Articles tagged with Diabetes
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Researchers at Penn Medicine discovered that maintaining nicotinamide adenine dinucleotide (NAD) levels may protect against kidney disease. NAD supplements were shown to be effective in reversing NAD loss and suppressing inflammation in mouse kidneys, suggesting a potential therapeutic target for kidney disease prevention and treatment.
A trial by researchers at Duke-NUS Medical School found that the Nutri-Grade system encourages consumers to purchase beverages with lower sugar content, especially those with chronic conditions. The study showed a significant increase in purchases of A-rated drinks with 1.5g less sugar per serving.
Richard McIndoe is leading a national research initiative to advance understanding of diabetes and obesity through the National Centers for Metabolic Phenotyping in Live Models of Obesity and Diabetes (MPMOD). The MPMOD initiative provides access to advanced testing services, including bariatric surgery on mice, to enable new insights ...
Research found that pregnancy complications such as preterm delivery, hypertensive disorders, and gestational diabetes are associated with increased risk of mortality. Women who experienced these complications had a higher risk of all-cause mortality, with some complications linked to specific causes of death like cardiovascular diseases.
A new study from British Columbia found that an increase in gestational diabetes rates can be largely attributed to changes in screening practices. After adjusting for screen completion and population factors, diagnoses of gestational diabetes increased by less than one-quarter over a 15-year period.
A new study found that pregnancy complications, such as high blood pressure and preterm delivery, can increase the risk of death in decades following childbirth. The research tracked data from over 46,000 people born between 1959 and 1966, revealing a significant association between these complications and increased mortality rates.
UVA researchers discovered a metabolic pathway that can modulate COVID-19 inflammation, lung recovery, and host metabolic health. They suggest a potentially viable therapeutic agent that may be combined with existing anti-viral agents to treat severe COVID-19 in patients with underlying metabolic disease.
A growing connection between diabetes, oral health, and dementia highlights the importance of dental care and diabetes management as we age. Older adults with both poor oral health and diabetes experience accelerated cognitive decline, emphasizing the need for regular dental visits and adherence to diabetes treatment.
A remote hypertension program, operated by Mass General Brigham, successfully supported patients through the COVID-19 pandemic in achieving their blood pressure goals. Participants who enrolled during the pandemic reached and maintained their goal blood pressures an average of two months earlier than in the pre-pandemic period.
A recent study found that the incidence rates of type 1 and type 2 diabetes continue to rise in children and young adults in the US. Non-Hispanic Black and Hispanic youth were particularly affected, with higher incidence rates compared to non-Hispanic white peers.
A study of nearly 13,000 young US adults found rising diabetes and obesity rates, while hypertension remained stable. The data reveal a high burden of cardiovascular risk factors among this demographic, with Black, Hispanic, and Mexican American individuals disproportionately affected.
A review of dozens of studies found a positive association between sugary drinks and weight gain in both adults and children, with increasing SSB intake linked to greater weight gain over time. Limiting SSB consumption is an effective way to prevent age-related weight gain.
Research reveals obesity increases risk of diabetes and hypertension more significantly in women, with weight loss effective in reducing disease risk. However, merely losing weight is insufficient for reducing dyslipidemia in women, highlighting the need for lifestyle improvement guidance and treatment.
A study found that high-frequency spinal cord stimulation significantly reduced average pain levels by 76%, while improving motor function and sensation. The therapy's long-term safety and potential disease-modifying effects are promising, but further studies are needed to confirm the results.
A new study found that a plant-based low-carbohydrate diet is associated with lower all-cause mortality among people with type 2 diabetes. The study, published in Diabetes Care, analyzed data from over 7,000 participants and found that such diets reduced mortality by 24%.
A study of 135,000 adults found that high cardiovascular health was associated with significantly increased life expectancy free of four major chronic diseases. The disease-free life expectancy was similar between low and other socioeconomic groups among participants with high cardiovascular health.
A new study by the Cleveland Clinic found that high levels of erythritol, a popular artificial sweetener, are associated with an increased risk of heart attack and stroke. Researchers studied over 4,000 people and found those with higher blood erythritol levels were at elevated risk of experiencing a major adverse cardiac event.
A recent study found that adverse pregnancy outcomes are largely driven by pre-pregnancy health issues such as diabetes and hypertension. The rate of hypertensive disorders of pregnancy rose by over 50% during the decade, while the shift in age distribution accounted for less than 2% of that change.
Research finds people with insomnia are 69% more likely to have a heart attack compared to those without the sleep disorder. Insomnia is also associated with an increased risk of heart attacks in people with diabetes and those who get less than five hours of sleep per night.
A study published in Communications Biology reveals that a large portion of an insulin dose may not be effective, providing a tool for developing more precise medications. The discovery could lead to improved treatment outcomes for millions of people worldwide.
A review of 25 years of AI health tech research found that only 24% of studies include patient-reported outcomes, but there has been an increase in recent years. Experts emphasize the importance of integrating patient voices into AI models to support personalized care and prevent digitalization of healthcare.
Researchers at Northwestern University developed a first-of-its-kind small, flexible, stretchable bandage that accelerates healing by delivering electrotherapy directly to the wound site. The bandage healed diabetic ulcers 30% faster than in mice without the bandage.
A recent study found that metformin users had distinct DNA methylation profiles compared to non-users, potentially revealing its role in longevity. The research identified several pathways related to delirium and aging, highlighting the need for further investigation into metformin's mechanism of action.
Researchers reveal Akt2's role in insulin-regulated metabolism, initiating energy production and nucleic acid synthesis. The study provides new insights into metabolic disorders like diabetes, paving the way for targeted therapeutics.
A new study examines the associations between preconception blood glucose levels and the risk of preterm birth. Women with preconception diabetes or prediabetes were found to be at increased risk of preterm birth, with elevated HbA1c levels linked to a higher risk among those without stable healthcare coverage.
A 60-day bed rest study showed that long-term inactivity significantly increases blood sugar levels even with reduced food intake. The study found average blood sugar levels increased by 6% during the day and 10% at night, highlighting the importance of physical activity for metabolic health.
A community co-design model targeting Indigenous diet and diabetes uses a ketogenic eating plan, which aligns with pre-colonisation eating patterns for Australian Indigenous people. The project aims to explore how Indigenous peoples are advantaged by adopting a keto diet and monitor physiological, social, and economic outcomes.
A recent study published in JAMA Network Open found that COVID-19 vaccination significantly reduces the risk of developing new-onset diabetes following an infection. The research suggests a notable benefit of vaccination in protecting against this complication.
A University of Massachusetts Amherst epidemiologist is leading a team to better understand the effects of chronic stress on future health risks. They will examine metabolites in blood samples from a large, racially diverse population to identify potential biomarkers for heart disease, diabetes and cognitive decline.
A smart necklace called SmokeMon tracks a user's every puff and provides valuable insights into their smoking behavior. By analyzing heat signatures, the device can detect when a cigarette is being lit, how much smoke is inhaled, and when the person holds it to their mouth, helping to prevent relapse and improve quit rates.
Researchers found that metabolites associated with the Mediterranean diet may serve as an objective measure to assess adherence among pregnant individuals. The study identified several key metabolites linked to maternal physiology and outcomes, including gestational diabetes and chronic diseases.
Researchers discovered microexons, short DNA sequences that play a vital role in insulin secretion and glucose homeostasis. The study found that genetic variants affecting microexon inclusion are linked to type-2 diabetes risk and fasting blood sugar levels.
A new study found that high physical activity does not offset obesity risk among preteens with high screen time, highlighting the importance of limiting screen time. Parents are advised to encourage physical activities, such as sports and outdoor play, to help combat childhood obesity.
A new study published in the Journal of Clinical Endocrinology & Metabolism found that phthalate exposure may contribute to a higher incidence of diabetes in women. The research, which studied 1,308 women over six years, showed that White women exposed to high levels of certain phthalates had a 30-63% higher chance of developing diabetes.
Researchers at the University of Missouri have designed a soft and breathable material that can be worn on the skin without causing discomfort. The material, made from liquid-metal elastomer composite, has integrated antibacterial and antiviral properties to prevent the formation of harmful pathogens.
A new study by the University of Bristol has found that spironolactone can help preserve the glycocalyx layer on blood vessels in the kidneys, reducing damage from diabetes. This discovery could lead to more effective treatments for diabetic kidney disease without adverse side effects.
A study published in Paediatric and Perinatal Epidemiology found that pregnant individuals living in more walkable neighborhoods have a lower risk of gestational diabetes. The researchers analyzed data from over 109,000 births in New York City and found a significant association between neighborhood walkability and reduced risk of GD.
A new study found that people in highly walkable neighborhoods are more likely to engage in adequate physical activity and have lower BMIs, but the association differs among Black, Hispanic, and Asian populations. The study highlights persistent inequities in physical activity due to systemic racism and policy barriers.
According to hyperfunction theory, menopause is also a disease. Aging is a quasi-programmed disease that can be partially treatable by rapamycin. The author suggests that slowing aging may delay the onset of diseases like prostate cancer, obesity, and hypertension.
Women who experience five major pregnancy complications face an increased risk of ischemic heart disease up to 46 years after delivery. The study found that all major adverse pregnancy outcomes should be recognized as lifelong risk factors for heart disease.
Researchers found that clearance of p16Ink4a-positive cells did not impact β-cell mass, but improved β-cell function and proliferative capacity in a subset of HFD mice. The targeted subpopulation of β-cells is non-proliferative and non-SASP producing.
Researchers found that spinal cord stimulation improved insomnia severity index and Epworth sleepiness scale scores by at least 30% in 39.1% and 28.1% of participants, respectively. The study also established minimally clinical important difference values to gauge treatment success.
A systematic review and meta-analysis of 34 studies found individuals with autism have a higher associated risk of developing diabetes, dyslipidemia, and heart disease. Clinicians should monitor individuals with autism for early signs of cardiometabolic disease and its complications.
Low blood sugar levels trigger an increase in retinal cell proteins, leading to overgrowth of abnormal blood vessels and worsening diabetic eye disease. The study suggests that keeping glucose levels stable is crucial for preventing vision loss in people with diabetes.
A UC Riverside study found that fathers exposed to chemicals in plastics can affect the metabolic health of their offspring for two generations. Paternal DCHP exposure led to high insulin resistance and impaired insulin signaling in F1 offspring, while F2 offspring showed weaker effects.
Researchers have identified serine as a key contributor to peripheral neuropathy in diabetes, a condition that affects approximately half of people with type 1 or type 2 diabetes. Supplementing diabetic mice with serine alleviated neuropathy symptoms, suggesting a potential treatment option.
A survey of primary care clinicians revealed that 44% of patients experience cost-related insulin underuse, with those experiencing poor diabetes control not being more likely to report underuse. Clinicians can address this issue by using empathy to discuss cost barriers and increase the likelihood of changing insulin prescriptions.
A new American Heart Association scientific statement emphasizes the importance of rapid evaluation for TIA, which can lead to full-blown stroke. The statement offers a standardized approach to evaluating people with suspected TIA, including guidance for hospitals in rural areas with limited resources.
A new study conducted at the University of Turku found that maternal gestational diabetes mellitus may have unfavourable effects on the neurodevelopment of 2-year-old children. A healthy diet during pregnancy supports child's neurodevelopment, while higher maternal body fat percentage is associated with weaker cognitive and motor skills.
Higher levels of omega 3 fatty acids found in seafood are associated with a modestly lower risk of chronic kidney disease and slower decline in kidney function. Plant derived omega 3 fatty acids show no association with CKD risk.
A UCSF study suggests people who identify as lesbian, gay, bisexual, transgender, or non-binary may have a higher risk of stroke at a younger age. Non-traditional stroke risks include HIV and syphilis infections.
An international study led by the University of Trento revealed that social interactions play a key role in shaping the composition of our microbiomes. The researchers found that adults acquire microbes through close contact with family members, partners, and friends, while infants acquire them later on at birth.
Researchers have developed an orally administered tablet powered by chemical micromotors that deliver insulin to the colon, reducing blood glucose levels for over five hours. The mini-tablets protected from stomach acid and used hydrogen gas bubbles as micromotors to propel insulin into the bloodstream.
Researchers found that exercise induces a cycle of fatigue and recovery in muscles, paralleled by mitochondrial network rebuilding. Long-term training programs improved middle-aged fitness, while AMPK interventions enhanced exercise capacity during aging.
Researchers at Salk Institute discover thousands of previously unknown microproteins in brown and white fat tissue, finding that one, Gm8773, increases feeding activity in mice. This discovery could lead to the development of a therapeutic to promote weight gain in certain disease situations.
Researchers found that time-restricted eating synchronizes circadian rhythms across multiple systems in mice, activating genes involved in specific diseases like cancer. Nearly 40% of genes in the adrenal gland and pancreas were affected by time-restricted eating, offering guidance for managing diseases.
A study published in Diabetes Research and Clinical Practice found that women with diabetes mellitus are at a higher risk of venous thromboembolism (VTE) than men, particularly during perimenopause. The risk is 1.52 times higher for women with DM compared to those without DM.
Scientists discover a way to train healthy immune cells to acquire tumor cells' skills for accelerating diabetic wound healing. TAMs-educated macrophages promote cell proliferation, resolve inflammation and orchestrate vasculature.
Researchers discovered that MODY3 patients experience hypersecretion of insulin from β cells due to more efficient membrane depolarization. This phenomenon precedes pancreatic β cell failure and can be targeted for prevention or delay with treatments, such as diets or drugs.
A UMass Amherst study reveals that 61% of wellness visits for reproductive-age women (15-49) were with OB-GYNs, while chronic condition patients also relied heavily on these specialists. Key preventive services like pap tests and pelvic exams were more common in OB-GYN settings, whereas lipid testing was rare.