Articles tagged with Diabetes
A new study by King's College London found that over 35% of patients without reported diabetes had high blood sugar levels consistent with pre-diabetes. The research uses a simple finger-prick blood test to screen for the condition, which can be done during dental appointments in as little as six minutes.
A new study finds that a novel GLP-1 receptor agonist, Exendin-4-Phe (Ex-Phe-1), preserves glycemic control while reducing malaise and vomiting behaviors in preclinical models. The compound uses biased agonism to selectively activate certain signaling pathways, achieving desired effects without triggering others.
A new American Heart Association scientific statement projects that nearly 6 in 10 US women will have some type of cardiovascular disease by 2050, driven by rising rates in high blood pressure and other health factors. The economic burden is expected to be at least $200 billion annually.
A new study published in Science Advances has shed light on how the body responds to energy demands from exercise, identifying a crucial cell signaling mechanism that could lead to a new treatment for diabetes. The research focuses on Adenosine Monophosphate-Activated Protein Kinase (AMPK), a regulator of energy production, and reveals...
A new study by Harvard T.H. Chan School of Public Health and the Department of Veterans Affairs Boston Healthcare System found that using GLP-1 receptor agonists in combination with adhering to healthy lifestyle habits significantly reduces cardiovascular risk among individuals with type 2 diabetes. The study showed that these two stra...
A ketogenic diet reduced high blood sugar and improved aerobic capacity in mice with hyperglycemia. The diet caused remodeling of their muscles, making them more oxidative and reactive to aerobic exercise. Researchers believe that combining the keto diet with exercise may be key to achieving optimal health benefits.
A survey of 1,998 US adolescents aged 10-19 found nearly 1 in 3 have diabetes or prediabetes. Waist-to-height ratio emerged as the strongest independent predictor of these conditions.
A new study found that adding one avocado and a cup of mango to daily meals and snacks for eight weeks improved vascular function among adults with prediabetes, while also reducing diastolic blood pressure. The Avocado-Mango diet showed significant increases in flow-mediated dilation and nutrient-dense nutrients without changes in calo...
The ESE and ESPE have launched a landmark Joint Clinical Practice Guidance to support structured and effective transition of young people with endocrine conditions. The Guidance provides practical, evidence-based recommendations to ensure continuity, safety and quality of care during this critical phase in a patient's life.
Researchers at Gladstone Institutes discovered that red blood cells act as glucose sponges in low-oxygen conditions, explaining why people living at high altitude have lower diabetes rates. This adaptation fuels efficient oxygen delivery to tissues while lowering blood sugar levels.
Cohort study finds prenatal depression and gestational diabetes independently increase childhood obesity risk, while children exposed to both face the greatest risk, highlighting need for universal screening and targeted interventions.
The American Heart Association reports that millions of US adults with diabetes are unaware they have it, while nine in ten with chronic kidney disease do not know they have it. Regular screening can catch problems early, with approximately 80% of heart attacks and strokes being preventable.
Researchers developed an oxygen-delivering gel to heal chronic wounds that fail to heal for more than a month. The gel conforms to the wound's shape and provides continuous oxygen levels, helping transform nonhealing wounds into normal injuries.
A new study finds salcaprozate sodium may have adverse biological effects on the gut and beyond, including shifts in potentially harmful gut bacteria and elevated inflammatory markers. The research highlights an important gap in understanding the long-term impact of repeated SNAC exposure.
A study comparing biochemical parameters among patients with diabetic nephropathy (DNp), diabetes control (DC), nephropathy control (NC), and healthy controls reveals DNp exhibited the most severe disturbances. DNp showed markedly elevated glycemic indices and impaired renal function, while DC displayed prominent dyslipidemia.
Research finds that SSRIs during pregnancy increase gestational diabetes risk in newborns but lower preterm birth and low birth weight risks. SSRIs also associated with breathing problems and neonatal care needs in newborns.
University of Pittsburgh scientists discovered a way to fight insulin resistance and diabetes by protecting a special type of immune cell in fat tissue. By improving insulin sensitivity in mice, the research reveals a potential new treatment path for type 2 diabetes that could supplement GLP-1 drugs.
A study of 2,700 adults found that South Asian adults in the US had higher rates of prediabetes, type 2 diabetes, and high blood pressure compared to peers from other populations. This suggests the need for earlier screening and risk-factor management to prevent heart disease.
A new global study finds that physical inactivity is a significant driver of diabetes complications, with up to 10% of cases potentially preventable. The research emphasizes the need for tailored approaches to promote physical activity among people with diabetes, particularly addressing social and gender inequalities.
Professor Kazuya Yamagata received the 2025 Erwin von Bâlz Prize Second Prize for his groundbreaking research on pancreatic Ò-cell transcription factors and their role in monogenic diabetes. His work significantly deepens our understanding of β-cell function and diabetes pathophysiology.
A self-regulating, implantable living technology has been developed to offer hope for millions with diabetes. The implant continuously senses blood-glucose levels, produces insulin within itself, and releases the exact amount needed, eliminating the need for daily injections.
A study found that using SGLT2i drugs in patients with gout and type 2 diabetes can lead to lower rates of starting urate-lowering therapy, NSAIDs, and diuretics. This could streamline care and reduce medication burden for these patients.
A new study found that providing financial vouchers to offset medication costs can significantly improve glycemic control among patients with uncontrolled Type 2 diabetes. After six months, participants receiving performance-based incentives saw a clinically substantial reduction in HbA1c levels.
A cohort study of 47,000 adults found that males had a 63% greater risk of all-cause mortality compared to females after adjusting for demographic and behavioral factors. The study suggests intrinsic biological factors, such as sex hormones or immune response, may contribute to these sex differences in mortality.
Scientists at the University of Florida and Linköping University discovered protein markers in umbilical cord blood associated with future insulin-dependent diabetes. The study suggests that these markers can be used to predict type 1 diabetes in early childhood, potentially allowing for targeted interventions and lifestyle changes.
Treatment with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) significantly lowers risks of limb events, cardiovascular events, all-cause mortality, and kidney disease progression compared to dipeptidyl peptidase-4 inhibitors in patients with diabetes. GLP-1 RAs are preferred for secondary prevention in this high-risk population.
Researchers are developing next-generation adaptive insulin delivery systems using machine learning algorithms and ultra-rapid-acting U-500 insulin to personalize glucose control without manual intervention. The project aims to give people with Type 1 Diabetes their time, attention, and peace of mind back.
A new study from the University of Victoria found that higher insulin levels at age 47 predicted younger onsets of hot flashes and night sweats. Insulin may be a stronger predictor of hot flashes when taking other metabolic variables into account, while body mass index (BMI) appeared more closely associated with estrogen level changes.
Researchers found that higher testosterone levels reduced risk, while increased estradiol levels increased cardiovascular risk in male participants. In contrast, women with diabetes showed no significant link between hormone levels and cardiovascular outcomes.
A randomized clinical trial found that a smart speaker-based intervention significantly improved mental distress, quality of life, and diabetes self-care among older adults with type 2 diabetes. This easily implemented self-management strategy may enhance health outcomes in this population.
A research team at Kumamoto University has developed a breakthrough drug-delivery platform using a small-intestine-permeable cyclic peptide, enabling efficient oral delivery of insulin. This approach achieves a pharmacological bioavailability of approximately 33–41% relative to subcutaneous injection.
Researchers developed an AI model called DiaCardia that accurately identifies individuals with prediabetes using only ECG data. The model achieves impressive accuracy and generalizability, even in single-lead ECG data, opening possibilities for home-based screening.
A groundbreaking study reveals B cells' detrimental role in progressing Type 1 diabetes by interfering with regulatory T cells. The findings suggest targeting B cell-Treg interactions could offer new therapeutic strategies for preserving beta cells and improving patient outcomes.
A new review by the Physicians Committee for Responsible Medicine found that ultra-processed plant-based foods like breads and cereals lower type 2 diabetes and hypertension risk. Whole grains and plant-based meat alternatives also have health benefits due to their fiber, micronutrients, and phytochemicals.
A UK-wide childhood screening program for type 1 diabetes has been shown to be effective in detecting early stages of the disease. By identifying children at risk, families can prepare for a potential diagnosis and receive timely treatment, reducing the need for emergency hospitalizations.
Obesity is a chronic health condition associated with harm to health, affecting more than one-third of the US population. A new American Heart Association scientific statement emphasizes socioeconomic and structural barriers to obesity prevention and management.
Research highlights racial-ethnic differences in pregnancy-related high blood pressure risk, with Pacific Islanders and Filipinos more likely to develop a hypertensive disorder. Early identification and treatment can help prevent serious complications for both pregnant individuals and their infants.
Exposure to PFAS is associated with insulin resistance and altered insulin secretion, identifying pregnancy as a key vulnerable period. Gestational diabetes increases the risk of pregnancy complications and long-term health risks for both mother and child.
A recent review of bamboo consumption found promising health benefits, including improved metabolic health, reduced inflammation, and antioxidant activity. However, caution is advised due to potential risks associated with raw or improperly prepared bamboo.
A comprehensive genomic characterisation of E. coli strains isolated from diabetic foot ulcers reveals high diversity and antibiotic resistance. The study provides valuable insights into the specific pathogens involved in diabetic foot disease and suggests potential targets for improved treatment strategies.
The new program combines limb preservation, amputation care, and reconstructive solutions like osseointegration to improve identity, functional outcome, and quality of life for patients. Patients will receive coordinated, personalized, and expert care that supports their recovery and promotes sustained overall health.
A novel photodynamic platform combines antibacterial action, hemostasis and pain relief under natural sunlight, enabling painless, antibiotic-free therapy for infected diabetic wounds. The treatment demonstrates rapid hemostatic capability and a pronounced analgesic effect.
Tufts researchers have developed a method to biosynthetically produce tagatose, a rare sugar with potential health benefits. Tagatose is 92% as sweet as sucrose and has about 60% fewer calories, making it an attractive alternative to conventional sugar substitutes.
A new study reveals that people with an unexpectedly high metabolic BMI have up to a five times higher risk level for diseases such as diabetes and fatty liver. Metabolic BMI is based on advanced metabolomic analyses and identifies obesity-linked changes in metabolism that can be present even at normal weight.
The study reveals that diabetes poses a significant challenge for healthcare systems and economies worldwide. The economic impact of diabetes is substantial, with an estimated global cost of up to $152 trillion, equivalent to 1.7% of GDP, when informal care is factored in.
Scientists at The Wertheim UF Scripps Institute have designed potential diabetes drugs that reprogram insulin-resistant cells into a healthier state while limiting side effect risks. The compounds target PPAR gamma, a master regulator of fat cell and insulin metabolism.
A study of over 12 million US births found a persistent rise in gestational diabetes rates every year since 2016, increasing health risks for mothers and babies. The condition affects all racial and ethnic groups, with American Indian and Pacific Islander populations showing significantly higher rates.
A study led by UC Riverside scientists found that a father's microplastic exposure can trigger metabolic dysfunctions in his offspring, with female offspring being more susceptible. The research used mouse models and found altered sperm small non-coding RNA profiles and increased risk of diabetes in female offspring.
Researchers at Lund University have discovered a cell's protective mechanism against excessive hydrogen peroxide, a key free radical. The study shows that the channel in the cell membrane closes automatically when high concentrations of hydrogen peroxide are detected, preventing damage and cell death.
A systematic review found that pancreatic cancer surgery significantly increases the risk of new-onset diabetes mellitus (NODM), particularly in patients with known risk factors. The study analyzed 45 studies and found an overall incidence of NODM of 24.5%, with a higher rate in those who underwent distal pancreatectomy.
A new study found that gestational diabetes alters the placenta's molecular processes, disrupting gene expression and potentially leading to complications in newborns. The research identified a key protein, SRSF10, that may contribute to these disruptions, offering potential therapeutic targets for preventing pregnancy complications.
The University of Texas at San Antonio has received a $7 million gift commitment from Ed and Linda Whitacre to advance research, student success, and athletics. The gift will fuel groundbreaking discovery in metabolic health and strengthen the institution's role in improving health outcomes for South Texans.
A landmark study published in Nature Metabolism reveals how citrin deficiency, a rare genetic disorder, triggers fat buildup in the liver despite being lean. The research also discovers a hormone that reduces cravings for sweets and alcohol, providing new therapeutic targets for MASLD and fatty liver disease.
Research from King's College London reveals that reversing prediabetes through lowering blood sugar levels significantly reduces the risk of heart problems and death. People who achieved remission had a 58% lower risk of cardiovascular death, while those with normalised glucose levels saw a 42% reduction in major adverse events.
A preliminary study suggests that GLP-1 drugs, used for diabetes and weight loss, may be linked to a lower risk of developing epilepsy. Researchers found an association between the use of these drugs and a reduced risk of epilepsy, with semaglutide showing the strongest correlation.
Pennington Biomedical Research Center launched its first international scientific symposium in Riyadh, Saudi Arabia, exceeding expectations with distinguished audience engagement and new institutional contacts.
Researchers have uncovered a microbial metabolite called trimethylamine (TMA) that can block a key immune pathway and improve blood sugar control. TMA, produced by gut bacteria from dietary choline, targets IRAK4, a protein that triggers inflammation and insulin resistance in diabetic individuals.
A study found that mitochondria in people with type 2 diabetes and fatty liver disease have impaired ability to utilize ketone bodies for energy production. This defect was greater than the overall decline in mitochondrial function, suggesting a potential new target for improving energy metabolism in diabetes.
A multicenter randomized controlled trial demonstrates the advantages of continuous real-time glucose monitoring over finger-prick testing in managing gestational diabetes. The study found that only four percent of women with rt-CGM gave birth to above-average weight children, compared to ten percent in the control group.
A large study found that people with type 1 and type 2 diabetes have a higher risk of sudden cardiac death, particularly in younger adults. The research also showed that sudden cardiac death contributes to shorter life expectancy for those with diabetes.