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Ultrasound activation in cancer immunotherapy

Researchers have developed a sonodynamic cancer immunotherapy based on semiconducting polymer nanoparticles that can be activated by ultrasound, effectively treating orthotopic pancreatic cancer in mouse models. The treatment induces immunogenic cell death and kills cancer cells without causing excessive immune responses.

SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateJun 14, 2023

Incomplete imaging for transient ischemic attack emergencies increases stroke risk

A study found that patients with transient ischemic attack (TIA) who received incomplete neurovascular imaging were at higher odds of experiencing a stroke within 90 days. The research, published in the American Journal of Roentgenology, used Medicare claims data to analyze TIA emergency department encounters.

SourceAmerican Roentgen Ray Society·JournalAmerican Journal of Roentgenology·TypeImaging analysis·DateJun 8, 2023

Ultrasound breaks new ground for forearm fractures in children

A randomized trial found that ultrasound diagnosis of forearm fractures in children resulted in similar recoveries and reduced the need for follow-up x-rays. The study suggests using bedside ultrasounds could alleviate hospital waiting times and costs, benefiting rural areas with limited access to healthcare.

SourceGriffith University·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateJun 1, 2023

UCLA Health Tip Sheet: Test results impact lung cancer screening adherence; Axillary ultrasound may be unnecessary in diagnostic screening for breast cancer; Using AI to checking endotracheal tube placement

Researchers at UCLA Health highlight the impact of test results on lung cancer screening adherence and the potential unnecessary use of axillary ultrasound in breast cancer diagnostics. Meanwhile, a new AI system helps check endotracheal tube placement with high accuracy and user satisfaction.

SourceUniversity of California - Los Angeles Health Sciences·JournalJAMA Network Open·TypeObservational study·DateJun 1, 2023

Induction of a torpor-like state with ultrasound

A multidisciplinary team led by Hong Chen successfully induced a torpor-like state in mice using ultrasound, which also worked on rats. The researchers found that stimulating the hypothalamus preoptic area with ultrasound activated neurons and induced changes in body temperature and metabolism, allowing for the preservation of energy.

SourceWashington University in St. Louis·JournalNature Metabolism·TypeExperimental study·DateMay 25, 2023

New framework for super-resolution ultrasound

Researchers at the Beckman Institute for Advanced Science and Technology have developed a new framework for super-resolution ultrasound using deep learning, reducing processing speeds from minutes to seconds. The new technology enables real-time blood flow visualization, overcoming challenges faced by conventional methods.

SourceBeckman Institute for Advanced Science and Technology·JournalIEEE Transactions on Medical Imaging·TypeImaging analysis·DateMay 25, 2023

Computer‐aided diagnosis improves breast ultrasound expertise in multicenter study

A multicenter study found that deep learning-based computer-aided diagnosis significantly improved radiologists' diagnostic performance for breast lesion classification on ultrasound. The use of CAD resulted in a 6.0% upgrade of BI-RADS category 3 assessments to category 4A, with 16.7% being malignant.

SourceAmerican Roentgen Ray Society·JournalAmerican Journal of Roentgenology·TypeImaging analysis·DateMay 24, 2023

Android-based application for photoacoustic tomography image reconstruction

A mobile application utilizing Python and a single-element ultrasound transducer has been developed for photoacoustic tomography (PAT) image reconstruction. The application successfully reconstructs high-quality images with signal-to-noise ratio values above 30 decibels, making it suitable for point-of-care diagnosis in low-resource se...

SourceSPIE--International Society for Optics and Photonics·JournalJournal of Biomedical Optics·DateApr 27, 2023

Giving pregnant women routine third trimester ultrasound scans could reduce rates of undetected breech pregnancy by 71%, enabling better care before and during labor and improved outcomes for newborns

Regular third trimester ultrasound scans can help identify undiagnosed breech pregnancies, allowing for better care before and during labor. This could lead to improved perinatal outcomes and reduced rates of undetected breech pregnancy by 71%.

SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateApr 6, 2023

Ultrasound activates anticancer agent

Researchers developed a complex that accumulates in tumour tissue and is activated by ultrasound waves, triggering the release of a toxic compound and eradicating tumours. This method could make cancer treatment less invasive and more effective for large and deep-seated tumours.

SourceRuhr-University Bochum·JournalAngewandte Chemie International Edition·TypeExperimental study·DateApr 5, 2023

New focused ultrasound effective for treating Parkinson’s, movement disorders

A new focused ultrasound treatment has been shown to improve dyskinesia and motor impairment in patients with Parkinson's disease. The study, led by UNC School of Medicine researchers, found that 69% of patients who underwent the treatment experienced a response, compared to 32% of those in the control group.

SourceUniversity of North Carolina Health Care·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateMar 14, 2023

AI-powered ultrasound imaging that detects breast cancer

A team of POSTECH researchers has developed a deep learning-based multimodal fusion network for segmentation and classification of breast cancers using B-mode and strain elastography ultrasound images. The method achieved high accuracy in distinguishing benign from malignant lesions, outperforming conventional methods.

SourcePohang University of Science & Technology (POSTECH)·JournalBioengineering & Translational Medicine·DateMar 8, 2023

The Future of Touch

A new study reveals that holographic haptic displays create diffuse and faint tactile sensations due to widespread vibration patterns in the skin. The researchers discovered a phenomenon known as constructive interference that amplifies shock waves, leading to reduced spatial precision and clarity.

SourceUniversity of California - Santa Barbara·JournalScience Advances·DateMar 1, 2023

Parkinson’s disease patients experience significant reduction in symptoms with non-surgical focused ultrasound treatment

A new study led by University of Maryland School of Medicine researchers found that focused ultrasound treatment significantly reduced tremors and improved mobility in Parkinson's patients. Nearly 70% of treated patients showed a successful response after three months, with two-thirds continuing to respond a year later.

SourceUniversity of Maryland School of Medicine·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateFeb 22, 2023

Study offers details on using electric fields to tune thermal properties of ferroelectric materials

Scientists from NC State University have discovered a way to manipulate the flow of heat through ferroelectric materials by applying different electric fields. The study, published in Advanced Materials, found that varying electric field strengths, types (AC/DC), time, and frequency can alter the thermal properties of these materials.

SourceNorth Carolina State University·JournalAdvanced Materials·TypeExperimental study·DateFeb 22, 2023

Creating 3D objects with sound

Researchers at Max Planck Institute and Heidelberg University have developed a technology to assemble matter in 3D using sound waves. They successfully printed microparticles, gel beads, and biological cells into three-dimensional shapes, paving the way for novel 3D cell culture techniques.

SourceMax-Planck-Gesellschaft·JournalScience Advances·TypeExperimental study·DateFeb 13, 2023

Focused ultrasound technique leads to release of neurodegenerative disorders biomarkers

Researchers at Washington University in St. Louis have developed a non-invasive method called sonobiopsy that uses focused ultrasound to release neurodegenerative biomarkers into the blood, facilitating diagnosis of conditions like Alzheimer’s disease. The technique has shown promising results in releasing tau proteins and another biom...

SourceWashington University in St. Louis·JournalRadiology·TypeExperimental study·DateJan 31, 2023

A research led from ITEFI-CSIC achieves inhibition of cancer cell migration in vitro after low intensity ultrasound irradiation, allowing a controlled modification of the tumor cells biodynamics without damage

A study led by CSIC demonstrates the efficiency of low-intensity ultrasound therapy in inhibiting cancer cell migration in pancreas cancer models. The researchers successfully controlled tumor cell biodynamics without causing damage.

SourceSpanish National Research Council (CSIC)·JournalFrontiers in Cell and Developmental Biology·DateJan 30, 2023

A precision arm for miniature robots

Researchers at ETH Zurich have created a device that uses ultrasound to automate laboratory analysis tasks. The device combines microfluidics and robotics, allowing for the mixing, pumping, and trapping of tiny amounts of liquid. This innovation enables the automation of previously custom-designed systems.

SourceETH Zurich·JournalNature Communications·DateJan 13, 2023