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Université de Genève


Drugs of abuse: Identifying the addiction circuit

Researchers at UNIGE have pinpointed the brain circuit responsible for addictive behavior in rodents. The study found that a stronger connection between decision-making and reward systems led to compulsive behavior, which could be regulated by artificially increasing or decreasing the activity of this circuit.

SourceUniversité de Genève·JournalNature·DateDec 19, 2018

X chromosome: how genetics becomes egalitarian

Researchers from UNIGE analyzed skin and blood cells from five women, identifying 55 genes that escape inactivation of the second X chromosome. The team found that XIST gene expression is key to inactivation, but also discovered five other genes playing a crucial role in the mechanism.

SourceUniversité de Genève·JournalProceedings of the National Academy of Sciences·DateDec 19, 2018

Inflate cells to observe their inner life

Researchers at the University of Geneva have developed a new technique called Ultrastructure Expansion Microscopy (U-ExM), which allows for the visualization of cellular structures and protein complexes at a nanoscale. This method enables the detection of biochemical modifications and mapping of large intracellular molecular complexes.

SourceUniversité de Genève·JournalNature Methods·DateDec 17, 2018

Being yelled at: Our brain on alert in a flash

A recent study by researchers at the University of Geneva found that our brains quickly differentiate between angry and happy voices, with a faster response time to perceived threats. This enhanced auditory attention enables us to detect potential dangers more effectively, leading to improved survival behavior.

SourceUniversité de Genève·JournalSocial Cognitive and Affective Neuroscience·DateDec 7, 2018

An exoplanet inflated like a balloon

Researchers from UNIGE have detected helium in the atmosphere of an exoplanet, HAT-P-11b, which is swollen like a balloon due to stellar radiation. The discovery was made using the Carmenes spectrograph on a 4-metre telescope, and supported by numerical simulations that track the trajectory of helium atoms.

SourceUniversité de Genève·JournalScience·DateDec 6, 2018

Assessing India's health with a single question

A study by researchers from UNIGE and Calcutta examines the reliability of a self-assessment question for evaluating health status in middle-income countries. The team found that the simple question provided a sound understanding of India's population health, with better variance captured compared to Switzerland.

SourceUniversité de Genève·JournalBMJ Global Health·DateDec 5, 2018

A molecule for fighting muscular paralysis

Researchers at UNIGE have identified tamoxifen, a breast cancer medication, as a potential treatment for myotubular myopathy, a genetic disease that causes muscle paralysis and death before two years of age. The molecule greatly reduces the progression of the disease and boosts life expectancy in animal models by a factor of seven.

SourceUniversité de Genève·JournalNature Communications·DateNov 19, 2018

Emotional intelligence: A new criterion for hiring?

Researchers at UNIGE and UNIBE developed an emotional intelligence test to measure skills in work environments. The test, called the Geneva Emotional Competence Test (GECO), evaluates understanding emotions, recognizing emotions, regulating one's own emotions, and managing other people's emotions.

SourceUniversité de Genève·JournalJournal of Applied Psychology·DateNov 13, 2018

A grape constituent protects against cancer

Scientists at UNIGE discovered that resveratrol, a molecule in grape skin and seeds, can prevent lung cancer in mice treated with a nasal formulation. The study showed a 45% decrease in tumor load and a higher concentration of resveratrol in the lungs after nasal administration.

SourceUniversité de Genève·JournalScientific Reports·DateOct 3, 2018

Stem cells organize themselves into pseudo-embryos

Researchers have developed artificial pseudo-embryos from mouse stem cells that display characteristics of early embryonic development, including the formation of antero-posterior, dorso-ventral, and medio-lateral axes. These structures, called gastruloids, could complement animal embryos in studying mammalian embryonic development.

SourceUniversité de Genève·JournalNature·DateOct 3, 2018

Why the brain struggles to get off the sofa

Researchers at UNIGE found that the brain struggles to counter its natural inclination towards minimizing effort when faced with physical activity. The study, published in Neuropsychologia, suggests that our ancestors' need to conserve resources for survival has become obsolete in modern societies.

SourceUniversité de Genève·JournalNeuropsychologia·DateSep 18, 2018

Resynchronizing neurons to erase schizophrenia

Researchers at UNIGE successfully resynchronized neurons to correct desynchronization in neural networks, suppressing behavioral symptoms associated with schizophrenia. The study, published in Nature Neuroscience, offers promising results for a new therapeutic approach targeting defective inhibitory neurons.

SourceUniversité de Genève·JournalNature Neuroscience·DateSep 17, 2018

How the brain suppresses the act of revenge

A UNIGE team discovered which brain zones are activated in anger and how the brain suppresses the act of revenge. The prefrontal dorsolateral cortex (DLPFC) plays a key role in regulating emotions, with higher activity during provocation phases leading to less punishment against unfair players.

SourceUniversité de Genève·JournalScientific Reports·DateAug 21, 2018

Blindness gene discovered

UNIGE researchers identified a new gene, MARK3, as the cause of a recessive genetic disorder leading to childhood blindness. The discovery enables accurate diagnosis and may lead to personalized treatment options.

SourceUniversité de Genève·JournalHuman Molecular Genetics·DateJul 23, 2018

Ytterbium: The quantum memory of tomorrow

Researchers at UNIGE have discovered ytterbium, a rare earth element that can store and protect quantum information even at high frequencies. The material's properties make it an ideal candidate for future quantum networks, where the aim is to propagate signals over long distances by acting as repeaters.

SourceUniversité de Genève·JournalNature Materials·DateJul 23, 2018

Hunting molecules to find new planets

An international team of astronomers detected molecules on an exoplanet, allowing it to be visualized. The technique reveals the planet's surface composition and temperature, providing new insights into planetary atmospheres. Future spectrographs will enhance this method, enabling more accurate characterization of planets.

SourceUniversité de Genève·JournalAstronomy and Astrophysics·DateJun 18, 2018

Cystitis treatment: Back to the 1950s

A recent study found that one of the most widely prescribed antibiotics does not meet expected success rates, while another is as effective as newer drugs. The study suggests re-evaluating old antibiotics against modern standards to ensure patient well-being and restrict newer antibiotic use.

SourceUniversité de Genève·JournalJAMA·DateMay 14, 2018

How do people die in Switzerland today?

A study by the universities of Zurich and Geneva found significant differences in end-of-life decisions across Switzerland's three linguistic regions. In all regions, deaths were preceded by one or more end-of-life decisions, with a common legislative framework governing life-sustaining treatment and assisted suicide. The involvement o...

SourceUniversité de Genève·JournalBMC Medicine·DateApr 20, 2018

Freeing electrons to better trap them

Researchers at UNIGE and MBI successfully place an electron in a dual state, neither free nor bound, and regulate its electronic structure. They also discover that high-intensity lasers can amplify light, enabling new possibilities for intense laser propagation in gases.

SourceUniversité de Genève·JournalNature Physics·DateApr 16, 2018

Global warming increases the risk of avalanches

UNIGE researchers analyzed tree rings to link global warming to increasing frequency and intensity of avalanches in the Himalayas. The study found that rising temperatures have led to bigger avalanches traveling greater distances, threatening infrastructure development and socio-economic stability in regions like Himachal Pradesh.

SourceUniversité de Genève·JournalProceedings of the National Academy of Sciences·DateMar 14, 2018