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University of Tsukuba


Unraveling the neural circuitry that makes mice attack

Researchers investigated brain mechanisms that maintain balance between intimidation and physical aggression in mice. Projections from the lateral hypothalamus to the dorsal raphe nucleus play a critical role in preserving this balance. Increasing pathway activity led to increased attacks, while inhibiting it decreased attack bites.

SourceUniversity of Tsukuba·JournaliScience·DateApr 1, 2026

Full magnetization hysteresis measurements at MHz frequencies and high magnetic fields

A new magnetic measurement system can reproduce the actual operating environment of next-generation power electronics devices by capturing complete M-H loops up to saturation. The system enables quantitative measurements under high-frequency (MHz-band) and high-field conditions, closely matching real device operation.

SourceUniversity of Tsukuba·JournalIEEE Transactions on Instrumentation and Measurement·DateMar 30, 2026

Quantifying physical performance and identifying knee injury risk factors in rugby players

A longitudinal study has identified key physical performance indicators that contribute to severe knee injuries in rugby players. The analysis found associations between direct contact injuries and greater severity and burden, as well as a high limb symmetry index for hip internal rotation strength and hip extension strength.

SourceUniversity of Tsukuba·JournalThe Journal of Physical Fitness and Sports Medicine·DateFeb 2, 2026

Japanese version of rPATD validated to assess attitudes toward medication reductions among patients and caregivers

The Japanese version of the rPATD questionnaire has been validated to assess attitudes towards medication reductions among older adults and their caregivers in Japan. The tool is reliable, valid, and easily understood, facilitating shared decision-making between healthcare providers and patients.

SourceUniversity of Tsukuba·JournalExploratory Research in Clinical and Social Pharmacy·DateJan 26, 2026

Use of potentially inappropriate medications during end-of-life cancer care: Patterns and factors associated with deprescribing

Researchers analyzed medical records of 1,269 elderly patients with advanced cancer to find that over 70% were prescribed potentially inappropriate medications (PIMs), which declined closer to death. PIM discontinuation was more common among female patients, those with polypharmacy, and palliative care unit admissions.

SourceUniversity of Tsukuba·JournalPalliative Care and Social Practice·DateJan 19, 2026

Discovery of the most intron-rich eukaryotic genome

Researchers used long-read sequencing to analyze the nuclear genome of Amorphochlora amoebiformis, revealing an extremely high proportion of introns (74%) compared to other eukaryotic genomes. The study provides important insights into the evolutionary dynamics and potential functional roles of introns in eukaryotic genomes.

SourceUniversity of Tsukuba·JournalDNA Research·DateDec 22, 2025

Development of the Japanese version of WHO indicators to assess inclusive social participation of persons with disabilities

The University of Tsukuba developed a Japanese version of WHO indicators to assess inclusive social participation of persons with disabilities. The indicators were validated through an online survey among persons with and without disabilities, demonstrating strong internal consistency and construct validity.

SourceUniversity of Tsukuba·JournalDisability and Rehabilitation·DateDec 15, 2025

Refining the uncharted landscape of human transcription factors: a strategic framework for future prioritization

A study analyzed large-scale human ChIP-seq data to identify unmeasured transcription factor-tissue/cell type pairs, revealing significant gaps in current knowledge. These findings indicate that essential regulatory mechanisms may have been overlooked, emphasizing the need for strategic prioritization of measurement targets.

SourceUniversity of Tsukuba·JournalBriefings in Functional Genomics·DateDec 15, 2025

Environmental variability and migration promote the evolution of cooperation among humans: A simulation-based analysis

This study investigates how environmental variability and human migration influence the evolution of cooperation among humans. Simulation results reveal that cooperation is more likely to evolve when these factors are sufficiently high, hindering non-cooperative groups and encouraging cooperative groups.

SourceUniversity of Tsukuba·JournalChaos Solitons & Fractals·DateDec 11, 2025

Lower prevalence of PSC among patients with IBD in Asia: Insights from a multinational study

A multinational study found PSC prevalence among Asian IBD patients to be markedly lower than in Western countries, associated with more favorable clinical outcomes. The proportion of asymptomatic PSC cases has increased due to improved imaging modality detection, allowing for early-stage diagnosis and reduced liver transplantation rates.

SourceUniversity of Tsukuba·JournalClinical Gastroenterology and Hepatology·DateDec 2, 2025

Cartoon-based diabetes education found to be as effective as traditional lectures in enhancing children's knowledge and physical activity

A study by University of Tsukuba researchers found that a cartoon-based diabetes education was comparable to traditional lectures in improving children's knowledge and physical activity levels. The manga-focused approach showed higher psychological satisfaction among participants, leading to improved test scores and physical activities.

SourceUniversity of Tsukuba·JournalClinical Pediatric Endocrinology·DateNov 3, 2025