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When FMD hits a family, abdominal aortic aneurysms may too

Researchers discover a shared genetic basis between fibromuscular dysplasia (FMD) and abdominal aortic aneurysms (AAA), with males more likely to develop AAA when a family member has FMD. The study suggests that screening for AAA in male relatives of patients with FMD may be beneficial, along with established guidelines.

SourceMichigan Medicine - University of Michigan·JournalCirculation Genomic and Precision Medicine·TypeData/statistical analysis·DateDec 1, 2022

Long-standing genomic mystery about the origins of introns explained in new study

A new study led by UCSC scientists suggests that introners are the source of most introns across species, providing a plausible explanation for their vast majority. The researchers found evidence of introners in 5.2% of surveyed eukaryotic species and suggest they may be a fundamental mechanism driving genomic complexity.

SourceUniversity of California - Santa Cruz·JournalProceedings of the National Academy of Sciences·DateNov 28, 2022
SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Powerful new tool to advance genomics, disease research

UVA researchers developed a new tool to analyze genetic data, reducing noise and bias in cancer diagnosis. The tool uses mathematical modeling to identify patterns in chromatin, helping scientists detect tiny numbers of disease cells.

SourceUniversity of Virginia Health System·DateNov 22, 2022

Personalising whole genome sequencing doubles diagnosis of rare diseases

A new study by UCL researchers found that tailoring whole genome sequencing analysis to individual patients can double the diagnostic rates of rare diseases. The personalised approach increased the diagnostic rate from 16.7% to 31.4%, detecting potential disease-causing variants in a further 3.9% of patients.

SourceUniversity College London·JournalNature Communications·TypeExperimental study·DateNov 7, 2022

Ancient DNA analysis sheds light on the early peopling of South America

Researchers used DNA from two ancient human individuals to unravel the deep demographic history of South America, providing new genetic evidence supporting existing archaeological data. They also discovered migrations along the Atlantic coast for the first time and found evidence of Neanderthal ancestry within ancient genomes.

SourceFlorida Atlantic University·JournalProceedings of the Royal Society B Biological Sciences·TypeComputational simulation/modeling·DateNov 1, 2022

Complex regulation controls mediator of cancer growth

The study reveals how the activating partner PI5P interacts with two different regions of regulatory protein UHRF1, showing its role in modulating complex proteins. This finding could breathe new life into the search for UHRF1-directed medicines.

SourceKing Abdullah University of Science & Technology (KAUST)·JournalScience Advances·DateOct 9, 2022
Apple AirPods Pro (2nd Generation, USB-C)

Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

Improvements for Man and Machine in Scientific Publishing

The use of Frictionless Data enhances both machine readability and human engagement with scientific outputs, turning articles into dynamic entities. Interactive figures enable readers to directly interact with data points, making the publication process more efficient and reproducible.

SourceGigaScience·JournalGigabyte·TypeComputational simulation/modeling·DateOct 5, 2022

Repeats are key to understanding humanity's genome

Researchers fill in gaps in Human Reference Genome, discovering repetitive sections are a major source of human variation and genetic diversity. The Telomere-2-Telomere project reveals complex architectural features with significant consequences for understanding human evolution and biological function.

SourceUniversity of Connecticut·JournalScience·TypeData/statistical analysis·DateMar 31, 2022

How can the computer chip predict the future of gene synthesis?

Researchers used the history of microchip development to predict advancements in synthetic biology, citing potential for exponential growth in transistors on a single computer chip. The study suggests that synthesizing an artificial human genome could cost approximately $1 million and simpler applications like custom bacteria could be ...

SourceUniversity of Cincinnati·JournalScientific Reports·TypeMeta-analysis·DateMar 3, 2022
Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

People in the Philippines have the most Denisovan DNA

Researchers found Philippine Negrito ethnic group, Ayta Magbukon, possess the highest level of Denisovan ancestry in the world. Their Denisovan DNA is up to 46% greater than that of Australians and Papuans.

SourceCell Press·JournalCurrent Biology·TypeObservational study·DateAug 12, 2021

Long search finds grain of hope in the glume

Researchers at the John Innes Centre identified a key gene controlling grain elongation and glume characteristics in Polish wheat, which could lead to improved productivity and sustainability in wheat production. The discovery highlights the importance of understanding genetic control of agronomic traits for major crops like wheat.

SourceJohn Innes Centre·JournalThe Plant Cell·DateMay 19, 2021

Tweaking corn kernels with CRISPR

Researchers at Cold Spring Harbor Laboratory have successfully applied CRISPR to increase corn kernel numbers by targeting promoter regions that regulate gene activity. This technique holds promise for increasing crop yields per acre and making agriculture more sustainable.

SourceCold Spring Harbor Laboratory·JournalNature Plants·DateFeb 22, 2021

Dana-Farber study advances understanding of rare sarcoma

Scientists at Dana-Farber Cancer Institute discovered how an abnormal protein misdirects gene expression in cells, contributing to the growth of sarcoma tumors. The researchers found that a small segment of the SS18-SSX fusion protein binds to nucleosomes, leading to aberrant activation of genes.

SourceDana-Farber Cancer Institute·JournalNature Structural & Molecular Biology·DateAug 3, 2020
Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Software locates sugarcane genes of interest

Brazilian researchers developed a software program called Polyploid Gene Assembler (PGA) to map specific portions of plant DNA, saving at least two orders of magnitude compared to mapping the whole genome. The technique uses publicly available data from related grasses to locate genes of interest for plant breeders.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalDNA Research·DateMay 15, 2019

Peanut genome sequenced with unprecedented accuracy

The study provides a detailed understanding of the peanut plant's genomic history and the molecular mechanisms underlying its growth and development. Researchers have identified potential leads for improving crop resilience to diseases and pests, including geographic origin information and DNA swapping patterns.

SourceUS Department of Agriculture - Agricultural Research Service·JournalNature Genetics·DateMay 1, 2019

Scientists call for unified standards in 3D genome and epigenetic data

Leading scientists propose guidelines for shared standardized validation of 4D nucleome data sets and models to address rapid development of methods and increasing complexity of data. The initiative aims to ensure proper characterization, validation, and sharing of information, enhancing our understanding of genome dynamics.

SourceCenter for Genomic Regulation·JournalNature Genetics·DateOct 30, 2018
Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

The highly complex sugarcane genome has finally been sequenced

The sugarcane genome has been sequenced using a novel method that leverages colinearity with the sorghum genome, enabling molecular screening techniques for breeding and biomass production. The reference sequence obtained is of high quality, revolutionizing genomic and genetic approaches for sugarcane species.

SourceCirad·JournalNature Communications·DateJul 11, 2018

MSU lands $4.8 million NSF grant to improve corn

Researchers will focus on controlling phenolics, compounds that protect plants from pathogens and adapt to environmental changes. The project aims to decipher the genetic secrets of corn's complex genome, expected to consist of 50,000 genes.

SourceMichigan State University·DateFeb 28, 2018
Sky-Watcher EQ6-R Pro Equatorial Mount

Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.

First detailed decoding of complex finger millet genome

Researchers have successfully decoded the complex genome of finger millet, a staple food in India and Africa, revealing over 62,300 genes. The new data holds promise for improving crop resilience to drought and enhancing nutritional content, addressing food security concerns globally.

SourceUniversity of Zurich·JournalDNA Research·DateSep 4, 2017

Sat nav for bread wheat uncovers hidden genes

Scientists have created the most accurate navigation system for the bread wheat genome, allowing researchers to analyze its genes more easily than ever before. The system includes detailed annotation of over 100,000 wheat genes, revealing previously hidden genes and improving crop yields.

SourceEarlham Institute·JournalGenome Research·DateApr 18, 2017
Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

The human genome: A complex orchestra

Researchers discovered that genetic variation impacts multiple, separated gene regulatory elements simultaneously, revealing a harmonized and synergistic behavior. This study sheds light on fundamental aspects of genome biology and its role in complex diseases such as cancer and diabetes.

SourceUniversité de Genève·JournalCell·DateAug 20, 2015

Clemson, international team crack genetic code of Upland cotton

A groundbreaking achievement has deciphered the genetic makeup of Upland cotton, a crucial step toward developing superior lines with advanced fiber elongation and strength. The research also sheds light on polyploidy genetics and its significance in crop plants.

SourceClemson University·JournalNature Biotechnology·DateApr 20, 2015
DJI Air 3 (RC-N2)

DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

Simplifying SNP discovery in the cotton genome

Researchers developed a strategy to identify and genotype SNPs in complex cotton genomes using genotyping-by-sequencing. The approach employs Stacks software to enrich for orthologous DNA fragments, allowing for detection of polymorphisms between individuals.

SourceBotanical Society of America·JournalApplications in Plant Sciences·DateMar 31, 2015

Broad, MIT researchers reveal structure of key CRISPR complex

Researchers have revealed the structure of the Cas9 complex, a key part of the CRISPR-Cas system used for genome editing. The study provides a detailed picture of the complex, enabling researchers to refine and engineer the tool to accelerate genomic research and bring it closer to treating human genetic disease.

SourceBroad Institute of MIT and Harvard·JournalCell·DateFeb 13, 2014

After the human genome project: The human microbiome project

The Human Microbiome Project is a major scientific effort to study the microbial communities within humans, with potential insights into diseases and disorders. The study, published in The FASEB Journal, provides a comprehensive reference set of microbiome specimens and lays a foundation for future research.

SourceFederation of American Societies for Experimental Biology·JournalThe FASEB Journal·DateFeb 28, 2013

Study finds prioritizing rather than canvassing entire plant genome may lead to improved crops

Researchers at Kansas State University have developed a new method for prioritizing genes in plant genomes, which has been shown to improve the likelihood of finding critical genes controlling traits such as drought tolerance and grain yield. By applying genetic-analysis methods used to study humans, scientists were able to identify a ...

SourceKansas State University·JournalGenome Research·DateDec 4, 2012
Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

Major breakthrough in deciphering bread wheat's genetic code

Scientists have unlocked key components of the genetic code of bread wheat, providing a strong foundation for accelerating wheat improvement through advanced molecular breeding and genetic engineering. The analysis enables breeders to select plants with desirable combinations of genes using genetic landmarks in the wheat genome.

SourceBiotechnology and Biological Sciences Research Council·JournalNature·DateNov 28, 2012

Liverpool scientists decipher genetic code of wheat

Researchers at the University of Liverpool have deciphered the genetic code of wheat, enabling breeders to produce varieties with disease resistance and drought tolerance. The team's breakthrough analysis of over 90,000 genes will help farmers adapt to changing environmental conditions.

SourceUniversity of Liverpool·JournalNature·DateNov 28, 2012

New insights into a virus proteome

Researchers have identified over 700 novel proteins in the herpesvirus genome, many of which are surprisingly small and complex. This discovery provides new insights into the biology of the herpesvirus and highlights the importance of analyzing the products actually produced from the genome.

SourceMax-Planck-Gesellschaft·JournalScience·DateNov 23, 2012
GQ GMC-500Plus Geiger Counter

GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Analyzing complex plant genomes with the newest next-generation DNA sequencing techniques

New DNA sequencing techniques enable plant scientists to analyze complex genomes, revealing new insights into plant diversity and evolutionary history. Targeted enrichment methods facilitate the study of specific genes and regions, accelerating discovery in crop production, ecosystem health, and understanding plant diversity.

SourceBotanical Society of America·JournalAmerican Journal of Botany·DateFeb 24, 2012

Simpler woodland strawberry genome aids research on more complex fruits

The University of Illinois has sequenced the genome of the woodland strawberry, a close relative of the apple, to aid in researching complex fruits. This will help improve strawberry quality and characteristics, as well as enhance the development of desirable traits in apples.

SourceUniversity of Illinois College of Agricultural, Consumer and Environmental Sciences·JournalNature Genetics·DateApr 4, 2011
Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

New insights into the software of life

The FANTOM consortium's findings provide a major step towards identifying all protein building blocks, using multiple mechanisms to produce different forms of proteins in mammals. The research also explores the importance of non-coding RNA in development and evolution, revealing why complex organisms evolved beyond simple genes.

SourceResearch Australia·JournalScience·DateSep 2, 2005

Mouse genome much more complex than expected

The mouse genome is more complex than expected, with over 60% of mRNAs not encoding proteins. The discovery challenges the traditional view that genes contain specific protein blueprints.

SourceUniversity of Bonn·JournalScience·DateSep 1, 2005
Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Fugu fish sequencing project potential boon to gene hunters

Scientists have embarked on a collaborative effort to sequence the Fugu fish genome, offering valuable insights for identifying genes in the human genome. The project aims to utilize the Fugu genome's compact size and minimal 'junk DNA' to facilitate gene discovery.

SourceDOE/Lawrence Berkeley National Laboratory·DateOct 25, 2000

Drosophilagenome sequence completed

The Drosophila genome sequence has been completed, providing valuable insights into human diseases and animal development. The sequence data reveals homologues for 60% of known genetic flaws causing disease in humans and 70% of genes involved in human cancers.

SourceHoward Hughes Medical Institute·JournalScience·DateMar 23, 2000