Articles tagged with Diabetes
Researchers discovered a new pathway that could help people with diabetes avoid dangerous hypoglycemia by restoring the function of delta cells. These cells, previously unknown to play a role in blood sugar regulation, release somatostatin to pause insulin production when necessary.
Researchers found that continuous glucose monitoring metrics correlated with hemoglobin A1c in patients with diabetes, but weakened or disappeared in those with prediabetes and normal glycemic control. CGMs are useful as behavioral tools for people without diabetes, but do not directly reflect longer-term blood sugar control.
A new study reveals a group of immune cells called efferocytic macrophages (eMacs) in the pancreas that can render T cells inactive, protecting insulin-producing beta cells and preventing Type 1 diabetes. The findings offer hope for new therapies for the chronic autoimmune disease.
A study conducted at the University of Eastern Finland found that group-based and online lifestyle counselling can help middle-aged and older men adopt healthier dietary habits, leading to a lower risk of type 2 diabetes. Those with a high genetic risk for type 2 diabetes saw the most significant benefits from fibre-rich diets.
A new study found that around one in seven Black and one in 63 South Asian men in the UK carry a genetic variant known as G6PD deficiency, which can cause delays in type 2 diabetes diagnosis. Men with this deficiency are diagnosed four years later than those without it.
Scientists develop novel experimental screening method to identify highly selective peptides with high therapeutic potential, enabling precise recognition of proteins involved in cancer and diabetes. The technique uses biologically- and chemically-modified bacteriophages to screen up to 1 billion peptides simultaneously.
A binational study found nearly 6 in 10 US adults and 3 in 10 Japanese adults discontinued semaglutide within 12 months of treatment. Patients with established cardiovascular disease and chronic kidney disease had higher discontinuation rates, highlighting the need for alternative treatments.
A pioneering study from George Mason University researcher Raedeh Basiri found that daily mango consumption improves blood glucose control and enhances insulin sensitivity in adults with prediabetes. The high-sugar mango proved more beneficial than a low-sugar granola bar, reducing body fat.
Researchers at the University of Copenhagen discovered two new ciliary proteins that regulate cell communication and may lead to the development of new treatments for chronic diseases. The study found that defective cilia can disrupt signaling in almost all tissues and organs, leading to various diseases.
A study of 92 individuals with type 2 diabetes found that those who overeat due to emotional reasons are less likely to lose clinically significant weight while taking GLP-1 receptor agonists. In contrast, individuals who eat in response to external stimuli tend to respond well to the therapy.
New research finds that GLP-1 receptor agonists (GLP-1RAs) significantly reduce the risk of death and major cardiovascular events in psoriasis patients. GLP-1RAs also show promise in reducing alcohol and substance abuse, with a 65% lower risk of alcohol abuse.
Researchers found that a high-fat diet impairs memory formation in fruit flies by reducing autophagy, a crucial cellular recycling process. This suggests that lifestyle interventions promoting autophagy, such as exercise or intermittent fasting, may improve cognitive decline associated with HFD.
A diet rich in wholegrains, fruits, and vegetables while limiting red meat and sugary drinks may help prevent type 2 diabetes and reduce greenhouse gas emissions. Higher adherence to this planetary health diet was associated with a 32% lower incidence of type 2 diabetes and 18% lower greenhouse emissions.
The European Association for the Study of Diabetes (EASD) has finalized its first evidence-based clinical practice guideline, which prioritizes assessing and managing diabetes distress among adults with type 1 and type 2 diabetes. Key recommendations include routine assessment and management of emotional burden.
A landmark study found gestational diabetes during pregnancy is associated with declines in intellectual function for mothers and higher risks of developmental, behavioural and autism spectrum disorders in children. Mothers with GDM scored 2.47 points lower on cognitive assessments than peers without GDM.
A systematic review of over 9 million pregnancies found that gestational diabetes is associated with cognitive decline in mothers and an increased risk of neurodevelopmental disorders in children. Children born to mothers with gestational diabetes have a 36% higher risk of ADHD and a 56% higher risk of autism spectrum disorders compare...
Two large-scale clinical trials found that a higher dose of semaglutide significantly improves weight loss and related health outcomes in adults with obesity. The study revealed an average weight loss of nearly 19% in those receiving the higher dose, compared to 10% with the standard dose or placebo.
A study reveals how PGC-1α protein and estrogen work together to boost thermogenesis in females, outperforming males. This finding highlights a sex-specific mechanism of energy metabolism and suggests new therapeutic targets for obesity and diabetes prevention.
A four-year NIH grant will support a study of type 1 diabetes, led by Dr. Shuibing Chen at Weill Cornell Medicine. The researchers will investigate the interplay between genetic and environmental triggers using advanced laboratory and computational tools.
Researchers have identified a risk category called 'pre-prediabetes' that occurs years before standard criteria for prediabetes are met. This stage is characterized by severe insulin resistance and measurable cardiovascular disease, highlighting the need for early detection and treatment.
The 2025 Childhood Obesity Conference, hosted by Pennington Biomedical's Greaux Health initiative, aims to educate healthcare providers and promote healthier futures for Louisiana's children through cutting-edge research and evidence-based strategies. Participants can earn up to 7.5 CMEs and gain practical tools to support healthier fu...
A recent study found that green tea extract improved glucose sensitivity and insulin resistance in obese mice, preserving muscle morphology. The treatment reduced body weight by up to 30% and increased the expression of genes related to glucose metabolism, suggesting a selective effect on excess body fat.
Researchers create peptide hydrogel that controls drug release, improving treatment adherence and efficacy for conditions like tuberculosis and diabetes. The SABER platform uses reversible chemical bonds to slow down drug release, offering a promising solution for precise delivery.
The Society of Interventional Radiology has published new practice guidance for creating percutaneous arteriovenous fistulas for dialysis access. The guidance emphasizes the importance of interventional radiologists in providing durable hemodialysis access to improve patient outcomes.
A large portion of people with diabetes remain undiagnosed or receive suboptimal care. The study found that 44% of those aged 15 and older with diabetes are unaware of their condition, with substantial regional diagnosis and treatment disparities.
IRB Barcelona researchers discovered a new strategy to combat obesity by activating brown fat, boosting energy expenditure and improving metabolic health. The approach, driven by Neuritin 1 protein, increased energy burning without affecting food intake or physical activity.
Researchers found 22 previously unknown genetic variants associated with type 2 diabetes by considering participants' hormone levels. The analysis suggests that sex hormone levels interact with genes to increase the risk of developing the disease.
People with hepatitis B immunity induced by vaccination have a lower risk of developing diabetes of any kind. The study found that higher HBsAb levels were associated with greater reductions in diabetes risk.
Researchers found that diabetes directly affects the heart's structure and energy production in humans for the first time. Diabetes causes distinct molecular changes to heart cells and structural changes to the muscle, particularly in patients with ischaemic cardiomyopathy.
A cross-sectional study found associations between HbA1c levels and modern diabetes technologies and insulin accessibility. Efforts to ensure universal accessibility are crucial to reduce global inequities in glycemic outcomes for children with type 1 diabetes.
Researchers at Wayne State University are developing an ultra-rapid insulin designed to mimic the human pancreas, aiming to improve glycemic control and reduce disease management burden. The project has the potential to create fully automated systems, enabling patients to manage their condition with fewer interruptions.
Researchers at Boston University School of Medicine found that tiny particles in the blood, known as exosomes, can reprogram immune cells inside tumors making them weaker and allowing the cancer to grow and spread more easily. The study provides new insights into why people with type 2 diabetes have worse breast cancer outcomes.
The Pennington Biomedical Research Center has opened a new Endocrinology and Diabetes Clinic in Baton Rouge, providing specialized care for patients managing diabetes and endocrine disorders. The clinic is led by Dr. Timothy Gilbert, who brings nearly 20 years of private practice experience to the region.
A Mediterranean-style diet, along with reduced caloric intake and moderate physical activity, has been shown to lower the risk of type 2 diabetes by 31%. The study found that participants in the intervention group lost an average of 3.3 kilograms and reduced their waist circumference by 3.6 centimeters.
A new national survey of over 580 school nurses and healthcare providers has identified critical barriers to implementing the ADA's DMMP in schools. The updated DMMP aims to streamline communication and provide greater customization for modern devices, enhancing safety, equity, and health outcomes for students with diabetes.
A large Spanish multicenter clinical trial found that a calorie-reduced Mediterranean diet combined with moderate exercise reduces type 2 diabetes risk by 31%. The intervention group also lost weight and reduced waist circumference, preventing approximately three in every 100 participants from developing the disease.
Researchers found that a molecule produced by gut bacteria can cause inflammation, scarring and fibrosis in the kidneys, a major complication of diabetes. Corisin, a small peptide, attaches to albumin in the blood and targets the delicate kidney structures, accelerating aging and cell death.
Research highlights preventable harms of intensive diabetes and hypertension treatment in frail older adults, calling for personalized care approaches that prioritize patient safety. Guidelines recommend cautious individualized care, but complications remain alarmingly common.
Researchers have created a wearable system that combines drug delivery, electrical stimulation, and continuous monitoring to treat diabetic foot ulcers. The microneedle platform anchors securely into the skin and adjusts therapy in real-time to prevent severe tissue damage.
Researchers developed a first-trimester blood test that accurately predicts gestational diabetes risk, using just seven biomarkers. The test's strong ability to distinguish high-risk from low-risk pregnancies could enable early interventions and reduce long-term health burdens.
Scientists have developed a monoclonal antibody to combat life-threatening inflammatory diseases like sepsis and ARDS. The antibody shows promise in blocking the immune system's hyperactive response and restoring healthy function without unwanted side effects.
Experts recommend SGLT-2 and GLP-1 diabetes drugs for adults with high cardiovascular and kidney risk, but not those at low risk. The guidelines emphasize weight loss alongside medication for adults with obesity.
An ethnobotanist from the Pataxó Hã-Hã-Hãi Indigenous Land in Brazil has revived ancestral healing knowledge to treat diseases like parasitic worms, diabetes, and hypertension. He discovered 43 medicinal plants used for these diseases, with 79% consistent with recent scientific literature.
Researchers at Cornell University developed an implant system that can treat Type 1 diabetes by supplying extra oxygen to densely packed insulin-secreting cells, enabling long-term treatment for chronic diseases. The system could also potentially provide treatment for other autoimmune diseases.
Researchers at City of Hope are investigating how wearable devices can detect and prevent long-term health risks in childhood cancer survivors. Yue Liao, a UT Arlington expert, is contributing to the review article, highlighting the potential of digital health tools to monitor daily fluctuations and behavior.
A rapid increase in diabetes technology adoption led to improved glycemic control among type 1 diabetes patients, yet racial and socioeconomic disparities persisted. Notable racial and ethnic differences grew over time, highlighting the need for targeted interventions.
Researchers at the Salk Institute have identified dozens of microproteins that play a crucial role in regulating fat cell proliferation and lipid accumulation. This breakthrough discovery offers new potential drug targets for treating obesity and metabolic disorders, building on recent advances in CRISPR gene editing technologies.
Younger adults with prediabetes are at increased risk of mortality, highlighting the importance of age-specific interventions and targeted prevention programs. Lifestyle behaviors and limited health care access contribute to this risk, underscoring the need for flexible and accessible diabetes prevention options.
A new study found that consuming three servings of French fries weekly increased the risk of developing type 2 diabetes by 20%. In contrast, baked, boiled, or mashed potatoes were not significantly associated with T2D risk. Swapping any form of potato for whole grains may lower the risk of T2D, with a 4% reduction in risk estimated.
A study of over 452,000 adults found that metformin users had significantly lower risks of dementia and all-cause death compared to non-users. The benefits were seen across all categories of overweight and obesity, with reduced risks of up to 26% for death.
A study reveals faulty genomic regulation and RNA scrambling as key contributors to type-2 diabetes. Deleting HNF1A in β-cells affects the expression of over 100 genes, many involved in insulin transport and release.
A modified version of the DASH diet has been shown to lower glucose levels and improve blood glucose control in adults with type 2 diabetes. The DASH4D diet, which is similar to the original DASH diet but lower in carbohydrates and higher in unsaturated fats, helped participants with type 2 diabetes control their glucose levels.
A landmark study found that adopting five healthy lifestyle habits—healthy weight, no smoking, regular physical activity, high-quality diet, and moderate alcohol intake—can reduce cardiovascular disease risk by up to 86% in women with a history of gestational diabetes. Women who followed all these habits had no cardiovascular events ov...
A new study from University of California San Diego found that frequent standing breaks can lower diastolic blood pressure in postmenopausal women. Women who increased daily sit-to-stand movements saw measurable improvements in blood pressure, with an average decrease of 2.24 mmHg within three months.
A new study found that mothers living in resource-poor neighborhoods in Arizona were 20% more likely to develop gestational diabetes mellitus compared to those in less deprived areas. The study also highlighted the high incidence of GDM among Native Americans, who had a rate nearly double the overall population.
A technology expert predicts AI-based medicine will revolutionise care for Alzheimer’s and diabetes, but access must be made available to all patients. The author highlights key innovations such as diagnostic imaging and surgical robots that will aid in more accurate diagnoses and treatments.
A new AI model uses a combination of data, including real-time glucose levels from wearable monitors, to provide a more nuanced view of diabetes risk. It flags early signs of diabetes risk that standard HbA1c tests may miss.
A UNLV study uses an mRNA cocktail to selectively route to the pancreas, reducing the risk of immune responses and side effects. The breakthrough offers new hope for treating pancreas-related diseases, including cancer and diabetes.
A recent study published in Nature Communications has found that specific cell subtypes are more prone to developing into diabetes. By tracking these subtypes over time, researchers can better understand how they drift over time or under different conditions. The findings hold promise for potential prevention and treatment strategies.
A new study suggests that marbling of fat inside muscles is a strong indicator of poor health, including obesity, Type 2 diabetes, and neuromuscular disorders. The research found that intramuscular fat acts as a physical barrier obstructing muscle healing and regeneration.