Articles tagged with Risk Factors
Researchers identified novel genetic associations between AD and modifiable risk factors, including high HDL cholesterol concentrations and systolic blood pressure. These findings may inspire new drug targets and improved prevention strategies for AD.
A new study found an initial decline in diabetes mellitus plus cardiovascular disease-related mortality, but it reversed from 2014 to 2019. The researchers emphasized the need for primary prevention of diabetes and early diagnosis to prevent cardiovascular complications and mortality.
The number of deaths worldwide from ischemic stroke increased from 2 million in 1990 to more than 3 million in 2019, with an expected increase to nearly 5 million by 2030. Lifestyle factors such as smoking and high blood pressure are identified as major contributors to the rising stroke rate.
A study found that muscle fat accumulation, known as myosteatosis, is associated with a higher risk of major adverse events and death in asymptomatic adults. The presence of muscle fat was comparable to the mortality risk associated with smoking or type 2 diabetes.
A Pharmacy PhD student from the University of Huddersfield has won a prestigious award to present her research on how community pharmacies can contribute to preventing suicide in low and middle-income countries, particularly in Nigeria. She aims to raise awareness of suicide and train pharmacists to recognize signs and risk factors.
A new study found that managing cardiovascular disease (CVD) risk factors can help preserve physical function in older adults. The research, led by Dr. Shivani Sahni, showed that vascular measures are associated with grip strength and change in gait speed.
Researchers developed a computational approach to predict diabetic kidney disease using DNA methylation markers from a blood sample. The model can use this information to assess current and future kidney function, enabling early detection and prevention of kidney disease in people with type 2 diabetes.
The statement highlights enormous inequities in stroke care, leading to significant gaps in functional outcomes for historically disenfranchised groups. Upstream interventions, such as policy changes and place-based initiatives, are crucial to address these disparities.
A Cochrane review found that individual-level stress management interventions, such as cognitive behavioral training and exercise, can reduce stress in healthcare workers for up to a year. The long-term effects of these interventions remain unknown, highlighting the need for further research.
A large study found that adults with obstructive sleep apnea were more likely to experience long-term symptoms of COVID-19 than those without the condition. Adults with both sleep apnea and COVID-19 were up to 75% more likely to develop long COVID, according to researchers.
A new study found that overweight boys tend to have lower testicular volume, putting them at risk for infertility in adulthood. The research suggests that weight loss could help patients avoid infertility later in life.
A new study found that being overweight or obese during early and middle adulthood increases the risk of gastrointestinal cancers in later life. The research also suggests that frequent aspirin use does not modify this increased risk.
A study by UMC Utrecht shows that corona patients can measure their blood oxygen levels at home using a pulse oximeter, feeling safe and experiencing more control. This method does not increase GP visits or hospitalization but contributes to relieving caregivers and keeping healthcare affordable.
Researchers developed a predictive model to identify tumor biomarkers of cachexia in lung cancer patients. The study used machine learning to build a muscle loss prediction model based on muscularity, clinical data, and the transcriptional profile from the tumor microenvironment.
Researchers found that women with denser breasts who developed cancer had slower declining density over time. The study suggests using past history of density in addition to current estimates to better understand risk levels and potentially identify which breast is at risk.
The new FRAXplus beta version offers a more user-friendly platform to refine risk factor information, allowing clinicians to explore the impact on individual patients. The tool provides helpful features such as saved data and export options to facilitate sharing.
The study found that vaccine type significantly impacts the immune response to COVID-19, with Pfizer and Moderna offering a stronger antibody response than Johnson & Johnson. Age, sex, BMI, and smoking status also affect vaccine effectiveness, with smokers experiencing a 240% lower response.
Recent cluster analyses identify novel risk stratification concepts to better implement precision medicine in clinical practice. Metabolically unhealthy individuals, regardless of weight, face a higher CVD risk compared to obese, metabolically healthy peers.
Research highlights unique effects of Asian American subgroups on heart disease and Type 2 diabetes risk. Variations in cardiovascular risk among Asian Americans indicate the need for individual subgroup data to better understand health risks.
Researchers at NIH have identified large-scale DNA changes, known as structural variants, that contribute to dementia risk. These variants were found in samples from patients with Lewy body dementia and frontotemporal dementia.
A Chinese Medical Journal review highlights the health hazards of air pollution, particularly from fine particulate matter (PM2.5), which is associated with increased risks of cardiovascular disease, hospitalization, and respiratory mortality. The study suggests that reducing PM2.5 levels through government interventions and individual...
A recent study found that exposure to antibiotics before age 5 triples the risk of pediatric IBD, while a Western diet high in sugars and ultra-processed foods increases the risk, and lower socioeconomic status provides protection. Conversely, having more siblings, being exposed to pets, and consuming vegetables reduce the risk.
New research shows that people with bipolar disorder or depression are more likely to be hospitalized if their verbal memory is poor. The study found an approximately 84% increased risk of admission to a psychiatric ward due to impaired verbal memory.
A study found that declines in racial disparities in COVID-19 mortality rates were largely due to increases in mortality among White individuals, rather than decreases in non-Hispanic Black and Hispanic populations. The shift from urban to rural areas also contributed to the decline.
A recent NIH study reveals that young men with cannabis use disorder are at a higher risk of developing schizophrenia. The study analyzed health records data from over 6 million people in Denmark and found that as many as 30% of schizophrenia cases among young men aged 21-30 might have been prevented by averting cannabis use disorder.
Researchers have found four key red flags for early-onset colorectal cancer, including abdominal pain and rectal bleeding, which can indicate an increased risk in younger adults. Early detection through timely endoscopy and follow-up is crucial to improve survival rates.
A study analyzing 34,000 people found that lowering sclerostin levels may increase the risk of heart attack, stroke, and type 2 diabetes. The research suggests that strategies to minimize potential impact on heart attack risk are needed.
Researchers analyzed data from over 20,000 US adults, finding that those who lost at least 5% of their body weight showed higher diet quality and more moderate physical activity. However, the study also found that many individuals relied on unsustainable non-evidence-based approaches for weight loss, highlighting the need for a paradig...
While smoking rates, physical inactivity, and heavy alcohol consumption declined, obesity prevalence increased, and cervical cancer screening declined between 2019 and 2021. Disparities by racial/ethnic and socioeconomic status persisted, highlighting the need for targeted interventions.
Strokes can be largely prevented through education and lifestyle changes, such as moving more, healthy eating, and managing blood pressure. The American Stroke Association is launching a digital tool to educate people on stroke warning signs and risk factors, particularly for diverse populations.
More than half of stroke survivors develop cognitive impairment within a year, with 1 in 3 at risk for dementia. Early screening and comprehensive care are advised to support stroke survivors with cognitive impairment.
A cohort study of 196 people treated with tecovirimat found that HIV status did not impact treatment outcomes. Only 22% of participants experienced nonsevere adverse effects, and 4 serious adverse events occurred, with 3 being persons with HIV. The findings contradict previous uncertainty about HIV's role in mpox acquisition.
A study supported by the National Institutes of Health found that younger women are nearly twice as likely to be rehospitalized after a heart attack as men. The disparity is largely due to higher rates of risk factors such as obesity and depression among women, which contribute to more adverse outcomes.
A study found that young women are more likely to experience adverse outcomes and rehospitalization after a heart attack, with non-cardiac hospitalizations showing the most significant disparity. Researchers highlight the need for public awareness and sex-specific post-heart attack care.
Research from Edith Cowan University found that lower grip strength and slower timed-up-and-go tests were significant risk factors for presenting with dementia. The study suggests that incorporating muscle function tests into dementia screening could help identify high-risk individuals who may benefit from primary prevention programs.
A new study by St. Jude Children's Research Hospital found that children with supportive environments fared better than those living in neighborhoods with economic hardship. Higher EHI scores were associated with lower cognitive abilities and greater decline after treatment, especially in math skills.
The American Heart Association scientific statement rates how closely popular dietary patterns align with its guidance for heart-healthy eating. The statement evaluates 10 categories of diets, scoring them from 31 to 100 based on their alignment with the guidance, with some diets receiving high scores while others need improvement.
A new study published in the Journal of the American Heart Association found that U.S. adults who experienced workplace discrimination were more likely to develop high blood pressure. The research, which analyzed data from over 1,200 adults, suggests that work-related stress due to discrimination may be an emerging risk factor for card...
Two recent studies conducted at the University of Eastern Finland found that renal hyperfiltration (RHF) is associated with an increased risk of mortality, independent of diabetes mellitus. A lower kidney filtration rate threshold may serve as a more precise measure for defining RHF.
Researchers found deaths from gallstone disease increased in younger populations and those with Medicaid after Medicaid expansion, highlighting the need for proactive prevention over reactive emergency care. A new healthcare model emphasizing primary care and prevention is proposed to address these inequities.
A study of 5,000 patients with breast cancer found that women from disadvantaged neighborhoods had shorter breast cancer-specific survival rates compared to those from advantaged areas. The findings suggest potential unaccounted mechanisms, including social determinants of health and access to care.
Researchers developed a system to grade and predict surgical complications by analyzing 51,030 cases. The system uses Bayesian network modeling to identify key risk factors and clusters, enabling precise prediction of surgical outcomes.
Researchers found that participants with lower written health literacy experienced longer delays in initiating postoperative radiation therapy. The study controlled for demographic and clinical factors, highlighting the importance of health literacy in cancer care.
Researchers found that women with prediabetes after pregnancy had aberrations in their early pregnancy blood serum metabolomic profile, including higher concentrations of small HDL particles. These metabolic changes predicted prediabetes at postpartum and were associated with increased risk of type 2 diabetes.
Individuals who experienced depression during pregnancy were more likely to be diagnosed with cardiovascular disease within two years after giving birth. The study found a significant higher risk of developing six major cardiovascular conditions, including heart failure and ischemic heart disease.
A new online tool, CogDrisk, has been found to be effective in assessing dementia risk, providing a personalized report for patients and GPs. The tool uses a combination of statistical methods and modifiable risk factors to predict dementia risk, including physical activity, obesity, high blood pressure, smoking, and poor diet.
A Mayo Clinic study found that people with severe obesity and a genetic pathway variant are at increased risk of developing hypertension. The research identified 168 carriers of the MC4R variant, who had a higher risk of hypertension compared to noncarriers.
A University of Maryland study found that LGBTQ+ teens experience more suicidal thoughts and self-harm ideation on days when they face high levels of minority stress, including microaggressions and internalized stigma. The study suggests that daily interventions are crucial to reducing these risks.
A UK Biobank study found that cancer survivors may be at long-term increased risk of cardiovascular disease, regardless of traditional risk factors. Those with previous breast or blood cancers were found to have the greatest risk, with significant changes in heart size and function detected on MRI scans.
Researchers discuss rapamycin's potential to delay cancer onset by slowing cell proliferation and tumor progression. The mTOR pathway is involved in both cancer and aging, making rapamycin a promising chemopreventive agent.
A new study from the University of Eastern Finland identified 12 cell types involved in CAD pathogenesis. The genetic risk factors for CAD take effect via smooth vascular muscle cells, which change their phenotype as the disease progresses.
Researchers found that removing ovaries during a benign hysterectomy increases the risk of hospitalization for cardiovascular disease in premenopausal women, but not necessarily for cancer. The study supports current recommendations to conserve ovaries in premenopausal patients at low risk for ovarian cancer.
Researchers found that primary school children spend more time on screens, exercise less, and eat unhealthy food during the holidays. Adding structure to their days with regular activities and limited screen time can encourage healthier behaviours.
A machine learning model has been developed to predict a patient's risk for a sleep disorder using demographic, lifestyle, physical exam results, and laboratory values. The model identified depression, weight, age, and waist circumference as the greatest predictors of a sleep disorder diagnosis.
The study reveals that female youth charged with prostitution had significantly higher prevalence rates of physical abuse and lower likelihood of living with parents, while males were more likely to live with their parents. Education and training are crucial for professionals to identify sex trafficking victimization and reduce misiden...
A study published in Diabetologia found that bariatric surgery can regenerate damaged nerves and improve metabolic risk factors related to diabetes. Peripheral neuropathy, a condition affecting over 30 million Americans, showed improvements two years after the procedure.
The new American Heart Association scientific statement emphasizes the importance of including non-biological factors and social determinants in CVD risk assessment for women. These factors include economic stability, neighborhood safety, education level, and access to quality healthcare, which disproportionately affect women from dive...
Researchers developed a model that predicts which species are at risk of becoming threatened or extinct based on climate change, human population growth, and land use patterns. The study aims to shift conservation efforts from reactive to proactive, enabling the protection of species before they reach threatened status.
A new UC Davis study found that high blood pressure in young adulthood is associated with lower regional brain volumes and worse white matter integrity, both factors linked to dementia. The research also showed sex differences in the negative brain changes, with men exhibiting stronger effects than women.
The University of Texas at El Paso will study the role of obesity and inflammation in pancreatic cancer development, a disease with high mortality rates. The grant aims to develop targeted treatments and preventives, potentially transforming understanding of pancreatic cancer.