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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Rice neuroscientists to build state-of-the-art neural recording system

Chong Xie and his team at Rice University have won a $2.9 million grant from the National Institutes of Health to develop an implantable neural electrode system for high-resolution, long-term neural recording and stimulation. The project aims to improve the resolution of existing devices by increasing the density of neurons sampled.

Meta Quest 3 512GB

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Brainless memory makes the spinal cord smarter than previously thought

Researchers at RIKEN Center for Brain Science discovered neural circuitry in the spinal cord that enables brain-independent motor learning and recall. The study found two critical groups of neurons: one necessary for new adaptive learning and another for recalling adaptations once learned.

How the brain coordinates speaking and breathing

Researchers found a brainstem region that regulates breathing rhythm, ensuring breathing remains dominant over speech. The circuit also involves premotor neurons in the hindbrain region called the retroambiguus nucleus (RAm), which are activated during vocalization.

WVU researcher making sense of brain circuits with $1.6M NSF grant

A WVU researcher is studying corollary discharge circuits in fruit flies to better understand how the brain integrates sensory information and coordinate movement. The goal of this research is to shed light on human disease and human performance, with potential applications for improving fighter pilot safety.

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When a task adds more steps, this circuit helps you notice

A new study by neuroscientists at MIT's Picower Institute finds that the anterior cingulate cortex (ACC) and motor cortex collaborate to update understanding and behavior when a task requires more steps. The ACC helps M2 adjust to new rules, but reduced activity leads to increased negative outcome encoding cells' activity in M2.

Extra “eye” movements are the key to better self-driving cars

A new AI system uses artificial neural networks to recognize objects more accurately and stably, despite changing visual inputs. The system mimics human eye movements to improve machine vision capabilities, reducing errors in self-driving cars and other applications.

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Treatment for Parkinson’s could now get even better

A new study from the University of Copenhagen has made significant breakthroughs in treating Parkinson's disease by targeting specific neurons in the brainstem. By stimulating excitatory neurons in the caudal area of the pedunculopontine nucleus, researchers were able to restore normal walking function in mice with Parkinson's symptoms.

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Duetting songbirds 'mute' the musical mind of their partner to stay in sync

Researchers studied the brain activity of singing male and female plain-tailed wrens, discovering that they synchronize their duets by inhibiting the song-making regions of their partner's brain. This inhibition allows for a seemingly telepathic performance, with the birds becoming a single entity through sensory linkages.

Neuronal circuits for fine motor skills

A study published in Nature reveals that a specific region of the brainstem is responsible for various fine motor activities of the forelimbs. The researchers used optogenetic and viral methods to mark neurons and observe their activity, identifying four neuronal subpopulations correlated with specific functions.

Researchers link genes and motor skills development

A study co-led by John H. Martin found that genetic mutations in the Bax/Bak pathway affect neural motor skills development in infant mice. The researchers discovered that disruptions in this pathway hinder the formation of proper connections between the brain's motor cortex and spinal cord.

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The tortoise and the hare of spinal neural circuits

Researchers found that practicing movements at different speeds improves certain nerve functions, particularly for patients with spasticity after a stroke or spine injury. The study suggests tailoring physical therapy routines to reflect the type of neural circuit controlling the movement for optimal rehabilitation outcomes.

New role for motor neurons discovered

Researchers at Karolinska Institutet have discovered a new role for motor neurons in influencing rhythmic movements. Motor neurons directly control the recruitment of upstream excitatory interneurons via gap junctions, indicating they are not passive recipients of signals from interneuronal circuits.

Balancing old and new skills

The MIT model suggests that neurons constantly change connections to explore many possible solutions, but with a balance between hyperplasticity and low signal-to-noise ratio. This allows the brain to learn new skills while retaining previously learned ones, especially if they are not similar.

Brain wiring quiets the voice inside your head

Researchers developed a diagram of the brain circuitry enabling interplay between motor system and auditory system. This discovery could provide insight into schizophrenia and mood disorders, where individuals hear voices others do not.

New brain circuit sheds light on development of voluntary movements

Researchers at Duke University Medical Center have identified a new brain circuit controlling whisker movements in newborn mice. The circuit reveals how motor neurons integrate inputs from the LPGi region of the brainstem to enable voluntary whisking behaviors, shedding light on neural control of finger movements in humans.

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Reading ability protects brain from lead exposure

A study published in Neurology found that reading ability is a protective factor against the negative effects of lead exposure on the brain. Workers with higher reading levels showed less cognitive decline compared to those with lower reading abilities.