A University of Colorado Cancer Center study found that SPARC acts as an anti-inflammatory drug, reducing tumor growth and metastasis in bladder cancer. The protein is produced by healthy tissue to mute tumors, but aggressive cancers suppress its production, leading to faster disease progression.
SourceUniversity of Colorado Anschutz Medical Campus·JournalJournal of Clinical Investigation·DateJan 16, 2013
Researchers at Fox Chase Cancer Center found that the NEDD9 gene controls the growth of progenitor cells that give rise to tumors, suggesting a new approach to treating breast cancer. The study also identified a link between NEDD9 levels and sensitivity to certain drugs.
SourceFox Chase Cancer Center·JournalOncogene·DateJan 14, 2013
A Weill Cornell study reveals that a specific miRNA, miR-708, acts as a metastatic tumor inhibitor and can be restored to stop the spread of aggressive breast cancer. Synthetic miR-708 delivery has blocked metastatic outgrowth in mice, making it a promising therapeutic target.
SourceWeill Cornell Medicine·JournalCancer Cell·DateJan 14, 2013
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Dr. Nicholas Navin's new approach to genetic analysis could help researchers understand and map the complex process of cancer evolution, ultimately blocking the spread of cancer to other organs. The project aims to identify important mutations in single tumor cells at various stages of cancer development.
SourceUniversity of Texas M. D. Anderson Cancer Center·DateJan 10, 2013
A study of 722 patients found that those taking beta-blockers for other conditions lived longer after receiving radiotherapy. The use of beta-blockers improved survival rates without disease spreading or recurring, but not locoregional progression-free survival.
SourceEuropean Society for Medical Oncology·JournalAnnals of Oncology·DateJan 8, 2013
The Damon Runyon-Rachleff Innovation Award funds cancer research by exceptionally creative thinkers with 'high-risk/high-reward' ideas, selected through a rigorous process. Seven awardees aim to develop new approaches to fighting cancer, including virus-based treatments and single-cell sequencing tools.
SourceDamon Runyon Cancer Research Foundation·DateJan 7, 2013
Researchers at Virginia Commonwealth University discovered that gene mda-9/syntenin regulates angiogenesis, a process responsible for forming new blood vessels in tumors. IGFBP-2, found to be elevated in most cancers, may serve as a novel biomarker for disease progression.
SourceVirginia Commonwealth University·JournalCancer Research·DateJan 3, 2013
Thomas Jefferson University researchers have identified new pathways that drive aggressive forms of prostate cancer. Elevated levels of Cyclin D1b function as a novel biomarker for lethal metastatic disease in prostate cancer patients.
SourceThomas Jefferson University·JournalJournal of Clinical Investigation·DateDec 21, 2012
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers identified ID proteins as regulators of glioma progression and potential therapeutic targets. In contrast, the loss of TREM-1 increased inflammation and worsened lung infection outcomes in mice. Additionally, breast cancer cells interact with stroma to drive metastasis through HIF-dependent signaling pathways.
SourceJCI Journals·JournalJournal of Clinical Investigation·DateDec 17, 2012
Researchers have discovered a new therapy combination that targets the PI3K and JAK2/STAT5 pathways to combat aggressive metastatic breast cancer. In mouse studies, this approach led to slower tumor growth, reduced spread, and improved survival rates.
A study by Dr. George M Yousef at St. Michael's Hospital identified 29 proteins associated with kidney tumor metastasis. These biomarkers can help physicians recognize which tumors are more likely to spread, enabling targeted treatment and improved patient outcomes.
SourceSt. Michael's Hospital·JournalMolecular & Cellular Proteomics·DateDec 5, 2012
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers at University of California, San Diego School of Medicine discovered the reversible EMT switch in metastasis, resolving a decade-long debate. Activation of Twist1 gene promotes carcinoma cells to disseminate into blood circulation, while turning off EMT switch is crucial for proliferation and formation of secondary tumors.
SourceUniversity of California - San Diego·JournalCancer Cell·DateNov 29, 2012
A cost-effectiveness analysis found that KRAS testing is cost-saving, while BRAF testing offers additional savings. The study suggests that molecular testing primarily generates cost savings by identifying nonresponders, rather than improving survival.
SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateNov 28, 2012
Researchers identified a group of microRNAs that work together to suppress the spread of cancer by repressing epithelial-to-mesenchymal transition. This discovery offers potential therapeutic targets and diagnostic tools for predicting and inhibiting cancer metastasis.
SourceScripps Research Institute·JournalJournal of Biological Chemistry·DateNov 28, 2012
Researchers found that high levels of COUP-TFII can overcome a natural barrier to prostate cancer progression, allowing tumor cells to grow and spread throughout the body. The study suggests that COUP-TFII is an important 'second hit' for the progression of prostate cancer and metastasis.
SourceBaylor College of Medicine·JournalNature·DateNov 28, 2012
Dr. Debra Auguste aims to develop targeted treatments for four metastatic breast cancer populations using engineered liposomes that deliver short interfering RNA to inhibit tumor progression and metastasis. The goal is to enhance cooperative binding, reduce cell migration, and improve treatment efficacy.
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers at the University of Copenhagen have discovered that a protein known for causing cancer cells to spread is also involved in brain repair. The study, published in Nature Communications, suggests new avenues for treating degenerative brain diseases like Alzheimer's.
SourceUniversity of Copenhagen·JournalNature Communications·DateNov 16, 2012
A study published in the Journal of Thoracic Oncology found that denosumab was associated with significantly improved overall median survival in lung cancer patients, including those with non-small-cell lung cancer and small-cell lung cancer. The treatment also showed improved survival in patients with squamous cell carcinoma.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateNov 15, 2012
Scientists at Virginia Commonwealth University have made a significant breakthrough in understanding how cancer spreads, discovering that a specific protein can be inhibited to stop melanoma metastasis. The research could lead to new targeted therapies and diagnostic tools for patients with melanoma and potentially other cancers.
SourceVirginia Commonwealth University·JournalCancer Research·DateNov 14, 2012
A new gene delivery vehicle has been developed to target tumor cells with the TNFα cytokine, allowing for improved drug delivery and reduced resistance. The treatment approach combines the cytokine with a DNA-intercalating drug doxorubicin, showing promise in reducing tumor growth and metastasis.
SourceLudwig-Maximilians-Universität München·JournalMolecular Therapy·DateNov 14, 2012
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
A team of researchers found that tumour cells form alliances with surrounding healthy cells, called stroma, to colonize other organs during metastasis. This discovery could lead to a test to predict relapse and tailored treatment regimes for patients.
SourceInstitute for Research in Biomedicine (IRB Barcelona)·JournalCancer Cell·DateNov 12, 2012
A combination of an anti-HER2 drug and an angiogenesis inhibitor significantly improves survival in a mouse model of brain metastatic breast cancer. The treatment extends patient survival by slowing the growth of brain tumors, making it a promising approach for patients with HER2-positive breast cancer who develop brain metastases.
SourceMassachusetts General Hospital·JournalProceedings of the National Academy of Sciences·DateNov 1, 2012
Researchers developed a diagnostic tool identifying breast cancer cells' ability to spread, based on their lipid profile. The technique, Raman microspectroscopy, has shown promise for routine cytological diagnosis and may be extended to other tumors.
SourceIDIBELL-Bellvitge Biomedical Research Institute·JournalPLOS ONE·DateOct 18, 2012
Researchers found that genetic imbalances in most cases determine the evolution from noninvasive to invasive disease. The study identified patterns consistent with known aberration profiles for breast cancer, including the loss of tumor suppressor CDH1 and gain of oncogene MYC.
SourceElsevier Health Sciences·JournalAmerican Journal Of Pathology·DateOct 16, 2012
Breast tumor cells interact with mesenchymal stem cells (MSCs) in the tumor microenvironment, triggering production of lysyl oxidase (LOX), a gene that enables cell migration and metastasis. This process, called epithelial-to-mesenchymal transition (EMT), allows cancer cells to spread to bones and other parts of the body.
SourceBeth Israel Deaconess Medical Center·JournalProceedings of the National Academy of Sciences·DateOct 11, 2012
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
A new MIT study reveals cellular adhesion molecules critical to cancer's metastasis, offering potential new targets for cancer drug therapy. The researchers found that adhesion tendencies of metastatic cells from different primary tumors were similar, suggesting a shared pathway.
SourceMassachusetts Institute of Technology·JournalNature Communications·DateOct 9, 2012
Research reveals that Col6 protein's endotrophin alter tumor environment promoting growth and metastasis in mice. Reduced endotrophin expression linked to lower tumor burden and fewer metastases.
SourceJCI Journals·JournalJournal of Clinical Investigation·DateOct 8, 2012
A large-scale trial has successfully tested whole-genome cancer testing to identify targeted therapies for patients with metastatic breast cancer. The study found that around 20% of patients had rare and unexpected genomic alterations, highlighting the need for whole-genome approaches.
SourceEuropean Society for Medical Oncology·JournalAnnals of Oncology·DateOct 1, 2012
A team of researchers from MD Anderson Cancer Center has identified the LIFR protein as a novel suppressor of breast cancer metastasis. The study found that restoring LIFR expression or function could be used to block the spread of breast cancer. Loss of LIFR is associated with poor clinical outcomes in breast cancer patients.
SourceUniversity of Texas M. D. Anderson Cancer Center·JournalNature Medicine·DateSep 24, 2012
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Researchers developed a new nanotechnology that detects micrometastases in mouse models of breast cancer, marking them for early diagnosis and treatment. The technology uses nanochains to target cancer cells with integrins, allowing doctors to guide surgery or deliver cancer-killing drugs directly to the cells before a tumor forms.
SourceCase Western Reserve University·JournalACS Nano·DateSep 24, 2012
Researchers have discovered that melanoma cells produce receptors for chemokines present in the brain tissue, drawing them to the brain. This interaction could be a potential target for new therapies.
SourceAmerican Friends of Tel Aviv University·JournalInternational Journal of Cancer·DateSep 19, 2012
Researchers at Thomas Jefferson University found that decorin, a naturally occurring substance, induces tumor suppressor genes in the surrounding tissue of triple negative breast cancer tumors. This breakthrough may lead to improved therapeutics for metastatic breast cancer.
SourceThomas Jefferson University·JournalPLOS ONE·DateSep 19, 2012
Chemists at UMass Amherst have developed a sensor array system using gold nanoparticles and proteins that can rapidly detect and identify different cancer types in living tissue. The technology uses a 'nose' strategy similar to how humans recognize odors, allowing for precise detection of metastatic cells with high accuracy.
SourceUniversity of Massachusetts Amherst·JournalACS Nano·DateSep 13, 2012
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
Research reveals that tumor hypoxia drives aggressive behavior and poorer prognosis in various cancers. CD24 overexpression is linked to tumor growth and metastasis, making it a potential therapeutic target.
SourceUniversity of Colorado Anschutz Medical Campus·JournalCancer Research·DateSep 13, 2012
A new CT linked technique improved the detection of positive sentinel lymph nodes and increased disease-free survival rates among melanoma patients. The study found that patients who underwent preoperative SPECT/CT imaging had a higher rate of metastatic node detection and longer disease-free survival.
Breast cancer cells spread to surrounding lymph nodes through invasion into lymph vessels. Johns Hopkins researchers discover protein HIF-1 triggers this process by stimulating the growth of new blood vessels and activating genes involved in lymph vessel formation.
SourceJohns Hopkins Medicine·JournalProceedings of the National Academy of Sciences·DateSep 10, 2012
A study of 340 stage III NSCLC patients found that prophylactic cranial irradiation (PCI) significantly reduces the risk of brain metastases, but no improvement in overall survival was observed. The rate of brain metastases for PCI-treated patients was 17.3%, compared to 26.8% for observational arm.
SourceAmerican Society for Radiation Oncology·JournalJournal of Thoracic Oncology·DateSep 6, 2012
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Researchers found that high F-18-FDG uptake in axillary lymph nodes before treatment can predict disease-free survival in invasive ductal breast cancer patients. A nodal SUVmax of 2.8 was identified as the optimal cutoff for predicting disease-free survival.
SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateSep 4, 2012
A WSU researcher has identified over 40 plant-based compounds that can turn on genes that slow the spread of cancer. The study highlights the potential role of diet and nutrition in controlling cancer's spread.
SourceWashington State University·JournalCancer and Metastasis Reviews·DateAug 27, 2012
Researchers used Active Shape Model to simulate fluid forces acting on breast cancer cells in blood flow. The study aims to develop new therapies targeting metastasis by understanding mechanical properties of cancer cells.
SourceAmerican Institute of Physics·JournalPhysics of Fluids·DateAug 24, 2012
A study published in the Journal of the National Cancer Institute found that LPA1 inhibition induces metastatic dormancy in mouse models of breast cancer. The inhibitor, Debio-0719, suppresses metastases without affecting primary tumor size.
SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateAug 21, 2012
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Researchers have identified sphingosine kinase as a key player in promoting resistance to breast cancer therapies, such as tamoxifen. Targeted inhibition of SK has shown potential in inducing cell death and blocking tumor growth in drug-resistant models.
SourceSociety for Experimental Biology and Medicine·JournalExperimental Biology and Medicine·DateAug 9, 2012
Research finds that TRPM7 protein plays a critical role in breast cancer cell metastasis. High levels of TRPM7 expression are associated with poor patient outcomes and increased risk of distant metastases. The study suggests that targeting this protein could block metastasis, offering new therapeutic opportunities.
SourceAmerican Association for Cancer Research·JournalCancer Research·DateAug 7, 2012
A study by Lawson Research Institute suggests that breast cancer stem cells have a preference for specific organs, such as the lung and brain, when spreading to other sites. Researchers hope to uncover the underlying factors driving this phenomenon and potentially develop new strategies to target these aggressive cells.
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
Researchers found that CCR9 is abundant in early stage colon cancer but lacks in invasive and metastatic cancer, suggesting its role in reducing cancer spread. Activation of NOTCH promotes degradation of CCR9, inhibiting the chemokine-induced signaling pathway.
SourceJCI Journals·JournalJournal of Clinical Investigation·DateAug 6, 2012
Researchers at Michigan State University have identified a key protein called MLK3 that drives breast cancer cell migration and invasion. By targeting this protein, they hope to develop new therapies to prevent the spread of cancer.
SourceMichigan State University·JournalCancer Research·DateAug 1, 2012
Researchers discover antibodies to malaria surface protein PfEMP1 mediate human immunity; CCL25 pathway suppresses colon cancer metastasis; and a retargeted botulinum toxin inhibits hormone production in acromegaly.
SourceJCI Journals·JournalJournal of Clinical Investigation·DateAug 1, 2012
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
The study found that without PSA testing, approximately 25,000 cases of advanced prostate cancer would occur in 2008, three times the actual number observed. This would result in more men experiencing aggressive disease with limited treatment options.
The study suggests that eliminating the PSA test would result in more men being diagnosed with metastatic prostate cancer, leading to higher mortality rates. Prostate cancer death rates have been reduced by nearly 40% over the past 20 years, largely due to early detection through PSA testing.
SourceUniversity of Rochester Medical Center·JournalCancer·DateJul 30, 2012
A recent study published in Cancer Biotherapy and Radiopharmaceuticals suggests that high-dose interleukin-2 (IL-2) should continue to be the initial treatment for patients with stage IV metastatic melanoma. The researchers recommend intensive IL-2 therapy as a viable option, either alone or in combination with newer therapeutic agents.
SourceMary Ann Liebert, Inc./Genetic Engineering News·JournalCancer Biotherapy and Radiopharmaceuticals·DateJul 26, 2012
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Researchers have identified RhoC as a key driver of breast cancer stem cell metastasis. High levels of RhoC are associated with worse patient survival rates. Targeting this molecule may lead to more effective treatments for certain types of cancer, potentially managing cancer stem cells and invasive behaviors.
SourceMichigan Medicine - University of Michigan·JournalPLOS ONE·DateJul 24, 2012
Researchers at Vanderbilt University Medical Center found that stress activates the sympathetic nervous system, which promotes breast cancer cell colonization of bone. Beta-blockers, such as propranolol, can prevent this process by inhibiting sympathetic nervous system signals.
SourceVanderbilt University Medical Center·JournalPLOS Biology·DateJul 17, 2012
Physiologists and neuropathologists from the University of Zurich have identified the origin of metastasis formation in intestinal cancer cells. Cancer cells manipulate specific doorman receptors on blood vessel endothelium to enter other organs via bloodstream.
SourceUniversity of Zurich·JournalCancer Cell·DateJul 11, 2012
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
Researchers discovered that tumor cells release chemokine CCL2, which docks onto endothelial cells and activates the CCR2 receptor, making them permeable. This pathway enables tumor cells to migrate and metastasize.
SourceTechnical University of Munich (TUM)·JournalCancer Cell·DateJul 10, 2012
Researchers create high-throughput flow-through optical microscope to classify rare breast cancer cells in blood samples, boasting a throughput of 100,000 cells per second. The technology demonstrates real-time identification of rare cancer cells with a record low false-positive rate.
SourceUniversity of California - Los Angeles·JournalProceedings of the National Academy of Sciences·DateJul 5, 2012
A study published in Journal of Biological Chemistry found that prostate cancer cells lacking the protein SPDEF are unable to establish colonies at possible sites of metastasis, highlighting a potential biomarker for untreated cancers. Researchers hope to regulate SPDEF expression to prevent cancer cell metastasis.
SourceUniversity of Colorado Anschutz Medical Campus·JournalJournal of Biological Chemistry·DateJul 5, 2012
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Researchers analyzed genes expressed in circulating tumor cells and found increased expression of WNT2, a known oncogene, in CTCs from mouse models and human patients. Targeting the WNT2 pathway may reduce metastatic potential, which is critical for controlling pancreatic cancer.
SourceMassachusetts General Hospital·JournalNature·DateJul 1, 2012
Researchers discovered that NOG enables breast cancer cells to invade bone and establish tumors by increasing osteoclast activity and keeping cells in a stem-cell-like state. This gene plays a key role in the complex process of metastasis, increasing breast cancer's potential for spreading to the bone environment.
SourceAmerican Society for Biochemistry and Molecular Biology·JournalJournal of Biological Chemistry·DateJun 14, 2012
Research at Thomas Jefferson University discovered that senescent cells in the tumor microenvironment produce nutrients for cancer cells via autophagy, supporting their growth. This finding suggests that aging is a key factor in driving tumor growth and metastasis.
SourceThomas Jefferson University·JournalCell Cycle·DateJun 14, 2012
A new line of radioisotope therapy, Radium-223 chloride, has been shown to extend the lives of prostate cancer patients with advanced tumors that have spread to bone. The treatment has a short range of penetration and is usually well-tolerated, with serious side effects being rare.
SourceSociety of Nuclear Medicine and Molecular Imaging·DateJun 11, 2012