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University of Tsukuba


Discovery of the most intron-rich eukaryotic genome

Researchers used long-read sequencing to analyze the nuclear genome of Amorphochlora amoebiformis, revealing an extremely high proportion of introns (74%) compared to other eukaryotic genomes. The study provides important insights into the evolutionary dynamics and potential functional roles of introns in eukaryotic genomes.

SourceUniversity of Tsukuba·JournalDNA Research·DateDec 22, 2025

Development of the Japanese version of WHO indicators to assess inclusive social participation of persons with disabilities

The University of Tsukuba developed a Japanese version of WHO indicators to assess inclusive social participation of persons with disabilities. The indicators were validated through an online survey among persons with and without disabilities, demonstrating strong internal consistency and construct validity.

SourceUniversity of Tsukuba·JournalDisability and Rehabilitation·DateDec 15, 2025

Refining the uncharted landscape of human transcription factors: a strategic framework for future prioritization

A study analyzed large-scale human ChIP-seq data to identify unmeasured transcription factor-tissue/cell type pairs, revealing significant gaps in current knowledge. These findings indicate that essential regulatory mechanisms may have been overlooked, emphasizing the need for strategic prioritization of measurement targets.

SourceUniversity of Tsukuba·JournalBriefings in Functional Genomics·DateDec 15, 2025

Environmental variability and migration promote the evolution of cooperation among humans: A simulation-based analysis

This study investigates how environmental variability and human migration influence the evolution of cooperation among humans. Simulation results reveal that cooperation is more likely to evolve when these factors are sufficiently high, hindering non-cooperative groups and encouraging cooperative groups.

SourceUniversity of Tsukuba·JournalChaos Solitons & Fractals·DateDec 11, 2025

Lower prevalence of PSC among patients with IBD in Asia: Insights from a multinational study

A multinational study found PSC prevalence among Asian IBD patients to be markedly lower than in Western countries, associated with more favorable clinical outcomes. The proportion of asymptomatic PSC cases has increased due to improved imaging modality detection, allowing for early-stage diagnosis and reduced liver transplantation rates.

SourceUniversity of Tsukuba·JournalClinical Gastroenterology and Hepatology·DateDec 2, 2025

Cartoon-based diabetes education found to be as effective as traditional lectures in enhancing children's knowledge and physical activity

A study by University of Tsukuba researchers found that a cartoon-based diabetes education was comparable to traditional lectures in improving children's knowledge and physical activity levels. The manga-focused approach showed higher psychological satisfaction among participants, leading to improved test scores and physical activities.

SourceUniversity of Tsukuba·JournalClinical Pediatric Endocrinology·DateNov 3, 2025

Identifying factors affecting word processing during second-language English reading at different processing stages

Researchers analyzed eye-tracking data to identify key factors influencing word processing during English reading. Word length was found to be the most critical factor in determining skipped words and total reading time, while word frequency and predictability played a significant role in initial processing and rereading.

SourceUniversity of Tsukuba·JournalStudies in Second Language Acquisition·DateOct 2, 2025

Job changes may cause headaches and insomnia

A nationwide survey of 20,000 people found that those who changed jobs in the past year reported higher rates of health symptoms. Job changers often experience more stress factors, such as late-night shifts and excessive workloads, which can negatively impact mental and physical health.

SourceUniversity of Tsukuba·JournalOccupational and Environmental Medicine·DateOct 2, 2025

Unveiling the mechanism behind sea urchin twinning

Using advanced microscopy and molecular biology, researchers visualized axis reconstruction in sea urchin embryos, tracking cellular movements and gene activation to understand self-organizing ability. This discovery sheds light on the long-standing question of monozygotic twinning emergence from one fertilized egg.

SourceUniversity of Tsukuba·JournalNature Communications·DateSep 5, 2025