Articles tagged with Databases
Researchers at UCSF have identified AF1q as a universal biomarker for neuroblastoma, a highly aggressive and fatal form of childhood cancer. High-risk cases have a five-year survival rate of just 50%. The study found that silencing AF1q in neuroblastoma cells induces cell death and weakens tumor progression.
Researchers at UCSF used clinical data and a precision medicine approach to identify early risk factors for Alzheimer’s disease, predicting its onset with 72% accuracy. High cholesterol, osteoporosis, and erectile dysfunction were found to be predictive factors in both men and women.
Researchers found XRCC1 to have both positive and negative correlations with prognosis across different tumors. The study also revealed associations between XRCC1 expression and DNA methylation patterns, TMB, MSI, immune cell infiltration levels, and immune checkpoint gene expression.
A comprehensive database of invasive plant impacts in Europe has been created, featuring 266 peer-reviewed publications and 4,259 field studies. The dataset highlights the widespread effects of invasive species on native ecosystems, including impacts on plants, animals, and microbes across various trophic levels.
A population-based study in Germany reveals almost 2 in 1,000 girls and women of childbearing age are prescribed isotretinoin, a medication linked to fetal defects. The study found a significant increase in isotretinoin-exposed pregnancies, highlighting the need for better monitoring and guidance.
Incheon National University researchers developed a web 3.0 streaming architecture that reduces delay, improves user experience, and ensures transparency and fairness for real-time services. The proposed system uses Inter-Planetary file system (IPFS) to enable blockchain-based peer-to-peer data storage and caching.
A new set of international criteria has been established to diagnose pediatric sepsis and septic shock in children, aiming to improve clinical care and research globally. The Phoenix Sepsis Score of at least 2 can identify potentially life-threatening organ dysfunction in infected children under 18 years old.
A new database visualizes longitudinal viral respiratory infection data from a NYC cohort, offering insights into host response and illness severity. The Virome Data Explorer provides a publicly-accessible resource for researchers to analyze patterns and changes in infections, symptoms, and gene activity.
A study found that the No Surprises Act's independent dispute resolution (IDR) process would be financially unfeasible for a large portion of out-of-network claims for hospital-based specialties, particularly radiologists. This could undermine patient access to in-network care due to limited bargaining power.
A study published in PNAS found that 70 million years ago, primates' ancestors mostly lived in pairs, with only 15% opting for solitary lifestyles. This flexible pair-living ancestor likely offered benefits such as easier reproduction and thermoregulation.
A study in the JAMA Network Open found that Hispanic and American Indian individuals with breast, colorectal, lung, and prostate cancer were undercaptured in the National Cancer Database, but representation improved over time. Further investigation is needed to understand where these populations seek cancer care.
The São Paulo School of Advanced Science on Precision Livestock Farming aims to empower graduate students and early-career researchers with machine learning, statistical tools, and database systems. The school will provide a platform for them to process vast amounts of data and develop a multidisciplinary approach to PLF.
Researchers at La Jolla Institute for Immunology found that most T cells can still target epitopes on the new Pirola variant, suggesting people may be able to mount a response against it. The study's findings provide positive news in the fight against SARS-CoV-2, emphasizing the importance of vaccination with updated vaccines.
A study by UCLA researchers found that nearly 20% of patients with serious illnesses listed as alive in their medical records were actually deceased according to California data. This discrepancy led to hundreds of wasteful follow-up outreach efforts, straining resources and healthcare workers' time.
The gender gap among top-cited scientists is narrowing, with women now representing 32% of top-cited authors in certain fields, according to a study analyzing 5.8 million international scientific authors. However, significant disparities remain, and efforts to address promotion pathways for gifted female researchers are still needed.
Researchers developed DIRFA, an AI-based program that generates realistic videos with facial animations synchronized to spoken audio, showcasing improvements over existing approaches. The tool has potential applications in healthcare, education, and entertainment, enhancing user experiences.
A new recovery system designed by University of Sydney scientists allowed the retrieval of gigabytes of information after a NASA telescope was damaged in landing. The system, which includes parachutes and SD cards, proved essential to the mission's success and has been tested for use in future science missions.
The Vaccine Adverse Event Reporting System (VAERS) in the US is not meeting its standards, with reports of serious adverse events being missed or ignored. The system relies on voluntary reports from doctors and patients, but staffing issues and conflicting information have led to frustration among those who file reports.
A new database combines distribution and lifecycle datasets to examine the prevalence of different lifecycles globally. The study found that annuals are expected to benefit from climate change, but their increased presence could be devastating for ecosystems.
A new European forest damage database has been created to harmonize records of disturbances caused by insects and diseases. The database contains over 650,000 records mapping insect and disease occurrences in European forests from 1963 to 2021.
Research highlights significantly higher heart attack death rates among American Indian and Alaska Native adults, particularly at younger ages. The study suggests that factors like limited healthcare access, socioeconomic conditions, and restricted health insurance coverage may contribute to these disparities.
The A3D-MOBD is a comprehensive database for studying protein aggregation in twelve model organisms. It contains over half a million predictions of protein regions prone to forming aggregates, providing insights into the basis of this phenomenon.
Researchers have reconstructed a global history of water over the past 2,000 years, showing that the global water cycle has changed during periods of higher and lower temperatures. The study found that when global temperature is higher, rain and other environmental waters become more isotopically heavy.
The BeeBCD project brings together over 18 million bee occurrence records to improve accuracy and accessibility of species data worldwide. This consolidated dataset will support future plant and crop production, as well as scientific communications, and inspire more reporting from under-reported regions such as Asia and Africa.
A new database containing thousands of solar mirror samples offers valuable insights into degradation trends over decades. The Solar Mirror Materials Database (SMMD) provides natural and accelerated exposure data for accelerating test development, design optimization, and manufacturing guidance.
Researchers from Texas A&M University's Department of Geography and collaborating departments aim to improve understanding of how environmental hazards influence human health outcomes. The project, 'Climate-LEAD,' will create robust models using localized data to inform decision-making in vulnerable communities.
A study of 42,586 low-risk patients who underwent surgical aortic valve replacement reveals a 5-year survival rate of 93%. The study used the STS National Database and found that eight-year survival was close to 90%. The results provide a benchmark for outcomes in managing aortic valve stenosis.
A recent study reveals 15%-18% of the Brazilian Amazon is at high risk of ecological disruption by 2050. The regions, often near 'deforestation arc', exhibit low research frequencies and are threatened by climate change.
The MOBIOS+ database is a comprehensive platform for Mindanao's biodiversity information, comprising over 12,813 specimen occurrences. It aims to support researchers and conservationists in identifying species and areas requiring immediate prioritization and action.
Researchers developed a novel approach to predict therapeutic targets for aging and age-related diseases. They trained a domain-specific BioGPT model on biomedical literature, which improved its performance in identifying prospective targets.
A study published in Alzheimer's Research & Therapy suggests a possible association between chronic stress and an increased risk of developing mild cognitive impairment or Alzheimer's disease. The research, conducted on 44,447 individuals between 18-65 years old, found that those with chronic stress or depression had a higher risk of d...
A study by Dr Constantino Carlos Reyes Aldasoro explores the different definitions of a 'model' in cancer research, grouping them into four categories. The researcher analyzes scientific publications to identify trends in model usage, finding that mathematical models have gained popularity and computational models are on the rise.
Researchers have developed a new method to analyze protein production in cells using ribosome profiling, which has the potential to advance cancer research. The technique identifies previously unknown protein coding regions and allows for a clearer picture of protein production rate and location.
A Texas A&M University team, led by historian Dr. Daniel Schwartz, is working to preserve the 2,000-year-old Syriac language, deemed endangered due to conflict and persecution in the Middle East. The project, Syriaca.org, aims to safeguard cultural heritage and make it accessible to expat communities worldwide.
A study analyzing data from KoalaBASE found that car strikes, dog attacks, and chlamydia-related illnesses are responsible for a significant number of koala deaths in South East Queensland. The research suggests that interventions such as road signs, overpasses, and information campaigns can help reduce these fatalities.
Biodiversity researchers can now incorporate nanopublications into their manuscripts to future-proof their assertions on biological taxa and organisms. The newly released nanopublication workflow enables authors to create machine-actionable, FAIR data that can be easily traced back to its origin.
A new spatial database created by Purdue University scientists combines data collected on-site and via satellite to provide detailed maps of planted forests in East Asia. The database lists the most common tree species growing there, such as pine and eucalyptus, and covers 87.0% of planted forest in China.
A new study has shed light on the origins of St Helena's 'liberated' Africans, who were brought to the island between 1840 and 1867. The research reveals that they most likely originated from areas between northern Angola and Gabon in West Central Africa.
A new study published in Genome Biology analyzed the genomes of 2000 dogs from 321 breeds, revealing 25 major groups that match expected breed origins. The research found significant genetic variation among breeds, with wolves exhibiting 14% more variation than dogs.
Researchers analyzed data from the Global Biodiversity Information Facility and found a universal pattern of species abundance distributions, with most species being rare but not extremely rare. The study's findings may help answer Darwin's question about why some species are common while others are rare.
A new study published in BioScience documents the progress of the InvaCost endeavour, which has compiled data on the economic cost of biological invasions. The database now includes over 13,553 entries and provides a clear picture of the major threats posed by invasive species to ecosystems, biodiversity, and human well-being.
Research from Aarhus University suggests that smoking may increase the risk of depression, bipolar disorder, and schizophrenia by 250 percent. The study analyzed genetic data from over half a million people and found that certain genetic variants linked to smoking also contribute to mental illness.
Researchers developed an AI tool called DECIMER that can translate chemical structural formulae into machine-readable codes. This allows for the automatic search and processing of scientific articles containing chemical information.
The new tool, SnorCall, analyzes unsolicited calls to shed light on robocall trends and types of scams. It extracted information from over 232,000 robocalls, including phone numbers used in scams, helping regulators and law enforcement take action.
Researchers have created a database of understudied human proteins to accelerate research. The 'unknome' database assigns a 'knownness' score to each protein based on scientific literature information. Functional screens reveal that many unknown proteins contribute to essential cellular functions.
A comprehensive review of US-based Alzheimer's disease brain imaging studies found that all racial and ethnic minority groups are underrepresented. The gap is narrowing, but the research highlights the need for more diverse samples to capture details of participants' lived experience.
A new study by MIT researchers finds that China's government uses AI-driven facial recognition to suppress dissent, but this approach also spurs the development of better AI tools and other innovative technologies. The study suggests that this 'AI-tocracy' cycle entrenches the regime while stimulating further innovation.
The new policy paper emphasizes the importance of Indigenous knowledge and data in subnational decision-making for a sustainable green transition. It identifies key strategies to enhance inclusion, such as awareness-raising among policymakers, increasing Indigenous representation, and facilitating knowledge exchange.
A recent study by Kyoto University has raised concerns about the authenticity of Big Oil's net-zero emissions claims. The research team found that oil majors are not making sufficient progress in phasing out fossil fuels and transitioning to clean energy, despite their pledges to achieve net-zero by 2050.
A supersized database of over 45,000 traits tracks the behavior, distribution, and life patterns of fruit eaters and birds in Central and South America. The Frugivoria database provides crucial insights into their role in maintaining forest composition and health.
The Adaptive Spatio-Temporal Attention Neural Network (ASTANN) is proposed for cross-database micro-expression recognition. It extracts optical flow information and combines it with facial images to generate new representations, which are then processed by a deep neural network with spatiotemporal attention mechanisms.
A study presented at the American College of Cardiology's Care of the Athletic Heart conference found that only 50% of athletes surveyed reported knowing what sudden cardiac arrest is or being concerned about it during play. The researchers identified 46 cases of sports-related cardiac arrests between 1984 and 2022 involving CPR, with ...
Researchers developed a method to detect forest disturbance by combining strengths from time-series algorithms and 2-date detection methods. The new technique facilitates more effective forest management and policy.
Online radiologists choose studies based on financial attractiveness, leading to delays in high-priority cases. This study found that expedited priority class contained the highest percentage of delayed studies.
Researchers develop a new composite strategy to produce clean Landsat images with reduced cloud and shadow errors. The approach uses an algorithm to select pixels from multiple dates to create a virtual median-value point, detecting and replacing clouds and shadows in the process.
The study revealed lower age-standardized rate of NENs incidence in China (1.14 per 100,000) compared to the USA (6.26 per 100,000). The most common sites for primary NEN tumors progressed were found to be the pancreas, stomach, lungs, and rectum.
GPMeta accelerates pathogen detection in metagenomic sequencing (mNGS) tests, achieving higher accuracy while significantly reducing processing time. The approach uses a succinct hash index scheme and multi-GPU support to handle massive data sets.
The study highlights the importance of language documentation and revitalization to preserve human communication, culture, and cognition. Grambank reveals that language loss is occurring unevenly across major linguistic regions, with indigenous languages in northeast South America, Alaska, and northern Australia at highest risk.
The Grambank database provides an unprecedented level of detail on language structure, showcasing the diversity of human languages. Researchers found that languages exhibit greater similarity to their common ancestors than those they are in contact with, highlighting the importance of genealogical constraints on linguistic diversity.
Human macrophages use Siglec-14 receptors to recognize and engulf carbon nanotubes, leading to inflammation. The discovery could pave the way for developing safer carbon nanotubes and therapies to prevent inflammatory diseases.