Scientists from Osaka University have created a new class of materials, called chiral bifacial indacenodithiophene-based π-conjugated polymers, that can selectively interact with electrical currents in different polarities. These films exhibit strong spin polarization, making them promising for applications in spintronics and clean ene...
Researchers from Osaka University have synthesized a new molecule that increases the power conversion efficiency of organic solar cells. The molecule's design reduces exciton binding energy, making it easier to convert sunlight into current. This breakthrough paves the way for high-performance and large-scale photovoltaic applications.
A team of researchers from Osaka University has pinpointed the B cells responsible for boosting COVID-19 immunity after vaccination. They found that activated atypical B cells are the main responders to mRNA vaccines, providing a new way to assess vaccine response and underlying biology.
A research group from Osaka University has developed a novel green chemistry method to synthesize sulfonyl fluorides efficiently and with minimal environmental impact. This process uses easily accessible raw materials, thiols and disulfides, and produces only non-toxic sodium and potassium salts as byproducts.
A groundbreaking study published in Psychiatry Research Communications reveals a critical link between melatonin secretion and the severity of ADHD symptoms in children. Genetic variations affecting melatonin production may play a significant role in the development and exacerbation of ADHD symptoms.
A team of scientists from Osaka University has created a polarisation multiplexer on a substrateless silicon base, which doubles the data capacity under the same bandwidth with lower data loss than existing devices. This innovation paves the way for more robust and reliable high-speed wireless networks.
Researchers at Osaka University discovered that a protein sensitive to electrical signals plays a key role in promoting proper sperm development and maturation. The study's findings suggest that the protein, known as VSP, converts electrical signals into chemical signals necessary for sperm maturation.
A pioneering Japanese study found substantial improvements in mental well-being among gamers, with Nintendo Switch ownership leading to 0.60 standard deviations of improvement. The research challenges negative perceptions and highlights the need for a nuanced approach to studying digital media's effects on health.
Researchers from Osaka University have developed a humanized antibody that blocks the DKK1–CKAP4 pathway, stimulating cancer cell growth. The new anti-CKAP4 antibody suppressed tumor formation in mice with both human and mouse tumors, as well as modulating anti-tumor immune reactions.
Researchers at Osaka University have created molecular wires with periodic twists that increase electrical conductivity. The discovery could lead to the development of cheaper and biocompatible electronic devices.
A research group at Osaka University proposes two proactive ethics consultation methods: inter-professional ethics rounds and patient note reviews. These methods aim to improve clinical decision-making by addressing ethical issues in a more proactive manner, leading to better medical care and alleviated moral anguish among medical staff.
The team discovered that the exciton-binding energy of solid materials is affected by how their molecules stack together, known as aggregation. By manipulating molecular aggregation, they found a way to decrease the exciton-binding energy and improve device performance.
A German-Japanese research team developed a polymer inspired by a protein found in plants to selectively remove harmful heavy-metal ions from water. The polymer achieves high specificity and efficiency, making it a promising solution for improving water treatment processes.
Researchers at Osaka University have developed a faster, highly accurate way to measure the temperatures of electronic components using neutrons. The technique, called neutron resonance absorption, can acquire temperature data in just 100 nanoseconds.
A new organic molecule thienyl diketone achieves high-efficiency phosphorescence more than ten times faster than traditional materials. This breakthrough provides design guidelines for developing metal-free organic phosphorescent materials, promising significant advancements in various applications.
Researchers at Osaka University have developed molecules that can correct improper splicing of a vital tumor suppressor gene in neuroendocrine cancers. The study demonstrates that these splice-switching oligonucleotides can significantly reduce viable cancer cells and tumor size in mice, suggesting a novel therapeutic approach for intr...
A research team from Osaka University identified a key osteoporosis-related gene, Men1, and developed a new animal model of the disease. The study found that inactivation of Men1 led to cellular senescence in osteoblasts, reducing bone formation activity and increasing bone resorption.
Researchers at Osaka University have developed systematically designed molecules that absorb near-infrared light but not visible light, paving the way for new applications in electronics. The new compounds show promise in areas such as solar cells, transistors, chemotherapy, and photodetectors.
A study published in Science Advances reveals that germ cells drive sex-dependent lifespan differences in vertebrate animals. Removing these cells led to similar lifespans in males and females of the turquoise killifish species. Vitamin D was also discovered to have a role in improving longevity, with supplementation extending life spans.
A research study at Osaka University found that feeling understood by others significantly reduces prejudice, leading to more positive intergroup relationships. The study suggests that learning local languages and communicating understanding can help reduce discrimination issues.
A study published in Applied Physics Letters reveals that decreasing carbon concentration can increase the amount of light emitted from GaN crystals. The researchers found a threshold concentration above which carbon atoms become a significant factor in dissipating energy, leading to improved internal quantum efficiency.
Researchers found high GDF15 levels in steatotic liver patients are associated with an increased risk of liver cancer. Combining blood GDF15 levels with liver stiffness indicators can efficiently identify patients at high risk of developing liver cancer and poor outcomes.
Researchers from Osaka University developed a mobile mixed reality (MR) system for intuitive flooding forecasts, allowing urban populations to view dynamic flood forecasts on their mobile devices. The system enables widespread participation in MR visualizations, improving community preparedness and response.
Researchers at Osaka University developed an innovative positioning system for drone-based mixed reality applications, enabling accurate alignment between real and virtual worlds. This development will lead to versatile drone-based MR applications in architecture, engineering, and construction.
A team from Osaka University used electron microscopy and computer simulations to study the kinetics of microstructure formation in Fe3Al, leading to a deeper understanding of its superelastic properties. The findings could provide insights for heat treatments and applications in construction and healthcare industries.
A team from Osaka University demonstrates greater control of ion passage through a nanopore membrane by applying a voltage to a gate electrode. This leads to a six-fold increase in osmotic energy efficiency and a power density of 15 W/m^2, enabling the potential for scaling up the technology.
A new alpha-ray therapeutic agent ([At-211] PSMA-5) has been developed to target prostate-specific membrane antigen (PSMA) in refractory prostate cancer patients. The therapy has shown efficacy in animal models and is now being tested in a first-in-human clinical trial.
A study published in Nature Communications found that sharp-wave ripples in the hippocampus are associated with vivid, imaginative self-generated thoughts and less pleasurable states. This link may have implications for understanding conditions such as autism, attention deficit disorder, and happiness/well-being.
A new study published in JAMA Network Open reveals that upward social mobility significantly lowers the risk of dementia. The research, led by Osaka University researchers, analyzed data from 9,186 participants aged 65 and over, finding that individuals who experienced upward transitions had a notably lower risk of dementia incidence c...
Researchers from Osaka University found that Csk inhibits germinal center B cell signaling, decreasing reactive oxygen species production and promoting affinity maturation. This study reveals the crucial role of Csk tyrosine kinase in regulating B cell development.
A team at Osaka University uses novel RNA sequencing techniques to reveal the molecular basis for sexual dimorphism in Daphnia, a species of water flea that can change its form and behavior despite being genetically identical. The study identifies genes that switch which isoforms are expressed in a sex-dependent manner.
A team of researchers from Osaka University used machine learning to identify a highly effective boron-based catalyst for chemical transformations of amino acids and peptides. The new catalyst generates only water as a coproduct and promotes high-yield reactions with minimal environmental impact. By leveraging computational methods, th...
A study from Osaka University found that all five strains of C. butyricum causing bacteremia were derived from probiotics, highlighting the risk of serious adverse events from probiotic use, especially in hospitalized patients. This research underscores the need for judicious prescription practices.
Researchers from Osaka University found that influenza-associated brain disorders may be caused by the virus entering the brain and producing proteins. Antivirals blocking protein production are unlikely to be effective, but those targeting transcription and translation may offer hope for treatment.
Researchers at Osaka University discovered that certain 'sentinel macrophages' near the liver's entrance protect it against intestinal bacteria and related substances. Isoallo-lithocholic acid triggers their activation, highlighting a potential target for preventing liver inflammation and metabolic dysfunction-associated steatohepatitis.
A study by Osaka University researchers found that mask-wearing behavior depends on the interplay of contextual changes and social norms. The results showed no significant relationship between system justification motivation and individual mask-wearing rates before or after the relaxation of governmental recommendations in March 2023.
Researchers from Osaka University have developed a new approach for super-resolution microscopy that can observe dense microstructures inside cells with excellent sharpness. By selecting only a desired plane to image using thin 'light sheet' illumination, they were able to achieve background-free super-resolution imaging.
Scientists from Osaka University create borane molecules that exhibit red-shifted light emission upon binding to fluoride, enabling versatile materials for electronic display and chemical sensing applications. The researchers also achieve fine-tuning of the color of light emission by adjusting the quantity of added fluoride.
Researchers from Osaka University have discovered a way to deliver antisense oligonucleotides to their targets inside cancer cells by opening specific calcium permeable channels. The new compound, L687, promotes efficient uptake of ASO into cancer cells, suppressing target gene activity and enhancing ASO efficacy.
Tetracycline antibiotics have been found to enhance the antitumor activity of T lymphocytes by targeting galactin-1, an immunosuppressive protein produced by cancer cells. This breakthrough discovery may lead to the development of new drugs that target different immune pathways and benefit patients with cancer.
A new study found that access to genomic testing for cancer is limited by factors such as test availability, patient information, and insurance coverage in both Japan and Switzerland. Despite universal insurance coverage, barriers persist due to differences in hospital accessibility, language barriers, and varying levels of reimbursement.
Researchers used operando spectroscopy to study the oxygen evolution reaction in iridium oxide catalysts. The team found that binding of reaction intermediates to the electrode was controlled by long-range interactions between the intermediates and the solution, which depended on pH.
Researchers from Osaka University found that exposure to environmental carcinogens and psychological distress decrease emotional wellbeing in Japanese people, with a 0.0064-year decrease for radon and 0.97 years for psychological distress. The study suggests that reducing exposure to these chemicals can help promote longer, happier lives.
A study published in Critical Care identified eight different trauma phenotypes associated with lower in-hospital mortality when treated with tranexamic acid. The researchers used a machine learning model to analyze data from over 50,000 patients and found subgroups of patients who received no benefit from treatment.
A study by Osaka University found that thinking about sustainability from the perspective of imaginary future generations yields new insights into technological innovation and societal trends. Participants in workshops ranked indicators differently after adopting this perspective, perceiving technology's feasibility more accurately.
Conventional projection mapping systems work only in dark environments due to surrounding illumination. Researchers from Osaka University developed a method to control both image and illumination, allowing for realistic projections in bright environments. This technology enables interactive displays with multiple viewers under natural ...
Researchers from Osaka University have developed a combined microscopy technique that captures the nanoscale behavior of azo-polymer films triggered by laser light. This allows for real-time observation with high spatiotemporal resolution, shedding light on the mechanism of light-driven deformation in these materials.
A team from Osaka University's SANKEN Institute used the shortcuts to adiabaticity (STA) method to speed-up the adiabatic evolution of spin qubits. The spin flip fidelity after pulse optimization reached up to 97.8%. This method may be useful for fast and high-fidelity quantum control in other systems.
A study by Osaka University researchers found that Japanese liberals are more sensitive to collective ownership threats than conservatives. The study suggests that this sensitivity may deter countries from engaging in activities that infringe on the territorial integrity of others.
Researchers from Osaka University found that (R)-ketamine can improve social impairments in mice with depression by restoring neuronal activity in the anterior insular cortex. The study suggests that (R)-ketamine may be a more effective treatment for social cognition than its counterpart (S)-ketamine.