Research on pain and how to relieve it. Covers chemotherapy nerve injury, music and pain, migraine patterns, and back-pain treatments.
Older adults at risk of delirium following surgery due to preoperative pain and depressive symptoms. The study found a significant interaction between pain and depressive symptoms, increasing delirium risk by two-fold.
Research from scientists at Washington University School of Medicine found that scratching causes the brain to release serotonin, which intensifies itch sensation. Blocking serotonin's communication with nerve cells may help break the itch-scratch cycle.
A recent study highlights the dangers of women delaying medical attention for heart symptoms, citing a higher likelihood of severe or advanced stage treatment options being limited. Women often attribute symptoms to other possibilities and exhibit an optimistic bias, waiting longer to seek care than men.
A randomized trial found ibuprofen to be a safer and more effective option for managing fracture pain in children, with fewer adverse events compared to oral morphine. The study involved 134 children aged 5-17 and concluded that ibuprofen remains a viable therapy for outpatient management of children's fracture pain.
Researchers at Temple University Health System found that patients with non-cardiac chest pain experienced improved pain tolerance and reduced symptoms when treated with dronabinol. The study suggests a potential new approach for treating this condition, which affects an estimated 200,000 Americans annually.
A new study by Case Western Reserve University found that moderate sedation is used to calm anxiety in over half of patients, with fear of needles being the second most common reason. The study provides a guideline for when to use moderate sedation, but raises concerns about endodontist training and certification.
A study of 320 women finds that peak and end levels of pain experienced during childbirth are strong predictors of recalled pain, while duration of labor is not. Additionally, receiving an epidural may influence women's memory for labor pain, with those who received epidurals remembering lower levels of pain.
Researchers found a strong connection between the pelvic floor muscles and the glutes in the brain, highlighting the interconnected nature of the body. This discovery may help identify the causes of chronic pelvic floor pain and improve treatments for incontinence.
Research finds sleep disturbances are independently associated with pain and depression in osteoarthritis patients, while disability is not linked. High pain levels exacerbate depression in individuals with poor sleep, highlighting the vicious cycle of OA distress.
Researchers at the University of California, San Diego School of Medicine have discovered that T-cells are activated by a pain receptor called TRPV1 channel. The study shows that this receptor helps regulate intestinal inflammation in mice, suggesting a potential new target for treating certain autoimmune disorders.
A new study found that IBS patients process pain signals from the gut abnormally, with depressed patients showing reduced central pain inhibition. Depression may contribute to the development or maintenance of disturbed pain processing in IBS.
Researchers found that Montmorency tart cherry juice lowered blood uric acid levels and increased specific anthocyanin compounds, which may help alleviate joint pain and inflammation associated with conditions like gout. The study also detected increased C-reactive protein in the bloodstream after consuming tart cherries.
A new study from the University of Melbourne found that acupuncture did not improve chronic knee pain in patients older than 50. The research, published in JAMA, involved 282 participants who received either real or sham acupuncture for 12 weeks.
A study published in JAMA found that acupuncture did not improve chronic knee pain or function in patients over 50 years old. While acupuncture showed modest improvements in pain at short-term follow-up, these benefits were not sustained at one year.
A new study by Henry Ford Health reveals that pain can disrupt sleep in patients undergoing total hip replacement or knee replacement surgery, leading to longer hospital stays. The study found that better pain control could improve sleep duration for these patients.
The USPSTF recommends intensive behavioral counseling to reduce risky sexual behaviors among all sexually active adolescents and adults at risk for STIs. Chlamydia and gonorrhea screening is recommended for young women under 24 and older women at increased risk, including pregnant women.
By adopting a 'Just-in-Time' training and inventory process, researchers reduced patient wait times by 175 minutes and improved resident preparation, leading to better on-time performance and reduced pressure on clinic faculty.
A study found that single fraction radiation therapy (SFRT) is equally effective as multiple fraction radiation therapy (MFRT) in improving patients' pain, function, and quality of life, including for those with excluded characteristics. The results support the generalizability of prior randomized controlled trials to real-world practice.
A randomized phase II trial found that Manuka honey was not effective in reducing esophagitis pain during radiation therapy for lung cancer patients. The study enrolled 163 patients who received either standard supportive care or Manuka honey supplements, but showed no significant differences in pain levels.
A new study published in Psychological Science suggests that sharing painful experiences can lead to increased cooperation and bonding within groups. Researchers found that participants who underwent painful tasks reported higher levels of group bonding and were more willing to cooperate with their group members.
A study found that tear gas exposure can lead to respiratory symptoms such as coughing, chest pain, and phlegm production in protesters, with the effects lasting up to two weeks. Researchers also discovered that people living near protest areas were exposed to harmful lung health effects from tear gas use.
Researchers at Duke University have made a surprising discovery about the role of calcium in pain sensation using Caenorhabditis elegans worms. Calcium flow through pain-sensing channels helps worms adapt to repeated painful stimuli by desensitizing them, suggesting a potential survival advantage.
Researchers at Stanford University School of Medicine have discovered a non-addictive and safe-for-the-heart compound called Alda-1 that reduces inflammatory pain. The compound was found while searching for the reason behind moderate drinkers' less-severe heart attacks.
Scientists have found that people with irritable bowel syndrome (IBS) have a defective immune system, which is the primary reason for ongoing gut pain and reduced effectiveness of pain treatments. This groundbreaking research could lead to more targeted treatments for IBS sufferers.
Young people's feedback reveals oppressive culture around anal sex with little regard for consent or pleasure. Researchers call for more open discussion on the importance of mutuality in anal sex.
A Mayo Clinic study found that 1 in 5 patients who went to the ER with gallbladder pain were sent home to schedule surgery, but returned within a month needing urgent surgery. Younger and older patients, as well as those with other health problems, are likelier to need emergency gallbladder removal.
The American College of Physicians recommends a full-night polysomnography test for diagnosing obstructive sleep apnea. A computer model predicts that new therapies will make chronic hepatitis C a rare disease by 2036. Physical therapy and corticosteroid injections provide equal relief from shoulder pain and disability, with MPT patien...
A study found that depressive symptoms and pain in dialysis patients were associated with increased hospitalization rates, emergency department visits, and mortality. The findings suggest that treating these symptoms could improve patient health and reduce healthcare costs.
A study found that acupuncture significantly improved the quality of life for early-stage breast cancer patients taking aromatase inhibitors by reducing fatigue, anxiety, and depression. The intervention led to a significant reduction in these symptoms, with effects persisting for at least four weeks after treatment.
Researchers found that diverticulitis patients suffer from chronic symptoms such as anxiety, depression, bloating, and abdominal pain, which can significantly impact their quality of life. The study aims to develop a screening tool to better assess the long-term impact of diverticulitis.
A new study by Aarhus University reveals that one in three young people experience knee pain between the ages of 12 and 19. The pain often persists even after two years, with 55% of adolescents with Patellofemoral Pain Syndrome still suffering from knee pain after two years.
A recent study published in JAMA Dermatology found that nearly 36.9% of skin cancer lesions are accompanied by itching, while 28.2% involve pain. Non-melanoma skin cancers are more likely to be associated with itch or pain.
A new study in the Journal of Consumer Research found that consumers are less satisfied with purchases when they have no money left, but are more satisfied when they come into funds. Brands can increase customer satisfaction by running promotions during times of low budget availability.
A study published in Neural Regeneration Research found that intrathecal bumetanide increases NKCC1 expression and decreases KCC2 expression in spinal cord neurons of rats with incisional pain. This suggests that intrathecal bumetanide may have analgesic effects through inhibition of NKCC1.
Researchers found that adding glucocorticoid to local anesthetic epidural injections provided minimal or no additional pain relief and physical limitations improvement. Corticosteroids may have caused increased satisfaction but also more adverse events, calling into question their routine use.
Research reveals one in three severely affected adults with ME in England have no access to local specialist services. Specialist adult ME/CFS services in the NHS provide little to no service to severely affected patients due to lack of funding, leaving them housebound and dependent on carers.
A recent study reveals that over one third of knee replacement surgeries in the US were deemed inappropriate, citing variation in knee pain and functional loss. The findings emphasize the need for standardized patient selection criteria among medical professionals to ensure effective use of this procedure.
Pediatric researchers identified gene variants that affect a child's need for pain-control drugs, suggesting personalized medicine for pain control. The study found associations between specific gene variants and increased postoperative pain in children.
A new study in the Journal of Consumer Research suggests that focusing on oneself can help individuals overcome distractions and stay committed to their goals. When participants were seated in a cubicle facing a mirror, they were more likely to eat M&Ms when thinking about abstract goals, such as improving their health.
A study led by Priscille Brodin and Laurent Marsollier found that the toxin mycolactone from Mycobacterium ulcerans limits the transmission of pain signals to the brain. This mechanism may lead to the development of new analgesics.
Research by Culum Brown suggests that fish are intelligent, social creatures capable of complex behaviors such as learning, cooperation, and tool use. The study concludes that fish should be afforded protection similar to other vertebrates, considering their pain perception and sentience
The American Society of Anesthesiologists (ASA) has identified five tests and procedures commonly performed in anesthesiology that may not be necessary, potentially saving patients time, money, and preventing harm. These recommendations include avoiding baseline laboratory studies, cardiac testing, pulmonary artery catheters, blood tra...
Ultrasound-guided injections of growth factors-containing platelet-rich plasma (PRP) have been shown to be no more effective than saline injections in treating recently developed epicondylitis, also known as tennis elbow. However, pain scores decreased significantly over the course of the trial.
A recent study of over 10,000 patients found that men tend to feel more pain after undergoing major surgery, while women experience higher levels of pain after minor procedures. The research suggests that the type and severity of surgery play a significant role in shaping pain perception.
Research at Euroanaesthesia meeting found that children exposed to indoor coal-burning stoves and/or second-hand tobacco smoke experience higher postoperative complications and excessive pain after tonsillectomies. Elevated carboxyhaemoglobin concentrations were linked to increased pain sensitivity and more frequent use of painkillers.
Researchers found that bicyclists tend to be in the best mood, followed by car passengers and drivers, while bus and train riders experience negative emotions. The study suggests improving transit riders' emotional experience may be as important as traditional service features.
A new tick-borne bacterium, Neoehrlichia, has been linked to six cases of disease in Sweden, posing a significant risk to people with weakened immune systems. Researchers found that those over 50 years old with haematological or rheumatic diseases undergoing immunosuppressive treatment are most vulnerable.
A study published in JAMA found that an endoscopic procedure did not reduce disability due to pain following gallbladder removal. Patients with abdominal pain after cholecystectomy underwent either sphincterotomy or a placebo treatment, and the results showed no significant difference in successful outcomes between the two groups.
A new study found that a home-based walking program significantly improved walking ability in patients with clogged leg arteries, even 12 months after the program started. The program reduced symptoms of peripheral artery disease (PAD) and increased walking distance.
A study published in JAMA Network found that physical therapy did not significantly improve pain or function in adults with hip osteoarthritis. However, the treatment group reported more adverse events, which were relatively mild.
Researchers discovered that squid with increased vigilance after injury outlive their less vigilant counterparts due to enhanced predator avoidance. This finding challenges conventional views on pain and sensitization mechanisms.
A phase III clinical trial shows that non-invasive magnetic resonance guided focused ultrasound treatment relieves pain and improves function for most patients with bone metastases. Patients responded well to treatment, with 64 percent experiencing either no pain or a significant reduction in their pain within several days of treatment.
A recent Mayo Clinic study found that nerve damage after hip surgery may be caused by inflammation, rather than mechanical factors. The study identified key signs for physicians to look out for, including delayed onset of neuropathy and severe pain.
A large-scale study found that patient satisfaction with postoperative pain treatment is linked to perceptions of improvement and the patient-caregiver relationship. Patients who feel involved in their care experience higher levels of satisfaction.
An international team of pain researchers found that male experimenters' scent, caused by pheromones secreted from armpits, can produce a stress response in mice and rats, making them less sensitive to pain. This discovery may contribute to the reliability of rodent research studies.
A study by Fernanda Cristofori and colleagues found that 4.4% of children with irritable bowel syndrome (IBS) had celiac disease, compared to 0.3% in those without IBS. The prevalence was highest among IBS patients, who had four times the risk of developing celiac disease.
Researchers at King's College London have identified new pain relief targets that could help chemotherapy patients who suffer from persistent pain. The discovery was made by investigating how pain occurs in nerves and found that the immune system plays a key role in causing pain.
Researchers develop a prototype of the world's first intelligent prosthetic liner to measure pressure and pulling forces at the interface between a patient's stump and prosthesis. The device aims to provide accurate measurements for optimal socket fit, reducing pain and discomfort for amputees.
Research presented at EuroHeartCare 2014 found that visualizing a safe place reduced operative pain in patients undergoing ablation of atrial fibrillation. Patients who used visualization during the procedure were in pain less often and asked for fewer painkillers, with perceived pain intensity possibly also reduced.
A computer vision system can distinguish between real and faked expressions of pain more accurately than humans, with an 85% accuracy rate. This ability has potential uses in uncovering pain malingering and detecting deceptive actions in various fields.