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Octapharma's prothrombin complex concentrate, Balfaxar®, receives FDA approval for warfarin reversal in urgent surgery & invasive procedures

Octapharma's Balfaxar, a prothrombin complex concentrate, has received FDA approval for the urgent reversal of acquired coagulation factor deficiency induced by vitamin K antagonist therapy. The product demonstrated effective hemostasis in 94.6% of patients and was non-inferior to comparator Kcentra.

SourceYankee Public Relations·TypeObservational study·DateJul 26, 2023

Dedicated older people’s emergency department reduces wait times

A new study found that a dedicated older people's emergency department at Norfolk and Norwich University Hospital reduced wait times by 20% compared to the main emergency department. Patients treated under this initiative received earlier frailty assessments within 34 minutes of arrival, leading to fewer hospital admissions.

SourceUniversity of East Anglia·JournalJournal of Emergency Medicine·TypeRandomized controlled/clinical trial·DateJul 19, 2023

New AEM systematic review examines head imaging abnormalities in patients with acute delirium in the emergency department

A systematic review of geriatric ED patients with delirium reveals that 16% of older adults presenting with altered mental status have acutely abnormal head imaging findings. Focal neurological deficits greatly increase the risk of abnormal head CTs, while anticoagulation is not associated with these abnormalities.

SourceSociety for Academic Emergency Medicine·JournalAcademic Emergency Medicine·TypeSystematic review·DateJun 30, 2023

Brain stimulation may prove helpful to acute stroke patients, pilot study suggests

A pilot study suggests that high-definition cathodal transcranial direct current stimulation (HD C-tDCS) may be beneficial for acute ischemic stroke patients. In the study, patients who received HD C-tDCS showed improved blood flow and a significant rescue of threatened brain tissue, compared to those in the sham group.

SourceUniversity of California - Los Angeles Health Sciences·JournalJAMA Network Open·TypeRandomized controlled/clinical trial·DateJun 21, 2023

‘Concerning’ CT scans may cause unnecessary hospitalization for some pulmonary embolism patients

Researchers found that 'concerning' CT imaging results were associated with lower clinical outcomes and shorter hospital stays in low-risk patients with acute pulmonary embolism. This suggests that emergency physicians may be managing these patients differently, leading to unnecessary hospitalizations.

SourceMichigan Medicine - University of Michigan·JournalJAMA Network Open·TypeData/statistical analysis·DateJun 15, 2023

Study shines new light on old drug for trauma care

A new study has found that the drug tranexamic acid significantly improves survival rates among severely injured patients, with approximately four extra survivors for every 100 treated with the medication. However, the long-term outcomes of care and quality of life remain a concern, highlighting the need for further research.

SourceMonash University·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateJun 14, 2023

Groundbreaking findings bring hope for faster and better recovery after stroke

Researchers have developed an effective treatment that accelerates recovery after stroke by modulating astrocyte reactivity and cortical connectivity. The treatment, which involves administering a molecule called C3a in nasal drops, has shown positive results in mice with stroke, offering new hope for faster and better recovery.

SourceUniversity of Gothenburg·JournalJournal of Clinical Investigation·TypeExperimental study·DateJun 8, 2023

Tweets showed increasing loneliness among emergency medicine doctors during COVID-19

A study analyzed tweets from nearly 500 emergency medicine physicians, finding a significant increase in expressions of loneliness, anger, and anxiety during the pandemic. Positive themes took a dive, while negative emotions dominated, with loneliness increasing by up to 17% compared to pre-pandemic years.

SourceUniversity of Pennsylvania School of Medicine·JournalJAMA Network Open·TypeData/statistical analysis·DateJun 1, 2023

First aid: drones make a difference

A Eurac Research-led team tested drones' effectiveness in locating and providing first aid to injured people in difficult-to-access terrain. The study found that drone-assisted rescue operations reduced treatment time by 30% and saved critical minutes in cases of traumatic injuries and cardiac arrest.

SourceEurac Research·JournalThe American Journal of Emergency Medicine·TypeExperimental study·DateJun 1, 2023

Increasing effectiveness of home healthcare in Japan

A study published in the Journal of the American Geriatrics Society found that home healthcare clinics, especially enhanced ones, provide better emergency and end-of-life care than general clinics. This research suggests a shift towards more effective home care support for an aging population in Japan.

SourceUniversity of Tsukuba·JournalJournal of the American Geriatrics Society·DateJun 1, 2023

CHOP researchers comprehensively assess the safety of using your head in youth soccer

Researchers from Children's Hospital of Philadelphia found that repeated soccer headers equivalent to a throw-in did not cause immediate neurophysiological deficits for teens. However, oblique headers resulted in higher levels of angular head motion, suggesting proper training is necessary to reduce the risk of injury.

SourceChildren's Hospital of Philadelphia·JournalJournal of Biomechanical Engineering·TypeObservational study·DateMay 24, 2023

SAEM publishes new guideline for treatment of acute dizziness and vertigo in the emergency department

The Society for Academic Emergency Medicine has released a new clinical practice guideline for the treatment of acute dizziness and vertigo in emergency departments. The guideline is based on evidence-based recommendations and aims to improve patient care by reducing unnecessary imaging and promoting logical, algorithmic approaches.

SourceSociety for Academic Emergency Medicine·JournalAcademic Emergency Medicine·DateMay 11, 2023

Bleeding after image-guided breast biopsies: Discontinuing vs. maintaining antithrombotic therapy

A study of 5302 patients found no significant difference in bleeding events between those temporarily discontinuing and maintaining antithrombotic therapy during image-guided breast biopsies. The findings support the safety of continuing antithrombotic therapy, but counsel patients on bruising risk.

SourceAmerican Roentgen Ray Society·JournalAmerican Journal of Roentgenology·TypeImaging analysis·DateMay 10, 2023

U.S. Department of Veterans Affairs offers unlimited opportunities for emergency physicians

The U.S. Department of Veterans Affairs (VA) health system provides a promising career path for emergency physicians, offering competitive salaries and various opportunities for growth and development. The VA's focus on excellent care, education, and research provides a supportive environment for medical professionals to thrive.

SourceSociety for Academic Emergency Medicine·JournalAcademic Emergency Medicine·TypeCommentary/editorial·DateMay 5, 2023

Growing number of states provide coverage for outpatient hemodialysis for undocumented immigrants

A growing number of states have implemented policies to cover outpatient hemodialysis for undocumented immigrants with kidney failure. This expansion may be due to increased awareness of poor outcomes with emergency hemodialysis and advocacy efforts. The move towards covering dialysis in all 50 states is called for by experts, who also...

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeData/statistical analysis·DateApr 24, 2023

Achieving prevention and health, rather than more healthcare

Researchers found deaths from gallstone disease increased in younger populations and those with Medicaid after Medicaid expansion, highlighting the need for proactive prevention over reactive emergency care. A new healthcare model emphasizing primary care and prevention is proposed to address these inequities.

SourceRutgers University·JournalJournal of Surgical Research·TypeData/statistical analysis·DateApr 23, 2023

Study finds that child victims of violence face long-term psychological effects

A study found that young adults who experienced gunshot, stab, or assault wounds as children have significantly higher rates of post-traumatic stress disorder (PTSD) than the general population. Ten respondents screened positive for probable PTSD, and nearly 17% reported persistent symptoms related to their injury.

SourceUniversity of Rochester Medical Center·JournalJournal of Pediatric Surgery·TypeObservational study·DateApr 19, 2023

Study provides evidence that peer-support groups can be beneficial in reducing healthcare worker stress and burnout

A pilot study found that peer-support groups for emergency department physicians during the COVID-19 pandemic reduced symptoms of distress, depression, and burnout. The study's results suggest that this low-cost intervention could be beneficial for healthcare workers in stressful situations.

SourceRegenstrief Institute·JournalJournal of the American College of Emergency Physicians Open·DateApr 18, 2023

Preventing a measles outbreak: steps taken by London hospital to protect patients and staff potentially exposed to the virus

A London hospital recently took swift action to contain a potential measles outbreak, highlighting the importance of vaccination and prompt contact tracing. The hospital identified nine patients at high risk, including pregnant women and those with severe immunosuppression, and administered post-exposure prophylaxis to those not immune.

Optimizing sepsis treatment timing with a machine learning model

A new machine learning model estimates optimal treatment timing for sepsis, taking into account vital signs and lab test results to predict patient survival. The model was trained on a dataset of over 14,000 individuals with sepsis and showed improved outcomes when actual treatment matched the recommended timeline.

SourceOhio State University·JournalNature Machine Intelligence·TypeComputational simulation/modeling·DateApr 6, 2023

Costs of natural disasters set to spiral with continued rise in CO2 and global temperature, study shows

A study by Beth Israel Deaconess Medical Center found that climate change-related natural disasters have increased since 1980 and cost the US over $2 trillion in recovery costs. The analysis suggests that rising CO2 levels and temperatures will lead to more frequent and severe disasters, with exponentially increasing costs.

SourceBeth Israel Deaconess Medical Center·JournalJournal of Climate Change·DateApr 6, 2023

Lifesaving drug for severe bleeding after childbirth could be made accessible for all, study suggests

Researchers from the London School of Hygiene & Tropical Medicine found that intramuscular administration of tranexamic acid (TXA) is safe and quickly reaches therapeutic concentrations in pregnant women. Oral TXA was also well-tolerated but took an hour to reach therapeutic blood concentrations.

SourceLondon School of Hygiene & Tropical Medicine·JournalBritish Journal of Obstetrics and Gynaecology·TypeRandomized controlled/clinical trial·DateApr 5, 2023

Buprenorphine initiation in the ER found safe and effective for individuals with opioid use disorder who use fentanyl

A multi-site NIH study shows that less than 1% of people with opioid use disorder experience withdrawal when starting buprenorphine in the emergency department. The findings provide strong evidence for safe and effective buprenorphine treatment, even for those using stronger opioids like fentanyl.

SourceNIH/National Institute on Drug Abuse·JournalJAMA Network Open·DateMar 30, 2023

State incentive program improves initiation of medication treatment for opioid use disorder after emergency visit

A statewide incentive program in Pennsylvania is associated with a 50% improvement in initiating medication-assisted treatment for opioid use disorder among Medicaid-enrolled patients. The study found that the program increased prescription fills for buprenorphine and substance use disorder treatment within a week of emergency departme...

SourceUniversity of Pittsburgh·JournalJAMA Health Forum·DateMar 24, 2023