Articles tagged with Biochemical Analysis
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Scientists at the Max Planck Institute have uncovered how ExoY toxin becomes activated in human cells by binding to actin filaments, leading to devastating enzymatic activity. This discovery sheds light on a crucial molecular mechanism that underlies the pathogenicity of various toxins.
Researchers from Tokyo University of Science developed a self-powered diaper sensor that monitors urine sugar levels, providing an alternative biomarker for blood sugar monitoring. The sensor uses a biofuel cell powered by glucose in the urine, detecting sugar levels within 1 second and simplifying caretaking tasks.
Researchers repurpose cancer drug PLX3397 to combat sarcoma's growth and spread in animal models. The treatment inhibits CSF-1/CSF-1R signaling, reprogramming tumor-associated macrophages and stimulating immune cell infiltration.
A faster and cheaper COVID-19 test kit has been validated by Simon Fraser University researchers, offering an alternative to existing tests. The microchip-based test can provide accurate results in 30 minutes and requires significantly less reagent usage.
The co-planar optoelectrowetting device allows for individualized and parallel droplet actuation, increasing microfluidic input/output system integration configurations while achieving faster droplet speeds. The open-top design enables easier access to droplets from above, improving the performance of the device.
Researchers developed an AI-powered imaging-based tool to estimate hemoglobin levels using a microfluidic chip and automated microscope. The system was validated with a high correlation coefficient of 0.99, meeting regulatory standards. This innovation could revolutionize medical diagnostics by reducing costs and laboratory footprint.
Scientists at Northern Arizona University are developing a new test technology using Single Molecule Surface Enhanced Raman Spectroscopy to detect SARS-CoV-2 virus. The method aims to overcome challenges of existing tests, including false negatives and high costs.
Researchers at IBM and Polytechnique Montreal have developed a novel method to solve the dispersion problem in portable diagnostic systems. By stretching a water drop into a long ribbon-like shape, they can reduce the flow rate of the liquid locally, allowing for precise biochemical measurements with minimal user intervention.
Researchers created a biosensor for detecting prostate cancer recurrence with high sensitivity and low cost. The device, like a home pregnancy test, provides immediate results and can help improve patient outcomes.
Researchers found similar patterns of diagnostic laboratory tests across five countries, despite differences in poverty levels and disease prevalence. The top 25 most common tests were common everywhere, with biochemical tests being the lowest priced.
A golden head centipede can subdue a caged mouse in under 30 seconds by injecting an estimated 30 μl of crude venom containing SsTx. The peptide toxin strongly inhibits KCNQ4 channels, controlling pulmonary vascular tone and arterial tension, leading to vasoconstriction and cardiovascular effects.
In a concerning study, nearly 500 Bangladeshi children aged 9-12 tested positive for recent second-hand smoke exposure. The results reveal alarming rates of SHS exposure among Bangladeshi children, with 95% showing evidence of biochemically validated exposure.
Researchers from University of Cambridge find that ordinary people left homesteads to become nomadic herdsmen or took up arms with tribes. Meanwhile, some Huns adopted settled agriculture, enjoying a more stable lifestyle.
Researchers have developed a new brute force technique to test thousands of biochemical reactions at once, allowing them to quickly find optimal conditions. This breakthrough enables faster development of diagnostic tests and sheds light on molecular behavior in test tube conditions.
Researchers are breeding barley to make it more resistant to drought and heat, helping farmers avoid yield loss due to climate change. By identifying key molecular switches, they aim to create crops that can efficiently manage water under extreme weather conditions.
A simple test can rapidly detect preeclampsia, a deadly pregnancy-related condition affecting 5-8% of pregnancies worldwide. The Congo Red Dot (CRD) diagnostic test has an accuracy rate of 86%, identifying high blood pressure and protein in the urine.
Researchers have developed a highly sensitive test to detect infectious diseases like hepatitis C and superbugs. The new method can pick up tiny traces of metabolites, proteins or DNA fragments, making it 10,000 times more sensitive than other detection systems.
Researchers at Penn Vet used blood plasma and serum in glucometers for more accurate measurements than whole blood, finding results closely aligned with a gold standard machine. This simpler method may soon be adopted for human patients relying on glucometers.
A new blood test has been developed to diagnose early onset Alzheimer's disease, detecting changes in the brain two decades before symptoms appear. The test shows high accuracy in predicting AD risk and has the potential to improve treatment options.
Scientists developed a novel biochemical assay and algorithm to detect fetal chromosomal abnormalities in maternal blood, achieving high accuracy and efficiency compared to existing methods. The new approach has the potential to reduce unnecessary invasive testing and improve screening for Down syndrome and Edwards syndrome.
A study published in The Lancet shows that smokers are twice as likely to quit when receiving motivational text messages compared to placebo texts. Biochemical testing confirms the effectiveness of the txt2stop intervention, which doubled smoking quit rates.
A new study published in ACS' Journal of Proteome Research found that people with symptoms of potential celiac disease may not be 'potential' patients at all. The study suggests that these individuals have the same distinctive metabolic fingerprint as those with full-blown disease who benefit from gluten-free diets.
Current prenatal biochemical screening tests only detect half of chromosomal abnormalities, including trisomies and deletions. This limitation emphasizes the importance of counseling patients on the limitations of these tests to make informed decisions about invasive diagnostic testing.
Patients with subclinical Cushing syndrome experience significant clinical improvement after adrenalectomy, including improved diabetes and hypertension. The study highlights the benefits of surgery for some patients with large adrenal tumors who suffer from hormonal disorders.
Researchers have developed a new way to track neuropsychiatric symptoms in lupus using magnetic resonance spectroscopy (MRS), which measures biochemical changes in the body. The study found that MRS can detect changes in metabolites, such as glutamate and glutamine, that correlate with behavioral tests.
Researchers have developed a digital magnetofluidics method that enables precise analysis of biological fluids using nanoscale surface patterns. This technology holds promise for improving medical diagnoses, environmental safety, and public security by reducing testing time and costs.
Researchers screened 2000 anonymous surgical tonsillectomy specimens for the presence of rogue prion protein causing vCJD. No positive cases were identified, but a national large-scale prospective prevalence study is necessary to determine true community infection rates.
A recent study published in Alcoholism: Clinical & Experimental Research found that energy drinks like Red Bull do not improve physical performance when consumed with alcohol. The researchers surveyed Brazilian nightclub-goers and found that the combination of energy drinks and alcohol did not reduce depressant effects or increase stim...
Engineers at Ohio State University have developed a patent-pending technology that automates the ELISA biochemical test on a compact disc, significantly reducing the time required for manual testing. The CD-based system detects a sample of rat antibody in just one hour, using only one-tenth the usual amount of chemicals.