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New study reveals genetic drivers of early onset type 2 diabetes in South Asians

A new study from Queen Mary University of London has identified the genetic drivers of early onset type 2 diabetes in South Asians, revealing a strong link to lower insulin production and unfavorable body fat distribution. The research also sheds light on treatment responses, highlighting the need for precision medicine approaches.

SourceQueen Mary University of London·JournalNature Medicine·TypeObservational study·DateNov 26, 2024

Cause of the yo-yo effect deciphered

A study by ETH Zurich researchers has found that epigenetic markers in fat cells can lead to the yo-yo effect, where weight drops but returns. The researchers also found evidence of this mechanism in humans, suggesting that obesity can leave a lasting mark on gene expression.

SourceETH Zurich·JournalNature·TypeExperimental study·DateNov 18, 2024
SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

New study investigates link between fat and cancer

Researchers at Anglia Ruskin University are investigating the complex relationship between fat tissue and colorectal cancer. The study aims to enhance knowledge of the tumour microenvironment, uncover new molecules crucial for cancer growth, and develop more effective treatments.

SourceAnglia Ruskin University·DateNov 14, 2024

Study advances understanding of metformin effects on fetus

Metformin, a widely prescribed diabetes drug, may increase risks of obesity and diabetes in newborns when given to pregnant women. The study found that the drug accumulated in the fetal kidneys, liver, and other organs, leading to growth restriction, which has been linked to an elevated risk of obesity and insulin resistance in childhood.

SourceUniversity of Oklahoma·JournalAmerican Journal of Obstetrics and Gynecology·TypeExperimental study·DateNov 12, 2024

Scientists identify immune molecule that keeps metabolism in tune and on time

Researchers identify interleukin-17A as a key regulator of fat storage, carrying implications for addressing obesity and preventing wasting. The discovery highlights the interaction between the immune system and circadian rhythms, which may hold therapeutic potential for metabolic disorders.

SourceTrinity College Dublin·JournalNature·TypeExperimental study·DateNov 5, 2024
Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Measure of body roundness may help to predict risk of cardiovascular disease

A new study found that a high body roundness index over 6 years was associated with an increased risk of developing cardiovascular disease in adults older than 45. The study, published in the Journal of the American Heart Association, suggested that BRI may be a valuable predictor of cardiovascular disease risk.

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateSep 25, 2024

A simple blood test warns of possible cardiometabolic complications for children with obesity

A study from the University of Copenhagen detected lipid biomarkers in obese children that indicate a higher risk of developing type 2 diabetes, liver, and heart disease later in life. A one-year lifestyle intervention lowered these biomarkers, demonstrating the importance of early intervention for children with obesity.

SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalNature Medicine·DateSep 20, 2024

Abdominal fat linked to widespread chronic pain, especially in women

A study of 32,409 participants found a strong association between abdominal fat and chronic musculoskeletal pain, especially in women. Reducing visceral adipose tissue and subcutaneous adipose tissue may be key to managing chronic pain in multiple body sites.

SourceBMJ Group·JournalRegional Anesthesia & Pain Medicine·TypeObservational study·DateSep 10, 2024
AmScope B120C-5M Compound Microscope

AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

Experts call for routine measurement of lipoprotein (a) levels

High levels of lipoprotein (a) found in 20-34% of Polish patients with heart disease or at risk. Lp(a) measurements may be crucial in preventing cardiovascular diseases and atherosclerosis progression.

SourcePolskie Towarzystwo Lipidologiczne (Polish Lipid Association)·JournalProgress in Cardiovascular Diseases·TypeObservational study·DateAug 29, 2024

Does low lipoprotein(a) increase the risk of diabetes? New research suggests it does not

Researchers used genetic method Mendelian randomization to show high levels of fasting insulin cause reduction in Lp(a), rather than the other way around. Low Lp(a) is unlikely to be a risk factor for type 2 diabetes, independent of pre-existing hyperinsulinaemia and insulin resistance.

SourcePolskie Towarzystwo Lipidologiczne (Polish Lipid Association)·JournalCardiovascular Diabetology·TypeData/statistical analysis·DateAug 29, 2024

Obesity-induced inflammation increases the secretion of extracellular vesicles from adipose tissue

Research from the University of Eastern Finland found that obesity-induced inflammation increases the secretion of extracellular vesicles from human adipocytes, which may contribute to the detrimental health effects of obesity. Visceral adipose tissue secretes more extracellular vesicles than subcutaneous adipose tissue.

SourceUniversity of Eastern Finland·JournalJournal of Translational Medicine·DateAug 19, 2024
Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

A ketogenic diet could improve the response to pancreatic cancer therapy

Scientists discovered a way to kill pancreatic cancer in mice by combining a ketogenic diet with an existing cancer drug. The diet blocks the cancer's only source of fuel, allowing the drug to take effect and shrink tumors. This finding opens a new vulnerability for treating cancer with diet and personalized therapies.

SourceUniversity of California - San Francisco·JournalNature·DateAug 14, 2024

Swipe up! Health apps deliver real results en masse

A new study found that digital health tools can improve health and wellbeing by keeping people active, boosting steps, and improving diet and sleep. The research synthesised data from 206,873 people across 47 studies, indicating that electronic and mobile health interventions can help people achieve positive outcomes.

SourceUniversity of South Australia·Journalnpj Digital Medicine·TypeMeta-analysis·DateAug 13, 2024

$2.4 million grant helping MCG scientists better understand what happens to our skeleton as we age

Researchers are studying the role of stress hormones and mineralocorticoid receptors in bone health as we age. The goal is to understand how balance between these factors affects our skeletons. By investigating this complex relationship, scientists hope to develop new insights into osteoporosis and other age-related bone disorders.

SourceMedical College of Georgia at Augusta University·DateAug 1, 2024
GoPro HERO13 Black

GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.

The sooner the better: teaching healthy habits in elementary school reduces abdominal fat

A large-scale study published in JACC shows that promoting healthy habits in elementary school children can effectively reduce abdominal fat and obesity markers. The study found that early intervention, particularly during the first three years of school, was more effective than delayed interventions.

SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalJournal of the American College of Cardiology·TypeObservational study·DateJul 29, 2024
Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Research uncovers heart-protective eating patterns for type 1 diabetes

A six-year study found that consuming diets more closely aligned with the Mediterranean and DASH diets can lower levels of harmful blood markers and reduce cardiovascular disease risk. These dietary patterns emphasize plant-based foods, healthy fats, lean proteins, and low intake of processed foods and sugars.

SourceAmerican Society for Nutrition·DateJun 30, 2024

Building a blueprint of metabolic health – from mouse to human

Researchers developed a metabolic health score based on clinical parameters and used it to explore its genetic underpinnings in mice, validating findings in human data. The study identified two significant genetic regions linked to metabolic health and pinpointed candidate genes associated with metabolic traits.

SourceEcole Polytechnique Fédérale de Lausanne·JournalCell Systems·DateJun 11, 2024
Sky-Watcher EQ6-R Pro Equatorial Mount

Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.

Pennington Biomedical Research Center recruiting participants for lipedema research study

The Pennington Biomedical Research Center is conducting a clinical trial to better understand lipedema. Participants will undergo comprehensive assessments and imaging techniques to help advance medical knowledge related to chronic disease. Compensation of up to $475 is offered for participation in the three-month study.

SourcePennington Biomedical Research Center·TypeObservational study·DateJun 11, 2024

Marsupials key to discovering the origin of heater organs in mammals

Research from Stockholm University reveals that marsupials possess a not fully evolved form of brown fat, a crucial finding for understanding the origin and regulation of this heat-producing organ. The study suggests that the gene networks required to enable thermogenesis existed before the divergence of marsupials and placental mammals.

SourceStockholm University·JournalScience·TypeExperimental study·DateJun 6, 2024
Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Intermittent fasting shows promise in improving gut health, weight management

A new study highlights the benefits of intermittent fasting and protein-pacing on gut health, weight loss, and metabolic responses. Participants showed improved diversity of the gut microbiota, decreased symptoms of gastrointestinal problems, and increased beneficial microbes linked to a lean body type.

SourceArizona State University·JournalNature Communications·TypeRandomized controlled/clinical trial·DateMay 28, 2024

Proteomic signatures may indicate MRI-assessed liver fat

Researchers from Ben-Gurion University of the Negev have discovered a link between proteomic biomarkers and liver fat percentage, which may improve patient monitoring and therapy targeting for NAFLD. The study, conducted over 18 months, found that specific protein changes were independently associated with liver fat relative change.

SourceBen-Gurion University of the Negev·JournalHepatology·TypeRandomized controlled/clinical trial·DateMay 28, 2024
Nikon Monarch 5 8x42 Binoculars

Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

New study further illuminates ability of cancer drug to lower blood sugar

A new study reveals that a cancer drug can improve insulin sensitivity and lower blood glucose levels, but eliminating a specific gene related to fat metabolism worsens insulin resistance. The research highlights the interconnectedness of fat metabolism in organs and the need for simultaneous treatment of obesity and insulin sensitivity.

SourceUniversity of Oklahoma·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMay 23, 2024

Fat cells influence heart health in Chagas disease

Chronic Chagas Disease can cause irreversible heart damage due to the destruction of adipose tissue by Trypanosoma cruzi, releasing particles that induce dysfunction. The study reveals that adipome release regulates immunometabolic signaling and promotes inflammation in cardiac remodeling.

SourceHackensack Meridian Health·JournaliScience·TypeExperimental study·DateMay 20, 2024
Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

New cells could be key to treating obesity

Researchers have identified a population of mesothelial-like cells in omental adipose tissue that limit fat cell formation, offering new insights into the mechanisms underlying obesity. These cells secrete Insulin-like Growth Factor Binding Protein 2, which inhibits adipogenesis and regulates metabolic behavior.

SourceEcole Polytechnique Fédérale de Lausanne·DateMay 9, 2024
Apple AirPods Pro (2nd Generation, USB-C)

Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

Hyperspectral dark-field microscopy for rapid and accurate identification of cancerous tissues

Researchers have developed a new imaging technique that rapidly and accurately identifies cancerous tissues in breast samples. The method uses machine learning algorithms trained on hyperspectral dark-field microscopy data to pinpoint regions of invasive ductal carcinoma and invasive mucinous carcinoma.

SourceSPIE--International Society for Optics and Photonics·JournalJournal of Biomedical Optics·DateMay 8, 2024

New drug candidate reverses obesity in mice

Researchers at Karolinska Institutet have discovered a new class of drugs that block mitochondrial function and reverse diet-induced obesity, fatty liver, and diabetes in mice. The treatment increased fat metabolism, leading to drastic weight loss and restored glucose tolerance.

SourceKarolinska Institutet·JournalNature Metabolism·TypeExperimental study·DateApr 30, 2024

Understanding the cellular mechanisms of obesity-induced inflammation and metabolic dysfunction

The study reveals that TM4SF19 protein inhibits a pump in lysosomes, impeding macrophage clearance of dead cells. Macrophages lacking TM4SF19 demonstrate enhanced efficacy in clearing dead adipocytes, reducing weight gain and metabolic dysfunction. The findings may open new avenues for treating obesity and related metabolic disorders.

SourcePohang University of Science & Technology (POSTECH)·JournalNature Communications·DateApr 24, 2024
Garmin GPSMAP 67i with inReach

Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.

Abdominal obesity might predict risk of fecal incontinence

A study of over 7,500 US adults found that higher abdominal obesity, measured by waist circumference-to-height ratio, was associated with a higher risk of fecal incontinence. The researchers suggest that this may be due to increased intra-abdominal pressure and visceral fat-related inflammation.

SourceBrigham and Women's Hospital·JournalClinical Gastroenterology and Hepatology·TypeObservational study·DateApr 22, 2024

Weight training improves symptoms of anxiety and depression in old people, study confirms

A study published in Psychiatry Research confirms that weight training improves symptoms of anxiety and depression in old people. The analysis of over 200 articles identified the types of training most indicated for these cases, recommending exercises done three times a week with short sets and proper structure.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalPsychiatry Research·DateApr 10, 2024
CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

CMS121 mitigates aging-related obesity and metabolic dysfunction

Researchers found that CMS121 reduced body weight gain by 40% and improved glucose and lipid indexes in aging mice. The compound also showed anti-inflammatory effects and increased mitochondrial biogenesis, suggesting potential therapeutic applications for metabolic diseases.

SourceImpact Journals LLC·JournalAging-US·TypeExperimental study·DateApr 9, 2024

Toothed whale echolocation organs evolved from jaw muscles

New research at Hokkaido University reveals that acoustic fat bodies in toothed whales were once jaw muscles and bone marrow. The findings suggest an evolutionary tradeoff between auditory and feeding ecology, leading to the loss of chewing muscles and adaptation to echolocation.

SourceHokkaido University·JournalGene·TypeExperimental study·DateApr 8, 2024

The irony of smoking to stay thin: smoking increases belly fat

A new study found that both starting smoking and lifetime smoking may increase abdominal fat, especially visceral fat. Visceral fat is hard to see but raises the risk of serious illness. Researchers used genetic studies to determine whether smoking causes an increase in abdominal fat.

SourceSociety for the Study of Addiction·JournalAddiction·TypeData/statistical analysis·DateMar 21, 2024
Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Novel treatment strategy reduces inflammation and cardiometabolic risk in adolescents with obesity

A one-year interdisciplinary therapy program reduced inflammation and cardiometabolic risk in obese adolescents, improving insulin resistance and weight management. The semi-intensive model produced better results than previous intensive models, reversing hyperlipidemia and promoting energy balance.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalInternational Journal of Environmental Research and Public Health·DateFeb 21, 2024

Disrupted cellular function behind type 2 diabetes in obesity

A recent study published in PNAS suggests that impaired macrophage function plays a key role in the development of type 2 diabetes in obese individuals. The research found that collagen breakdown is handled by macrophages, which become deactivated in obesity and insulin resistance, leading to the accumulation of collagen fragments.

SourceUniversity of Gothenburg·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateFeb 1, 2024
Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

Study unveils a role of mitochondria in dietary fat processing

A recent study published in Nature reveals that mitochondrial dysfunction disrupts dietary lipid processing in enterocytes, leading to abnormal fat accumulation and impaired nutrient delivery. The findings provide new insights into the gastrointestinal symptoms of mitochondrial disease and may lead to novel therapeutic approaches.

SourceUniversity of Cologne·JournalNature·TypeExperimental study·DateDec 20, 2023

A spinal muscle’s size and shape is linked to body fat, according to new Concordia research

A new study by Concordia researchers found a strong positive relationship between percentage body fat and echo intensity, indicating more fat within the muscle. The study also revealed differences in lumbar multifidus characteristics between male and female athletes, with females having larger LMs than males.

SourceConcordia University·JournalFrontiers in Musculoskeletal Disorders·TypeImaging analysis·DateDec 13, 2023
DJI Air 3 (RC-N2)

DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

Holidays crank up kilos for Aussie kids

Research shows that Australian children are at risk of excessive weight gain and declining fitness during school holidays. The two-year study found that body fat increased at a faster pace and aerobic fitness declined faster than in-school periods. Promoting physical activities during holidays could help address unhealthy weight gain.

SourceUniversity of South Australia·JournalBMC Public Health·TypeCase study·DateDec 11, 2023

Chaperoning fat storage: the molecular basis of adiposity

A study by researchers from Osaka University found that HSP47, a collagen-specific molecular chaperone, is significantly expressed in fat tissue and correlates with body fat levels. High or low HSP47 expression was linked to high or low body fat levels in both humans and mice.

SourceOsaka University·JournalNature Communications·TypeExperimental study·DateNov 27, 2023

Hidden belly fat in midlife linked to Alzheimer’s disease

A study published at the Radiological Society of North America annual meeting found that higher amounts of visceral abdominal fat in midlife are associated with increased risk of Alzheimer's disease. The research also showed that this type of fat is linked to brain inflammation, which may contribute to the development of the disease.

SourceRadiological Society of North America·DateNov 20, 2023

Cycle of fasting and feeding is crucial for healthy ageing

Researchers found that older fish deviate from a youthful fasting and refeeding cycle, entering a permanent fasting state despite eating. Genetic activation of AMP kinase's γ1 subunit restored benefits of refeeding in old killifish, improving health and longevity.

SourceMax Planck Institute for Biology of Ageing·JournalNature Aging·TypeExperimental study·DateNov 13, 2023