Articles tagged with Databases
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new open-access database, LitChemPlast, has compiled over 3,500 substances measured in plastic products across 47,000 samples. The study highlights substantial knowledge gaps, including contamination of recycled plastics with hazardous substances and limited regional coverage in low- and middle-income countries.
A new law change proposal aims to provide families of missing persons with an opportunity for closure through burial, rather than cremation. The proposal, backed by expert research, would require DNA sampling before burial to confirm identity and enable family members to make decisions about the body.
The use of GLP-1 receptor agonists (GLP-1RAs) and SGLT2 inhibitors in people with type 1 diabetes has significantly increased between 2010 and 2023. This trend is driven by their benefits in weight management and cardiorenal protection, but caution is advised due to concerns about euglycemic diabetic ketoacidosis.
A new tool, SymGen, enables users to verify AI model responses more quickly and easily by displaying data citations. This speeds up the manual validation process by 20 percent, making it easier for users to spot errors in LLMs deployed in various real-world situations.
A study published in the Chinese Medical Journal projects a significant rise in global thyroid cancer burden, with 821,214 new cases and 47,507 related deaths reported worldwide in 2022. The incidence is expected to increase by 44.1% from 2019 to 2030, with women experiencing higher rates than men.
The new hubs and databases document past environmental events experienced by Arctic societies and provide a more complete picture of past change. They also present contemporary weather and ecological monitoring, cultural indicators, and oral histories to establish baselines of change in the Arctic environment.
Researchers found that certain factors increased the risk of death after sepsis, including advanced age, dementia, heart disease, cancer, and previous hospitalizations. A total of 50.6% of patients with sepsis died within two years, highlighting the need for closer monitoring and follow-up care.
Researchers found those with dyslexia exhibited less implicit bias than those with no disability, while those with dyscalculia showed even less bias compared to both groups. This study provides new insights into the development of people with conditions like dyslexia and dyscalculia.
Researchers explore the influence of digital resources on autobiographical memory, highlighting its potential benefits, such as supporting people with memory difficulties, and risks, like manipulation through deepfakes. The study aims to better understand the interplay between recorded data and memories stored in our minds.
A study published in Nature Communications found that one in eight newborn babies has a genetic protection against jaundice. The researchers identified a specific gene variant that codes for an enzyme linked to increased bilirubin metabolism, providing an opportunity for personalized medicine.
A new review has found that 3,601 food contact chemicals have been detected in human bodies, representing 25% of known chemicals. The study highlights significant gaps in biomonitoring and toxicity data, and emphasizes the need for safer alternatives.
A new study published in Health Affairs found that the Colorado insulin price cap law resulted in a 40% reduction in out-of-pocket costs for insulin prescriptions. The law, which caps monthly costs at $100 for state-regulated health insurance plans, had the largest impact on children and adults aged 18-34, as well as rural patients.
A research team at Hiroshima University developed an analytical pipeline to identify unexploited genes associated with Parkinson's disease and oxidative stress. The study revealed two novel candidate genes, NUPR1 and UHRF2, which were absent from current gene-disease associations databases.
A new library of healthy participants' neuroimaging data has been created to aid in the diagnosis and treatment of traumatic brain injury (TBI). The Normative Neuroimaging Library consists of data from approximately 1900 individuals, providing a comprehensive dataset for clinicians and researchers.
Vultures, like young humans, explore new sites and socialize frequently when they're young. However, as they age from around 10 years old, they scale back on socializing and prefer to stay at the same roosting site, similar to humans who tend to stay home.
A new study published in the Stroke journal found that people with brain aneurysms are at higher risk of developing mental health conditions, including anxiety. The study, which analyzed data from over 85,000 people, found that younger adults were particularly vulnerable to this increased risk.
A disproportionality analysis of World Health Organization data revealed a signal of semaglutide-associated suicidal ideation, particularly among patients with co-reported antidepressant use. This finding warrants urgent clarification and highlights the need for further research on the safety profile of semaglutide.
A study found that energy companies use repeated phone calls, home visits, and 'legalized compulsion' to force homeowners to give up their land for hydraulic fracturing. The researchers reviewed data from Ohio and found that many negotiations end in compulsion rather than consent.
Researchers developed a formula and assessment tool to calculate fall risks for older adults, considering factors like poor oral and cognitive function. The tool is simple to use and may assist in prevention and follow-up care.
A groundbreaking approach inspired by bio-inspired neuromorphic imaging and speckle correlography has unveiled a revolutionary technique for optical image encryption. This method leverages computational neuromorphic imaging to encrypt images into event-stream ciphertexts, significantly enhancing security and complexity.
A population-level study found no increase in neonatal and infant mortality rates during the initial COVID-19 pandemic period. However, social distancing measures were linked to higher preterm birth rates with a lag period.
A new US-based database of hurricane evacuation orders can help leaders and communities increase resilience, create better policy, and ultimately reduce loss of life. The HEvOD database includes nationwide public-facing evacuation orders from 2014-2022, offering insights into effective strategies for future emergencies.
Research by University of East Anglia and University of Texas found that stricter data privacy laws significantly reduced breaches, but negatively affected firms' market value. Companies compliant with GDPR invested more in data protection and were less likely to experience data breaches.
The ELTE Eötvös Loránd University has digitised over 431 animal skulls, including those of 152 dog breeds and 12 wild relatives. This unique collection is now available online, enabling researchers to conduct comparative anatomical and evolutionary studies.
A large-scale study confirms the rising incidence of eosinophilic esophagitis (EoE) in Japan, with a significant increase in cases between 2005 and 2022. The study found an incidence rate of 2.82 per 100,000 person-years and a prevalence rate of 10.68 per 100,000 people.
Researchers have successfully synchronized a 220-year-old map of Southern Germany from the Napoleonic era with modern databases, allowing for tracking of historical and environmental changes. The map was produced in haste during the wars, resulting in errors that were corrected through geospatial analysis.
A global database of animals with four feet has identified significant gaps in tetrapod knowledge, including biases in biodiversity data. Researchers used artificial intelligence to predict missing data and improve the accuracy of ecology, evolution, and conservation studies.
A UCF biologist has compiled a database of animal DNA to study the presence of magnetic bacteria, which may aid in navigation and conservation. The database contains hundreds of millions of genetic sequences showing the presence of various types of magnetic bacteria.
A new version of the OPTIMADE standard enables easier access to large materials databases, facilitating AI modeling and prediction of material properties. The international collaboration involves over 30 institutions worldwide, aiming to advance materials research and development.
Researchers discuss primary hepatic angiosarcoma, a rare mesenchymal liver tumor, and its poor prognosis compared to hepatocellular carcinoma. Diagnosing PHA is critical due to its similar clinical presentation to HCC.
The number of US individuals with chronic hypertension in pregnancy increased significantly, while medication treatment remained low, according to a new study. The findings highlight the need for improved maternal health strategies to address high blood pressure and cardiovascular complications.
A new biomarker database, Space Omics and Medical Atlas (SOMA), has been developed to improve astronaut health, but its findings may also be useful for people on Earth with limited mobility or bedridden conditions. The database provides insights into short and long-term health impacts of spaceflight.
A study published in the European Respiratory Journal found that children exposed to weed pollen in urban environments are at higher risk of developing respiratory health problems, including asthma. However, tree canopy can mitigate this effect to some degree.
A comprehensive, user-friendly repository has been created to help study Alzheimer's disease. The ssREAD database encompasses 277 integrated datasets from 67 scRNA-seq & snRNA-seq studies, totaling 7,332,202 cells, and includes interactive visualizations for comprehensive analysis interpretations.
A study found female health apps exposing users to unnecessary privacy and safety risks through poor data handling practices. Researchers discovered apps coercing users into entering sensitive information that could put them at risk.
A massive open dataset, OpenDAC, has been created to accelerate direct air capture technology development while reducing costs. The database enables the training of an AI model that predicts material interactions with high accuracy, significantly faster than traditional chemistry simulations.
Research suggests that four proposed AI search engines for automating search and retrieval of digital histopathology slides have inadequate performance for routine clinical care. The algorithms showed less than 50% accuracy in some cases, highlighting the need for rigorous external validations and standardization before clinical adoption.
A cohort study found statistical signals for myocarditis and pericarditis after BNT162b2 vaccination in children aged 12-17 years, consistent with previous reports. Seizures after mRNA-1273 vaccinations in younger age groups require a robust epidemiologic investigation to confirm findings.
Ancient marine plankton communities showed subtle changes before major extinctions, serving as an early warning system for future ocean life loss. These findings offer new insight into how biodiversity responds to global warming and its relevance to worst-case scenarios.
A new study reveals that less affluent countries are more prone to damage caused by biological invasions, with average costs exceeding $26.8 billion annually globally. Wealthier nations can mitigate this issue by investing in invasive species management in neighboring countries.
A long-term study found that coronary heart patients who live in greener areas have a significantly lower risk of mortality after undergoing bypass surgery. The study, which followed over 3,000 patients for 14 years, found that living in a green environment was associated with better chances of survival.
Researchers found that nontraditional stroke risk factors like migraines are as important as traditional risk factors like high blood pressure for adults younger than ages 35-45. The association between stroke and nontraditional stroke risk factors was stronger in adults younger than 35 years old.
Dr. Chana Sacks is the new Editor-in-Chief of NEJM Evidence, focusing on providing high-quality, practice-changing evidence for medical professionals. The journal aims to change how medical professionals think about generating evidence while making clinical learning engaging and fun.
Researchers developed a new method to predict thermoelectric materials using AI, avoiding trial-and-error and overfitting. The approach achieved remarkable accuracy in predicting newly available materials, providing guidance for experiments.
Leading investigators are creating a one-stop resource for human pancreatic data, standardizing and disseminating curated information on the human pancreas to foster collaborative and reproducible diabetes research. The PanKbase program aims to provide machine-actionable data following FAIR principles.
Researchers have mapped the protein composition of brain endothelial cells, revealing dysregulation of key molecules involved in cellular processes. This study provides a framework for understanding endothelial signaling pathways during aging and serves as a data basis for future analyses of brain endothelial function.
A database containing over 6,000 agri-environmental policies from 200 countries has been published by the University of Bonn and ETH Zurich researchers. The study found that richer countries tend to implement more eco-friendly measures, while national policies play a significant role in reducing soil erosion.
Researchers at Mass General Brigham have developed two AI foundation models, UNI and CONCH, to advance computational pathology. These models excel in diagnostic accuracy, prognostic insights, and predicting therapeutic responses, with universal applications in anatomic pathology.
Research from the University of Pittsburgh and UPMC found that primary care telemedicine visits are associated with lower antibiotic prescription rates for children compared to virtual-only direct-to-consumer providers. The study highlights the importance of integrated telemedicine within primary care settings.
A new AI-powered tool developed by the University of Copenhagen and 3Shape predicts how teeth will move, allowing orthodontists to ensure braces are neither too loose nor too tight. The tool uses scanned imagery of teeth and bone structures to simulate how braces should fit, reducing trial and error.
Research reveals that rapid-range shift in fish populations is often a sign of impending decline. The study analyzed data from over 2,500 species and found that those shifting at high velocities show marked declines, while core range populations remain relatively stable.
A new study warns that rural pupils in England are facing underachievement in education due to socioeconomic factors. Despite better exam results, rural pupils from disadvantaged homes perform worse than urban pupils from similar backgrounds.
West Virginia University researchers introduced a new database showing occupational licensing's impact on the workforce, highlighting how licenses increase cost and time to enter professions, affecting consumers. The database encompasses 50 jobs across all 50 states, providing insights into licensing standards, fees, and requirements.
The EU-funded BiCIKL project has developed a flagship outcome - the Biodiversity Knowledge Hub - a one-stop portal for understanding biodiversity research infrastructures. The consortium has also created 12 services dedicated to FAIR and linked ready-to-use biodiversity data.
Researchers developed an oxidative stress-based prognostic model for bladder cancer, identifying distinct molecular subtypes and predicting patient outcomes. The model shows promise in tailoring personalized treatment approaches, particularly for patients with low-risk profiles.
Researchers at UCSF have identified AF1q as a universal biomarker for neuroblastoma, a highly aggressive and fatal form of childhood cancer. High-risk cases have a five-year survival rate of just 50%. The study found that silencing AF1q in neuroblastoma cells induces cell death and weakens tumor progression.
Researchers at UCSF used clinical data and a precision medicine approach to identify early risk factors for Alzheimer’s disease, predicting its onset with 72% accuracy. High cholesterol, osteoporosis, and erectile dysfunction were found to be predictive factors in both men and women.
Researchers found XRCC1 to have both positive and negative correlations with prognosis across different tumors. The study also revealed associations between XRCC1 expression and DNA methylation patterns, TMB, MSI, immune cell infiltration levels, and immune checkpoint gene expression.
A comprehensive database of invasive plant impacts in Europe has been created, featuring 266 peer-reviewed publications and 4,259 field studies. The dataset highlights the widespread effects of invasive species on native ecosystems, including impacts on plants, animals, and microbes across various trophic levels.
A population-based study in Germany reveals almost 2 in 1,000 girls and women of childbearing age are prescribed isotretinoin, a medication linked to fetal defects. The study found a significant increase in isotretinoin-exposed pregnancies, highlighting the need for better monitoring and guidance.