Articles tagged with Autism
A Tel Aviv University study shows that pressure chamber therapy can improve social skills and reduce neuroinflammation in the autistic brain. The treatment, which involves high-pressure chambers with oxygen enrichment, was found to increase blood and oxygen supply to the brain, leading to improved brain function and social behavior.
Research found that new autism diagnoses tend to cluster within specific NHS service regions, suggesting a possible health service effect on diagnosis rates. This study highlights potential healthcare disparities and the impact of social determinants on autism diagnosis likelihood.
Scientists at OHSU have identified synaptotagmin-3 (SYT3) as a crucial protein for replenishing neurotransmitters between neurons. This discovery sheds new light on the underlying causes of neurological disorders such as epilepsy and autism, and may lead to the development of gene therapies or pharmaceutical approaches targeting SYT3.
A new study developed machine learning models to assess connections among hundreds of clinical variables and predict the likelihood of autism spectrum disorder in young children. The models used de-identified insurance claim data to identify risk factors and quantify their association with autism. This approach has promising potential ...
Researchers have developed brain-like organoids that can be tested experimentally to uncover cellular and molecular causes of autism. The organoids, grown in a dish from human cells, self-organize into layers of cells reminiscent of the cerebral cortex, allowing scientists to study how complex neural structures arise.
Researchers from Aarhus University identified seven genetic variants common to both autism and ADHD, as well as five specific to only one diagnosis. The study suggests a significant overlap in underlying genetic causes and may lead to more precise diagnoses and earlier interventions.
Researchers analyzed data from 145,000 pregnancies and found that antidepressant exposure was not associated with autism spectrum disorder or other neurodevelopmental disorders. The study suggests that antidepressant use during pregnancy may not increase the risk of these conditions in children.
Researchers from the autistic community offer guidelines for using respectful language in autism research, prioritizing the perspectives of autistic individuals. They advocate for a shift towards participatory and co-produced research to reduce power imbalance and ensure autistic involvement.
Research reveals that oligodendrocyte precursor cells (OPCs) contribute to the pruning process, helping shape a healthy brain during early development. OPCs actively engulf synapses, eliminating connections that are no longer needed, and play an intermediary role between external experiences and brain activity.
Researchers found a specific CAPRIN1 gene mutation linked to impaired protein production, leading to autism spectrum disorders, ADHD, language impairments, and muscle weakness. The study also identified similar symptoms in patients with early-onset ataxia and myasthenia.
A new study reveals key differences in dopamine disposal machinery between male and female mice with a rare human genetic variant found in boys with ADHD or ASD. Females exhibit unique behavioral changes, such as increased anxiety and novelty recognition issues, while males display reduced social behavior and perseverative traits.
Researchers at the University of Rochester Medical Center used fMRI to study how the brain processes complex audiovisual speech. The study found that watching a narrator tell a story activates an extensive network of brain regions involved in sensory processing and cognitive functions associated with comprehension. This finding has pot...
Research finds that short-term air pollution exposure increases risk of hospital admission for autistic children, with boys more at risk than girls. The study suggests that reducing air pollution could lower these risks and improve quality of life for affected individuals.
Researchers will investigate racial and ethnic disparities in healthcare services for autistic children in New Jersey. The study aims to understand the social determinants of these disparities and promote health equity among children on the spectrum.
Researchers used a computer model to identify potential candidates for treating ASD, including loperamide, which has shown promise in restoring social behaviors in genetically engineered mice. The study suggests that repurposing existing drugs like loperamide could provide a new treatment option for core autism symptoms.
Researchers found that a common autism screening test consistently excludes more women than men from research studies, creating a 'leaky pipeline' for diagnosis and treatment. This bias is attributed to the test's origins in male-dominated samples, which may not accurately capture female phenotypes.
Researchers studied over 500,000 children born between 1987 and 2010, finding no causal link between maternal infection and autism. However, they did find a weaker link for intellectual disability, suggesting other factors may be at play.
A study by Brigham Young University found that parent-led interventions significantly improve social and communication skills in children with autism spectrum disorder. The meta-analysis of over 50 studies included 2,895 child participants who received about 90 minutes of intervention training each week.
A new study suggests that low-dose ketamine is generally safe and effective in treating clinical symptoms of children diagnosed with ADNP syndrome, a rare neurodevelopmental disorder. The treatment resulted in improvements in social behavior, attention deficit, and hyperactivity, as well as reduced aggression.
Researchers identified critical period plasticity in the amygdala that can be treated with therapeutic intervention at key developmental time points. Early pharmacological intervention was shown effective in reducing fear-learning in the mouse model.
Young people with 22q11.2 Deletion Syndrome show distinct brain activity patterns during sleep, which may influence psychiatric symptoms. These differences are associated with altered connections within and between brain areas.
Researchers found that mothers' higher depressive symptoms did not predict increases in children's behavior problems, including those with autism. The study suggests that maternal depression may have a complex impact on caregiving families.
A new study from the University of East Anglia found that brain regions responding to touch also respond to specific sounds associated with touching objects. This connection may help process sensory information more efficiently and has implications for mental health conditions such as schizophrenia, autism, or anxiety.
Researchers have found that children with autism show significant differences in their pupillary light reflexes, which can be used as a potential screening biomarker. The study demonstrates the parameters of interest that matter for detecting autism and validates earlier findings using monocular technology.
A new study published in JCPP Advances explores the impact of gender differences on autism diagnosis, finding that women's higher emotional needs may mask their autistic traits. The research highlights the importance of improving accurate diagnosis for both men and women, with potential implications for clinical practice.
Researchers have uncovered 60 genes linked to autism spectrum disorder, which may represent a different class of genes associated with core symptoms. The study found that five new genes have a moderate impact on autism characteristics and explain why autism often runs in families.
A new study of over 150,000 participants has identified more than 70 genes strongly associated with autism and over 250 with strong links to the condition. The analysis provides insights into the molecular roots of brain development and neurodiversity.
Researchers analyzed genetic data from nearly 43,000 people with autism and identified a novel group of inherited genes of moderate effect. The study shows that these genes contribute to autism through inherited variants and are associated with other neurodevelopmental disorders.
Researchers at Salk Institute discover a molecule called CGRP that enables neurons to bundle threatening sensory cues into a unified signal, conveying it to the amygdala. The study may lead to new therapies for fear-related disorders such as PTSD and autism.
Researchers discovered that face centering, not saliency, plays a key role in guiding attention to faces in videos as people age. The findings have implications for children's television programming and the diagnosis of autism spectrum disorder.
A new study published in Nature reveals that microglia cells change their molecular state to match neighboring neurons, influencing neural circuit function. The researchers found that different types of cortical neurons recruit specific numbers of microglia, which then adapt to the neuron's environment.
A new study reveals that air pollution and maternal stress during pregnancy can lead to altered brain development and social behavior in male mice, exhibiting autism-like traits. In contrast, female mice are not affected by these environmental factors.
Researchers have identified a novel gene FIBCD1 as likely causative of rare neurodevelopmental disorders. The study found that FIBCD1 is a receptor for ECM 'sugar' components and linked to diseases such as autism, ADHD, schizophrenia, and Alzheimer's.
Researchers used magnetoencephalography to study age-related changes in gamma-band oscillations in the auditory cortex of typically developing children. The results showed that power increased with age and cortical localization changed, indicating an age-related shift in the balance between excitation and inhibition.
A recent study published in Autism Research suggests that autistic adults are only slightly less accurate than non-autistic peers at recognizing human face emotion expressions. The findings contradict the common perception that individuals with autism struggle to understand others' emotions.
Researchers propose a new learning method for individuals with autism, utilizing 'memory flashes' to accelerate learning and improve visual perception capabilities. The study showed significant improvement in both learning speed and generalization of skills, even under new conditions.
Scientists have identified two areas of the auditory cortex specialized to recognize human voice sounds without linguistic meaning. These regions help react to sound cues allowing people to identify characteristics of the person speaking, such as gender, age, and height. This discovery sheds light on neurological disorders affecting vo...
A Rutgers study found that only 47% of autistic children in four New Jersey counties received early intervention programs before 36 months. Income and race-based disparities hindered access to these services. The study highlights the need for universal autism screening and enhanced support for early intervention systems.
Researchers at UCLA have developed a roadmap detailing how stem cells become sensory interneurons, which enable sensations like touch and pain. The study identifies protocols for producing all types of sensory interneurons in the laboratory, paving the way for cell therapies to restore sensation in people with spinal cord injuries.
Researchers found an autism-associated mutation in the Hevin protein results in its retention in the endoplasmic reticulum, activating the unfolded protein response in cells. This disrupts normal brain function, contributing to autism pathogenesis.
A new curriculum called Relationships Decoded shows promise in teaching adults with neurodevelopmental disabilities about healthy romantic relationships and preventing sexual abuse. The program, tested with diverse professionals from California, improves knowledge and understanding of social-sexual relationships.
Researchers found that children with autism process brain waves differently when focused on body movements versus colors, highlighting a key challenge in communication.
A new study has identified neurogliaform cells as key regulators of information flow between brain areas. These cells help separate current perception from past experiences, enabling smooth communication between brain regions.
Researchers at University of Essex found no benefit from oxytocin administration on healthy men's ability to recognize emotions. Computer-based emotional training programs proved more effective in improving emotion recognition and mental health.
Researchers found a higher prevalence of autism spectrum disorder (ASD) in boys than girls, with 410 out of 12,554 children and adolescents reporting an ASD diagnosis. The overall prevalence was estimated at 3.14% for the US population between 2019 and 2020.
New research from UC Santa Cruz shows improvements in autistic adult representation in media and advocacy websites, with a notable increase in adult representations in film and television. However, the study also highlights persistent issues with childlike portrayals and limited attention to intersectionality.
Duke researchers identify DDX3X gene as crucial for neuron formation and brain development, with dosage-dependent defects leading to developmental disabilities. The study sheds light on the molecular mechanisms underlying DDX3X syndrome and related disorders, potentially paving the way for therapies.
Scientists at Tohoku University have identified specific brain wave patterns related to social behavior in mice. These findings provide a unified understanding of brain activity underlying social behavior and its deficits in disease.
A multidisciplinary study by the University of Minnesota found that girls and boys show similar rates of concerns for autism spectrum disorder when screened earlier. The research identified subtle differences in core symptoms but corrected for these biases to reveal a 'high concern' group with an equal sex ratio.
Studies by UC Davis MIND Institute found predictive protein patterns in expecting mothers' blood and links between maternal autoantibodies and higher autistic traits. MAR ASD patterns were associated with autism before birth, with certain patterns predicting autism in previously diagnosed children.
New research from University of South Australia and Flinders University uses retina recordings to identify distinct signals for Attention Deficit Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD), providing a potential biomarker for each condition. Children with ADHD showed higher overall energy, while those with ASD sho...
A study published in the British Journal of Anaesthesia found that fentanyl can induce changes similar to autism-like behaviors in young male and female mice. The research team discovered that fentanyl induces autism-like behaviors via activating the mu-opioid receptor in the anterior cingulate cortex.
A study reveals that valproic acid induces cellular senescence in neuroepithelial cells, leading to developmental defects such as spina bifida, facial alterations, and Autism Spectrum Disorder. The researchers found that a specific molecule, p19Arf, is responsible for this effect.
A new study reveals that drumming can improve the life quality of young people diagnosed with autism by enhancing brain function and behavior. Participants showed fewer signs of hyperactivity, inattention, and repetitive behaviors, demonstrating better control of their emotions.
A Rutgers study analyzing brain stem cells of autism patients found irregularities in early brain development, supporting the concept that ASD arises from poor control of brain cell proliferation. The study discovered that some patients had NPCs producing too many brain cells while others had underproduced cells.
Researchers at USC Dornsife College of Letters, Arts and Sciences have elucidated the structure of a small protein carrying GABA into neurons using cryogenic electron microscopy. This breakthrough could lead to more effective drugs for conditions such as epilepsy, bipolar disorder, schizophrenia, Parkinson's disease, and autism spectru...
Researchers used AI to compare brain images of individuals with Autism Spectrum Disorder to computer-generated simulations, revealing links between brain anatomy and symptoms. The discovery could help understand ASD causes and develop targeted interventions.
Researchers at Texas A&M University College of Medicine have identified a crucial mechanism driving the evolution of the neocortex, leading to increased intelligence and surface area. This breakthrough understanding contributes to insights into developmental deficits linked to autism spectrum disorders and intellectual disabilities.
A new study reveals that combinations of multiple genetic factors determine the risk and severity of symptoms in Autism Spectrum Disorder. Researchers analyzed 37,375 individuals from 11,213 families to understand how rare mutations and common genetic variation contribute to ASD.
A study of nearly 4.5 million children found a potential association between prenatal exposure to antiseizure medications and increased risk of neurodevelopmental disorders. The research suggests that further investigation is needed to confirm these findings.