Research on autism and neurodevelopment. Covers screening and diagnosis gaps, rising diagnoses among girls, prenatal risks, and genomics.
Researchers flag potential concerns over the impact of social chatbots on neurodiverse people, citing risks of fostering bad habits and reinforcing dysfunctional habits. The technology may relieve social anxiety but can also develop into a form of dependency that negatively impacts actual relationships.
Researchers used brain imaging and machine learning to identify distinct patterns of brain connectivity in people with autism spectrum disorder (ASD), taking into account individual differences. The study reveals that certain brain features are shared across subtypes, while others are unique to specific individuals.
A new UK study confirms autistic people have a reduced life expectancy, but the actual difference may be lower than previously claimed. The research found that autistic men and women without learning disabilities had average estimated life expectancies of 74.6 and 76.8 years respectively.
This study introduces Rigid-Autonomous Phase Sequences (RAPS), which may be responsible for cognitive, sensory-motor, and memory-related challenges in ASD. RAPS can lead to inflexible neural pathways causing difficulties with learning, social communication, and memory.
A novel AI system analyzing brain MRI scans can diagnose autism in children between 24 and 48 months with a 98.5% accuracy rate. This technology enables early detection of autism, potentially leading to improved independence, IQs, and therapeutic outcomes.
A study of 1.3 million Canadian children found a higher risk of autism spectrum disorder in those born to parents with infertility. The research suggests that certain obstetrical and neonatal factors may contribute to this increased risk, highlighting the need for further exploration of these factors in individuals with infertility.
A comprehensive meta-analysis led by Dr. Micheal Sandbank reveals that many low-quality studies are driving intervention recommendations and patient outcomes in early childhood autism care. The study highlights the need for more rigorous research to understand the positive and negative effects of various interventions.
A study of 318,000 children found that those from disadvantaged neighborhoods were more likely to receive an ASD diagnosis. Early intervention and family support resources are needed for these communities
A new USC study reveals that variants of the autism-linked gene SYNGAP1 can disrupt early brain development in the cortex, a region involved in higher-order cognitive functions. The research found that disease-causing variants of SYNGAP1 alter the cells' cytoskeletons and lead to disorganized neural circuits.
Researchers at Trinity College Dublin discovered that autism-induced maternal immune response alters brain development and prevents infantile amnesia. Memories formed during infancy can be permanently reinstated through light-activated neural pathways in adults.
A study found that gastrointestinal and sleep issues may be connected to self-injury and aggression in adolescents diagnosed with profound autism. The researchers discovered a possible connection between these health issues and future challenging behaviors, predicting next-day behavior with over 80% accuracy.
A new study found that sensory differences exacerbate loneliness and poor mental health in Autistic adults, highlighting the need for inclusive social spaces. The research also showed that financial inequalities and lack of employment opportunities contribute to feelings of isolation among Autistic individuals.
A new NIH study examines the impact of the COVID-19 pandemic on adolescents with pre-existing mental, emotional, behavioral, and developmental disabilities. The findings reveal that these teens faced more severe effects, including lower life satisfaction, compared to their peers.
A new study by York University researchers suggests that people with autism are less likely to be affected by the bystander effect, which can lead to inaction in the face of wrongdoing. The findings suggest that neurodivergent individuals can bring unique benefits to workplaces.
A study by Nagoya University found that children with a genetic predisposition to autism spectrum disorder (ASD) used screens for longer periods. Children with attention deficit hyperactivity disorder (ADHD) also increased their screen time as they grew older, suggesting a potential link between genetic risk and excessive screen use.
Researchers from Drexel University's Autism Institute found that most TikTok videos providing information on autism were inaccurate or overgeneralized. Healthcare professionals' content was more likely to include accurate information, while personal experience-based videos were not coded in the study.
A long-term study found that changes in core autism characteristics are related to the development of mental health challenges during elementary school years. Restrictive and repetitive behaviors may help reduce anxiety for autistic individuals.
Brain inflammation in early childhood may prevent specific neurons from maturing fully, leading to conditions like autism spectrum disorders and schizophrenia. Researchers studied post-mortem brain tissue from children with inflammatory conditions or accidents and found that two types of cerebellar neurons were most vulnerable.
A systematic review and meta-analysis found that autistic individuals may produce iconic gestures at a similar rate to, or even more frequently than, neurotypical individuals. This challenges the prevailing belief that autistic individuals tend to use fewer gestures in diagnosis assessments.
Researchers used CRISPR gene editing to study the impact of CHD8 mutations on human cortical neurons. The study found that CHD8 alterations drive molecular and cellular defects in neurons, leading to reduced activity and synaptic communication.
New research from Cold Spring Harbor Laboratory explores how adult brains adapt through critical periods of learning, such as caring for young. MECP2 dysfunction causes neurodevelopmental disorder Rett syndrome, but the study finds that brain circuits can be rapidly rewired in adults.
A new AI-powered app can detect autism in children with high accuracy, capturing a wide range of behavioral characteristics beyond eye movements. The app provides detailed information on which indicators led to its conclusions and why, enabling healthcare providers to make informed decisions.
A groundbreaking study published in JAMA Pediatrics found that 37% of children diagnosed with autism as toddlers no longer meet the criteria for ASD around the age of six. Children with lower adaptive skills are more likely to have ASD persist later in life. The findings underscore the need for ongoing assessments throughout a child's ...
Research from Rutgers University reveals that 1.77% of 16-year-olds in northeastern New Jersey have autism spectrum disorder (ASD), with significant disparities among males, females, and socioeconomic groups.
Researchers discovered protein p53's role in regulating sociability, repetitive behavior, and hippocampus-related learning and memory in mice. Lowering p53 levels led to changes in gene expressions related to behavior, while elevated p53 levels were linked to positive learning outcomes.
A recent study by the University of Cambridge found that autistic individuals are more likely to experience a broad range of chronic physical health conditions across various organ systems. The research highlights the need for closer monitoring and adaptation of healthcare systems to meet the complex needs of autistic people.
A meta-analysis of 71 studies on autism suggests that people with autism may acquire language differently than neurotypical individuals. While interventions aimed at promoting social communication showed no significant language gains, some children with autism learn language without social interaction, such as through digital tablets. ...
A study by researchers at the University of Tokyo found that the presynaptic Ube3a E3 ligase molecule plays a key role in eliminating neural synapses. This discovery offers insights into developmental disorders such as Angelman syndrome and autism spectrum disorders.
Researchers developed a technique called CHOOSE that allows them to test the effect of multiple mutations in parallel and at a single-cell level within human brain organoids. The study identified critical transcriptional changes regulated through common networks, or GRNs, and found that some cell types are more susceptible to autism mu...
Researchers aim to understand the role of gaze in post-stroke reading impairments and develop an employment-specific assessment tool for individuals with autism. The studies may provide major steps towards finding innovative solutions for individuals affected by neglect dyslexia and autism.
Researchers identified serious flaws in NICE-recommended health passports, which may contribute to inaccessible healthcare and early death. They call for new interventions to improve healthcare accessibility and quality for Autistic people, including removing barriers such as lack of staff time and knowledge of Autism.
A study of autistic, non-autistic neurodivergent, and neurotypical adults in the UK reveals unique pressures faced by autistic workers to mask their traits. The findings highlight the importance of creating a supportive work environment that accommodates individual needs.
The EarliPoint device is a first-of-its-kind FDA-authorized tool for early diagnosis of autism spectrum disorder. Early detection can help jumpstart targeted treatment plans, improving outcomes for individuals with autism.
Researchers used objective eye-tracking technology to quantify social visual engagement in young children, revealing its potential as a tool for autism diagnosis. The findings suggest that these measurements can help identify individual levels of social disability and provide insights into verbal and nonverbal abilities.
A new study using eye-tracking technology found that it can accurately predict autism diagnoses, comparable to expert clinical diagnosis. The research suggests potential for earlier diagnosis and assessment of autism in routine practice.
Researchers have developed a new tool that measures children's looking behavior to predict expert clinical diagnosis of autism in children between 16-30 months. The tool provides objective measurements of social disability, verbal ability, and non-verbal learning skills.
Research finds that 75% of boys with fragile X meet criteria for co-occurring autism, but only 31% are identified in community settings. Early diagnosis is crucial to access services improving outcomes and quality of life.
A study reveals implicit and explicit associations between autism and traditional male traits may hinder women's diagnosis and comprehension of autism. The research highlights the need for more inclusive assessment methods.
A new review highlights the current state of the art in autism research, using genetically modified mice to analyze the molecular and physiological mechanisms behind autism. The insular cortex is found to be crucial for emotions, empathy, and motivation in both mice and humans.
The UC Davis MIND Institute is testing the 'Early Start Denver Model' in community agencies, which addresses all areas of development and emphasizes communication and social interaction through everyday activities. The goal is to improve communication skills and daily living skills for autistic children aged 1-4.
A new study found that high-stress caregivers had higher klotho levels and longer telomeres in specific immune cells, which may provide protection against aging. In contrast, low-stress caregivers showed no significant associations between klotho levels and telomere length.
Researchers used machine learning algorithms to analyze brain imaging data and identify changes associated with autism spectrum disorder. The study found that the methodology could determine ASD diagnosis with above 95% accuracy, highlighting potential for improved diagnostic methods.
A new study finds that in-school occupational therapy can create positive learning environments for children with autism by supporting parent-teacher relationships and understanding their unique needs. The therapy helps teachers get to know the child's needs better and facilitate effective communication between parents and schools.
Researchers found that children with autism and macrocephaly exhibit excessive growth of excitatory neurons, while others show a deficit. The study's findings could help doctors diagnose autism and identify potential treatments for specific cases.
Researchers found an abnormal imbalance of excitatory cortical neurons in people with autism spectrum disorder, depending on their head size. The study used human 'mini-brain' models called organoids to recreate the brain development alteration that occurred in patients during fetal development.
A recent study from Drexel University's A.J. Drexel Autism Institute found that only 1.1% of working-age autistic adults are receiving employment services, with stark gaps between Medicaid and Vocational Rehabilitation programs. The research highlights a dire need for policy changes to improve employment services systems in the US.
A new study from ICES and CAMH found that autistic females have an 83% increased risk of self-harm, while autistic males have a 47% greater risk of self-harm events. The study calls for improved mental health support tailored to the needs of autistic individuals.
Researchers found seven potential genes linked to increased autism risk, including rare inherited variations and polygenic scores. Children with language delays had a higher likelihood of inheriting these genes, suggesting a link between genetic risk and language delay.
A new study by Brighton and Sussex Medical School finds that 24% of autistic doctors have attempted suicide, while 77% have considered it. The study highlights the need for workplaces to provide better support and awareness of autistic healthcare professionals.
A new study led by Indiana University School of Medicine researchers shows that primary care clinicians who receive specialized training can make accurate autism diagnoses for over 80 percent of young children referred with developmental delays. The EAE Hub system, a statewide network providing training and collaborative learning, has ...
A University of Ottawa study reveals that a diverse brain's ecosystem is key to maintaining normal function while responding to changes. This concept is inspired by Charles Darwin's idea that biodiversity is crucial for survival, suggesting cell-to-cell diversity helps prevent failures in brain circuits.
Researchers identified significant differences between individuals with CHAMP1 coding mutations and deletions, affecting adaptive functioning skills and severity of symptoms. The study highlights the importance of understanding genetic mechanisms to develop precision medicine approaches for treating CHAMP1 disorder.
A study published in Nature Medicine found that genetic variants associated with autism are present in 4% of those with autism and 1% of the general population. These variants were linked to poorer cognitive performance, lower socioeconomic status, and educational level in undiagnosed individuals.
A mobile app is being tested to help students with disabilities such as autism, down syndrome, and learning disorders. The app, I-Connect, will enable select students to set goals, track progress, and receive prompts to improve their behavior and engagement in class.
Researchers boosted inhibitory interneuron activity in Fragile X mice, reducing hypersensitivity to sensory stimuli. The study found that even young mice with Fragile X had lower PV neuron density and functional decoupling, but treatment restored excitatory neuron function and reduced hypersensitivity.
A new app called START has been shown to accurately identify autistic children in India, with a success rate of 86% for neurodevelopmental disorders and 78% for autism. The low-cost tablet screening tool uses simple games and questions to measure social preference, sensory interests, and motor skills.
A Lehigh University professor has received $4 million in NIH grants to develop an AI-driven approach for precision mental health diagnosis and care. The project aims to identify biomarkers in the brain that can predict treatment response and personalize interventions for patients with depression and other mental disorders.
A Stanford Medicine-led study found that children with autism have impaired memory beyond poor facial recognition, affecting other types of information. The research also revealed distinct brain wiring patterns reflecting these memory challenges.
A study found that people with learning disabilities and autism in the Netherlands chose euthanasia or assisted suicide due to feelings of loneliness, struggling to form friendships, and a lack of resilience. The research highlights the need for individualized support services and an international debate on criteria for euthanasia and ...
New review explores MDXX drugs' potential as novel treatments for ASD, focusing on therapeutic efficacy and safety. The study highlights the importance of balancing these factors to develop effective and relatively safer molecules for ASD treatment.