Add BrightSurf on Google Email

Universitat Autonoma de Barcelona


Solving the structure of a functional amyloid protein provides new clues to the origin of a rare disease

Researchers at Universitat Autonoma de Barcelona solved the structure of a functional amyloid protein, hnRNPDL-2, which forms stable and non-toxic fibres in humans. The discovery changes the concept of disease origin and treatment, suggesting that molecules stabilising or facilitating fibre formation could be the key to therapy.

SourceUniversitat Autonoma de Barcelona·JournalNature Communications·TypeExperimental study·DateFeb 3, 2023

COVID calculations lead to unexpected solution to long-standing problem in theoretical computer science

A UAB researcher discovered a new definition of Petri nets that reconciles two longstanding mathematical approaches, allowing for the reconciliation of geometric and algebraic semantics. This breakthrough has been used in epidemiological modeling, including COVID-19 research.

SourceUniversitat Autonoma de Barcelona·JournalJournal of the ACM·TypeComputational simulation/modeling·DateJan 27, 2023

Big dynorphin protects neurons from the accumulation of β-amyloid, one of the main triggers of Alzheimer's disease

A study reveals that big dynorphin, an endogenous opioid peptide, protects neurons against β-amyloid accumulation. The research suggests that big dynorphin can hinder the interaction between β-amyloid and form aggregates, promoting a neuroprotective effect.

SourceUniversitat Autonoma de Barcelona·JournalComputational and Structural Biotechnology Journal·TypeExperimental study·DateDec 21, 2022

The Three-dimensional structure of the mammalian genome, more diverse than ever seen before

A study by Universitat Autònoma de Barcelona reveals the three-dimensional structure of mammalian genomes is more diverse than previously seen, with different patterns of chromosome folding identified in various species. The research provides new interpretative hypotheses about the plasticity of the genome and its role in evolution.

SourceUniversitat Autonoma de Barcelona·JournalCell Reports·TypeComputational simulation/modeling·DateDec 20, 2022

Shrine discovered with rituals never seen to take place before in an Egyptian temple

A recently discovered shrine at the Berenike site in Egypt's Eastern desert has provided unprecedented discoveries linked to the presence of the Blemmyes, a nomadic people. The Falcon Shrine contains offerings such as harpoons and cube-shaped statues, as well as a stele with indications related to religious activities.

SourceUniversitat Autonoma de Barcelona·JournalAmerican Journal of Archaeology·TypeObservational study·DateOct 6, 2022

Researchers identify cells causing neuronal death in a mitochondrial disease animal model

In a new study, researchers found that microglia cells are responsible for neuronal death in a mitochondrial disease mouse model. Suppressing these cells with the drug Pexidartinib increased life expectancy and reduced motor problems. Further research is needed to understand the specific process by which microglia attack neurons.

SourceUniversitat Autonoma de Barcelona·JournalGlia·TypeExperimental study·DateJul 8, 2022

Reduction of global inequalities in energy use necessary to stop climate change

A new study by ICTA-UAB reveals that existing climate mitigation scenarios perpetuate energy use inequalities between the Global North and South. To stop climate change, the Global North must reduce its energy consumption to sustainable levels while allowing for sufficient growth in energy use in the rest of the world.

SourceUniversitat Autonoma de Barcelona·JournalThe Lancet Planetary Health·TypeData/statistical analysis·DateJul 7, 2022

Citizens are more supportive of climate action after COVID-19, but more pessimistic in their expectations

A recent study by ICTA-UAB researchers found that the COVID-19 pandemic has led to a shift in public expectations, with many citizens becoming more pessimistic about future climate action. However, some respondents expressed positive views on the impact of COVID-19 on consumption habits and environmental awareness.

SourceUniversitat Autonoma de Barcelona·JournalPLOS ONE·TypeSurvey·DateJun 17, 2022

Scientists call for decision-making to be transformed to tackle the climate and biodiversity crises together

A new article in BioScience argues that incremental changes are insufficient to address planetary emergencies, and calls for broader system-wide changes to governing interactions between climate, biodiversity, and society. The authors hope their work will inform the setting of biodiversity objectives and targets.

SourceUniversitat Autonoma de Barcelona·JournalBioScience·DateJun 1, 2022

Music alleviates collective grief

Researchers analyze viral video of musicians covering Michael Jackson song to understand how it alleviated collective grief during the COVID-19 pandemic. The study identifies key traits that allow empathy and resilience in the face of trauma, highlighting the value of music as a non-pharmacological strategy.

SourceUniversitat Autonoma de Barcelona·JournalBehavioral Sciences·TypeCase study·DateMay 19, 2022

How do genomes evolve between species? The key role of 3D structure in male germ cells

A study by UAB and University of Kent researchers found that the 3D structure of male germ cells plays a key role in determining genome evolution. Genome rearrangements were associated with DNA damage locations in spermatids, suggesting that males have a unique impact on genome evolution.

SourceUniversitat Autonoma de Barcelona·JournalNature Communications·TypeComputational simulation/modeling·DateMay 11, 2022

Marine mollusc shells reveal how prehistoric humans adapted to intense climate change

A study of ancient shell remains found at El Mazo cave site reveals that prehistoric humans in Europe adapted to a 1,500-year cold period by exploiting different mollusc species and avoiding overfishing. This research provides insights into human responses to climate change and its impacts on marine environments.

SourceUniversitat Autonoma de Barcelona·JournalScientific Reports·TypeExperimental study·DateApr 22, 2022

The United States and the European Union are responsible for the majority of ecological damage caused by excess use of raw materials

High-income nations, driven by US and EU, exceed sustainable resource use thresholds by 74% globally. China ranks second in global excess material use, while low- and middle-income countries account for only 8%. Researchers call for transformative post-growth approaches to mitigate ecological breakdown.

SourceUniversitat Autonoma de Barcelona·JournalThe Lancet Planetary Health·TypeData/statistical analysis·DateApr 8, 2022

Study of skin biopsies offers potential as new diagnostic marker for Amyotrophic Lateral Sclerosis (ALS)

Researchers have identified a biomarker, TDP-43, detectable in small skin samples of patients with Amyotrophic Lateral Sclerosis (ALS), allowing for potentially easier diagnosis and early detection. The presence of this protein in the skin of ALS patients is associated with an increased number of fibroblasts with disease marks.

SourceUniversitat Autonoma de Barcelona·JournalCells·TypeRandomized controlled/clinical trial·DateMar 24, 2022

"Advanced" countries’ wealth depends on the appropriation of resources and labour from the global South

A study by Jason Hickel reveals that the global North appropriates vast resources and labor from the global South through price differentials in international trade, resulting in a net drain of $10.8 trillion in 2015. This unsustainable practice perpetuates global inequality and ecological breakdown.

SourceUniversitat Autonoma de Barcelona·JournalGlobal Environmental Change·TypeData/statistical analysis·DateMar 22, 2022

Scientists warn that ocean microplastic pollution may be greater than estimated

A study by ICTA-UAB suggests that microplastic levels in the Mediterranean Sea are likely higher than previously estimated due to the limitations of current sampling methods. The researchers emphasize the need for a common framework to compare results and combine methods to better understand the distribution and impacts of microplastics.

SourceUniversitat Autonoma de Barcelona·JournalEnvironmental Pollution·TypeLiterature review·DateJan 25, 2022

Researchers describe a mechanism that impairs cancer cell proliferation and induces death

Researchers discovered that ERK5 inhibitors activate endoplasmic reticulum stress and UPR in tumor cells, leading to a toxic form of autophagy that causes apoptosis, potentially improving cancer treatment. This finding opens a promising new line for the improvement of chemotherapy and more effective strategies against cancer.

SourceUniversitat Autonoma de Barcelona·JournalFrontiers in Cell and Developmental Biology·TypeExperimental study·DateDec 21, 2021