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Oxygen vacancy boosting Fenton reaction: A novel approach to fight bacterial infection in bone scaffold

Scientists from Central South University develop a novel approach to address bacterial infection in bone transplantation by enriching H2O2 and amplifying the Fenton reaction. The technique enhances biocompatibility and safety, promising reduced transplant failures and post-operative complications.

SourceInternational Journal of Extreme Manufacturing·JournalInternational Journal of Extreme Manufacturing·DateOct 22, 2023

New tumour-selective light treatment could kill breast cancer cells with greater accuracy and improve tumour control

Researchers at NUS developed a new photodynamic therapy that selectively kills breast cancer cells without damaging surrounding tissues. The treatment uses a biocompatible silicone implant loaded with nanoparticles activated by near-infrared light, reducing the risk of toxicity and improving tumour control.

SourceNational University of Singapore, Yong Loo Lin School of Medicine·JournalACS Nano·TypeRandomized controlled/clinical trial·DateJul 19, 2023

Breast implants after mastectomy associated with very low risk of lymphoma

A new Columbia University study has found that breast implants after mastectomy are associated with an extremely low risk of developing a rare cancer called anaplastic large-cell lymphoma (ALCL). According to the study, only five cases of ALCL were diagnosed among 57,000 women who had undergone reconstructive surgery over 421,000 years...

SourceColumbia University Irving Medical Center·JournalJAMA Network Open·TypeData/statistical analysis·DateDec 2, 2022

Study examines how breast implant surfaces affect immune response

Researchers found that textured-surface breast implants stimulate pro-inflammatory T cell responses, which may lead to chronic inflammation and cancer. Smooth-surface implants showed less immune cell activity, suggesting a potential link between rougher surfaces and breast implant-associated large cell lymphoma (BIA-ALCL).

SourceRice University·JournalNature Biomedical Engineering·DateJun 21, 2021

Silicones may lead to cell death

A recent study published in Scientific Reports found that silicone molecules from breast implants can initiate processes leading to cell death in human cells. The researchers used cultured cells and observed similarities with programmed cell death, which may have implications for the health effects of silicone breast implants.

SourceRadboud University Nijmegen·JournalScientific Reports·DateJun 12, 2020

Good results with autologous breast reconstruction after failed implant reconstruction

A study published in Plastic and Reconstructive Surgery reports that autologous breast reconstruction after failed implant reconstruction is associated with significantly improved patient satisfaction and quality of life. The procedure has an acceptable complication rate, despite some additional challenges related to previous breast ca...

SourceWolters Kluwer Health·JournalPlastic & Reconstructive Surgery·DateJan 30, 2019

Complete surgical excision is the most effective treatment for breast implant-associated anaplastic large-cell lymphoma

A comprehensive study led by MD Anderson Cancer Center researchers found complete surgical excision of the implant and surrounding capsule to be the most effective treatment approach for BI-ALCL, with significant improvements in event-free survival and overall survival compared to radiation therapy and chemotherapy.

SourceUniversity of Texas M. D. Anderson Cancer Center·JournalJournal of Clinical Oncology·DateDec 1, 2015

Round or 'shaped,' implants yield good results in breast reconstruction

A study published in Plastic and Reconstructive Surgery finds that round and shaped silicone implants have similar patient-reported outcomes in breast reconstruction, with few significant differences in quality of life. The researchers evaluated 65 women receiving round implants and 63 receiving shaped implants, finding average scores ...

SourceWolters Kluwer Health·JournalPlastic & Reconstructive Surgery·DateFeb 28, 2013

High-resolution CT scan modeling for creating facial implants aids in facial reconstruction surgery

A preliminary study suggests that high-resolution CT scan modeling allows surgeons to custom-design acrylic implants prior to reconstructive surgery for patients with severe defects in their faces and eye cavities. Long-term outcomes showed no significant complications, sustained improvement of facial deformities, and improved function.

SourceJAMA Network·JournalArchives of Facial Plastic Surgery·DateNov 20, 2006

Infection in breast implants

Breast implant infections can occur due to various risk factors, including capsular contraction. Experts propose diagnostic and management strategies for such problems. Antibiotics may prevent capsular contraction caused by subclinical infection.

SourceThe Lancet_DELETED·JournalThe Lancet Infectious Diseases·DateFeb 1, 2005

Comprehensive study reveals no systemic breast implant dangers

A large-scale study by the University of North Carolina at Chapel Hill found no connection between silicone breast implants and connective tissue diseases. The research, published in the New England Journal of Medicine, included data from 757 studies and analyzed 9 cohort studies, 9 case-control studies, and 2 cross-sectional studies.

SourceUniversity of North Carolina at Chapel Hill·JournalNew England Journal of Medicine·DateMar 14, 2000