Articles tagged with Endocrinology
A recent study published in the Journal of the Endocrine Society suggests a link between exposure to phthalates and elevated blood pressure during pregnancy. Pregnant women with higher levels of fragrance-associated phthalates were found to have higher systolic and diastolic blood pressure markers, increasing their risk of hypertensive...
The Lancet Diabetes and Endocrinology Commission on Obesity definition of obesity was found to have similar diagnostic accuracy as other definitions. The study compared the commission's definition with those from other reputable sources, including the World Health Organization (WHO) and the National Institutes of Health (NIH).
Researchers discovered a strong link between environmental variation and thyroid hormone signaling in reef fish, enabling them to adapt to changing habitats. The study found that habitat impacts development by altering gene expression and metabolic profiles, giving animals more flexibility when their environments change.
A Japan-wide study found that growth hormone therapy improves adult height in childhood stem cell transplant survivors with short stature. However, treatment responses were highly variable and influenced by transplant-related factors such as total body irradiation and chronic graft-versus-host disease.
A cross-sectional study examines state-level type 1 diabetes burden and pediatric endocrinology resource distribution in the US. The study found that type 1 diabetes incidence has increased over time, while pediatric endocrinology resources are not evenly distributed across states.
A study found that telemedicine is commonly used for problem-based primary care, particularly for children with endocrine or behavioral health issues. The availability of telemedicine may help increase appointment volume, making more patients accessible to care.
UC San Diego Health has been ranked as the top care facility in California and among the top 20 in the nation for eight medical specialties. The institution achieved this distinction through its patient-dedicated, collaborative spirit and commitment to delivering outstanding care.
The new position statement offers practical recommendations for the assessment, diagnosis, and management of PLO. It recommends individualized management, including pharmacological treatment where appropriate.
The IOF Musculoskeletal Rare Diseases Training Course bridges latest scientific advances with current clinical guidance, covering disorders-specific programs. Clinicians can access high-quality educational content at their own pace to deepen expertise in rare skeletal conditions diagnosis and management.
Researchers found that live sporting events stimulate oxytocin dynamics, leading to increased heart-rate synchrony among casual spectators. This physiological response is linked to greater enjoyment, unity with players and spectators, immersion, and intention to reattend future events.
A new position statement calls for systematic bone health optimization before joint replacement and spinal fusion surgery. Key findings include the progressive mechanical failure of bone-implant constructs resulting from compromised bone quality, particularly due to osteoporosis.
Mouse study uncovers how oxygen-sensing transcription factors regulate muscle physiology, improving glucose tolerance and producing erythropoietin. The findings suggest that selectively targeting each isoform can lead to different physiological outcomes.
A clinical trial has shown that setmelanotide, a new drug, can achieve significant weight loss in people whose weight has become dysregulated following treatment for a brain tumor. The treatment resulted in a 20% reduction in BMI, with participants experiencing substantial health benefits.
A new study from the University of Copenhagen suggests that longer sleep is linked to more stable blood sugar levels in healthy 18-year-olds, even among those with no previous health issues. The researchers tracked participants over two weeks and found a two-way relationship between sleep duration and blood sugar stability.
A new study reveals that excessive fibrin deposition drives chronic inflammation in diabetic periodontitis. A targeted peptide successfully stops this inflammation and promotes periodontal bone regeneration, offering a potential universal therapeutic strategy for various immune-mediated diabetic comorbidities.
A recent study found that women and individuals with minimal motivation to lose weight experienced greater weight loss on tirzepatide. The research also identified baseline clinical, demographic, and behavioral variables associated with weight loss trajectories over 12 months.
A recent study found that long naps may increase the risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD) in people with type 2 diabetes. MASLD is characterized by excessive fat buildup in the liver, which can lead to chronic disorders like NAFLD.
Clinical trials suggest that GLP-1s can improve testosterone levels and sperm quality in men with obesity-related low testosterone. The research also found that GLP-1s address the underlying effects of obesity on fertility. The studies showed no negative impact on hormones, sexual function, or sperm quality.
A study of 165,832 women found that later menarche is associated with an increased risk of tobacco use disorder and various conditions, including digestive issues, heart problems, and brain disorders. The researchers suggest a shift in perspective to recognize childhood influences as the primary cause of adult health problems.
A new study reveals that obesity is reshaping the global cardiovascular disease crisis, with heart disease now peaking in people aged 50-54 rather than the elderly. The study projects over 1.37 million premature cardiovascular deaths attributed to obesity by 2050, primarily in South Asia and low-income countries.
A study found that tirzepatide significantly increases brown adipose tissue activity and volume in premenopausal women with obesity. The medication also shows potential signs of converting white subcutaneous fat into more metabolically active 'beige' fat.
A retrospective cohort study found that menopausal hormone therapy significantly reduces the risk of low bone mineral density by 69% compared to non-users. This suggests that hormone therapy could be an effective way to prevent bone loss and lower fracture risks in women after menopause.
The first real-world study of fezolinetant found the treatment improved hot flashes, depression, and anxiety in women with menopausal vasomotor symptoms. In a study of 656 women, fezolinetant significantly reduced hot flash symptoms and showed benefits similar to those seen in clinical trials.
A study presented at ENDO 2026 found semaglutide was associated with a 15% reduction in bone fractures and greater weight loss compared to other anti-obesity medications. The results suggest that semaglutide may have beneficial effects on bone health in people with type 2 diabetes.
A study found that nearly 4 in 10 patients stopped GLP-1 medication within the first year and nearly two-thirds restarted therapy within two years. The researchers also identified sociodemographic, clinical, and provider-level predictors of discontinuation, including Medicaid or Medicare status, Black patients, and side effects.
A study of 336 mother-infant pairs found that breast milk and infant urine contained over 50 different chemicals, including BPA and phthalates, which can interfere with hormones during baby's development. These chemicals were detected in breast milk and urine up to 6 months after birth.
A study published by the Endocrine Society found that testosterone therapy was often prescribed without adequate diagnostic testing, highlighting opportunities for quality-improvement efforts. The research suggests that targeted interventions may be needed to improve guideline-concordant prescribing practices and prevent avoidable risks.
A new AI model analyzed 30 years of EHR data to identify patients with primary aldosteronism, a common cause of high blood pressure. The model correctly flagged over 90% of cases while missing fewer than 10%, suggesting it could improve screening for this condition.
Children who start puberty earlier than usual may not need the same level of testing or treatment, according to a new Endocrine Society Clinical Practice Guideline. The guideline suggests different approaches for various subgroups, including monitoring girls with slow progression and using simpler testing methods.
A nationwide study of over 5.7 million women aged 40 found a link between longer reproductive spans and an increased risk of thyroid cancer. The research also showed that hormone replacement therapy, especially for five years or more, was associated with a higher risk of developing the disease.
A study found that testosterone alone is not enough to prevent type 2 diabetes in older men; lifestyle interventions are crucial for improving blood sugar control and reducing obesity. Testosterone treatment can improve body composition and sexual desire, but its benefits diminish over time.
A comprehensive analysis of solid-organ transplant recipients found that both existing and new-onset diabetes significantly increase mortality risk. Organ transplant recipients who developed or have diabetes after surgery had a higher risk of death compared to those without diabetes, with kidney recipients having the highest risk.
A study presented at the Endocrine Society's annual meeting found that exposure to the plasticizer DEHP in early development can lead to increased anxiety-like behavior in adult male rats. The research suggests that humans exposed to endocrine disruptors before and shortly after birth may experience long-lasting behavioral changes.
The study found a significant increase in type 1 diabetes cases among Hispanic/Latino adolescents in Puerto Rico, from 10.1 per 100,000 in 2009 to 24.1 in 2021, with an average annual increase of 4.1%. This trend has important implications for patient care and public health.
Researchers found that eliminating sugar from a low-fat diet can lead to impaired glucose control, insulin resistance, and gut microbial imbalance. Balanced dietary carbohydrates are essential for supporting gut and immune homeostasis.
A study found that adults taking GLP-1 receptor agonist medications experienced significant decreases in daily step counts and moderate-to-vigorous physical activity, highlighting the need for targeted interventions to promote exercise alongside obesity treatment.
Researchers found a strong association between gut microbiome composition and bone health in patients with primary hyperparathyroidism. Bifidobacterium longum was identified as a key microbial driver of bone loss through immune-mediated mechanisms.
A three-year study reveals coral hormone cycles similar to humans', helping detect reproductive stress and informing reef conservation. Hormone levels were found to be influenced by sunlight, not heat, and distributed evenly throughout colonies.
The Mount Sinai Health System has opened the Carolyn Rowan Center for Women’s Health and Wellness, which brings together multidisciplinary clinical expertise, structured care pathways, and leading-edge research to deliver personalized, comprehensive care for women. The Center offers guided multi-visit experiences and coordinated care o...
Researchers found that the gut responds to protein deficiency by activating a fast neural circuit and a slower hormonal signal, which selectively changes dietary priorities. The study reveals a previously unknown gut-brain signaling system that rapidly alters feeding behavior in animals.
Researchers identified a vitamin K-dependent GAS6 pathway that controls osteoclast maturation and bone resorption in mice. Osteoblasts use Vitamin K signals to regulate osteoclast fusion via the GAS6 pathway.
The Capture the Fracture program has achieved a major milestone, identifying over one million patients with fragility fractures every year. This growth reflects increasing recognition of coordinated post-fracture care services as an essential component of modern hospital care.
The Endocrine Society and Keystone Symposia will host their first joint conference in October to explore discovery in cancer, diabetes, and cardiometabolic disease. The conference series aims to strengthen the exchange of scientific knowledge through coordinated programming, facilitating discovery and collaboration among researchers.
A phase 2 clinical trial found that burosumab safely restored normal phosphate levels and improved physical function in patients with severe fibrous dysplasia. Key findings include reduced pain, fatigue, and mobility impairment, as well as significant improvements in children's mobility and independence.
Polyendocrine Ovarian Syndrome (PMOS) impacts 13% of women, causing hormonal imbalance, insulin resistance, and chronic pain. Lifestyle interventions, particularly diet and exercise, show benefits for physical and mental health outcomes.
International experts in laboratory medicine, osteoporosis, and chronic kidney disease recommend ending routine reporting of albumin-adjusted ('corrected') calcium. The practice may misclassify patients and compromise care due to unreliable correction formulas and variability in local measurements.
A recent study published in Journal of Functional Foods found that paraprobiotics derived from Enterococcus faecalis FK-23 can protect against sperm toxicity caused by bisphenol A (BPA) exposure. The researchers observed improved sperm motility and reduced oxidative stress markers when rats received FK-23 despite BPA exposure.
The 28th European Congress of Endocrinology (ECE) 2026 brought together over 4,500 delegates from 111 countries to experience the latest endocrine research and developments. The Congress celebrated the Society's 20th Anniversary and featured groundbreaking studies on hormone disruption, bone development, insulin resistance, and polycys...
Research found that girls born to mothers with higher insulin resistance during pregnancy are more likely to have more abdominal fat at age 7. Maternal insulin resistance was not associated with body fat in boys, suggesting girls may be more susceptible to the mother's insulin resistance during late pregnancy.
Polyendocrine Metabolic Ovarian Syndrome (PMOS) is a complex hormonal disorder impacting 1 in 8 women globally, affecting weight, metabolism, mental health, skin, and the reproductive system. The name change aims to improve diagnosis and care for this previously misunderstood condition.
A new editorial by IOF members highlights the alarming high post-fracture mortality in Africa and emphasizes the need for a targeted, Africa-driven strategy. The authors propose five strategic priorities to build bone health into national health systems, education, and policy.
Research suggests that exposure to environmental pollutants in early life can negatively affect bone development. A study of 88 healthy infants found associations between certain endocrine-disrupting chemicals and lower bone mineral density, emphasizing the importance of protecting vulnerable windows during pregnancy and after birth.
The summit brought together endocrine leaders to identify opportunities to work closely together on increasing the visibility of endocrine health in policy decisions. Early findings from a workforce survey revealed challenges including long patient waiting times and retention concerns among early-career clinicians.
A new study has found that individuals with insulin-requiring type 1 and type 2 diabetes have a significantly higher risk of developing dementia compared to those without diabetes. The study, which examined over 1.3 million adults in South Korea, suggests that dementia risk is not the same for all types of diabetes.
The ECE 2026 brings together researchers and clinicians to share the latest endocrine research and developments. Key sessions include Plenaries, Symposia, Awards, Meet the Experts, Debates, and Oral Communications.
Italian researchers Anna Pilatone and Gabriella Milan won the Endocrine Society's 2026 Endocrine Images Art Competition with their image of a pre-adipocyte cell, highlighting the complexity of adipose tissue in obesity. The winning entry will be displayed at ENDO 2026 and featured in Endocrine News magazine.
A new study from the University of Virginia finds that next-generation GLP-1 drugs can alter brain circuits controlling motivation and reward. The research shows that these drugs not only suppress appetite but also influence how the brain values food, helping explain their effectiveness and side effects.
A NIH-funded study discovered that testosterone may play a key role in limiting brain tumor growth in men by suppressing inflammation and stress hormone production. Analysis of over 1,300 men with glioblastoma found that supplemental testosterone was significantly associated with improved survival rates.
The European Society of Endocrinology organizes World Hormone Day to educate the public about hormone-related health issues. Global endocrine disorders affect millions worldwide, emphasizing the need for proper hormone balance.
A new analysis of a major clinical trial found that vitamin D supplementation reduced diabetes risk in prediabetic adults with certain variations in the vitamin D receptor gene. The study suggests personalized medical care could delay or prevent diabetes onset for millions of Americans living with prediabetes.