A nationwide effort to prevent necrotizing enterocolitis (NEC) in newborns has been launched with a $1.9 million Department of Health and Human Services grant. The grant will fund the distribution of an NEC prevention bundle, NEC-Zero, to help neonatal intensive care units recognize and prevent NEC.
A new study identifies phosphatidylinositol 4,5-bisphosphate as a key regulator of the SK2 channel, which plays a critical role in cardiac ion channels and heart rhythm. The research provides critical translational insights into possible mechanisms of cardiac arrhythmias in heart failure.
Researchers seek to identify Hispanic women at risk of developing chronic diseases through early screenings or interventions, aiming to improve health outcomes for millions in the population.
Researchers at the University of Arizona Health Sciences are studying the molecular mechanisms of coagulation factor XII as a contributor to heart failure with reduced ejection. The goal is to develop better preventive and treatment options for this irreversible condition, which affects millions of Americans.
The Arizona Center for Rural Health has been awarded two $4.4 million HRSA grants to improve health services in rural communities. The grants will support Critical Access Hospitals and EMS providers through training programs, data collection, and operational improvements.
The University of Arizona College of Nursing will receive a $1.6 million grant from the Indian Health Service to support Indigenous students pursuing nursing careers. The grant will also fund partnerships with tribal communities, aiming to increase the number of highly trained Native American nurses and improve healthcare in Native Ame...
A global network will be created to protect Indigenous data collection and use, leveraging worldwide policies and practices to ensure control over data related to Indigenous communities. The project aims to establish an alliance among 12 Indigenous data sovereignty networks spanning the globe.
A new study found that living near areas where pesticides were used during the first trimester of pregnancy or pre-conception increases the risk of stillbirths. Researchers linked pesticide use records to state birth certificate data and found specific chemicals, such as organophosphates and pyrethroids, to be associated with increased...
The review paper examines the scope of people affected by long COVID, ranging from fatigue to cognitive impairment, and current treatment options. Researchers emphasize the need for biomarkers and targeted therapies to address root causes of the disease.
Researchers found that adults with chronic pain experience higher rates of anxiety and depression but access mental health care at lower rates. Only 44.4% of those with chronic pain received adequate treatment for their symptoms, compared to 71.5% without chronic pain.
Researchers identified a viable path to developing a novel therapy that would make opioids more effective and safer as a treatment for chronic pain. The study found that selective Hsp90 inhibitors amplified the pain-relieving effects of morphine, reducing tolerance and side effects.
A recent study published in BRAIN found that males and females differ in their experience of pain due to functional sex differences in nociceptors. The findings support the implementation of a precision medicine-based approach considering patient sex as fundamental to treatment choices.
A study led by researchers from the University of Arizona Cancer Center identified a biological mechanism that could lead to more effective treatments for breast cancer that has metastasized to the brain. By targeting the autophagy pathway, the researchers were able to disrupt breast cancer cells' ability to form brain metastases.
A 15-year analysis of national data on suicides and homicides shows that nocturnal wakefulness significantly increases the risk for both. Disrupted sleep impairs rational thought and drives impulsive behaviors in vulnerable individuals.
Researchers found that five cannabis terpenes reduced chronic neuropathic pain levels comparable to morphine. The combination of terpenes and morphine enhanced pain relief without negative side effects. Terpenes offer an alternative to opioids for pain management with a better side effect profile.
Researchers are working to make publicly funded data collection in computed tomography widely available and understandable by diverse communities. The Non-Clinical Tomography Users Research Network aims to improve data handling across scientific disciplines and standardize data acquisition, handling, and sharing.
A new study found that experienced firefighters have different epigenetic modifications linked to prostate cancer risk compared to new firefighters. Chemical exposure to PFAS is associated with these changes. The research team investigated fire department data and found a link between PFAS exposure and increased prostate cancer risk.
The Campos Lab will investigate how human papillomavirus moves from lower epithelial cells to the upper layers and into the nucleus, where it hijacks the cell to make copies of itself. By understanding this process, researchers hope to shed light on cell division and viral transmission.
Researchers have identified a novel protein FOXF1 that stabilizes blood vessels inside lung tumors, decreasing intertumoral hypoxia and preventing lung cancer metastases. Increasing levels of FOXF1 or FZD4 shows promise to improve therapeutic outcomes in lung cancer patients.
Researchers will explore health effects of fire exposure in the wildland-urban interface, measuring exposure risk and evaluating effective interventions such as rapid reporting of data and improved personal protective equipment. The study aims to reduce firefighter health risks and improve overall public health responses.
A researcher at the University of Arizona is using a $750,000 NIH grant to develop methodology for reducing asthma risks among nurses. Preliminary survey data suggest that nurses prioritize lower asthma risks over increased infection risks.
A new study by UArizona Health Sciences researchers found that sleep disturbances increase the vulnerability to migraine attacks. Improving sleep health may decrease the likelihood of migraine attacks in people with migraine. The study used preclinical mouse models and found no link between migraine-like pain and disrupted sleep.
The University of Arizona College of Medicine – Tucson has received a $2.7 million grant from the Juvenile Diabetes Research Foundation to test an implantable device that could eliminate the need for glucose testing and insulin injections in people with Type 1 diabetes. The device, developed by Professor Klearchos Papas, uses oxygen-en...
Renowned expert John Galgiani, MD, shares current body of knowledge about endemic fungal diseases, focusing on Valley fever and histoplasmosis. Early diagnosis is crucial to avoid unnecessary treatments and complications.
Researchers have successfully genetically modified pluripotent stem cells to evade immune recognition, offering a viable path forward for pluripotent stem cell-based therapies. The study's findings suggest that these engineered stem cells could pave the way for new treatments for diseases such as Type 1 diabetes and macular degeneration.
The center will focus on research and programs to help communities in Arizona and other hot, dry geographic regions adapt to climate-driven health threats. SCORCH aims to build resilience through cross-disciplinary research and community engagement.
Researchers at the University of Arizona College of Medicine – Tucson used stem cell technology to improve research models for Parkinson’s disease, uncovering clues that may help scientists detect the condition earlier and develop better treatments.
UArizona researchers are conducting a four-year clinical trial to investigate the effectiveness of angiotensin 1-7 as a potential treatment for TBI. The study aims to address the underlying inflammatory reaction that drives long-term effects of TBI.
A new study aims to improve methadone treatment by developing and testing a patient-empowered, trauma-informed protocol in Arizona. The MPACT study has shown promising results, reducing opioid overdoses by 80% with access to methadone treatment.
Researchers at the University of Arizona Health Sciences received a $13.1 million grant to study how to improve immune defense in older people. The goal is to create interventions that can help combat age-related decline in T cells, leading to better health outcomes and reduced healthcare expenses.
A portable virtual reality system will be developed to quickly assess traumatic brain injuries in remote locations, utilizing AI-powered machine learning algorithms. The system aims to provide a rapid and fine-grained assessment of neurocognitive abilities, increasing the survivability and readiness of US soldiers.
The University of Arizona Health Sciences' AZ-HOPE program has received a $3.2 million grant to support students from economically or educationally disadvantaged backgrounds in pursuing careers in healthcare. The program aims to help these students overcome barriers and achieve their dreams of becoming health professionals.
Researchers at the University of Arizona Health Sciences will train the next generation of translational scientists in Alzheimer's disease research through a $1.4 million grant. The program aims to develop highly trained, cross-disciplinary researchers to address the complex challenges of this devastating neurodegenerative disorder.
A new study found that nearly 40% of eligible adults did not receive a COVID-19 booster due to prior infection with SARS-CoV-2 or concerns about vaccine side effects. The researchers hope the findings can inform design of interventions to improve vaccination rates.
Researchers are investigating gastrointestinal symptoms, specifically irritable bowel syndrome, as a condition of long COVID using a $3.2 million grant. The study aims to better evaluate and treat COVID-19-related IBS by analyzing data from the Arizona CoVHORT research study.
A team of researchers identified a protein called RAC2 that appears to drive the foreign body response, which causes the body to reject biomedical implants. Suppressing production of this protein could reduce the risk of implant rejection and improve the design and safety of implants.
Researchers from the University of Arizona Cancer Center have identified a new method of activating specific molecules to target cancer cells while leaving healthy cells unharmed. The team developed crPROTACs, which allow for the activation and release of proteins only in cancer cells.
A new study found that nearly 1 in 20 adults in the US experience co-occurring chronic pain and anxiety or depression, resulting in functional limitations. The study analyzed data from 31,997 people and found that approximately 12 million people, or 4.9% of the adult population, have co-occurring symptoms.
Researchers at UArizona Cancer Center have discovered a new class of iron-targeting compounds that exploit the iron dependency of malignant cells. These compounds could lead to the development of broad-spectrum, anticancer drugs targeting iron metabolism.
The ROSA program aims to demystify basic science research and facilitate culturally tailored approaches to address health disparities in vulnerable communities. Researchers developed strategies to build collaborations between basic scientists and Hispanic community members, resulting in a 17-member working group.
The University of Arizona College of Nursing will deploy immersive managed practice adaptable clinical training starting in the spring semester of 2024, supporting 19 students per year with $25,000 each. The grant also helps establish a longitudinal clinical placement model and provides financial support for community partners.
The University of Arizona Health Sciences has been awarded a National Institutes of Health training program grant worth $750,000. This funding will continue to support master's students pursuing degrees in environmental and occupational health in the Industrial Hygiene Program.
The National Cancer Institute is supporting a new training program at the University of Arizona, which aims to introduce students to careers in cancer prevention science. The 10-week program will provide hands-on research experience to 75 undergraduate and 25 graduate students.
Researchers will evaluate a flexible, personalized sleep health intervention for 20 fire agencies across Arizona, aiming to train fire service managers and promote sleep benefits within the fire service. The study seeks to identify key factors for successful implementation of workplace sleep coaching.
A recent study found that people of color with alcohol use disorder receive less suicide prevention care at emergency departments, despite similar levels of elevated suicide ideation. The research highlights the need for healthcare providers to address disparities in behavioral health care and provide culturally sensitive treatment.
Researchers found that morphine interacts with toll-like receptor 4 to contribute to increased bone loss and pain. Blocking TLR4 prevents these effects, suggesting a new target for reducing opioid side effects.
Researchers at the University of Arizona Health Sciences have discovered a way to enhance pain relief with opioids while reducing side effects. By inhibiting heat shock protein 90, they found that AMPK can block or reduce pain relief by opioids, providing a new pathway for improved therapy.
Researchers at the University of Arizona College of Medicine – Tucson used AI to map molecular changes in healthy brain cells and identify upstream genetic points that trigger Alzheimer's disease. The study provides clues to the disease's origins and potential drug targets.
A University of Arizona Health Sciences study found that people over 45 with Type 2 diabetes treated with anti-hyperglycemic medications had a higher risk of multiple sclerosis, especially among women. In contrast, anti-hyperglycemic exposure in those under 45 reduced the risk.
Researchers at the University of Arizona Health Sciences found that morning blue light therapy improved sleep quality and reduced PTSD symptom severity in patients. The study's results suggest a potential non-invasive treatment approach for retaining benefits of therapy long after treatment ends.