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Shanghai Jiao Tong University Journal Center


Application of spatial and single-cell omics in tumor immunotherapy biomarkers

Emerging technologies like spatial and single-cell omics improve our understanding of tumor biology and facilitate personalized cancer immunotherapies. These approaches enable researchers to identify novel biomarkers that predict therapeutic responses and monitor disease progression in real-time, ultimately improving patient outcomes.

SourceShanghai Jiao Tong University Journal Center·JournalLabMed Discovery·TypeObservational study·DateAug 3, 2025

Multifunctional ANF/MXene-enhanced hydrogels for flexible EMI shielding and wearable sensing applications

Researchers developed a multifunctional hydrogel reinforced with ANFs and MXene, achieving outstanding EMI shielding and wearable sensing performance. The innovative design balances electrical conductivity and effective absorption, addressing long-standing challenges in flexible electronics.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 31, 2025

Recombinant fusion ESAT6-CFP10 immunogen as a skin test reagent for tuberculosis diagnosis in children and adolescents: An open-label, randomized, multicenter phase III trial

A new skin test reagent using the recombinant ESAT6-CFP10 fusion protein has been developed to overcome limitations of existing tests. The C-TST, a phase III clinical trial, demonstrated high sensitivity (91.2%) and specificity (69.7%) for TB diagnosis in children and adolescents.

SourceShanghai Jiao Tong University Journal Center·JournalLabMed Discovery·TypeExperimental study·DateJul 31, 2025

MXene‑Ti3C2Tx‑based neuromorphic computing: physical mechanisms, performance enhancement, and cutting‑edge computing

This review highlights the potential of MXene-Ti3C2Tx as a universal platform for neuromorphic devices, offering sub-femtojoule synaptic events and nanosecond response times. The material enables flexible, multimodal, and biocompatible systems that classical silicon cannot match.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 31, 2025

Modified near-infrared annealing enabled rapid and homogeneous crystallization of perovskite films for efficient solar modules

Researchers have developed a modified near-infrared annealing process that turns blade-coated perovskite films into record-performing solar modules in just 20 seconds. The process slashes processing time by 30 times and halves energy use while delivering superior film quality.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 31, 2025

Phase-regulated FACsPbI3 films via triple-source thermal co-evaporation enable high-efficiency near-infrared perovskite LEDs

Researchers introduced a novel approach for fabricating high-performance near-infrared perovskite light-emitting diodes (NIR-PeLEDs) using triple-source thermal co-evaporation. This strategy directly forms the black-phase α-FACsPbI3 perovskite, overcoming phase instability and surface roughness issues.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 30, 2025

Clinical potential of undercarboxylated osteocalcin in metabolic and neurodegenerative diseases: From biomarker to therapeutic target

Research examines undercarboxylated osteocalcin's impact on diabetes, osteoporosis, Alzheimer's disease, and other conditions like NAFLD and depression. Glu-OCN's influence on glucose homeostasis, lipid metabolism, and cholesterol metabolism is discussed.

SourceShanghai Jiao Tong University Journal Center·JournalLabMed Discovery·TypeObservational study·DateJul 30, 2025

Chemical fermentation-induced porous bio-carbon with embedded Ni–Fe alloy for ultra-efficient oxygen evolution electrocatalysis

Researchers introduce a novel electrocatalyst design strategy using chemical fermentation, creating a multilevel porous carbon architecture embedded with Ni–Fe alloy nanoparticles. This approach achieves ultra-efficient oxygen evolution reaction performance, with a record-low overpotential of 165 mV at 10 mA cm−2.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 30, 2025

A pilot cohort study of a microfluidic-based point-of-care bilirubin measurement system

A pilot cohort study assesses the efficacy of a microfluidic-based point-of-care bilirubin measurement system in detecting bilirubin levels with high accuracy, comparable to standard clinical laboratory methods. The device's miniaturized optical sensing module and microfluidic test cartridge enable scalable adoption and portability.

SourceShanghai Jiao Tong University Journal Center·JournalLabMed Discovery·TypeNews article·DateJul 30, 2025

Critical bimetallic phosphide layer enables fast electron transfer and extra energy supply for flexible quasi‑solid‑state zinc batteries

Researchers have developed a critical bimetallic phosphide layer that simultaneously accelerates electron transfer and delivers extra energy in nickel-zinc batteries. The new design enables fast-charging devices with unmatched energy/power density and mechanical flexibility, paving the way for next-generation energy-storage systems.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 29, 2025

Binding af nity and structural dynamics of amygdalin-HER2 interactions: An investigation for breast cancer therapy

Breast cancer is a heterogeneous disease classified into subtypes based on hormone receptor presence, with HER2 being a critical factor. Amygdalin, a natural compound, has shown promise in targeting HER2-positive breast cancer cells by modulating apoptotic regulators and reducing tumor progression.

SourceShanghai Jiao Tong University Journal Center·JournalLabMed Discovery·TypeNews article·DateJul 29, 2025

Improved core manifestations of autism following supplementation with vitamin D3-loaded nanoemulsion

Supplementation with vitamin D3-loaded nanoemulsion has been shown to improve core manifestations of autism in children, including adaptive behavior and language performance. The study investigated the effects of vitamin D3-loaded nanoemulsion on autistic children's adaptive behavior and language skills, revealing a beneficial impact o...

SourceShanghai Jiao Tong University Journal Center·JournalLabMed Discovery·TypeNews article·DateJul 29, 2025

Enhanced regional electric potential difference of graphdiyne through asymmetric substitution strategy boosts Li+ migration in composite polymer solid‑state electrolyte

Researchers developed a new composite polymer solid-state electrolyte that achieves record-high performance, enabling safe and energy-dense all-solid-state lithium batteries. The OGDY/PEO electrolyte boosts Li+ migration, suppresses dendrites and maintains film flexibility.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 29, 2025

Highly thermal conductive and electromagnetic shielding polymer nanocomposites from waste masks

Researchers have developed a novel polymer nanocomposite from COVID-19 waste masks, achieving record-high thermal conductivity and electromagnetic shielding. The closed-loop upcycling strategy reduces environmental impact and cost, paving the way for sustainable electronics and circular economy applications.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 24, 2025

Breaking performance limits of Zn anodes in aqueous batteries by tailoring anion and cation additives

Researchers created a highly textured Zn surface by introducing benzyltriethylammonium chloride (TEBAC) and selectively removing its counter-ion, achieving unprecedented stability and durability. The optimized electrolyte delivered 9000 hours of dendrite-free cycling in coin cells.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 22, 2025

Reducing the voc loss of hole transport layer-free carbon-based perovskite solar cells via dual interfacial passivation

Researchers introduce a simple protocol to simultaneously passivate defects at the SnO2/perovskite bottom interface and the perovskite/carbon top interface of hole transport layer-free carbon-electrode perovskite solar cells. The result is a champion device delivering high power conversion efficiency and ambient durability.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 18, 2025

Highest solar-to-hydrogen conversion efficiency in Cu2ZnSnS4 photocathodes and its directly unbiased solar seawater splitting

Researchers have introduced a new method to overcome defect limitations and enhance the performance of CZTS photocathodes, delivering a record half-cell solar-to-hydrogen efficiency of 9.91% in natural seawater. The device also sustains high photocurrent and exhibits corrosion resistance against chloride ions and dissolved oxygen.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 17, 2025

LabMed Discovery Support

The Shanghai Jiao Tong University Medical-Engineering Interdisciplinary Journal Alliance aims to bridge medicine and engineering research through scholarly publishing. The partnership seeks to accelerate translational research in precision medicine and biomedical engineering, increasing global visibility for China's 'Double First-Class...

Induction effect of fluorine-grafted polymer-based electrolytes for high-performance lithium metal batteries

A fluorine-grafted quasi-solid composite electrolyte boosts ionic conductivity while sculpting a self-armoring LiF-rich interphase, enabling ultra-stable cycling. The electrolyte sustains symmetric Li||Li cells for over 4,000 hours and drives Ni-rich NCM622 full cells to retain nearly 100% capacity after 350 cycles.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 15, 2025

Single‑point linkage engineering in conjugated phthalocyanine‑based covalent organic frameworks for electrochemical CO2 reduction

Researchers have developed a new approach using nickel phthalocyanine-based covalent organic frameworks for electrochemical CO2 reduction. The study, led by Professor Zheng Meng, presents highly efficient CO2 conversion and innovative design mechanisms.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 10, 2025

Spatial and single-cell omics propel precision biomarker discovery in tumor immunotherapy, review finds

A new review leverages cutting-edge spatial transcriptomics and single-cell omics to identify robust predictive biomarkers for tumor immunotherapy. Representative case studies highlight the potential of spatially resolved markers to guide immunotherapy decisions and predict irAE risk.

SourceShanghai Jiao Tong University Journal Center·JournalLabMed Discovery·TypeNews article·DateJul 10, 2025

Improved core manifestations and language skills in autism following new vitamin D3 nanoemulsion supplement

Researchers investigated the effects of vitamin D3-loaded nanoemulsion on adaptive behavior and language performance in children with ASD. The study found improved core manifestations and receptive and expressive language abilities, suggesting a potential therapeutic benefit for children with ASD.

SourceShanghai Jiao Tong University Journal Center·JournalLabMed Discovery·TypeNews article·DateJul 9, 2025

A mechanically robust in-situ solidified polymer electrolyte for SiOx-based anodes: A dragonfly wing-inspired design for high-energy lithium batteries

Researchers developed a mechanically robust in-situ solidified polymer electrolyte inspired by the microstructure of dragonfly wings, offering superior mechanical properties and electrochemical performance. The innovative design and mechanisms may lead to significant advancements in SiOx-based anodes for lithium-ion batteries.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 9, 2025

In situ polymerization in COF boosts li‐ion conduction in solid polymer electrolytes for li metal batteries: A new approach to enhance ion transport efficiecyn

A new approach to improve lithium-ion conduction in solid polymer electrolytes is presented through in situ polymerization within a covalent organic framework, boosting the performance of lithium metal batteries. This innovative design enhances ion transport efficiency and paves the way for high-performance lithium metal batteries.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 7, 2025

Indium-MOF as multifunctional promoter for fluoropolymer electrolytes in all-solid-state lithium metal batteries: A breakthrough in electrochemical stability and ionic conductivity

Researchers developed indium-based metal–organic frameworks (In-MOFs) to improve poly(vinylidene fluoride–hexafluoropropylene) electrolyte performance in all-solid-state lithium metal batteries. The In-MOFs enhance electrochemical stability and ionic conductivity, leading to significant performance improvements.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 7, 2025

Self-assembled supramolecular interfaces enable stable and high-rate zinc anodes for aqueous hybrid supercapacitors

Researchers develop a scalable strategy to improve zinc anode cycling stability and reaction kinetics using self-assembled supramolecular interfaces. The sulfobutyl-grafted β-cyclodextrin additive enhances Zn2+ transport and deposition uniformity, suppressing corrosion and dendrite growth.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 4, 2025

Blood Type A linked to higher risk of hypertension and diabetes in the Chakhesang tribe of Nagaland

Research found a strong association between blood type A and increased risk of hypertension and diabetes among the Chakhesang Naga tribe. Genetic analysis suggests a potential genetic predisposition, highlighting the importance of considering genetic and environmental factors in health outcomes.

SourceShanghai Jiao Tong University Journal Center·JournalLabMed Discovery·TypeObservational study·DateJul 3, 2025

Universal amplification-free RNA detection with CRISPR-Cas10 and graphene field-effect transistors

Researchers have developed a novel biosensing platform combining CRISPR-Cas10 with graphene field-effect transistors (GFETs) for amplification-free RNA and microRNA detection. The approach achieves detection limits at the attomolar level, making it suitable for health monitoring and disease diagnosis.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 2, 2025

Buried interface regulation with TbCl3 for highly-efficient all-inorganic perovskite/silicon tandem solar cells

Researchers developed highly efficient all-inorganic perovskite/silicon tandem solar cells using a novel TbCl3 doping strategy. This innovation integrates seamlessly with silicon solar cells, achieving remarkable efficiencies and contributing to sustainable energy future.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 2, 2025

Snake-inspired soft robot with multimodal locomotion and grasping capabilities

Researchers developed a snake-inspired soft robot (ICSBot) that leverages diverse locomotion modes to navigate complex environments and handle objects with high flexibility. The ICSBot's design offers new possibilities for creating adaptive robotic systems inspired by nature, enabling enhanced performance and autonomy.

SourceShanghai Jiao Tong University Journal Center·JournalNano-Micro Letters·TypeExperimental study·DateJul 2, 2025