Research on high blood pressure and its consequences. Covers heart-failure prediction, kidney-disease models, AI detection, and cardiovascular risk.
Researchers propose that elevated pulse pressure in blood traveling to the brain can cause inflammation, oxidative stress, and cellular dysfunction, leading to brain damage and cognitive decline. The study suggests reducing elevated pulse pressure could prove synergistic with other therapeutic approaches to treat dementia.
Researchers created transgenic rice with anti-hypertensive peptides that lowered blood pressure in hypertensive rats. The effect remained after a 5-week treatment period without obvious side effects. If effective in humans, it could lead to a daily intake of only half a tablespoon of special rice.
Researchers found that females upregulate anti-inflammatory T cells to maintain lower blood pressures, which may lead to new hypertension treatment strategies for females. In contrast, males did not show a significant response to reduced Treg levels, suggesting their blood pressure is less dependent on this mechanism.
Researchers investigate medication use in older adults, finding that certain hypertension medications may reduce dementia risk and improve stroke outcomes. A deprescribing program also shows promise in reducing falls risk, with primary care providers accepting over 90% of recommendations.
A high-salt diet has been found to have a significant impact on the health of the gut microbiome and blood pressure in adults with untreated hypertension. In a six-week study, participants who reduced their sodium intake experienced increased levels of short-chain fatty acids and lower blood pressure.
A new analysis of the Framingham Heart Study found that brain bleeds called intracerebral hemorrhages remained stable in incidence among all age groups over the past 30 years. However, they increased in people 75 and older, with a threefold increase in seniors taking anticoagulants. The study suggests that thinners could be a factor, b...
Research published in the European Heart Journal found that patients with high blood pressure are at a two-fold increased risk of dying from COVID-19 compared to those without hypertension. The study also suggests that RAAS inhibitors may be protective against COVID-19-related death.
A single negative high-quality screening colonoscopy was associated with reduced colorectal cancer incidence and mortality. The study found a 90% reduction in CRC mortality over 17.4 years, suggesting that the current 10-year screening interval could safely be extended.
Over half of mums-to-be at risk of pre-eclampsia are not receiving preventive aspirin treatment, says consultant obstetrician. Making aspirin available from local pharmacies could help ward off the condition, says Dr Joanna Girling.
High blood pressure during and after exercise is associated with a higher risk of hypertension, preclinical cardiovascular disease, and death in middle-aged to older adults. Regular physical activity and monitoring blood pressure numbers can help lower this risk.
A large international study found that consuming at least two daily servings of dairy products is associated with lower risks of diabetes and high blood pressure. Full-fat dairy products showed the strongest associations, particularly in countries with low dairy intakes.
A bitter melon extract intervention restored TRPM5-mediated aversion to high salt stimuli, reducing excessive salt intake and improving cardiovascular damage in mice. This approach may provide a promising strategy for reducing high salt-induced hypertension and cardiac hypertrophy.
Researchers investigated associations between 26 common medical conditions and alcohol use among 2.7 million patients. The study found significant links between certain health issues, such as diabetes and high blood pressure, and excessive drinking.
A new study published in the Canadian Journal of Cardiology suggests that women's treatment decisions during pregnancy should be tailored to their individual values and preferences. The research found that half of the women preferred tight control of blood pressure, while half preferred less-tight control, with Caucasian ethnicity, uni...
The International Society of Hypertension has released the first global practice guidelines for managing hypertension, developed by a world-wide panel of experts. The guidelines aim to simplify treatment approaches in resource-poor settings, addressing the challenge of accessing cutting-edge medical equipment and technology.
Researchers evaluated teens with normal weight and those with obesity, type 2 diabetes or high blood pressure to assess carotid artery health. Teens with these conditions were found to have thicker and stiffer arteries, increasing the risk of early heart attacks and strokes.
A recent study found that women who experienced hypertensive disorders during pregnancy are at a higher risk of developing heart or kidney diseases earlier in life. The study, which analyzed data from over 7,500 women, suggests that this risk may be underestimated when considering only per-pregnancy rates.
A study published in the American Heart Association journal Hypertension found that intensive blood pressure control reduces the risk of atrial fibrillation. Lowering systolic blood pressure to less than 120mmHg resulted in a 26% lower risk of AFib compared to standard lowering, with similar benefits seen across different groups.
New research reveals that exposure to loud noise can lead to high blood pressure and potentially cancer-related DNA damage in mice. Healthy mice exposed to aircraft noise were more likely to develop high blood pressure.
A novel protein, thrombospondin-1 (Thbs1), plays a crucial role in mechanotransduction in blood vessel walls, enabling cells to adapt to changing mechanical forces. The absence of Thbs1 can lead to weakened blood vessel walls, increasing the risk of cardiovascular disease.
Research team finds that high-altitude adaptations in the Himalayas may lower risk for hypertension and diabetes-associated anemia. The study, led by Katherine Wander of Binghamton University, found that a Tibetan-descended population living in Southwest China had lower rates of these conditions compared to low-altitude Han populations.
A study examined the association between renin-angiotensin system inhibitors and COVID-19 severity, finding no significant link to increased risk of death or severe illness. However, some studies suggest that these medications may exacerbate respiratory symptoms in patients with underlying hypertension.
A Finnish study found associations between hypertensive pregnancy disorders, including preeclampsia, and childhood mental disorders. Maternal preeclampsia was associated with a 66% higher risk of mental disorders in offspring, while severe preeclampsia increased the risk by two-fold.
A new study shows that people with high blood pressure and reverse dipping may have small areas in the brain damaged from vascular disease, leading to memory problems. Those with high blood pressure and reverse dipping also had lower scores on a memory test, with average scores of about 33 compared to 40 for those without these conditi...
A Canadian study found that nearly a quarter of adults suffer from hypertension, with a notable decline in awareness, treatment, and control rates, particularly among women. The findings highlight the need for urgent re-engagement on blood pressure treatment and control to combat preventable deaths and disability.
A larger thigh circumference may be associated with lower blood pressure and a reduced risk of heart disease in people with obesity. Thigh circumference could potentially be used as an indicator for earlier detection and prevention of high blood pressure and related complications.
A new study published by Oxford University Press USA found that mat Pilates training significantly reduces arterial stiffness and blood pressure in young obese women with elevated blood pressure. The study, which included 12 weeks of mat Pilates training, also found a decrease in body fatness.
A new study published in the Journal of the Endocrine Society found that chemicals such as bisphenol A (BPA) substitutes can affect fetal development and lead to hypertension in later life. The research, conducted on pregnant rats, suggests that even low-dose exposure to these chemicals can impact blood pressure later in life.
Recent research suggests that ACE inhibitors and angiotensin receptor blockers can have a beneficial effect on COVID-19 outcomes for hypertensive patients. A review of over 60 published studies found no evidence to support concerns about these drugs increasing the risk of infection or disease severity.
Patients with untreated high blood pressure experienced statistically significant reductions in average blood pressure over 24 hours following renal denervation. The procedure offered an effective alternative approach to traditional medications, lowering blood pressure throughout the day and early morning periods.
A study published in the American Heart Association journal Hypertension finds no credible evidence that ARBs increase COVID-19 susceptibility. Discontinuing these medications would pose significant health risks for patients with hypertension and chronic kidney disease.
A new study found that cumulative doses of oral steroids are associated with increased hypertension, affecting over 24,000 adults with chronic inflammatory diseases. The researchers recommend closer monitoring of blood pressure in these patients.
Research shows female mice accumulate more liver fat than males but are better at using it up, potentially benefiting women's health. Fasting may be beneficial for women specifically due to its impact on liver health.
Rates of deaths related to hypertension have risen sharply across the US, with a 72% increase in rural areas and a 20% increase in urban areas. High blood pressure can cause damage to arteries and lead to events such as heart attacks or strokes, emphasizing the importance of taking it seriously.
A study of 329 female college athletes found nearly half had higher than normal blood pressure levels, with 61% classified as elevated. The research highlights the need for further study into cardiovascular risks in this largely overlooked group.
A new study found that testing blood pressure load, which detects elevated readings over 24 hours, is not necessary for diagnosing hypertension in children. Having high average blood pressure on a 24-hour test does strongly predict risk of cardiac and kidney disease.
A study published in JAMA Cardiology found that individuals who maintain intermediate to ideal cardiovascular health for longer periods are 33% less likely to develop hypertension and other diseases. This suggests that promoting healthy behaviors throughout life may be beneficial for reducing the risk of chronic diseases and mortality.
Obesity increases levels of peroxynitrite-making enzymes in tiny cell membranes, silencing TRPV4 and lowering calcium entry. This leads to increased blood pressure. Targeting peroxynitrite or enzymes that make it may be an effective way to treat high blood pressure in obesity.
A large-scale analysis of electronic health record data found that 60% of patients had controlled blood pressure, but only 12% received new medication when readings were high. Improving medication intensification rates could lead to significant improvements in blood pressure control.
Researchers studied 82,000 non-Hispanic blacks and 370,000 whites finding significant differences in heart disease risk factors among black ethnic groups. African immigrants had lower prevalence of high blood pressure, smoking, diabetes, and obesity compared to Afro-Caribbeans and African Americans.
A randomized clinical trial in 60 urban workplaces in China found that a wellness program with hypertension management component significantly improved blood pressure control among employees. The program reduced systolic blood pressure by 3.5 mmHg and diastolic blood pressure by 2.5 mmHg compared to usual care.
A new study found that high blood pressure in young adulthood is associated with significant declines in cognitive function and gait in midlife. The research, published in Circulation, suggests that treating high blood pressure earlier may prevent future cognitive decline and mobility issues.
Studies have shown that chronic kidney disease (CKD) patients are more susceptible to salt-induced hypertension. A recent study published in Kidney International found a link between the immune system and salt sensitivity in CKD, with TNF-α triggering high blood pressure.
A study found that combining home blood pressure telemonitoring with phone-based lifestyle counseling significantly lowered systolic blood pressure in minority stroke survivors. After 12 months, those who received both interventions experienced a 14-point reduction, compared to 5 points for those with only telemonitoring.
A multi-country intervention trial found that community health worker-led care led to significant reductions in blood pressure and improved hypertension management. The study, conducted in Bangladesh, Pakistan, and Sri Lanka, showed a 5mmHg decline in systolic blood pressure and better BP control in the intervention group.
A new study found that two-thirds of patients with unchanged hypertension treatment had normal blood pressure readings at home, highlighting the effectiveness of therapeutic inertia. The study suggests that accepting home blood pressure metrics can improve healthcare quality metrics and patient education.
Researchers found that morning versus evening dosing of warfarin has insignificant effect on anticoagulant stability, suggesting patients can take medication at any regular time. A separate study showed that home blood pressure monitoring in cases of clinical uncertainty can improve hypertension control and patient understanding.
A new study has found that the guideline-recommended diuretic chlorthalidone causes more serious side effects, including hypokalemia and kidney problems, compared to hydrochlorothiazide. The study analyzed data from over 730,000 individuals treated for hypertension.
Researchers have found that natural antioxidant L-ergothioneine can relieve some clinical symptoms of Pre-eclampsia in rats, including reduced blood pressure and fetal growth restriction. Further study is needed to validate its safety and efficacy in humans.
Scientists have created a protein drug composed of angiotensin converting enzyme-2 (ACE2) and its product angiotensin (1-7) that can be taken orally to treat pulmonary arterial hypertension. The drug has shown promise in animal models, reducing pulmonary artery pressure and improving cardiac function.
Researchers find that free radicals produced by immune cells in the kidneys contribute to salt-sensitive hypertension. By targeting these ROS-producing immune cells, effective therapies may be developed to alleviate blood pressure and kidney damage.
A new study by researchers at the University of Washington found that increases in minimum wages had no overall effect on the health of working-age people. However, they did find a mix of negative and positive effects associated with the health of certain subgroups, including increased obesity rates among working-age people of color.
A study found nearly 4 out of 10 women readmitted for high blood pressure had no prior history. All women should be educated on postpartum hypertension before discharge.
Research from Martin-Luther-University Halle-Wittenberg found that integrating high-intensity interval training (HIIT) into standard physical education improved children's health within a short period of time. HIIT alternates intense exercise with recovery periods, effectively motivating children to exercise.
A new study explores the connection between early high blood pressure and increased risk of dementia. Researchers are using advanced brain imaging techniques to examine cerebral blood flow, cognitive function, and brain structure in midlife individuals with elevated blood pressure.
Research led by Duke Health finds wide swings in young adult blood pressure readings increase cardiovascular disease risk by middle age. The study suggests ignoring variability in blood pressure readings may mask an early warning sign of heart disease.
A new study published in Hypertension found that reducing sodium intake decreases thirst and urine volume, but does not affect metabolic energy needs. This results support the traditional notion that decreasing sodium intake is critical to managing hypertension.
A new study from the Smidt Heart Institute found that women's blood vessels age faster and are more susceptible to high blood pressure earlier in life. The research highlights sex differences in cardiovascular physiology and disease, emphasizing the need for tailored treatment approaches.
A new study found that quercetin can greatly reduce systolic blood pressure and improve HDL cholesterol levels. Quercetin administration is associated with a 10-20% reduction in cardiovascular risk for heart failure, stroke, and myocardial infarction.
Researchers at University College London discovered a new mechanism that allows the brain to monitor its own blood supply, potentially leading to new treatments for hypertension and dementia. Astrocytes, specialized brain cells, act as blood flow sensors to regulate brain blood flow and maintain oxygen supply.