Articles tagged with Diabetes
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GLP1-RA treatment is associated with improvements in quality of life, restrained eating, and emotional eating behavior. The treatment also provides reassurance regarding its psychiatric safety profile.
Researchers at Wayne State University are developing a new treatment to prevent diabetic corneal complications, which can lead to vision loss and poor healing. The project combines two naturally occurring peptides to target inflammation, delayed healing, and nerve degeneration.
Nageotte nodules, previously largely ignored in research, are abundant in sensory ganglia of individuals with diabetic neuropathy and composed mainly of satellite glia and non-myelinating Schwann cells. These clusters may represent a target for drugs that protect nerves or help manage diabetic neuropathy.
A new study has discovered a link between delayed puberty and an increased risk of developing type 2 diabetes in boys. According to the research, adolescent boys who experience delayed puberty are 37% more likely to develop type 2 diabetes in early adulthood, regardless of their weight or socio-economic status.
Researchers discovered a key step in the hepatic ERK pathway that triggers insulin production in response to colonic inflammation caused by obesity. The study reveals a novel role of the gastrointestinal tract in regulating glucose homeostasis.
A cohort study of 12,480 mother-offspring pairs found that pre-pregnancy obesity, gestational diabetes, and hypertensive disorders of pregnancy are associated with increased offspring blood pressure. These risk factors may also promote a faster rate of blood pressure change from age 2 to 18 years.
A new study from the Keck School of Medicine of USC found that children born to mothers with obesity, gestational diabetes, and hypertensive disorders have higher systolic and diastolic blood pressure. The study's findings suggest that early blood pressure interventions could start as early as pregnancy.
A new NIH study found that maternal cardiometabolic health before and during pregnancy is associated with higher blood pressure in children. The study analyzed data from 12,480 mother-child pairs and identified three key risk factors: pre-pregnancy obesity, gestational diabetes, and high blood pressure during pregnancy.
A new approach targeting inflammation may help prevent or slow the progression of Type 1 diabetes by blocking TYK2 protein signaling. Researchers found that inhibiting this protein reduced harmful inflammation in the pancreas and protected insulin-producing beta cells.
A new study by the Physicians Committee for Responsible Medicine found that an online physician-led plant-based nutrition intervention program is practical, cost-effective, and successful at improving patient health. The program led to reductions in diabetes medications, body weight, A1C, and total and LDL cholesterol levels.
A study published in Human Reproduction found that healthy childhood diets are associated with delayed onset of menstruation, independent of body mass index (BMI) or height. The research suggests that a diet high in fruits, vegetables, and whole grains may help reduce the risk of chronic diseases such as diabetes and breast cancer.
Researchers at Pennington Biomedical found that mitochondrial fragmentation can bypass defects in mitophagy to sustain skeletal muscle quality control in patients with Type 2 Diabetes. This adaptation helps maintain mitochondrial function despite impaired mitophagy.
A global analysis reveals significant differences in disease rates, diagnosis, treatment, and death between males and females for three common conditions. Males are more likely to get sick and die from hypertension, diabetes, and HIV/AIDS, while also being less likely to seek medical care.
Z-PULSE Ltd's self-powered wearable health sensors can monitor breathing patterns, bed occupancy, and foetal movements without batteries. The technology aims to improve dementia care and potentially prevent up to 3,400 stillbirths in the UK each year.
A new MRI technique measures a person's 'functional age' of their heart, revealing how unhealthy lifestyles add years to their heart's aging process. This method has the potential to transform heart disease diagnosis and offer a lifeline to millions by catching problems early.
The IOF Advanced Course on Osteoporosis is a comprehensive, 18-hour online training programme designed to equip healthcare professionals with the latest knowledge in osteoporosis prevention, diagnosis, and management. The course aims to promote timely diagnosis and treatment, reduce patient burden, and improve global outcomes.
A new study reveals a concerning rise in type 2 diabetes among depression inpatients in Beijing from 2005 to 2018. Depression and type 2 diabetes co-occurrence is understudied, but the research found 9.13% of depression patients had T2DM, with significant age, sex, and socioeconomic factors linked to elevated risk.
A study by Helmholtz Munich researchers found that GIPR agonism and antagonism decrease body weight and food intake via different mechanisms. GIPR agonists use GABAergic neurons to exert their effect, while antagonists rely on the GLP-1 receptor signal.
The European Society of Endocrinology and the European Hormone and Metabolism Foundation launch a global campaign to raise awareness about hormone balance and its impact on chronic diseases. Small steps can make a big difference in improving hormone health.
Researchers at the University of Tokyo have identified a simple, noninvasive method for assessing blood glucose regulation — an essential factor in diabetes risk. A new algorithm based on continuous glucose monitoring (CGM) data accurately predicts diabetes risk and complications.
A study of over 300,000 adults found that those with diabetes are 25% more likely to lose their health insurance. Insurance instability is particularly concerning for those with complex needs, as many struggle to regain coverage after losing Medicaid or private insurance.
Wild animals studying seals' extreme environments could provide answers to pressing problems in human reproductive health. Seals' unique physiology offers insights into managing gestational diabetes and improving IVF success rates.
Adverse pregnancy outcomes like gestational diabetes and high blood pressure contribute significantly to cardiovascular disease risk factors in midlife. Prioritizing weight management among those considering pregnancy may promote both maternal and future cardiovascular health.
A study by Edith Cowan University found that children born to mothers with gestational diabetes have consistently higher attention-deficient hyperactivity disorder (ADHD) symptoms. Externalising problems, such as hyperactivity and impulsivity, were also more prevalent in these children.
Professor Atsushi Suzuki, Chair of Endocrinology at Fujita Health University School of Medicine, Japan, received the IOF President's Award for his exceptional contributions to IOF. He has shared his expertise as a mentor and engaged member of the Capture the Fracture Governance.
Researchers at Stevens Institute of Technology have created a new approach to personalize nutritional advice by analyzing food types. The data-sparse model accurately predicts individual glycemic responses with no need for blood draws or stool samples.
Researchers at Weill Cornell Medicine found that decreased ceramide levels in blood vessels can cause chronic illnesses. Ceramides regulate blood vessel tone and prevent blood clots, but low levels increase inflammation, high blood pressure, and glucose levels, leading to cardiometabolic conditions.
A study found that migrants experience a 'clear change' in their gut microbiome composition after migration, leading to increased rates of cardiovascular disease. The Amsterdam UMC-led research showed that specific groups of microbes disappear or emerge along the migration axis.
A new study suggests AI-driven smart devices can revolutionize healthcare by detecting cardiac issues early, triggering emergency responses. The Internet of Medical Things (IoMT) technology enables real-time patient monitoring and analysis, improving efficiency and reducing costs.
A novel AI-powered imaging technique, AngioFFR, has been shown to be comparable to conventional FFR assessment in evaluating patients for PCI. The study found that patients treated with AngioFFR-guided PCI had similar clinical outcomes as those treated with IVUS-guided PCI.
A new white paper finds that expanding access to anti-obesity medications can prevent or delay chronic disease by years, providing significant societal benefits. The study estimates a $10 trillion return on investment and 13% annual returns on investment for society.
A cohort study found semaglutide use is associated with a higher risk of nonarteritic anterior ischemic optic neuropathy in people with diabetes. However, the retrospective design limits the study's ability to establish causality, necessitating further research.
A new medical database automatically compiles patient records of obese individuals, offering insights for health promotion and drug development. The J-ORBIT database reveals strong links between obesity and various diseases, including diabetes, hypertension, and coronary heart disease.
A large majority of older Americans believe health insurance – including Medicare – should cover anti-obesity medications. Nearly 37% of respondents met the criteria for overweight and 36% for obesity. Medicare currently covers a drug used for weight management but only in people with diabetes or a history of heart attack or stroke.
A study found that consuming sucralose alters brain activity related to hunger and increases appetite, especially in people with obesity. The sugar substitute changes how the hypothalamus communicates with other brain regions, including those involved in motivation, potentially leading to cravings and eating behavior changes.
A new study finds a positive correlation between microplastic concentration and the prevalence of high blood pressure, diabetes, stroke, but not cancer. Higher microplastic pollution is associated with a higher risk of disease, suggesting a potential link between microplastics and chronic noncommunicable diseases.
A recent study published in The Journal of the American Medical Association found that breast milk from mothers with gestational diabetes has a unique composition that benefits their infant children. Babies of mothers with gestational diabetes experience faster linear growth, lower fat percentages, and reduced weight gain.
A comprehensive study found that people with fatty liver disease have almost twice the mortality rate of the general population. The disease is caused by overweight or obesity and increases the risk of dying from various causes, including liver disease, cancer, cardiovascular disease, and infections.
A team of scientists has successfully developed a novel platform for diabetes treatment utilizing bioink derived from pancreatic tissue and 3D bioprinting technology. The HICA-V platform replicates the structure and function of the human endocrine pancreas, supporting islet maturation and functional enhancement.
A study found no increased risk of suicidal events among adults taking GLP-1 receptor agonists for diabetes or obesity, but continued monitoring is warranted to identify at-risk patients. The findings ease concerns about these potential adverse effects, allowing extended use of GLP-1 RAs.
A study of 733 older female participants found that those with increasing sleepiness had double the risk of stable sleepers. Poor sleep quality in midlife and delayed dream phase are also linked to a higher risk of dementia. The study adds to recent research on the relationship between sleep patterns and dementia.
A new study published in CHEST Critical Care shows that continuous glucose monitors can accurately measure glucose levels during diabetic ketoacidosis, potentially preventing ICU admissions. This tool reduces fingerstick frequency, simplifies management, and improves patient outcomes.
A study published by HKUMed has found that C-reactive protein (CRP) can worsen inflammation in diabetic kidney disease through the Smad3-NLRP3 inflammasome-dependent mechanism. The research suggests that targeting CRP or the Smad3-NLRP3 pathway may provide new treatment options for patients with DKD.
A new study published in Liver International found that a mother's high-fat diet during pregnancy can lead to liver stress and changes in the fetus's bile acid levels. This may be a key factor in the development of metabolic dysfunction-associated steatotic liver disease (MASLD) later in life.
Media professionals can register for ENDO 2025 to discuss groundbreaking research on obesity, diabetes, and more with world-renowned experts. The event features nearly 2,500 abstracts and over 200 sessions, offering a premier global conference in endocrinology research and clinical care.
A national survey found that nearly 90% of Americans believe eating healthy foods is crucial for preventing conditions like obesity and type-2 diabetes. More than half would participate in produce prescriptions or medically tailored meal programs if offered through their healthcare providers.
Researchers at Wayne State University are investigating the mechanisms behind diabetes onset, with a focus on aberrant nuclear signaling and cellular defects. The study aims to identify novel therapeutic targets and test small molecule inhibitors to prevent the establishment of these defects.
The American College of Physicians updates its guidelines recommending SGLT2 inhibitors for chronic kidney disease (CKD) management, regardless of diabetes type. The new guidelines emphasize the importance of tailored care and suggest individualized risk-based approaches to predict kidney failure.
The study found that nearly 1-in-3 young people now live with pediatric onset conditions that significantly affect their lives. Young adults are more likely to develop chronic conditions if they have lower socioeconomic status.
A Japanese study found that CGM devices with low-glucose alerts reduced hypoglycemic incidents and increased confidence among diabetic drivers. The findings suggest that such systems can make driving safer for people with diabetes.
Research in mice found that early-life gut microbes shape insulin-producing cell development and reduce long-term changes in metabolism and diabetes risk. Exposure to a fungus called Candida dubliniensis during infancy may also promote lifelong metabolic health by supporting the growth of insulin-producing cells.
Pacific children are not meeting daily recommended intakes for key micronutrients, leading to associations with childhood obesity and acanthosis nigricans. The study highlights excessive sodium intake across the region, posing cardiovascular health risks.
A new study found that the proportion of visceral fat, rather than the absolute amount, is a stronger predictor of high triglyceride levels and inflammation. Lowering visceral fat proportion during weight loss can lead to better metabolic health outcomes.
A new study published in the European Journal of Preventive Cardiology found that a type of diabetes medication called SGLT2 inhibitors can significantly lower the risk of heart failure and hospital visits related to heart failure in cancer patients. The benefits were particularly promising for breast cancer patients receiving anthracy...
A new drug candidate has been developed to target and eliminate senescent cells in the liver, reducing fat buildup and preventing liver damage. The study demonstrates a safer and more effective approach to treating metabolic dysfunction-associated steatotic liver disease (MASLD) and potentially inhibiting liver cancer development.
Higher perceived discrimination is associated with delayed health care due to nervousness, particularly among younger adults and racial and ethnic minority groups. Better patient-clinician communication can reduce these delays.
Researchers discovered a gene called Plvap enables the body's metabolic shift from burning sugar to fat when fasting. When Plvap is turned off, the liver continues burning sugar, potentially increasing the effectiveness of weight-loss and diabetes medications.
Researchers at Kobe University discovered that gut microbes convert glucose into short-chain fatty acids when fed sugar, highlighting a new symbiotic relationship. This finding could lead to the development of novel therapeutics for regulating gut microbiota and their metabolites.
The study found that the prevalence of adults with diabetes did not significantly change between 2013 and 2023. However, glycemic control among those with diagnosed disease worsened, particularly among young adults. This trend is concerning due to its potential impact on lifetime risk of cardiovascular events.
Researchers found that administration of fish oil reduced insulin resistance and improved blood sugar levels in non-obese rats, reversing a condition similar to type 2 diabetes. The study suggests that omega-3 fatty acids may be a key factor in reducing inflammation and improving glucose metabolism.