Researchers analyzed data from nearly 800 families to show that 80% of children who reported maltreatment also experienced emotional maltreatment, leading to severe psychiatric consequences. The study highlights the need for early intervention and education of parents to take a child's perspective.
Researchers have identified a rare gene mutation that causes severe childhood obesity, leading to a constant feeling of hunger and decreased sensation of satiety. The discovery provides a new understanding of the genetic mechanisms underlying monogenic human obesity.
Research at Leipzig University finds that socially disadvantaged individuals have a higher risk of dementia due to modifiable health and lifestyle factors. Lifestyle interventions may mitigate socio-economic differences in cognitive performance.
Researchers successfully reconstructed a two-billion-year-old enzyme, shedding light on an ancient evolutionary mechanism that enables modern enzymes to work efficiently despite interruptions. The study reveals the ancestral enzyme is processive, removing correctly added nucleotide building blocks, and shows how bioinformatics and bioc...
Researchers found that metabolic disease affects blood vessels in different organs, leading to vascular dysfunction and increased risk of diseases. A healthy diet can partially reverse this damage, but some blood vessels may retain the disease signature, making it difficult to fully reverse.
A recent study reveals that cancer cells adopt a softer state to facilitate metastasis, forming a new mechanical state with rigid islands in a fluid environment. This state allows tumors to grow while providing room for soft, motile cells to break out and form metastases.
A recent study found that improved air quality has led to a significant increase in global warming, with aerosols cooling the climate by up to 50% less than expected. This acceleration is largely due to reduced aerosol pollution in North America, Europe, and East Asia since 2000.
A recent study found that mechanical ventilation can cause irreversible tissue damage in premature lungs, leading to impaired lung cell function. The study showed that even low pressure can result in structural changes on the cell surface, disrupting molecule transport and water balance.
A large-scale study of over 80,000 adults from nine countries found no systematic relationship between sibling gender and personality traits such as risk-taking or emotional stability. The results suggest that siblings have a limited influence on personality development in adulthood.
Researchers at Leipzig University Hospital's Clinic and Polyclinic for Hematology discovered two new forms of rare blood cancers, including a molecular mechanism in T-lymphocytes that augments the response to incoming cell signals. The findings have significant implications for diagnosis, prognosis, and treatment planning.
Researchers analyzed the knowledge of chemical space between 1800 and 1869 to discover how well the periodic table corresponds to the chemical data at its formulation. They found that the periodic table's basic structure was already encoded in space by the 1840s, two decades before its creation.
40-million-year-old tropical reef corals from Leipzig University's collection provide a unique climate archive. The coral skeletons reveal small seasonal temperature fluctuations of about half the current value, confirming expected small differences in the planet's warm periods.
A recent study by Leipzig University researchers has identified a rare gene mutation that causes increased cognitive performance and blindness. The mutation affects synaptic communication, leading to improved neuronal function, as demonstrated using fruit flies.
The study reveals that NPY peptides use different 'docking pathways' to interact with their receptors, leading to varying signals in the cell. The flexibility and mobility of the complexes play a crucial role in this process.
Scientists have discovered that mechanical stimuli play a crucial role in activating adhesion GPCRs, which transmit signals via G proteins. The study provides insight into the functional nature of mechanosensitive receptors and has implications for developing future forms of therapy.
Gene expression tests examine how active genes are in tumour cells and have shown that even random genes can be prognostic. Combining multiple tests increases the probability of identifying patients who will not benefit from chemotherapy.
Researchers have created a new method to generate strong fluid flows in tiny channels by heating a metal film with a laser beam, allowing for the separation and transport of nano-objects. This innovation has potential for lab-on-a-chip applications and could lead to advancements in nanoscale manufacturing and sensor technologies.
An international research team reconstructed the genome of Steller's sea cow from fossil remains, finding inactivations of genes responsible for its unique skin structure. The study reveals a dramatic reduction in population size contributing to the species' extinction.
A clinical trial shows that an automated insulin delivery system using an Android app is safe and effective for young children with type 1 diabetes. The system, CamAPS FX, improved metabolic control and reduced blood glucose levels in children aged one to seven years.
A recent study involving over 10,000 participants found that high phytosterol levels are associated with an increased risk of coronary artery disease. The research identified five new genetic loci linked to phytosterol concentrations and their impact on cardiovascular health.
An international team of geomorphologists and physicists has discovered a consistent number in the frequencies of shifting grains, enabling reliable classification of newly discovered sand ripples. This finding could help explain the formation of mysterious new sand waves on Mars and evaluate past climatic conditions.
Researchers at Leipzig University have discovered that cancer cells need the succinate receptor to control their metabolic rate. The receptor is found on the surface of various types of tumors and plays a crucial role in the survival of cancer cells.
A large-scale study has identified thousands of genetic loci regulating blood gene expression, including cis and trans effects found in 88% of genes and 37% of trait-related variants. This research provides new insights into molecular relationships for various traits and diseases.
Scientists have made a breakthrough in understanding the behavior of highly reactive chemical compounds by identifying their binding preferences. This knowledge allows for targeted syntheses and binding of hazardous chemicals, revolutionizing the field of chemistry.
Heavy water significantly reduces cellular dynamics without damaging cells, a finding with implications for organ transplants and tissue storage. The study's results suggest increased interaction between structural proteins and reversible effects, paving the way for further research into this phenomenon.
A global lockdown reduced cirrus cloud formation by 9% and density by 2%, with a positive impact on the climate. This study demonstrates that aircraft contrails contribute to additional cirrus clouds and global warming.
Researchers found that palm oil plantations significantly increase aggressive interactions and reduce bonding behaviors in southern pig-tailed macaques. The study showed that the plantation edge provides a safe haven for social interactions, while the interior poses greater safety risks.
Researchers will investigate how humans have influenced changes to floodplains and when this began, shedding light on the global relevance of an 'anthroposphere'. The project will employ innovative methods combining archaeology, geosciences, and history to understand human-environment interactions.
A new study reveals that patients with newly diagnosed incurable cancer experience significant physical and emotional distress, including anxiety and depression. Comprehensive palliative care services are essential to address these needs and improve quality of life for patients.
Researchers developed microswimmers that can change direction by heating tiny gold particles, then learned to navigate through a virtual environment via external control and virtual rewards. The findings suggest an optimal speed is key to navigation, with implications for autonomous tasks and collective behavior in biological systems.
Researchers at Leipzig University have developed a new model that enables precise determination of the features in complex pore networks, revealing potential applications in drug release, sensor technology and energy storage.
Researchers discovered that human tumours contain solid and fluid cell clusters, enabling cancer cells to move and multiply. The study's findings could lead to improved cancer diagnosis and therapy, with potential applications in detecting metastatic cancer cells.
A portable, suitcase-based laboratory provides rapid and accurate SARS-CoV-2 testing in regions with limited infrastructure. The mini-lab uses a recombinase polymerase amplification method, producing results in under 15 minutes.
Researchers have elucidated the molecular structure of the Y2 receptor, enabling the development of targeted drugs for treating epilepsy and cardiovascular diseases. The study reveals that Y2 receptor blockers bind differently than comparable molecules at the closely related Y1 subtype.
A recent study by Anne-Marie Elbe and her team of researchers found that a task-oriented training climate correlated positively with young players' sense of inclusion in football teams. In contrast, a performance-oriented motivational climate was negatively associated with feelings of inclusion.
Researchers have identified electrical oscillations in Parkinson's patients' scalps that are coupled with brain activity, suggesting a key to understanding the disease's characteristic movement slowing. The study's findings could lead to novel therapies and shed light on the connection between cognitive disorders and motor symptoms.
Research from Leipzig Authoritarianism Study 2020 shows a decline in xenophobic attitudes, but old resentments are paired with new radicalism. The study found that authoritarian and anti-democratic attitudes remain a threat to German society.
Research found that only 12% of ecosystem functioning variance can be explained by plant traits, highlighting the complexity of long-term ecosystem changes. Plant biomass production and pollination patterns varied greatly among years and communities.
Research found that cancer cells losing 'stickiness' allows them to move freely, but dense environments can still hold them back. This contradicts previous understanding of cell movement in cancer development.
A long-term study found that the COVID-19 pandemic significantly decreased average life satisfaction and positive feelings among Germans. Those who perceived the crisis as a challenge and used constructive coping strategies reported higher subjective well-being.
Scientists have created a highly sensitive glyphosate detection method using elastic hydrogel microparticles that inhibit binding to a chip surface. The method offers an extremely high level of sensitivity with regard to pesticide limits for drinking water.
A team of physicists at the Universität Leipzig is developing an ultra-compact spectrometer with potential applications in industries such as food, medicine, and textiles. The new instrument could make quality control cheaper and more accessible, allowing for widespread adoption and democratizing access to spectral analysis.