Articles tagged with Autism
Researchers at Flinders University found that autistic individuals with eating disorders also report higher weight and shape concerns, suggesting a unique combination of symptoms. The study highlights the need for best-practice guidelines to address co-occurring autism and eating disorders in treatment.
Researchers at Massachusetts General Hospital found that 20% of teens and young adults seeking treatment for addiction had elevated social impairment scores, indicating previously unrecognized autistic traits. These individuals were more likely to experience stimulant and opioid use disorders.
Researchers have discovered how genetic variations of the oxytocin receptor affect hormone signaling inside brain cells. The mutated variant is more active and stable than the normal receptor, contradicting previous classifications. This finding provides new starting points for developing targeted therapies for autistic patients.
Researchers at King's College London found that a brain chemical called GABA regulates visual processing in autistic people. Activating GABA targets with the drug arbaclofen improves visual processing, suggesting potential new interventions for autism.
Researchers found molecular signatures of gestational inflammation associated with autism spectrum disorder (ASD) in a large cohort study. Elevated levels of certain immune system molecules at birth are linked to ASD risk, providing potential biomarkers for early screening.
A new study found that implementing a multi-stage screening protocol for autism spectrum disorder in early intervention services can lead to a significant increase in ASD detection, particularly among Spanish-speaking children. The increased rate of ASD detection was nearly twice as high for Spanish-speaking families as for non-Spanish...
Research at University of California - San Diego found that infants with ASD have impaired neural responses to motherese speech, which is crucial for emotional bonding and learning. Typically developing children show stronger brain activation and interest in motherese.
Researchers found that infants with autism symptoms can show significant improvement in just a few months through targeted therapeutic interventions. The studies suggest that bridging the gap between early detection and intervention may significantly reduce the severity of lifelong developmental deviation.
A study by Ann & Robert H Lurie Children's Hospital of Chicago found that cochlear implantation can improve language skills and social engagement in deaf children with autism spectrum disorder. The study reported improved outcomes in 86% of children, including enhanced communication and interaction with families.
Research by University of Texas Health Science Center at San Antonio scientists found that mice missing one copy of the Tbx1 gene exhibit slower cognitive processing. The gene's deletion led to diminished myelin insulation around nerves, impacting signal conduction between brain regions.
Researchers found that astrocytes regulate cognitive flexibility by releasing D-serine and glutamate, which integrates synaptic plasticity. Heterosynaptic long-term depression is mediated by astrocytes, critical for memory modification.
Researchers at Tel Aviv University successfully treated autism in animal models with medical cannabis oil, improving behavioral and biochemical parameters. The treatment showed significant improvement in compulsive and anxious behaviors, and a decrease in the concentration of the arousing neurotransmitter glutamate.
Scientists have discovered a brain protein, CNTNAP2, that quiets overactive brain cells and is at abnormally low levels in children with autism. The protein can be detected in cerebrospinal fluid, making it a potential biomarker for diagnosing autism and treating epilepsy.
Research shows autistic adults on Medicaid have higher odds of co-occurring physical and mental health conditions, including diabetes, obesity, and epilepsy, compared to the general population. Racial and ethnic disparities are also evident, with Black, Hispanic, and Asian adults facing higher odds of certain conditions.
Researchers have identified a key protein in the brain that regulates habituation, a mechanism essential for focus and attention. The study found that a decrease in this protein leads to hypersensitivity and symptoms similar to those seen in Autism Spectrum Disorder.
A study from Children's Hospital of Philadelphia found that only 8% of pediatric healthcare providers feel prepared to assess autistic patients' readiness to drive. The researchers suggest developing resources to prepare providers and families for transportation decisions, which could improve psychosocial, health, and employment outcomes.
Researchers found correlations between brain morphology and sensory characteristics in adults with ASD, suggesting structural changes may cause sensory abnormalities. The study aims to improve diagnosis and treatment options for ASD beyond behavioral indicators.
A study by UC Riverside researchers shows that reactivating the Fmr1 gene in young transgenic mice with Fragile X syndrome eliminates symptoms. This breakthrough treatment offers hope for young children living with FXS and suggests targeting early brain development may be effective.
Researchers have found consistent patterns in GABAergic neuron development between humans and mice, shedding light on the causes of neurodevelopmental disorders like autism and schizophrenia. The study uses single-cell RNA sequencing to create detailed maps of gene expression during human brain development.
Children with autism benefit from group-based weight management and family-centered nutrition education, which improves eating habits and exercise motivation. The program's success rate is higher among families who complete the entire program, indicating its potential as an adjunct or alternative to traditional interventions.
An experimental drug called NAP has been found effective in treating a broad spectrum of symptoms related to autism, intellectual disability, and Alzheimer's disease. Researchers discovered that NAP normalizes brain function in mice modeling ADNP syndrome, a rare disorder linked to these conditions.
Studies in mouse models found that maternal immune activation can alter brain development and lead to autism-like behavioral symptoms. The research also revealed a link between maternal microbiome changes and offspring's susceptibility to intestinal inflammation, with increased IL-17a production by T cells.
Children with autism spectrum disorder should be screened for abnormally high or low cholesterol levels, according to physicians. Research found reduced HDL-C levels in individuals with ASD, indicating a risk factor for cardiovascular disease.
Researchers found damage to a brain part that regulates hyperactivity contributes to both memory issues and seizures in the most common form of epilepsy. This discovery may lead to earlier diagnosis and new treatments for epilepsy and related disorders.
A new model of autism care and treatment prioritizes personalized, stepped approaches tailored to individuals' unique needs throughout their lives. The Lancet Commission calls for global coordination between governments, healthcare providers, and families to reform research, care, and treatment.
Researchers from Drexel University's Autism Institute found that professional development providers with larger, more supportive networks perform better as coaches for teachers of autistic students. They also discovered that coaching support is more important than financial support for performance outcomes.
Researchers discovered that ANK2 variants can affect giant ankyrin-B exclusively or both isoforms simultaneously, altering axon collateral branch formation and targeting. The findings confirm divergent roles of ankyrin-B isoforms and support critical roles in brain development and organization.
Researchers from UC Davis MIND Institute develop a home-based language testing method using telehealth, allowing Spanish-speaking parents to assess their children's language abilities. The study found the parent-led test to be feasible, reliable, and effective in both English and Spanish-speaking groups.
A new study published in Autism highlights the benefits of early diagnosis and treatment for children with autism spectrum disorder (ASD). Children diagnosed before 2.5 years old showed considerable improvements in core social symptoms compared to those diagnosed later in life. Early intervention is critical, emphasizing the need for u...
A new study documents that observable social-communication differences for infants with ASD unfold by 9 months, pointing to a critical window for targeted intervention. Infants with ASD exhibit significantly fewer social and early speech skills than their typically-developing peers at 9 months of age.
Researchers have identified thousands of novel brain-expressed gene isoforms, revealing a complex web of protein production in the brain. The study suggests that genes expressed in the brain may produce far more proteins than previously thought, with potential implications for diseases such as Alzheimer's and schizophrenia.
Abnormalities in brain cells and axons may lead to increased blood flow and more severe symptoms of autism. The study provides insights into the biology of autism spectrum disorder and potential therapeutic targets.
A study found that children with autism tend to have less diverse diets and lower gut microbiome diversity compared to their non-autistic peers. This suggests that dietary preferences may contribute to the development of autism-related traits.
Researchers analyzed a statewide survey in Pennsylvania to identify experiences of autistic individuals and their caregivers across interactions with the criminal justice system. Positive and negative experiences were reported, highlighting an increased risk for male autistic individuals with co-occurring psychiatric diagnoses.
A study has identified a specific protein, PHF3, that plays an important role in transcription and modulates the reading process of DNA. The absence of PHF3 or its binding site SPOC may lead to neuronal production defects, which could be linked to autism and glioblastoma.
A UC Riverside-led study found that maternal transfer of PBDEs causes brain changes and autistic-like behavior in female mice offspring, including reduced social recognition ability and olfactory discrimination. The study suggests that developmental exposure to flame retardants produces ASD-relevant neurochemical and behavioral traits.
Researchers identified 23 genes contributing to congenital heart disease, including 12 previously unknown, using a new algorithm called M-DATA. This method combines genetic data from people with related conditions, increasing the power to identify risk factors and potentially leading to improved treatments.
A study published in Nature Communications identifies a specific form of autism caused by an excessive number of synapses in the cerebral cortex, potentially guiding the development of future treatments. The research found that inhibiting mTOR protein activity can restore synaptic function and connectivity.
A University of Cambridge study found that Jewish autistic children who learn Hebrew as a second language benefit from their cultural identity and community involvement. Parents and teachers rejected outdated professional advice, instead teaching pupils Hebrew to enhance their spiritual and family life.
A new study by Kennedy Krieger Institute found that children with autism spectrum disorder are twice as likely to report suicidal thoughts during routine medical screenings. The study highlights the importance of implementing suicide risk screenings for all children, especially those with neurodevelopmental disorders.
A team of scientists led by Associate Professor Nicola Allen found that astrocyte signaling is directly related to each stage of neuronal development. The researchers determined that astrocytes respond to neurotransmitters produced by neurons to control the timing of signal production, instructing neuronal growth and development.
A Rutgers study found that up to 8% of children in certain New Jersey communities have autism spectrum disorder (ASD), significantly higher than the national average. The study also identified disparities in ASD identification, particularly among Hispanic children.
Researchers at Rutgers University have linked Fragile X and SHANK3 deletion syndrome, both associated with autism and health problems, to walking patterns. The study used motion-sensored sneakers to detect gait problems 15-20 years before clinical diagnosis, offering a potential framework for early intervention.
Researchers found that people's pupils dilate more in response to metaphors than to literal or concrete statements. The study suggests that everyday metaphors, often considered clichés, play a significant role in engaging our brains and conveying richer meaning.
Researchers at Gladstone Institutes found that reducing tau levels impacts both excitatory and inhibitory cells, leading to a reduction in excitation-inhibition ratios. This effect counteracts diseases that cause abnormal increases in this ratio, potentially improving the brain's ability to perform its functions.
A new study found that people with autism spectrum disorder are at a substantially increased risk of self-injury and suicide, with odds over three times higher than in non-autistic individuals. The study identified 31 studies showing statistically significant positive associations between ASD and self-harm.
A UC Davis MIND Institute study suggests telehealth evaluation can help families access care and diagnose autism earlier. The research found that telehealth approaches in the first year of life improved access to care for infants with elevated autism risk, reducing waitlists and parental stress.
A multicenter study found that oxytocin, a hormone used as an autism treatment, had no significant impact on social skills among children with autism. The study of 290 children aged 3-17 showed that oxytocin was safe but ineffective in boosting social abilities.
Researchers developed an algorithm that leverages medical informatics to predict autism spectrum disorder (ASD) diagnoses in young children. The new approach uses diagnostic codes from past doctor's visits to calculate a risk score, identifying which patients are at risk of receiving a confirmed ASD diagnosis.
A recent study published in British Journal of Psychiatry found that adolescents diagnosed with mental health disorders are more likely to be excluded from education and labor market for at least five years. The results highlight the importance of timely treatment and rehabilitation to prevent social exclusion.
Research published in Journal of Autism and Developmental Disorders found that autistic children with difficulties integrating narrative context with facial expressions, leading to inaccurate emotion recognition. This highlights the importance of contextual cues in social exchanges for effectively managing interactions.
A team of researchers at Kennedy Krieger Institute developed a new method to diagnose Autism Spectrum Disorder (ASD) using a single 2D camera. The Computer Assessment of Motor Imitation (CAMI) method provides greater access to patients and shows accurate assessment with 2D technology.
A recent study published in JAMA Network investigated the potential link between epidural analgesia during labor and autism spectrum disorder in children. The research found that administration of epidural analgesia during labor was not significantly associated with autism spectrum disorder in offspring.
The number of autism diagnoses in England has skyrocketed by 787% over the past two decades, driven primarily by increased recognition and improved diagnosis for females. Researchers analyzed GP records and found that the greatest rises were among adults, with females making up most of the increase.
A new study found that unusual visual inspection behavior in infants aged 9 months and older is predictive of a later diagnosis of autism spectrum disorder. This behavior, characterized as an over-focus on objects, was most prominent and present earliest in infants who developed ASD.
Researchers at WVU aim to characterize autism patients' behaviors using behavior-tracking technology. They plan to use artificial intelligence to identify traits associated with ASD, which could lead to more accurate diagnoses and personalized interventions. The study also has the potential to improve early detection in young children.
A new study from the University of Cambridge suggests that autistic adults are less likely to identify as heterosexual and more likely to experience a diverse range of sexual orientations. The research found no differences in likelihood of contracting STIs or age of first sexual activity between autistic and non-autistic individuals.
A parent-led therapy for early signs of autism has significantly reduced the likelihood of an autism diagnosis at age three. The iBASIS-VIPP program uses video-feedback to support social development and unique abilities, resulting in increased parental sensitivity and language development.
A randomized clinical trial found that preemptive intervention for autism spectrum disorder in infants showing early signs significantly reduced ASD symptom severity across childhood. The study also decreased the odds of an ASD diagnosis at 3-years-old.
Researchers analyzed facial asymmetry in 5000 points of 192 parents of autistic children and found they had more asymmetric faces than other adults. This study contributes to understanding the genetic causes of autism, which are known to play a major role in the condition.