A study by University of Nottingham researchers found that higher levels of GABA in the supplementary motor area (SMA) help dampen down hyperactivity, allowing stronger signals to produce movement. This could lead to targeted approaches controlling tics using transcranial direct-current stimulation (tdcs).
A study by University of Nottingham researchers found that smart meters displaying individual and communal energy usage can lead to feelings of shame, anger, and guilt among housemates. This may result in increased conflict and negative emotions, particularly when one or more housemates are free-riding on others' energy usage.
Despite significant increases in R&D expenditure as a percentage of GDP, China has seen a decline in funding for applied research, with basic research funding plummeting from 5.2% to 4.7%. The authors argue that further reforms are needed to bring transparency and coordination to the country's R&D spending.
Researchers have discovered new materials capable of repelling bacteria, which could lead to a significant reduction in hospital infections acquired through implanted medical devices. The polymers have been licensed to a UK SME for clinical trials, aiming to inform rational design of improved bacteria-resistant polymers.
Researchers have completed a comprehensive study on the role of protein phosphatases in malaria parasite development and differentiation. The study, published in Cell Host and Microbe, identifies 16 genes that are crucial for parasite growth and could be future drug targets.
A first-year Environmental Science student at the University of Nottingham Malaysia Campus published a literature review on the Southeast Asian monsoon in Geoscience Frontiers. The study found that future climate warming could lead to a 15-day delay in the monsoon onset by the start of the next century.
A breakthrough in diagnostic technology could make it easier to detect pathogenic bacteria, particularly in developing nations. The innovative approach involves hijacking bacterial metabolic machinery to grow polymers that selectively bind to specific bacteria.
Researchers have identified a new and accurate test for Parkinson's disease using 3T MRI scanning technology, known as the 'swallow tail' appearance of the healthy nigrosome. This sign is absent in Parkinson's disease, making it a potential diagnostic tool for clinicians.
Children and young adults with epilepsy are more likely to suffer broken bones, burns, and poisonings compared to those without the condition. Young people with epilepsy are at significantly greater risk of being poisoned by medication, especially in the age group of 19-24 years old.
Scientists discovered that species with germ plasm, a cell lineage responsible for producing gametes, evolve faster than those without. This accelerated rate of evolution leads to 'explosive radiations' of species and challenges traditional views on the process.
Scientists at the University of Nottingham have developed a new substance to simplify stem cell manufacturing, enabling mass-production of complex living materials. The innovation allows for both self-renewal and differentiation in a single step process, with implications for regenerative medicine.
A new clinical test called NPI+ has been developed to improve breast cancer treatment by providing more detailed information about a patient's cancer type and behavior. This will help clinicians create a more personalized treatment plan, leading to improved outcomes and reduced costs.
International cricket attendance is largely driven by team strength, according to new research. The study found that strong teams draw bigger crowds, even if the match is an unequal contest.
Researchers discovered a new layer in the human cornea that plays a vital role in fluid flow from the eye. This finding could shed light on glaucoma, a devastating disease caused by defective drainage of fluid.
Scientists at the University of Nottingham are developing non-invasive measurements using magnetic resonance imaging (MRI) to assess blood flow and oxygenation in the human kidney. The goal is to improve monitoring and treatment for chronic kidney disease, which can be caused by health conditions like diabetes and high blood pressure.
A team of researchers led by Professor Michael Holdsworth has identified the central mechanism for detecting nitric oxide (NO) in plants, which regulates growth and response to environmental stress. The 'master regulators' control NO detection and have been found to regulate important aspects of plant development.
Researchers found that inhibiting STAT1 chain formation can block detrimental type-II interferon responses while preserving anti-viral protection, providing a new target for improving current treatments.
Researchers at University of Nottingham develop novel MRI method for diagnosing and treating Irritable Bowel Syndrome (IBS), allowing continuous bowel imaging with no risk to patients. The technique enables measurement of colon volumes, transit times, and effects of FODMAPs on gut health.
Researchers at University of Nottingham discovered a potential drug to reduce osteoarthritis pain by targeting cannabinoid receptor2 (CB2), which also reduces joint inflammation. The synthetic compound JWH133 showed promise in animal models and human spinal cord tissue studies.
Researchers will investigate global practices and principles of life imprisonment, aiming to make recommendations on its application. The study will focus on human rights, conditions of service, and the controversial question of irreducible life sentences.
Research teams compared climate simulations to assess drought, water scarcity and river flooding impacts. The study found that frequency of drought may increase by over 20%, while 40% more people are at risk of absolute water scarcity without reduced greenhouse-gas emissions.
A research team has discovered a second rare genetic mutation that strongly increases the risk of Alzheimer's disease in later life. The mutation is found in the Phospholipase D3 (PLD3) gene, which influences amyloid precursor protein processing and may be a potential therapeutic target.
Scientists at the University of Nottingham have discovered a mechanism controlling tics in children with Tourette Syndrome. The study found that brain changes can alter excitability ahead of voluntary movements, suggesting a potential therapy to help young people overcome tics.
A study by Dr James Stratford and Dr Simon Park found that Bacillus mycoides responds to subtle changes in its environment, producing whirlpool-shaped structures in response to curved surfaces. The microbe's ability to respond to force could signal potential useful scientific applications.
Researchers found compelling evidence that gout clusters in families, with a significant increase in risk for those with first and second-degree relatives affected. The study also highlights the role of shared environmental factors, such as diet and lifestyle, in predisposing individuals to gout.
A study by University of Nottingham researchers found that Malaysian drivers are less likely to identify situations as dangerous and react to them later than British drivers. The study suggests that hazard perception tests may need to be adapted for developing countries where road safety is a primary concern.
Researchers have discovered a new method of delivering chemotherapy drugs directly to brain tumours using a polymer originally designed to mend broken bones. The therapy has shown promising results, reducing toxic side effects and potentially leading to more effective treatment and prolonged patient survival.
Researchers have discovered that polymers can disrupt the way bacteria communicate with each other, leading to unexpected clustering behaviors. This finding has significant implications for the design of materials as antimicrobials, bioprocessing, and synthetic biology.
Researchers at the University of Nottingham have found a type of archaea that can reproduce without normal replication processes, growing faster in its absence. This discovery challenges existing understanding of DNA replication and has implications for cancer research.
A new study conducted at the University of Nottingham has found that strong genetic factors do not influence handedness. The researchers examined nearly 4,000 subjects and were unable to detect a single major genetic determination for handedness.
A new study will offer young people living in residential care homes or with foster carers the chance to speak out about why they self-harm. The project aims to identify common themes leading to self-harm behavior and highlight successful services supporting looked-after youth in recovery.
Researchers at the University of Nottingham have developed a highly accurate prototype technique to detect cancerous tissue during surgery. This technique can produce detailed maps of tissue rich in information at the molecular level, enabling fast and objective diagnosis of cancer cells.
Researchers at the University of Nottingham have discovered a faulty 'switch' between brain regions that may cause psychotic symptoms in people with schizophrenia. The study suggests that detecting this disconnection could help identify patients with the condition, and potentially lead to more effective treatments.
Researchers from the University of Nottingham identified a genetic mutation causing blue eggs in native South American and European breeds. The mutation triggered an accumulation of biliverdin, a green-blue pigment, in the eggshell. This finding could inform future research on agricultural breeding techniques.
Conservation scientists work a substantial amount of their time outside regular office hours, with Japanese and Chinese researchers submitting nearly 40% of their manuscripts outside regular office hours. This trend is increasing, with potential negative impacts on the quality of scientific work and life-work balance.
Researchers at the University of Nottingham have found a novel way to block the social communication of bacteria P. aeruginosa, which enables it to cause infection.
Researchers used fMRI and EEG to study brain function, mapping a previously unexplored aspect of brain activity. They found that post-stimulus signal in fMRI reflects changes in brain signalling, not just blood flow.
New research by the University of Nottingham reveals that low levels of neonicotinoid insecticide can alter honeybee gene activity, affecting their development and lifespan. The study's findings support the European Commission's temporary ban on three such pesticides.
The University of Nottingham has established a leading £18 million national power electronics research centre to develop the next generation of power electronics components and devices. The centre will bring together academics and industry partners to create an environment for innovation and knowledge transfer.
Researchers at University of Nottingham have identified a previously undetected layer in the human cornea, known as Dua's Layer. This breakthrough discovery could lead to safer and simpler surgical procedures for patients undergoing corneal grafts and transplants.
A genetic rogue element known as chimeric transcript LCT13 is linked to the silencing of a tumor suppressor gene TFPI-2, promoting cancer invasion and metastasis. The study suggests that 'junk DNA' can interfere with normal cell function, providing new insights into cancer progression.
A UK study found that the £10 million Family Nurse Partnership program can only tackle around 10% of families involved in child maltreatment. Researchers suggest using different risk factors to identify vulnerable children could reach three times more abusive families.
Research suggests that toddlers living in socially-deprived areas are most at risk of suffering a scald. Factors such as age, family size, and parental demographics play a crucial role in determining the likelihood of a child experiencing a hot water-related injury.
Scientists have discovered a stable version of a 'trophy molecule' and found its bonding properties to be surprisingly similar to those of chromium, molybdenum, and tungsten. This finding could aid in the extraction and separation of radioactive material from nuclear waste.
Researchers found that simple games and informal exposure to foreign language words and pictures significantly improved language learning outcomes. The study shows that people can retain knowledge unintentionally learned through informal activities even days later.
A groundbreaking study, funded by £2m from the National Institute for Health Research, will examine ways to improve service user and carer involvement in decisions about their care. The research aims to develop a training package for mental health professionals and test its effectiveness in improving care planning.
Researchers at University of Nottingham found autistic children copy useful actions only, while typically developing children copy both necessary and unnecessary actions. This study offers new insights into social development in children with autism.
A study published in the journal Blood found that pregnant and postnatal women with certain medical conditions, such as varicose veins or heart disease, are at higher risk of developing blood clots. The research also identified other risk factors, including obesity, bleeding during pregnancy or labour, and a history of premature birth.
Scientists at the University of Nottingham are leading a four-year study to investigate the effectiveness of tranexamic acid in treating intracerebral haemorrhage, a devastating type of stroke. The trial aims to recruit 2,000 people worldwide and assess whether the drug can reduce permanent brain damage and improve survival rates.
A study led by the University of Nottingham found that dietary selenium deficiency is likely to be endemic in Malawi, causing disease and premature death. The researchers recommend introducing a programme to enrich nitrogen-based soil fertilisers with selenium to increase levels in maize.