intensity.
Researchers have identified a novel pathway that allows green algae to reset its circadian clock when exposed to red or violet light. The study reveals the existence of at least two different pathways in algae that sense and respond to different colors of light.
Research at Nagoya University reveals that phloem-specific polypeptides act as mobile descending shoot-to-root signals in response to nitrogen status, triggering compensatory nitrogen uptake by roots. This sophisticated signaling system enables plants to maximize nutrient efficiency and improve fertilizer application.
Researchers have created a pioneering nanobiodevice that can isolate cancer biomarkers quickly with high resolution. The device separates microRNA from DNA/RNA mixtures in under 100ms, promising faster and more reliable isolation of microRNA for cancer detection.
A Nagoya University-led international research team has identified genes controlling the development of enlarged mandibles in stag beetles, a key factor in insect diversity. The study found that genes such as dac, aristaless, and homothorax play important roles in mandible development.
Researchers at Nagoya University identified two peptides, CIF1 and CIF2, that regulate Casparian strip assembly in response to developmental and environmental cues. The study found that these peptides are necessary for the formation and maintenance of the barrier, which helps maintain ion homeostasis and adapt to harsh soil conditions.
Nagoya University researchers have discovered a link between RNA binding proteins FUS and SFPQ and the development of frontotemporal lobar degeneration, a type of dementia that starts in middle age. The study suggests that rebalancing the tau protein ratio may prevent FTLD-like phenotypes.
Nagoya University researchers have developed a new class of composite materials with negative thermal expansion, offering potential solutions for industrial applications. The reduced ruthenate ceramic material shrinks by up to 6.7% when heated, making it more than double the current record-holding material.
Researchers have identified a new type of solar event and dated it to 5480 BC using carbon-14 levels in tree rings. The team proposes causes for the event, extending knowledge of the sun's behavior and its effects on Earth. The study provides new insights into the sun's activity during the mid-Holocene period.
Researchers at Nagoya University have uncovered a novel brain circuit for hunger responses during starvation, revealing the role of neuropeptide Y signals in controlling heat production by brown adipose tissue. The study found that inhibitory GABAergic inputs from medullary reticular neurons inhibit BAT thermogenesis.
Researchers at Nagoya University have synthesized stable antiaromatic nickel norcorroles and investigated their interactions, revealing face-to-face interactions that form a triple-decker structure with aromatic characteristics. The resulting materials exhibit nonlinear optical properties and potential applications in optoelectronics.
Researchers at Nagoya University developed a cold plasma-activated Ringer's solution that exhibits anti-tumor effects, attributed to the lactate component. The solution triggers cell death through increased intracellular hydrogen peroxide levels, suggesting a potential specific tumor therapy.
Researchers developed a novel approach to strengthen polymer gels by modifying the length of polymer threads per molecular beads, increasing fracture resistance and strain strength. The technique enables fabrication of polymer gels with desired mechanical properties.
Researchers aim to create 'sponge-like' materials for safe capture, storage, and release of essential small molecules. The project seeks to develop innovative nanoporous materials for efficient gas separation, storage, and release.
A study by Nagoya University found that collapse of the MAM is a common pathological hallmark in SOD1- and SIGMAR1-linked ALS. This disruption leads to Ca2+ dysregulation, exacerbating neurodegeneration. The researchers suggest targeting MAM disruption for future therapeutics.
A Nagoya University research team used a new image processing tool to confirm that humans have evolved specifically to detect snakes. Humans were able to identify snakes in much blurrier images than other harmless animals, suggesting heightened visual awareness of snakes.
Nagoya University researchers have developed a strategy to obtain polymer brushes on surfaces using diblock copolymers. The approach allows for easy control of brush thickness and structure by changing the number and/or type of units in the diblock copolymer.
Researchers at Nagoya University have identified a novel potential target of the type 2 diabetes drug metformin: the ion exchanger protein NHX-5. In nematode worms and fruit flies, metformin targets NHX-5 to disrupt autophagy and related subcellular processes.
Researchers studied nerve regeneration in roundworms and discovered a signaling pathway that induces nerves to regenerate. This pathway is also involved in clearing dying cells, suggesting a potential target for improving human recovery from nerve injury.
Researchers at Nagoya University developed a micro-sized device that can detect the IDH1-R132H mutation in glioma tumors, enabling real-time identification of tumor margins during surgery. The device takes less than 15 minutes to produce results and requires only small sample sizes.
A team of Japanese researchers has elucidated the structure of the bacterial flagellar motor protein MotA from a hot spring bacterium. The study reveals that MotA forms a tetramer complex with a unique shape differing from previous predictions, and can exist independently of another transmembrane protein MotB.
Researchers at Nagoya University have created a label-free method for detecting real-time DNA amplification based on refractive index changes in diffracted light. This technique is highly sensitive and can quantify DNA concentrations from 1 fM to 1 pM, outperforming existing fluorescence-based detection systems.
An international research team identified a signal peptide required for awn elongation in wild rice and found its dysfunction in cultivated Asian rice. The study suggests human selection pressure led to the loss of this peptide's function, resulting in awnlessness.
Researchers developed a new index to predict if extinct mammalian species lived exclusively in water, were occasionally on land, or were fully land-based. The index uses rib strength measurement to differentiate between habitats and was applied to four extinct species with partially or completely aquatic lifestyles.
Researchers found that mice lacking orexin neurons are more sensitive to pain, while activating these neurons decreases pain-related behaviors. This suggests a link between wakefulness and the inability to feel pain.
A study by Nagoya University researchers reveals high levels of genetic heterogeneity and DNA instability in schizophrenia patients, suggesting a possible link between copy number variations (CNVs) on chromosomes 1, 15, 16, and 22 and disease mechanisms.
Researchers found domestic goats in the Southern Caucasus match with wild goats from the Fertile Crescent, suggesting introduction of already-domesticated goats. Genetic sequencing reveals sudden cultural changes and agriculture adoption around 7,500-8,000 years ago.
A research group discovered a Great Platform in San Andrés, El Salvador, which indicates the southeastern Maya people's ability to recover and rebuild after the devastating Ilopango eruption. The platform, built with different stone types, suggests an external cultural connection and cooperative relations beyond cultural boundaries.
A new simulation code was developed to accurately predict coronal mass ejections (CMEs) and their impact on space weather. The model successfully validated using observational data from the 2003 Halloween CME events, enabling accurate predictions of magnetic fields and arrival times.
Scientists discovered that scale-eating cichlids gradually acquire lateralized behavior as they learn to eat scales from one side of their mouth. The study found a correlation between mouth asymmetry and the direction of attack on prey, with older fish having more skewed mouths that ate more scales.
Researchers at Nagoya University have uncovered a dopamine signaling pathway that controls cocaine reward in mice. The study found that activation of the Rap1 pathway increases neuronal excitability and sensitivity to cocaine reward.
Researchers at Nagoya University developed a novel immunotherapy using genetically engineered T cells that target podoplanin, a key protein associated with GBM progression. This treatment successfully arrested tumor growth in 60% of mice and demonstrated promise for treating patients with relapsed or resistant tumors.
Scientists at Nagoya University have made a breakthrough in synthesizing cyanohydrins, useful molecules that are precursors to carboxylic acids and amino acids. The new method uses a chiral catalyst to produce optically active cyanohydrins with high yield and efficiency.