Dr. Raj Ladher of NCBS receives grant to study protein protocadherin-15 and its role in hearing loss. The funds will aid in understanding how modified protocadherin-15 affects hair cell response to sound, which could lead to treatment development for hearing loss.
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Researchers found Mindfulness based Cognitive Therapy (MBCT) significantly reduces tinnitus severity compared to relaxation-based treatments. MBCT teaches patients to 'allow' and 'accept' tinnitus, leading to a less intrusive experience.
Researchers have found that giving sodium thiosulphate after chemotherapy reduces hearing loss in children treated for hepatoblastoma, a childhood liver cancer, by nearly 50%. The treatment is a major step forward in minimizing long-term side effects and offers hope to families affected by the debilitating condition.
A study from Ohio State University has found that young people with subtle hearing loss are putting demands on their brains that could be preserved until later in life. This early hearing loss could lead to cognitive decline and an increased risk of dementia.
Researchers from Brigham and Women's Hospital found that eating a healthy diet is associated with a lower risk of acquired hearing loss in women. Those who followed the Alternate Mediterranean diet or Dietary Approaches to Stop Hypertension had a 30% lower risk of moderate or worse hearing loss.
Researchers have identified a potential treatment for noise-induced hearing loss, where osmotic stabilization of fluid volume in the inner ear after exposure can prevent subsequent hearing loss. Increasing solute concentration in perilymph reduces endolymph volume and helps preserve synaptic ribbons on hair cells.
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A new approach to hearing assessment has been developed and validated, focusing on whether public safety professionals can perform 'hearing-critical' job tasks in specific noise environments. The method takes into account real-world noise environments and provides an objective means of occupational hearing screening.
A new study finds that older adults with severe hearing loss who use hearing aids are less likely to visit the hospital or emergency room, despite high costs of the devices themselves. The association is significant, even considering factors such as income and education level.
A large study found that smoking is associated with an increased risk of hearing loss, particularly high-frequency hearing loss. The risk decreased after quitting smoking within 5 years. Researchers analyzed data from over 50,000 participants and adjusted for factors like occupational noise exposure.
Researchers discovered that inhibiting CDK2 protects mice and rats from noise- or drug-induced hearing loss. Kenpaullone, a CDK2 inhibitor, shows significant clinical potential in treating noise-induced hearing loss.
A preliminary study has found an association between central hearing loss and mild cognitive impairment in some people. Researchers discovered that individuals with central hearing loss were twice as likely to have mild cognitive impairment compared to those without hearing loss.
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A study of 348 preschoolers who survived cardiac surgery found hearing loss in 21.6% of children, associated with language and cognitive problems by age four. Researchers recommend early hearing evaluations between 24-30 months to increase timely medical intervention.
Young adults who were undernourished as preschool children were nearly twice as likely to suffer from hearing loss. Nutritional interventions in South Asia could help prevent hearing loss, a condition affecting an estimated 116 million young people.
A new noninvasive approach to treat tinnitus has shown promising results in a double-blind study, alleviating symptoms in 20% of participants. The therapy involves alternating audio and somatosensory stimulation, delivered through headphones and mild pulses on the neck or cheek.
Researchers have developed a new approach to treating tinnitus by targeting unruly nerve activity in the brain with precisely timed sound and skin stimulation. Human participants reported improved quality of life after four weeks of daily device use, while sham treatment did not produce similar effects.
A new NIH-funded study aims to examine the association between environmental exposure to lead and cadmium and hearing loss in Detroit firefighters. The research project will test the hearing of 200 firefighters and assess genetic factors and bone lead levels.
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Researchers used fMRI to study neurofeedback training's potential in treating tinnitus, finding a significant relationship between controlling the primary auditory cortex and attentional processes. The training involved participants focusing away from sound to decrease brain activity.
A new approach to detecting dyslexia has been developed by associating auditory processing in children with their reading skills. The study found that children who had difficulty processing low-frequency sounds were more likely to have reading problems and may be at risk of developing dyslexia.
A Penn study reveals that ESRP1 gene mutations contribute to early hearing loss in humans, highlighting a critical molecular pathway involved in auditory development. The discovery opens up possibilities for new therapeutic approaches.
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Researchers tested participants' hearing and speech abilities before and after extreme noise exposure to determine if it caused permanent damage. The study found temporary changes in some functional tests but no evidence of hidden hearing loss.
A recent study has found that natural killer cells play an important role in protecting against CMV-induced hearing loss in mice. The interaction between NK cells and the viral protein m157 is crucial in preventing hearing loss, with mice lacking this interaction being more susceptible to hearing loss.
A recent study has found no evidence of auditory nerve injury or permanent hearing difficulties in young adults after attending a loud event. The research suggests that traditional hearing tests may not detect hidden hearing loss caused by recreational noise, highlighting the need for alternative testing methods.
Researchers test antiviral therapy to halt progressive hearing loss in children with confirmed CMV infection, finding that treatment may prevent further damage and improve outcomes for those infected.
Researchers found that chronic tinnitus is associated with changes in certain networks in the brain, leading to increased attention and reduced rest. The study provides hope for future treatment options and validates patients' experiences.
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Researchers found that serotonin can make neurons hyperactive and hypersensitive to stimuli in the brain, worsening tinnitus. The study has implications for treating anxiety or depression with selective serotonin reuptake inhibitors (SSRIs), which may compound feelings of anxiety in patients with tinnitus.
The federal government does not require Medicaid to cover hearing aids, resulting in inconsistent coverage across states. Inconsistencies exist due to varying guidelines, with some states requiring moderate or greater hearing loss for coverage.
A comprehensive global effort is needed to address the growing burden of hearing loss, with half a billion people affected worldwide. The proposal emphasizes increased access to screenings, treatments, and preventive measures, as well as low-cost interventions using smartphones and telemedicine.
Researchers found that three of the OTC devices offered improvements in speech understanding comparable to a conventional hearing aid. However, one device demonstrated little improvement and another had worse results. The study's findings support efforts to make hearing aids more accessible through over-the-counter sales.
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Researchers discovered conductive hearing loss is the most common type of hearing loss in Alagille Syndrome patients, affecting nearly one-third of all ears. CT scans revealed structural defects in the middle ear that vary in effect on hearing.
Women who undergo postmenopausal hormone therapy may be at higher risk of hearing loss, according to a new study. The risk tends to increase with longer duration of use and is associated with older age at natural menopause.
A review of medical literature by NYU researchers found that only 23.9% of studies on doctor-patient communication mentioned hearing loss, highlighting a significant gap in understanding its impact on care. The study suggests that simple strategies can mitigate the negative effects of hearing loss on patient communication.
Research reveals that hearing loss is a highly prevalent and important factor in communication between healthcare professionals and older adults, but it's largely overlooked. Studies show that offering hearing assistance can improve patients' understanding.
A Swedish twin registry study reveals that bilateral tinnitus has a strong genetic component, especially in men, while unilateral tinnitus is more influenced by environmental factors. The findings have important clinical implications for diagnosis, treatment, and public health.
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Researchers develop protocol to efficiently grow cochlear progenitor cells into large colonies with high capacity for differentiation, offering potential treatment for hearing loss. The approach, leveraging Wnt signaling and histone deacetylase inhibition, enables regeneration of sensory hair cells in multiple mammalian species.
Researchers from Brigham and Women's Hospital and Massachusetts Institute of Technology have developed a method to grow large quantities of inner ear progenitor cells that convert into functional hair cells. The technique shows potential as a therapy for patients with hearing loss, particularly those caused by loud noises or toxic drugs.
Researchers discovered that disruption in Schwann cells, which make myelin, leads to hidden hearing loss. This finding may help diagnose and treat the condition, which affects individuals exposed to high levels of noise. The discovery could lead to new treatments for hidden hearing loss.
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A new study by University of Utah researchers found that a state-wide screening program led to increased early identification of infants with hearing loss due to congenital CMV. The law also provided funds for educational campaigns, which is important given the virus's prevalence.
Researchers at Wayne State University have developed a novel diagnostic tool to identify tinnitus in animals, providing a significant breakthrough in understanding the underlying mechanisms of this condition. The new method, which uses a conditioned licking suppression behavioral test, enables researchers to assess tinnitus onset, seve...
Dutch clinicians have developed a personalized dosing strategy for treating multidrug-resistant tuberculosis, reducing hearing loss from 40% to 10%. By monitoring drug concentrations and effectiveness, they were able to decrease doses without compromising efficacy.
Researchers at UConn School of Medicine developed a new hearing test to identify binaural processing deficits in individuals with normal or near-normal audiograms. The study found that listeners with essentially normal clinical hearing test results may exhibit substantial deficits in binaural processing.
A Brigham and Women's Hospital study found that using ibuprofen or acetaminophen for 6 years or more increases the risk of hearing loss in women. The research analyzed data from over 54,000 women and found a modest increase in risk, with approximately 5.5% of hearing loss potentially due to pain reliever use.
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A randomized, controlled study found that sodium thiosulfate prevents cisplatin-induced hearing loss in children and adolescents with cancer, with a 29% reduction in hearing loss compared to cisplatin alone. The greatest benefit was seen in children younger than 5 years old.
Adding higher frequencies to the American Academy of Pediatrics hearing test protocol helps detect adolescent hearing loss. Early detection enables modification of behavior to prevent continued damage. The study found that young adults with mild hearing loss may exhibit reading, emotional, or socialization problems.
Researchers used electronic health records and genome sequences to identify two genetic variations linked to age-related hearing impairment. The study found novel variations near the ISG20 gene and within TRIOBP, a gene previously associated with another type of hearing loss.
A study published in PLOS Genetics identified two genetic variations linked to age-related hearing impairment, shedding light on the disorder's biological basis. The research used a large cohort of patients' electronic medical records and genome sequences to discover these genetic links.
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Researchers developed an artificial basilar membrane that mimics human cochlear function using frictional electricity, addressing major issues with existing implants. The technology proves effective in restoring impaired animals' listening capabilities.
A study found that universal newborn screening for congenital cytomegalovirus (cCMV) infection is generally associated with cost savings or is essentially cost-neutral, satisfying criteria for newborn screening. The cost of identifying one case of cCMV was estimated to be between $566 and $10,000.
Scientists have identified the GLAST gene as a potential protector against tinnitus, a condition characterized by ringing in the ears. The study found that mice with normal GLAST function were less prone to developing tinnitus when exposed to toxic substances.
Researchers have identified a gene associated with age-related hearing loss in mice, which could lead to investigations into the equivalent human gene and potential screening programs to predict susceptibility. This discovery may ultimately inform treatment development or timing of interventions.
Scientists have pinpointed the specific part of the brain that helps older adults differentiate speech sounds in background noise. The study found that the speech motor area of the frontal lobe steps in to compensate for hearing loss, enabling seniors to identify speech embedded in noise.
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A study published in Scientific Reports found that almost all teenagers engage in risky listening habits, leading to persistent tinnitus and heightened sensitivity to loud sounds. The researchers warn of a major public health challenge as the prevalence of hearing damage is expected to increase.
A study from the University of Utah finds that older Americans with hearing loss have more trouble understanding British accents when there is background noise. The study also explores how transgender women can adopt a clearer speaking style to sound more feminine and how fast-talking affects speech intelligibility.
Cisplatin kills rapidly dividing cancer cells but also causes permanent hearing loss due to damage to sensory hair cells in the inner ear. Individuals with Cockayne syndrome, a genetic disorder affecting DNA repair, are more susceptible to this side effect.
Research reveals half of farmed fish have hearing loss, which affects their survival in the wild, leading to compromised welfare standards. The study's findings suggest that deformed earbones are larger, lighter, and more brittle, resulting in significant hearing sensitivity loss.
A study at Columbia University Irving Medical Center found that using a hearing aid significantly improves cognitive test scores in older adults with hearing loss. The researchers suggest that this may help prevent or slow the development of dementia.
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Researchers detected frequency-following responses coming from the auditory cortex, in addition to known sub-cortical generators, using magnetoencephalography (MEG) technology. This discovery will inform further research into neuroplasticity and its potential to improve auditory processing.
A team of researchers at the University of Pittsburgh School of Medicine has designed a more effective version of an FDA-approved epilepsy drug with the potential for fewer side effects. The experimental agent could also prove to be a treatment for tinnitus and other disorders caused by volatile neural signaling.
Case reports published in The Journal of the American Osteopathic Association document improvements in concussion-related symptoms following osteopathic manipulative treatment. These treatments can help restore cerebrospinal fluid flow to promote healing and alleviate symptoms such as headache, nausea, dizziness, and tinnitus.
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Researchers are focusing on the key hormone 'aldosterone' and developing unique sounds to treat age-related hearing loss (ARHL). Studies will investigate its effects on mice and humans, with goals of slowing or preventing ARHL progression through hormonal intervention and brain training.
Researchers at Columbia University are reengineering and simplifying music to make it more enjoyable for listeners with cochlear implants. By analyzing which parts of music are most important for listener enjoyment, they aim to develop software that can take original pieces and reconfigure them or allow users to engineer their own music.