A new project aims to investigate the genetic influences on behaviors, producing polygenic risk scores for individualized interventions. However, experts express concerns about the risks of misusing this research to justify social inequality.
Emerging norms in engaged translational genomics research raise substantial ethical concerns. Simplified Spanish-language consent materials require cultural congruence, while participant benefits in HIV prevention research highlight potential direct and indirect benefits for stigmatized populations.
The book explores the social and ethical implications of gene editing on human germline cells, including its impact on relationships between parents and children, health, normalcy, and well-being. Leading thinkers weigh in on the potential risks and benefits of this revolutionary technology.
A study on learning health organizations highlights the paradox of bystander ethics, where researchers must navigate ethical principles with quality improvement research. The authors propose a workaround to address this challenge, but critics argue it is inadequate.
A multistakeholder study proposes six policy options for governing heritable genome editing, including proactive regulation and broad public engagement. Meanwhile, gynecological surgery reform is urged due to declining OB-GYN skills and lack of transparency, putting patient safety at risk.
A new special report by The Hastings Center examines the psychosocial impacts of genetic information, highlighting both potential harms and limitations. Studies suggest that genetic testing can have negative effects on individuals and families, particularly in contexts where stigmatization or anxiety is heightened.
The Hastings Center is conducting groundbreaking research on dementia and end-of-life choices, examining the ethical implications of living with dementia. The study aims to identify areas where further research or policymaking is needed to improve the experiences of those affected by dementia.
A study explores how parents make decisions about enrolling their critically ill children in research, finding that low-risk studies with potential benefits to future children are more likely to be enrolled. Another article highlights the importance of considering inclusion benefits in ethics committee assessments of research studies.
The federal right-to-try law has been criticized for undermining the FDA's role in monitoring drug safety and efficacy, potentially creating a loophole for pharmaceutical companies to sell unapproved drugs. In contrast, citizen science and gamification are changing the way research is conducted, with nonprofessional volunteers contribu...
Researchers propose anticipatory waivers of consent for pediatric biobanking, allowing for efficient use of samples from minors. The authors also examine the inadequate response to the US Public Health Service's unethical experiments in Guatemala.
Patient-centered care has merged with the concept of patients as consumers, potentially causing harm. The consumer metaphor fails to account for health care's distinct characteristics, such as lack of information and time to select options. Instead, costs are driven by physician compensation and government failure to negotiate prices.
The article explores the intersection of social media, emerging technologies, and medical ethics. Bioethicists discuss various issues such as bias in AI systems and patient relationships affected by social networking sites. The authors also provide recommendations for addressing ethical challenges in these areas.
The inaugural issue of Ethics & Human Research explores new challenges in US human subjects research, including the impact of single-IRB mandates and genome editing. The journal also examines the need for local knowledge in multisite studies and highlights the difficulties countries face in adhering to international ethical standards w...
A new special report explores the definition of death, including the controversy over brain death and its implications for organ transplantation. Leading experts discuss areas of ongoing debate, such as whether brain-dead organ donors are truly dead.
A proposed taxonomy categorizes conscience protections based on state or private actors, as well as provider conduct. Bioethicists must shape AI and machine learning to prevent moral pitfalls, including exacerbating human biases and weakening patient confidentiality.
The report examines how bioethics can better reflect the needs of an aging society. Key findings include the impact of economic insecurity on older adults, inadequate housing solutions, and socioeconomic disparities affecting communities.
The Hastings Center report explores advanced care directives for dementia patients, childhood obesity, and patient demands for specific healthcare providers or racial/ethnic backgrounds. Competent individuals should have control over life-sustaining treatments, while environmental factors contribute to childhood obesity.
A new report recommends that targeted genomic sequencing be used to diagnose sick newborns, but genome-wide sequencing of all newborns should not be pursued. The report also advises against direct-to-consumer genetic testing for newborns due to potential anxiety and lack of adequate follow-up.
The article discusses the ethical implications of genetic testing and the duty to warn family members of hereditary disease risks. Experts argue that patients have a moral obligation to share their genetic information with relatives, citing the principle of rescue as a framework for decision-making.
Experts argue that scientific progress can generate harm, while researchers propose a revised standard for disclosing incidental findings. Bioethicist Daniel Callahan also suggests delaying technological innovation to consider its consequences. Additionally, experts like Sean Philpott-Jones advocate for concrete policy measures on gun ...
The Hastings Center Report has published a new article examining the ethics of rationing healthcare resources through inconvenience. The authors argue that under certain conditions, this approach can be ethical and even preferable to direct rationing. Meanwhile, another author highlights the potential downsides of this practice, includ...
A new report from The Hastings Center proposes a policy analysis framework that aligns governance of emerging technologies with the public's values. The framework incorporates a refined understanding of precaution and emphasizes transparency in value judgments. It also explores new institutions for coordination and public engagement.
The article examines the persistence of continuous electronic fetal monitoring as a standard of care, despite evidence that it increases risks. It also discusses the lack of mechanisms for ensuring medical professionals stay current with best practices and the role of malpractice law in setting boundaries on acceptable interventions.
The report examines how financial constraints, clinical expectations, and societal pressures impact reproductive autonomy. It also delves into the 'criminalization of pregnancy' causing racial disparities in reproductive autonomy.
The Hastings Center Report examines ethical dilemmas in global health, including resource sensitivity, physician-assisted death and parental authority. The case for providing cheaper, less effective treatments to promote health and realize ethical values is presented.
The approved gene therapy Kymriah offers hope for children and young adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia. However, its high cost and limited accessibility pose significant challenges for policy-makers and patients alike.
The Hastings Center recommends adopting reimbursement policies and guidelines to support clinicians in providing informed consent for prenatal genetic testing. The authors also suggest funding education and counseling approaches to help patients make decisions about testing.
The article explores de-extinction efforts, highlighting potential ecological benefits and challenges. Experts debate whether de-extinction initiatives aid or hinder conservation efforts, with concerns about habitat destruction and climate change.
The Precision Medicine Initiative raises concerns about protecting participant data and balancing health needs across sociocultural groups. Research on life extension also sparks debates over its necessity and potential economic and social impacts.
The Hastings Center Report explores the ethics of opioid treatment agreements, which critics say are ethically suspect. The authors conclude that the purpose of these agreements is to disclose their requirements to patients, promoting mutual decision-making on pain management programs. In contrast, some experts propose replacing agreem...
The Hastings Center Report explores how bioethics can address authoritarian populism and contribute to the rebuilding of civic foundations. A study on prisoners' participation in clinical research found unique influences that may leave them vulnerable to exploitation.
Gene drives have the potential to address persistent problems like eradicating mosquito-borne diseases and conserving endangered species. However, they also pose risks to entire ecosystems, highlighting the need for careful public engagement and regulatory policies.
The ethics of gene editing is being explored in a session at the AAAS annual meeting, examining concerns beyond safety, such as modifying the human germline, parental relationships, and respect for persons with disability. Experts will discuss new technologies and their social and ethical implications.
The Hastings Center Report explores the disagreement between physicians and surrogates on cardiopulmonary resuscitation and palliative sedation. The articles examine policy adopted by Massachusetts General Hospital to support doctors who judged CPR would not benefit a patient, and discuss limitations of surrogate decision-making author...
The Hastings Center Report examines the ethics of crowdfunding for medical care, citing concerns over fraud, misinformation, and health inequities. The article proposes reducing the number of clinical trials to improve their quality and provide evidence-based decision-making.
Conflicts of interest between players and club doctors pose a threat to NFL players' health, according to a new special report. The report proposes changing the structure of medical care for football players to prioritize player-patient loyalty over dual obligations to clubs and players.
A precautionary approach to governing emerging technologies can support scientific research and prevent potential harms. According to an article in Science, targeted measures can identify specific concerns and establish conditions for successful gene drive research.
The Hastings Center Report explores the implications of precision medicine on ethics and society. The article highlights how the term change from 'personalized' to 'precision' medicine brings new ethical and social concerns, including promoting medical paternalism. It also discusses the risks of stigmatizing certain populations and pri...
Studies on nonhuman primates spark debate over ethics of infection challenges, with experts arguing for stricter safeguards to balance human need with animal welfare
The article explores the negative effects of medical industry gifts on physicians, arguing that well-intentioned actions can be perniciously infected by industry presence. It also examines Medicare's new policy on advance planning and its limitations, as well as the quarantine controversy surrounding Ebola nurse Kaci Hickox's case.
The Hastings Center has launched a three-year project to examine the fundamental questions of using gene editing in humans, including its impact on human flourishing and core values. The project aims to develop new scholarship, equips journalists, and prepares teachers to engage with these issues.
The Hastings Center Report explores bioethics' racial dimensions, including medical racism and conscientious care. The article discusses approaches to mitigate the effects of laws that raise moral conflicts, such as abortion regulations in North Carolina. Two 'Other Voices' essays also examine the role of conscience in healthcare.
The article recommends ways to manage value conflicts and promote patient engagement in clinical care, health care organizations, public health, regulation, and among payers. It proposes strategies such as advance community-based participatory research, facilitating patient and community involvement in learning health systems, and gath...
Recent epigenetics research highlights molecular mechanisms influencing gene expression through socioenvironmental factors. Big data raises concerns over immortalized participant data, privacy, and anonymity, prompting recommendations for strengthening ethical consent practices.
The November-December issue of the Hastings Center Report explores the ethics of neural devices, including deep brain stimulation and brain-computer interfaces. The issue also examines the use of e-cigarettes in health care organizations, where controversy surrounds their safety and effectiveness.
The Hastings Center Report explores enhancement debates, including gene editing and emotions. Alberto Giubilini argues that the methodological divide between bioconservatives and bioliberals is less significant than thought. The report also examines genome editing, ecological research ethics, and organ donation conversations.
The Hastings Center special report explores controversies in genetics of intelligence research, recommending ways to avoid classicism and racism. The report concludes that gene variants influencing intelligence involve complex interactions between genes and environment, making it difficult to identify specific genetic variants.
The Hastings Center has received a $1.1 million NIH grant to conduct an ethical analysis of next-generation prenatal genetic tests, informing clinical guidelines and policy recommendations. The project aims to identify principles and values guiding the use of these tests, as well as policies needed to support their ethical use.
Genome researchers should disclose misattributed parentage to parents to respect their autonomy and sense of self. The issue also explores punishing health care providers for treating terrorists, highlighting the need for moral and legal clarity in such situations.
A recent article by Michael K. Gusmano and Frank J. Thompson examines the success of Medicaid's Delivery System Reform Incentive Payment Initiatives (DSRIP), finding mixed evidence on its effectiveness. The authors conclude that while DSRIP has potential, its effectiveness is still unclear.