A no-deal Brexit may lead to exclusion of the UK from 24 European Reference Networks, which provide specialized care for patients with rare diseases. The networks have improved patient outcomes and collaboration among experts; their removal could diminish access to clinical trials and funding.
In a groundbreaking study, gene therapy injection in one eye significantly improved vision in both eyes, with 78% of patients experiencing significant visual improvement. The treatment has shown promise in treating Leber hereditary optic neuropathy (LHON), a blinding condition affecting approximately 1 in 30,000 people.
New lipid residue analyses reveal a dominance of animal products in ancient ceramic vessels from rural and urban settlements of the Indus Civilisation. The study identifies a predominance of non-ruminant animal fats, contradicting previous assumptions about the region's diet.
Researchers from the University of Cambridge discovered a hidden symmetry in quantum systems that allows entangled particles to remain linked despite noise. This finding could lead to the development of ultra-powerful quantum computers by preserving quantum effects in noisy environments.
A new study from the University of Cambridge found a significant increase in depression symptoms among children during the first UK lockdown. The study, which followed 168 children over time, showed that even small increases in emotional problems and anxiety were observed.
A study by University of Cambridge researchers found specific cell functions reactivated in the gut of children with Crohn's Disease. The research provides insight into fundamental molecular mechanisms of human gut development and may lead to childhood-specific treatments.
New research suggests that dolutegravir, a widely used 'wonder drug' for HIV treatment, may not be as effective in patients with resistant strains of the virus. The study found that individuals with efavirenz-resistant mutations were less likely to achieve viral suppression when treated with dolutegravir.
Astronomers have detected fast-moving carbon monoxide gas flowing away from a young, low-mass star, which may provide insight into how our own solar system evolved. The gas is thought to be produced from icy comets being vaporised in the star's asteroid belt.
Researchers at the University of Cambridge found that domperidone, an anti-nausea medication, can significantly reduce how much volunteers look away from disgusting images. The study suggests that stabilizing the stomach's electrical signals may be a key cause of disgust avoidance.
New research from the University of Cambridge shows that targeting the education of the world's poorest children and marginalized girls can significantly improve the attainment of all young people. The study found that interventions like CAMFED's bursaries for disadvantaged girls lead to notable academic improvements, including improve...
New research reveals significant racial disparities in murder victimisation rates, with Black people facing over five times the risk of White British people. Researchers call for more accurate crime data to inform policing strategies and promote fact-informed dialogue with communities.
A new computer vision app developed by University of Cambridge engineers allows easier monitoring of blood glucose levels in people with diabetes. The app uses a smartphone camera to read glucose meter data, eliminating the need for manual input or internet connectivity.
A new study found that noradrenaline helps us adapt to uncertain situations by allowing rapid learning and adjusting our behavior. In contrast, Propranolol blocks the action of noradrenaline, making people more reliant on past experiences in the face of uncertainty.
Research finds no direct link between early language environment and literacy skills at age 11, but suggests identifying 'learning pathways' during primary school can help teachers devise personalized strategies to support children who fell behind. The study used data from over 7,000 children to map out the interdependencies between ea...
A recent study found that mammals, birds, and amphibians have lost an average of 18% of their natural habitat range due to land use changes and climate change. The loss could increase to 23% by 2100 in a worst-case scenario.
Scientists have used gene therapy to regenerate damaged nerve fibers in the eye, potentially leading to new treatments for glaucoma. The technique stimulated regeneration and protected retinal neurons from cell death, offering hope for protecting vision loss.
Researchers uncovered the SARS-CoV-2 genome's 'origami' structure, revealing long-distance RNA interactions critical for replication. This discovery could lead to targeted therapeutics and inform new treatments for COVID-19.
A team of researchers has identified a mechanism to target amyloid-beta, a disordered protein involved in Alzheimer's disease. By designing drugs that bind to the protein in its disordered state, they hope to reduce toxic cluster formation and develop new treatments.
A study in mice confirmed in human samples shows that the brain is protected against infection by immune cells from the gut. The meninges form an impermeable barrier preventing immune cells from entering the brain, but plasma cells secrete antibodies to defend the perimeter of the brain.
A study published in the British Journal of General Practice found that poor awareness of Heart Failure with preserved Ejection Fraction (HFpEF) leads to missed diagnosis and treatment opportunities. The condition affects half of all heart failure cases in England, but frequently goes undiagnosed due to lack of understanding among clin...
Researchers at the University of Cambridge developed a model that analyzes age-specific COVID-19 death data from 45 countries, revealing consistent patterns across countries. The study highlights the importance of focusing on deaths in under-65s for better understanding of infection rates and developing effective government strategies.
A team of researchers tested the effectiveness of different fabrics at filtering ultrafine particles, comparable to coughing or heavy breathing. Most fabrics commonly used for non-clinical face masks were found to be effective, with N95 masks being highly effective.
A study published in the International Journal of Stroke found that COVID-19 patients who develop stroke are on average 4.8 years older than those who do not. Pre-existing conditions such as high blood pressure, diabetes, and coronary artery disease also increase the risk.
A new study suggests that targeting a single brain region called the subgenual anterior cingulate cortex (sgACC) could lead to better outcomes for people with depression and anxiety. Over-activity in sgACC underlies several key symptoms of mood and anxiety disorders, but an antidepressant only successfully treats some of the symptoms.
A study published in Nature Microbiology reveals that drug-resistant E. faecium can spread within hospitals despite deep cleaning, with high rates of infection found in vulnerable patient groups. The bacteria's ability to evade cleaning measures poses a significant challenge to infection control.
Researchers have developed a form of gold nanotubes that can target and kill mesothelioma cancer cells using light. The nanotubes are made in a two-step process and have physical properties that can be tailored for enhanced therapies.
A new study reveals that countries relying heavily on global trade are more vulnerable to resource scarcity, especially in the face of climate change. The research highlights the need for a systemic approach to examining pressures on water, energy, and land resources.
Researchers have grown three-dimensional models of key lung tissue, known as 'mini-lungs,' to study how SARS-CoV-2 damages the lungs. The models revealed that viral replication occurs rapidly within six hours, triggering an immune response and leading to cell death and damage.
New research reveals that our brains favor experiences that end well, weighing the final moments more heavily than the rest of the experience. This 'happy ending effect' can lead to bad decisions when choosing whether to repeat an experience.
A new international study has identified how much traction some prominent COVID-19 conspiracy theories have within populations in the UK, US, Ireland, Mexico, and Spain. The research found that a small increase in perceived reliability of conspiracies equates to a larger drop in intention to get vaccinated.
Researchers at the University of Cambridge developed vLUME, a virtual reality software that allows for the visualization and analysis of complex biological data. This enables faster testing and analysis, leading to new discoveries and insights into fundamental problems in biology.
Researchers have developed a new hyperpolarisation technique to monitor cancer drug efficacy, potentially replacing tissue biopsies. The method detects biomarkers like FOXM1, indicating drug resistance in ER-positive breast cancer.
A study of over 100 children in China found that playmates with bad tempers led to more aggressive pretend play. However, a child's own temperament did not predict this outcome, suggesting that make-believe aggression may actually help social and emotional development.
A new study characterizes the microbial diversity of ancient gut contents from medieval latrines, providing insights into pre-industrial agricultural populations' microbiomes. The research highlights the value of ancient latrines as sources of bio-molecular information, shedding light on the health of modern microbiomes.
Research reveals that a group of parasitic finch species in Africa have evolved to mimic their host's chicks with astonishing accuracy. The study found that nestlings of these 'brood-parasitic' finches mimic the appearance, sounds and movements of their grassfinch host's chicks.
Researchers from the University of Cambridge used 3D printing to create sensors beyond conventional film-based devices, outperforming commercial sensors in monitoring rapid breathing. The fibre sensors can detect breath moisture leaked through face coverings, providing potential indicators for viral transmission protection.
Research from University of Cambridge suggests widely-used 'mixing ventilation' systems disperse airborne contaminants evenly, potentially increasing exposure to COVID-19. The study highlights the importance of good ventilation and mask-wearing in mitigating transmission.
Researchers used tree rings to create a precise yearly record of summer temperatures in North America and Eurasia, revealing colder and warmer periods. The study shows that the effect of volcanoes on global temperature changes is even greater than previously thought.
A study of tree rings from Norilsk, Russia has shown that industrial pollution in the Arctic region has a far greater impact than previously thought. The research reveals widespread damage to the boreal forest, with declining tree growth affecting carbon sequestration and global climate.
Butterfly species that rely on finding a shady location to keep cool are at risk of population decline due to climate change. Landscapes with diverse features and microclimates can help conserve butterfly populations.
A new study by the University of Cambridge suggests that India's government used nudge theory to maintain a strict lockdown and influence public behavior during the first three months of the COVID-19 pandemic. The campaign included policy nudges, social media campaigns, and appeals to powerful values such as patriotism and community.
A new study suggests UK police are neglecting to recognize modern slavery in cannabis farm cases, where migrants are forced into illegal work. Researchers argue that arresting officers often lack detailed training on modern slavery and make only cursory enquiries.
A new study found that ARPA-funded startups filed more patents and achieved higher business success rates than those without such funding. The researchers argue that a UK version of the agency could support energy innovation and help the country close its R&D investment gap.
Researchers from the University of Cambridge used numerical experimentation to determine the limits of matt structural colour in the visible spectrum. They found that saturated, pure colors like reds, yellows, and oranges are difficult to recreate using this method, with blues and greens being the most feasible options.
A new study reveals that autistic individuals are 1.5 to 4.3 times more likely to have chronic physical health conditions, including low blood pressure, arrhythmias, asthma, and prediabetes. Autistic females also face increased risks of these conditions, depending on their biological sex.
Researchers used AI and quantum mechanics to study dense metallic hydrogen, finding a smooth and gradual transformation from molecular to atomic phases. The discovery resolves long-standing debates on the nature of dense hydrogen and has implications for understanding giant gas planets.
A study published in European Respiratory Journal found that COVID-19 patients developed pneumothorax at a 0.91% incidence rate. Survival rates were higher among younger patients, while older patients and those with acidosis had poorer outcomes.
Researchers found that mountainous residents exhibit traits of low agreeableness, introverted self-reliance, and high openness to experience, reflecting the 'Wild West' ethos. This effect persists even among those born and raised outside these regions.
A new approach to diagnosing COVID-19 combines rapid point-of-care nucleic acid testing with antibody tests, resulting in a significant increase in detection rates. The combined method was shown to be 100% accurate in identifying patients with moderate to severe COVID-19 disease.
The complete dinosaur skeleton of Scelidosaurus has been studied in detail, revealing new insights into its anatomy and relationships. The analysis suggests that Scelidosaurus was an early ancestor of ankylosaurs, a group of armored dinosaurs.