Articles tagged with Hypertension
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New research reveals that exposure to loud noise can lead to high blood pressure and potentially cancer-related DNA damage in mice. Healthy mice exposed to aircraft noise were more likely to develop high blood pressure.
A novel protein, thrombospondin-1 (Thbs1), plays a crucial role in mechanotransduction in blood vessel walls, enabling cells to adapt to changing mechanical forces. The absence of Thbs1 can lead to weakened blood vessel walls, increasing the risk of cardiovascular disease.
A study examined the association between renin-angiotensin system inhibitors and COVID-19 severity, finding no significant link to increased risk of death or severe illness. However, some studies suggest that these medications may exacerbate respiratory symptoms in patients with underlying hypertension.
Research team finds that high-altitude adaptations in the Himalayas may lower risk for hypertension and diabetes-associated anemia. The study, led by Katherine Wander of Binghamton University, found that a Tibetan-descended population living in Southwest China had lower rates of these conditions compared to low-altitude Han populations.
A Finnish study found associations between hypertensive pregnancy disorders, including preeclampsia, and childhood mental disorders. Maternal preeclampsia was associated with a 66% higher risk of mental disorders in offspring, while severe preeclampsia increased the risk by two-fold.
A new study shows that people with high blood pressure and reverse dipping may have small areas in the brain damaged from vascular disease, leading to memory problems. Those with high blood pressure and reverse dipping also had lower scores on a memory test, with average scores of about 33 compared to 40 for those without these conditi...
A Canadian study found that nearly a quarter of adults suffer from hypertension, with a notable decline in awareness, treatment, and control rates, particularly among women. The findings highlight the need for urgent re-engagement on blood pressure treatment and control to combat preventable deaths and disability.
A larger thigh circumference may be associated with lower blood pressure and a reduced risk of heart disease in people with obesity. Thigh circumference could potentially be used as an indicator for earlier detection and prevention of high blood pressure and related complications.
A new study published by Oxford University Press USA found that mat Pilates training significantly reduces arterial stiffness and blood pressure in young obese women with elevated blood pressure. The study, which included 12 weeks of mat Pilates training, also found a decrease in body fatness.
Recent research suggests that ACE inhibitors and angiotensin receptor blockers can have a beneficial effect on COVID-19 outcomes for hypertensive patients. A review of over 60 published studies found no evidence to support concerns about these drugs increasing the risk of infection or disease severity.
Patients with untreated high blood pressure experienced statistically significant reductions in average blood pressure over 24 hours following renal denervation. The procedure offered an effective alternative approach to traditional medications, lowering blood pressure throughout the day and early morning periods.
A new study published in the Journal of the Endocrine Society found that chemicals such as bisphenol A (BPA) substitutes can affect fetal development and lead to hypertension in later life. The research, conducted on pregnant rats, suggests that even low-dose exposure to these chemicals can impact blood pressure later in life.
A study published in the American Heart Association journal Hypertension finds no credible evidence that ARBs increase COVID-19 susceptibility. Discontinuing these medications would pose significant health risks for patients with hypertension and chronic kidney disease.
Research shows female mice accumulate more liver fat than males but are better at using it up, potentially benefiting women's health. Fasting may be beneficial for women specifically due to its impact on liver health.
A new study found that cumulative doses of oral steroids are associated with increased hypertension, affecting over 24,000 adults with chronic inflammatory diseases. The researchers recommend closer monitoring of blood pressure in these patients.
Rates of deaths related to hypertension have risen sharply across the US, with a 72% increase in rural areas and a 20% increase in urban areas. High blood pressure can cause damage to arteries and lead to events such as heart attacks or strokes, emphasizing the importance of taking it seriously.
A study of 329 female college athletes found nearly half had higher than normal blood pressure levels, with 61% classified as elevated. The research highlights the need for further study into cardiovascular risks in this largely overlooked group.
A new study found that testing blood pressure load, which detects elevated readings over 24 hours, is not necessary for diagnosing hypertension in children. Having high average blood pressure on a 24-hour test does strongly predict risk of cardiac and kidney disease.
A study published in JAMA Cardiology found that individuals who maintain intermediate to ideal cardiovascular health for longer periods are 33% less likely to develop hypertension and other diseases. This suggests that promoting healthy behaviors throughout life may be beneficial for reducing the risk of chronic diseases and mortality.
Obesity increases levels of peroxynitrite-making enzymes in tiny cell membranes, silencing TRPV4 and lowering calcium entry. This leads to increased blood pressure. Targeting peroxynitrite or enzymes that make it may be an effective way to treat high blood pressure in obesity.
A large-scale analysis of electronic health record data found that 60% of patients had controlled blood pressure, but only 12% received new medication when readings were high. Improving medication intensification rates could lead to significant improvements in blood pressure control.
Researchers studied 82,000 non-Hispanic blacks and 370,000 whites finding significant differences in heart disease risk factors among black ethnic groups. African immigrants had lower prevalence of high blood pressure, smoking, diabetes, and obesity compared to Afro-Caribbeans and African Americans.
A randomized clinical trial in 60 urban workplaces in China found that a wellness program with hypertension management component significantly improved blood pressure control among employees. The program reduced systolic blood pressure by 3.5 mmHg and diastolic blood pressure by 2.5 mmHg compared to usual care.
A new study found that high blood pressure in young adulthood is associated with significant declines in cognitive function and gait in midlife. The research, published in Circulation, suggests that treating high blood pressure earlier may prevent future cognitive decline and mobility issues.
Studies have shown that chronic kidney disease (CKD) patients are more susceptible to salt-induced hypertension. A recent study published in Kidney International found a link between the immune system and salt sensitivity in CKD, with TNF-α triggering high blood pressure.
A study found that combining home blood pressure telemonitoring with phone-based lifestyle counseling significantly lowered systolic blood pressure in minority stroke survivors. After 12 months, those who received both interventions experienced a 14-point reduction, compared to 5 points for those with only telemonitoring.
A multi-country intervention trial found that community health worker-led care led to significant reductions in blood pressure and improved hypertension management. The study, conducted in Bangladesh, Pakistan, and Sri Lanka, showed a 5mmHg decline in systolic blood pressure and better BP control in the intervention group.
Researchers found that morning versus evening dosing of warfarin has insignificant effect on anticoagulant stability, suggesting patients can take medication at any regular time. A separate study showed that home blood pressure monitoring in cases of clinical uncertainty can improve hypertension control and patient understanding.
A new study found that two-thirds of patients with unchanged hypertension treatment had normal blood pressure readings at home, highlighting the effectiveness of therapeutic inertia. The study suggests that accepting home blood pressure metrics can improve healthcare quality metrics and patient education.
A new study has found that the guideline-recommended diuretic chlorthalidone causes more serious side effects, including hypokalemia and kidney problems, compared to hydrochlorothiazide. The study analyzed data from over 730,000 individuals treated for hypertension.
Researchers have found that natural antioxidant L-ergothioneine can relieve some clinical symptoms of Pre-eclampsia in rats, including reduced blood pressure and fetal growth restriction. Further study is needed to validate its safety and efficacy in humans.
Scientists have created a protein drug composed of angiotensin converting enzyme-2 (ACE2) and its product angiotensin (1-7) that can be taken orally to treat pulmonary arterial hypertension. The drug has shown promise in animal models, reducing pulmonary artery pressure and improving cardiac function.
Researchers find that free radicals produced by immune cells in the kidneys contribute to salt-sensitive hypertension. By targeting these ROS-producing immune cells, effective therapies may be developed to alleviate blood pressure and kidney damage.
A new study by researchers at the University of Washington found that increases in minimum wages had no overall effect on the health of working-age people. However, they did find a mix of negative and positive effects associated with the health of certain subgroups, including increased obesity rates among working-age people of color.
A study found nearly 4 out of 10 women readmitted for high blood pressure had no prior history. All women should be educated on postpartum hypertension before discharge.
Research from Martin-Luther-University Halle-Wittenberg found that integrating high-intensity interval training (HIIT) into standard physical education improved children's health within a short period of time. HIIT alternates intense exercise with recovery periods, effectively motivating children to exercise.
A new study explores the connection between early high blood pressure and increased risk of dementia. Researchers are using advanced brain imaging techniques to examine cerebral blood flow, cognitive function, and brain structure in midlife individuals with elevated blood pressure.
Research led by Duke Health finds wide swings in young adult blood pressure readings increase cardiovascular disease risk by middle age. The study suggests ignoring variability in blood pressure readings may mask an early warning sign of heart disease.
A new study published in Hypertension found that reducing sodium intake decreases thirst and urine volume, but does not affect metabolic energy needs. This results support the traditional notion that decreasing sodium intake is critical to managing hypertension.
A new study found that quercetin can greatly reduce systolic blood pressure and improve HDL cholesterol levels. Quercetin administration is associated with a 10-20% reduction in cardiovascular risk for heart failure, stroke, and myocardial infarction.
A new study from the Smidt Heart Institute found that women's blood vessels age faster and are more susceptible to high blood pressure earlier in life. The research highlights sex differences in cardiovascular physiology and disease, emphasizing the need for tailored treatment approaches.
Researchers at University College London discovered a new mechanism that allows the brain to monitor its own blood supply, potentially leading to new treatments for hypertension and dementia. Astrocytes, specialized brain cells, act as blood flow sensors to regulate brain blood flow and maintain oxygen supply.
A new study published in Blood Advances reveals that patients with metabolic syndrome are more likely to experience recurrent blood clots. The study analyzed 151,054 patients diagnosed with deep vein thrombosis and found that those with comorbid metabolic syndrome conditions had a higher risk of VTE recurrence.
Half of women with heart failure do not receive adequate treatment due to the underlying cause being unrelated to a heart attack, leading to progressive stiffening of the heart. Obesity and high blood pressure are significant risk factors for this type of heart failure in women.
A new study by a Canadian research team found that office workers who spend long hours on the job are more likely to have high blood pressure, including masked hypertension. The study of over 3,500 white-collar employees revealed a link between long working hours and sustained hypertension.
Traffic-related air pollution has been linked to an increased risk of hypertensive disorders in pregnant women, with exposure to particulate matter (PM2.5) associated with a 50% higher likelihood of developing preeclampsia. The study highlights the need for further research into the impact of environmental exposures during pregnancy.
A study found that cell secretions may be the cause of elevated nighttime blood pressure in patients with apnea, leading to cardiovascular complications. The researchers identified a potential diagnostic test using blood exosomes to assess cardiovascular risk.
A new study published in PLOS One suggests that mindfulness training can significantly reduce blood pressure readings and improve self-regulation skills. The nine-week customized Mindfulness-Based Blood Pressure Reduction program was developed for participants with elevated blood pressure and showed positive effects, particularly for t...
A four-year study found that immigration deportation worries double the risk of developing high blood pressure in Mexican-born women, highlighting potential negative impacts on cardiovascular health. The study suggests considering immigration policies' effects on stress levels and subsequent blood pressure outcomes.
Studies on mice suggest that a neuropeptide αCGRP has beneficial effects on the heart in patients with high blood pressure. Physical activity increases αCGRP levels, which help prevent pathological heart remodeling and cardiac dysfunction. However, long-term use of αCGRP blockers may be hazardous for these patients.
Recent studies found that smokers and hypertensive individuals have better chances to survive subarachnoid hemorrhage than non-smokers and those with normal blood pressures. However, a new Finnish study included patients who died before reaching hospital wards and showed the opposite - that these groups are more likely to die from brai...
The new 2019 Clinical Performance and Quality Measures for Adults with High Blood Pressure aim to accelerate translation of scientific evidence into clinical practice. The measures evaluate patient care in accordance with the 2017 Hypertension Clinical Practice Guidelines, including timeliness, safety, effectiveness, efficiency, equity...
Two studies examine the effects of intensive blood pressure control on life expectancy, with a target systolic blood pressure of less than 120 mm Hg. A cost-effectiveness analysis found that targeting high-risk patients is the most cost-effective approach over 10 years.
Research confirms women with gestational hypertension or preeclampsia have higher cardiovascular risk and persistent risks into their 60s. Women are advised to adopt heart-healthy modifications such as exercising, eating healthy and controlling weight.
Researchers found that activating the apelin receptor led to increased blood pressure due to vasoconstriction, a process also affected by the α1A-adrenergic receptor. The study suggests a coordinated mechanism controlling blood vessel contraction and may support therapy development for vascular stenosis and vasospasm.
A Yale-coauthored paper in Lancet analyzed data from 4.9 million patients to compare the safety and effectiveness of five classes of first-line hypertension medications. Thiazide or thiazide-like diuretics were found to be better at preventing heart attack, heart failure, and stroke than ACE inhibitors.
A recent study analyzing data from over 12,500 black adults in the US found that nearly 32.5% of cardiovascular disease cases are attributed to hypertension. Maintaining normal blood pressure may help reduce CVD among black adults, according to the research.
A Swedish study analyzed over 2.5 million births between 1973 and 1997 to examine the health outcomes of people born prematurely. The results show that 54.6% of those born preterm remained healthy without major conditions such as asthma, hypertension, or epilepsy by age 43, compared to 63% of full-term births.
A new study published in the European Heart Journal found that taking anti-hypertensive medication at bedtime reduces the risk of cardiovascular disease and death by nearly half compared to morning medication. Patients who took their medication at night had better-controlled blood pressure and a significantly lower risk of heart attack...
Researchers discovered a structural change in brain cells controlling salt-resistance, which can be mimicked to combat high blood pressure. This finding has implications for the development of targeted therapies for salt-resistant individuals.