Articles tagged with Endocrinology
The European Society of Endocrinology has released the EndoCompass Research Roadmap, a major new initiative to align research efforts and improve funding strategies for hormone-related health challenges. The roadmap identifies specific research needs across eight endocrine specialties and five cross-cutting areas.
People with higher muscle mass, as indicated by stronger grip strength, are less likely to develop organ damage or die from obesity. Building and maintaining muscle through weight training may be a practical way to identify individuals at risk and act early.
Researchers have found that GLP-1 therapies may help reduce alcohol and other substance use by modulating neurobiological pathways underlying addictive behaviors. The therapies, which are commonly used to treat diabetes and obesity, have shown encouraging results in early clinical trials.
Researchers discovered a new pathway that could help people with diabetes avoid dangerous hypoglycemia by restoring the function of delta cells. These cells, previously unknown to play a role in blood sugar regulation, release somatostatin to pause insulin production when necessary.
A new study found that over 40% of specialty clinics in the US turn away patients weighing 465 pounds or more due to lack of accessibility features. The study highlights a need for staff training on inclusive care and accommodations for patients with severe obesity.
A new clinical trial found that feeding blueberries to infants as their first solid food can reduce allergy symptoms and support long-term health. The study suggests early introduction of blueberries may improve infants' immune systems and gut health.
Researchers have identified a risk category called 'pre-prediabetes' that occurs years before standard criteria for prediabetes are met. This stage is characterized by severe insulin resistance and measurable cardiovascular disease, highlighting the need for early detection and treatment.
A new study published in Clinical Chemistry and Laboratory Medicine has developed a practical tool to support harmonization and quality improvement in vitamin D testing. The multicentre study evaluates the measurement uncertainty of various 25-(OH)D assays and their ability to detect physiologically relevant changes over time.
The Endocrine Society has recognized 12 exceptional endocrinologists with its 2026 Laureate Awards, honoring their groundbreaking research and clinical breakthroughs in treating hormone disorders. The winners include Robert M. Carey, Christopher Kevin Glass, Rebecca Reynolds, Samuel Klein, and Lisa B. Nachtigall, among others.
The International Osteoporosis Foundation identifies critical global barriers to osteoporosis care, including limited DXA scanning and outdated treatment criteria. The IOF advocates for a paradigm shift in bone health management worldwide, recognizing high fracture risk as a valid criterion for treatment and reimbursement.
A new review emphasizes the importance of both physical activity and reduced sedentary time for optimal skeletal health. Emerging evidence reveals that prolonged sitting and inactivity can harm bone health, even among regular exercisers.
Researchers discovered a brain-liver circuit that connects stress with increased glucose production, potentially linking to type 2 diabetes. Long-term elevations in glucose can cause hyperglycemia and increase the risk of developing type 2 diabetes.
A study by Professor Chunxiu Gong's team identified the clinical presentation of Cornelia de Lange syndrome (CdLS) and genetic alterations in Chinese pediatric patients. The researchers found that 12 patients presented with classic CdLS, while others showed global developmental delays and growth retardation.
A study by Mount Sinai-Duke University identifies specific DNA variants in the DENND1A gene that increase testosterone production in PCOS patients. This finding could lead to new therapies targeting the genetic source of elevated testosterone levels in PCOS, which is a common condition affecting reproductive-age women.
A recent study published in the Journal of the Endocrine Society found that skipping breakfast and having late dinners are associated with an increased risk of osteoporosis. Additionally, unhealthy eating habits were linked to other lifestyle risk factors such as physical inactivity, smoking, and insufficient sleep.
The International Osteoporosis Foundation has issued an updated joint position statement on managing aromatase inhibitor-associated bone loss in women with hormone-sensitive breast cancer. The guidelines incorporate recent clinical trials and systematic reviews to provide evidence-based treatment algorithms for assessing fracture risk ...
Extracellular vesicles play a crucial role in regulating oocyte maturation, follicular growth, and quality. In pathological conditions, EVs can disrupt communication, leading to impaired oocyte development and ovarian failure. Therapeutic EVs show promise in reversing ovarian pathologies by delivering functional molecules.
Researchers identify key apoptotic signaling pathways involved in glucocorticoid-induced osteonecrosis, including CD95/CD95L and PI3K/Akt survival pathways. They also highlight genetic biomarkers and novel therapeutic strategies, such as targeting specific molecular pathways with natural compounds.
The Mount Sinai Hospital has been listed among the nation's top 20 hospitals for care excellence by U.S. News & World Report for 2025-26, with top-10 rankings in five specialties and top-20 rankings in nine. The hospital was also rated High Performing in all 22 procedures and conditions assessed by U.S. News.
The Endocrine Society guideline suggests universal screening for primary aldosteronism in people with hypertension. This condition is associated with a higher risk of cardiovascular disease if left undiagnosed and untreated.
Adrenal hormone function was restored in animal studies using implantable cell therapy, demonstrating potential for a functional cure for primary adrenal insufficiency. The treatment also followed the animals' natural circadian rhythm and showed improved survival rates.
A novel AI-powered retina tracker, SMART, analyzes retinal images with near-perfect accuracy in under one second, offering hope for sight-saving screenings for diabetic retinopathy. The tracker expands access to high-quality retinal assessments globally, reducing vision loss from diabetic retinopathy.
A new mouse study suggests that watching others eat, especially palatable food, can cause overeating in the absence of hunger. The study found that satiated mice increased their intake of sucrose diet when observing fasted peers, but dopamine receptor inhibitors suppressed this behavior.
A new study found that anti-obesity medications can normalize testosterone levels in men with obesity or type 2 diabetes. This positive effect on reproductive health was observed after a 10% weight loss, with total and free testosterone levels increasing by 24%.
A study found that night shift work disrupts the body's internal timing, causing irregular reproductive cycles and hormonal imbalances. Women exposed to shiftwork-like light exposure had a higher risk of ovarian disruption, pregnancy complications, and difficult labor, even if they were not experiencing disrupted cycles.
Despite supply shortages and insurance coverage obstacles, patients taking GLP-1 medications achieve clinically significant weight loss when paired with intensive lifestyle interventions. The study found that consistent medication courses combined with lifestyle changes and support remain the most effective weight-loss program option.
A study published by The Endocrine Society found that obesity and early type 2 diabetes in adolescence can interfere with bone development, potentially increasing the risk of fractures and osteoporosis later in life. Researchers followed 48 teenagers for a year, finding that teens with obesity and type 2 diabetes showed less improvemen...
A new study by The Endocrine Society finds a strong link between acromegaly and an increased risk of various cancers, often at younger ages than expected. Patients with the rare growth hormone disorder had higher rates of certain types of cancer, including colon, gastric, breast, lung, ovarian, prostate, and blood cancers.
The guideline suggests screening women of reproductive age with diabetes for intent to conceive at every reproductive, diabetes, and primary care visit to ensure they receive appropriate preconception care. Women with diabetes who become pregnant are at risk for adverse pregnancy outcomes, such as miscarriages or birth defects, which c...
A study found that consuming aspartame, sucralose, glycyrrhizin and added sugars may increase the risk of early puberty in children, especially those with genetic traits. This association was strongest for central precocious puberty, a condition linked to emotional distress and metabolic disorders.
A novel AI-powered application has been developed to diagnose endocrine cancers with speed and accuracy, leveraging advanced deep learning architectures. The tool analyzes diverse medical data, including imaging scans and histopathology images, and demonstrated exceptional diagnostic accuracy in certain validation datasets.
A new study found that intermittent energy restriction significantly improved fasting blood glucose and triglycerides, while also increasing insulin sensitivity. The IER group showed the greatest advantages in reducing these markers compared to time-restricted eating and continuous energy restriction groups.
Cancer deaths linked to obesity have increased sharply in the US, especially among women and older adults, with sharp regional disparities. The study highlights the need for targeted public health strategies to address this growing public health crisis.
A study of over 7,600 Brazilian women found that early menarche increases risk for metabolic and heart problems, while late menarche may protect against obesity but increase certain heart issues. Understanding age at first period can help doctors identify high-risk patients and guide personalized screening and prevention efforts.
A study presented at the Endocrine Society's annual meeting found that socially isolated older adults are 34% more likely to have diabetes and 75% more likely to have poor blood sugar control. Social isolation is being recognized as a critical social determinant of health, highlighting its importance in caring for older patients.
A new study presents preliminary data suggesting that grandparents' exposure to endocrine-disrupting chemicals may impact the age when girls get their first period. The research found that certain chemicals in both mothers and fathers were linked to earlier puberty, with stronger effects seen in granddaughters.
A recent study found that oxytocin levels rise in response to stress-related sleep disruption, helping women experience less mood disturbance the next day. The study suggests oxytocin as a potential biological buffer during periods of hormonal and emotional vulnerability.
Research suggests that thyroid hormone treatment can improve gut health in individuals with hypothyroidism, particularly those with autoimmune thyroiditis. The study found a higher prevalence of SIBO in people with hypothyroidism compared to controls, which was mitigated by thyroid medication.
A small study found that consuming more protein may help prevent muscle loss in adults with obesity taking semaglutide, an anti-obesity medication. The researchers noted that older adults and women may be at higher risk for muscle loss, emphasizing the importance of preserving muscle during weight loss with this medication.
A recent study published by The Endocrine Society found that osteoporosis treatment after a fracture can decrease both hospitalization and mortality in people older than 80. Researchers analyzed data from 88,676 patients aged 80 and older who suffered a fracture due to bone deterioration or weakness caused by osteoporosis.
A study by The Endocrine Society reveals that children with growth hormone deficiency experience improved overall health and coping mechanisms when their caregivers report reduced stress, anxiety, and depression. Conversely, caregivers' emotional stability is associated with better outcomes for the child.
A long-term study of healthy men found that minimally elevated blood sugar levels can lead to declines in sperm movement and erectile function. The study suggests that lifestyle choices and medical interventions can help preserve or revive reproductive health in aging men.
A real-world study of 120 postmenopausal women found that using tirzepatide and menopause hormone therapy simultaneously led to superior total body weight loss percentage compared to using tirzepatide alone. This combined treatment also resulted in a higher percentage of participants achieving at least 20% weight loss.
Researchers found that tirzepatide reduced body weight and body fat by approximately 20% in mice, resulting in a significant reduction of tumor volume. The study suggests that this new anti-obesity drug may have a beneficial impact on breast cancer outcomes.
The Endocrine Society's new Scientific Statement identifies potential research directions to improve treatment options for people with type 1 diabetes. The statement highlights the need for population-based screening and more research into the causes of the disease.
A comprehensive review highlights the impact of anti-cancer treatments on bone health, increasing the risk of fractures and bone fragility. The International Osteoporosis Foundation advocates for a multidisciplinary approach to early screening and proactive bone-protective strategies.
A new hypothesis suggests that prenatal sex steroid hormones and placental function played a crucial role in shaping the human brain and its cognitive traits. This may have led to increased brain size and reduced competition among males, allowing for the emergence of large social groups.
The Supreme Court's decision increases the likelihood of states limiting or eliminating family access to medical care. Medical professionals emphasize the need for individualized assessments and patient-centered care.
A landmark review highlights how diabetes alters bone microarchitecture and increases fracture risk in people with type 2 diabetes, despite normal or elevated bone mineral density. The authors advocate for updated diagnostic tools, including a revised TBS algorithm, to more accurately reflect bone quality in individuals with central ob...
The AMA has passed a resolution calling for easier access to anti-obesity medications, which have been shown to help adults lose an average of 15-20% of their weight. Improved access could benefit millions nationwide, reducing obesity-related medical costs estimated at $173 billion annually.
The Endocrine Society supports the bipartisan legislation to ensure people living with obesity have access to effective treatments. The bill will cover anti-obesity medications and intensive behavioral therapy, addressing the chronic disease's complications like cancer, type 2 diabetes, and heart disease.
Sriram Gubbi, a physician-scientist at NIDDK, won the Endocrine Society's 2025 Endocrine Images Art Competition with his image 'The Cosmic Bubble', showcasing follicular thyroid carcinoma cells. The competition celebrates the beauty of endocrine science through microscopy.
Researchers at Kyoto University have developed a new non-invasive diagnostic method for insulinomas, which achieved 100% diagnostic accuracy in a Phase II clinical trial. The new method using positron emission tomography (PET) probe successfully detected cases difficult to diagnose through existing methods.
A large-scale study published in eClinicalMedicine found that transmasculine and gender-diverse individuals who use testosterone for an average of five years do not have an increased risk of gynecological cancer. The research, which followed 1955 participants, suggests that hormone therapy may be safe for this group.
Professor Sadaf Farooqi has been awarded the inaugural Joint ‘Endocrinology Across the Life Course Award’ for her groundbreaking research on human eating behaviour and severe childhood obesity. Her work has changed attitudes towards people with severe obesity by demonstrating its biological basis.
A new study has discovered a link between delayed puberty and an increased risk of developing type 2 diabetes in boys. According to the research, adolescent boys who experience delayed puberty are 37% more likely to develop type 2 diabetes in early adulthood, regardless of their weight or socio-economic status.
Researchers developed tiny human ovary organoids using stem cells to understand gonad development and disease. The models replicate key aspects of ovarian follicles, offering a powerful platform for studying gene function in a controlled environment.
Research found that early-life growth plays a significant role in determining final adult height, accounting for about 67% of the variation. Childhood growth also accounted for a substantial proportion of the difference in adult height.
Research reveals individuals taking oral steroids for over 3 months are 6 times more likely to be diagnosed with adrenal insufficiency than those treated with non-steroidal anti-inflammatory drugs. Long-term users of inhaled steroids also face increased risk without hospitalisations.
Research suggests that antibiotics taken during infancy, especially in the first three months, may lead to earlier onset of puberty in girls. The study, which analyzed data on over 322,000 children in South Korea, found a significant association between early antibiotic exposure and increased risk of central precocious puberty.