Researchers developed a non-toxic, small-molecule probe that provides real-time visualization of disease progression, overcoming limitations of MRI and PET imaging. The probe binds copper ions and detects dysregulated levels, accurately identifying Wilson's disease and other maladies.
A new AI system developed by NYU and NYU Abu Dhabi researchers achieves radiologist-level accuracy in identifying breast cancer in ultrasound images. The system helps decrease false-positive findings and requested biopsies while maintaining sensitivity.
A new study shows an artificial intelligence tool improved radiologists' ability to correctly identify breast cancer in ultrasound exams, with a 37% increase in accuracy. The tool also reduced the number of tissue samples needed to confirm suspect tumors by 27%.
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A recent study published in AJR found that gallbladder polyps can fluctuate significantly in size and number over time. The authors suggest revising guidelines to reflect this variability, with no cases of gallbladder carcinoma identified in patients who underwent cholecystectomy.
High-intensity focused ultrasound (HIFU) technology is being explored for its potential to destroy cancerous tumours while minimizing damage to healthy tissue. Researchers at the University of Waterloo have made significant progress in understanding how HIFU works on a cellular level, paving the way for future clinical trials.
Researchers at UC San Diego developed a cancer immunotherapy that pairs ultrasound with CAR T-cell therapy to destroy malignant tumors while sparing normal tissue. The therapy significantly slowed down tumor growth in mice and showed minimal on-target, off-tumor side effects.
A new ultrasonic method improves fetal weight prediction accuracy by analyzing three-dimensional limb volumes and abdominal circumferences. The algorithm outperforms traditional formulas in predicting macrosomia and birth weights.
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Scientists from Tokyo Metropolitan University have created a technology that allows objects to be lifted off reflective surfaces without physical contact using sound waves. They employed a hemispherical array of ultrasound transducers to generate a 3D acoustic field, stably trapping and lifting a small polystyrene ball.
A soft and stretchy ultrasound patch can monitor blood flow and heart function in real-time, detecting cardiovascular conditions like strokes and heart attacks. The patch is non-invasive and can penetrate deep tissue depths, providing a more comprehensive picture of internal organs.
Researchers developed a tapered fiber optoacoustic emitter (TFOE) for non-genetic photoacoustic neural stimulation at the single cell level. The technology achieves high spatial resolution and optoacoustic conversion efficiency, allowing for precise control over neuron activity patterns.
Penn State researchers have developed an imaging technique that can not only identify but also potentially treat deep vein thrombosis by breaking down blood clots. The particles used in the technique bind to activated platelets and inhibit further clot growth, disrupting the clot or inhibiting its mechanism to persist.
A prospective study found that returning to routine screening for BI-RADS 3 lesions on supplemental automated whole-breast ultrasound substantially reduces the recall rate, with no increase in adverse outcomes. The study involved 2,257 women and showed a 3.8% recall rate, 0.5% biopsy rate, and 58.3% positive biopsy rate.
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Researchers at Imperial College London have created a metal-based molecule that inhibits the build-up of amyloid-β peptides associated with Alzheimer's disease. The molecule was shown to be non-toxic to human brain-like cells and cross the blood-brain barrier in mice using focused ultrasound.
Researchers at the University of Queensland have found that low-intensity ultrasound can effectively restore cognition without crossing the blood-brain barrier in mice models. The findings provide a potential new avenue for non-invasive treatment and will help clinicians tailor medical treatments to individual disease progressions.
A robot system with a digital twin uses intra-operative ultrasound to guide cardiac surgeons, improving their view of the patient without radiation exposure. The platform can assist less experienced operators and aid in pre-planning and real-time control.
Researchers summarize the mechanism of ultrasound neuromodulation, which uses focused ultrasound to regulate neural circuits. The treatment shows promise for treating various neurological disorders, including epilepsy and depression, with potential for future developments in genetic engineering or nanotechnology.
Researchers discovered non-reciprocal propagation in polarization-maintaining optical fibers due to ultrasound interaction. This phenomenon enhances sensing measurements and signal processing beyond the fiber's boundaries, opening new possibilities for advanced sensor networks.
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A study found that using ultrasound to monitor lung congestion in hemodialysis patients with high cardiovascular risk improved patient outcomes. The technique reduced episodes of decompensated heart failure and cardiovascular events by 37% and 63%, respectively.
Researchers at Fralin Biomedical Research Institute will advance noninvasive brain and cancer treatments with the new MRI-guided focused ultrasound facility. The technology, already used to treat movement disorders and solid tumors, aims to deliver precise energy to alleviate symptoms associated with neurodegenerative disorders.
Abbreviated lung ultrasound protocols show similar diagnostic sensitivity to 28-zone studies, suggesting they can efficiently diagnose volume overload. Researchers found no mortality differences between patients with mild and moderate-to-severe pulmonary congestion.
Researchers at Aalto University developed a new audio technique that allows people to track bats in flight and localise sources of ultrasonic sound, enabling super-hearing. The device records ultrasound using microphones on a small sphere, pitch-shifts the signal, and plays it back through headphones.
Researchers investigate acoustic analysis of underlying tissue in this groundbreaking study, revealing a small but quantifiable impact of superficial tattoos on acoustic responses. The findings suggest near-vertical transitions between areas of different sound speeds cause artifacts in ultrasound images.
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The LUCA device, a low-cost near-infrared optical device combined with ultrasound, has shown potential in identifying benign or malignant thyroid nodules. Clinical tests demonstrated a 100% sensitivity and 77% specificity in classifying nodules as clear cases or those requiring further diagnosis.
A new brain stimulation technique, sonothermogenetics, has been developed by combining ultrasound and genetics to activate specific neurons in the brain.
Researchers found that widely used SRU Consensus Criteria overestimated ICA stenosis severity. New criteria propose increasing peak systolic velocity thresholds and requiring higher PSV ratios for accurate diagnosis.
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Placental bulge sign on prenatal ultrasound or MRI significantly aids diagnosis of severe placenta accreta spectrum disorder, warranting hysterectomy over conservative management. The sign's accuracy and sensitivity are notable, making it a valuable tool for maternal counseling.
Researchers at UCSF have developed a method to detect complex fetal heart defects in utero, improving detection rates from 30-50% to 95%. The technique combines routine ultrasound imaging with machine learning computer tools to mimic clinicians' tasks.
A pilot clinical trial is underway to evaluate the efficacy of ultrasound stimulation in reducing COVID-19-related inflammation. The study, called UNITE Study, will recruit 40 patients with severe symptoms and compare the treatment group's recovery time to a control group receiving standard medical care.
Researchers at George Mason University are developing a wearable adhesive ultrasound sensor for biofeedback and rehabilitation following musculoskeletal injuries. The proposed technology allows for dynamic assessment of movement and functional measures, enabling personalized treatment plans to reduce recovery times.
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Researchers created a tiny, wireless chip that uses ultrasound to monitor body processes, enabling the development of miniaturized implantable medical devices. The team achieved volumetric efficiency with their design, paving the way for chips that can be injected into the body and communicate wirelessly.
Point-of-care ultrasonography significantly improves diagnostic accuracy in patients with acute dyspnea, allowing for quicker diagnosis and treatment initiation. The technology involves mobile ultrasound devices that enable rapid scanning of multiple organs, including lungs, hearts, and leg veins.
A team of researchers has developed a delivery system for RNA-based therapy in brain tumors using ultrasound and nanoparticles. The technique allows for increased tumor cell death and reduced harmful protein production, with potential for minimal side effects.
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A team of scientists has developed a phonon probe that uses optical fibers to create high-resolution 3D images of biological cells and tissue. The device achieves lateral resolution of 2.5 μm and can measure object height with 45 nm precision, opening up new possibilities for non-destructive diagnostics.
A new ultrasound technique has been developed to detect fetal circulation problems in the placenta, allowing for earlier diagnosis and potential prevention of harm to the fetus. The study found that 16 women out of 40 tested had placentas with fetal circulation problems.
Researchers at Carnegie Mellon University have developed a new noninvasive therapy using low-intensity focused ultrasound that can target specific cell types in the brain. The technology has shown promise in treating conditions such as Parkinson's Disease, epilepsy and insomnia.
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Professor Ullsperger and his team aim to understand the neural mechanisms behind cognitive control and decision-making using new methods, including brain stimulation with focused ultrasound. The research may lead to new therapeutic possibilities for psychiatric disorders such as OCD.
A team of engineers is exploring new methods to focus ultrasound waves through the skull, offering a safer and less expensive alternative to MRI technology. The researchers are also investigating how vibrations and waves across different frequencies can be used to extract information from or focus energy on the brain.
Researchers created a low-cost ultrasound training phantom to train treatment of trigger fingers using ultrasound guidance. The 3D-printed anatomical finger model, embedded in ballistic gelatin, allows for precise insertion of a syringe needle and mimics human anatomy and echogenic appearance.
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The Infusion Nurses Society has adopted the international Aseptic Non Touch Technique (ANTT) framework as a standard in its 2021 Infusion Therapy Standards of Practice. ANTT reduces variability and improves patient safety, particularly with ultrasound-guided peripheral IV insertions.
Mathematicians and engineers at the University of Utah have developed a method to create quasiperiodic structures using ultrasound waves, which could lead to customizable materials. The researchers created a pattern similar to a Penrose tiling by arranging carbon nanoparticles in an octagonal setup.
A large multi-center study trains convolutional neural networks to classify breast lesions from ultrasound images, achieving high accuracy rates. The model's performance is compared to that of experienced ultrasonologists, showcasing the potential of AI in speeding up early cancer detection and reducing workload.
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Researchers developed a new type of minimally invasive BMI using functional ultrasound technology, which can accurately map brain activity from precise regions deep within the brain. This breakthrough allows for high-performance, less-invasive brain-machine interfaces that could benefit people with paralysis or neurological injuries.
Researchers at MIT used computer simulations to model the mechanical response of coronaviruses to ultrasound vibrations. They found that frequencies between 25-100 megahertz triggered shell and spike collapse within a millisecond.
Researchers created a quadruple fusion optical and ultrasound imaging system, integrating four modalities: ultrasound, photoacoustic, optical coherence tomography, and fluorescence imaging. The system uses a transparent ultrasound transducer to produce high-quality images without limitations.
A large multidisciplinary study led by King's College London found that MRI scanning can show malformations in great detail, including their effect on surrounding structures. The procedure is safe for pregnant women and their babies, making it a valuable tool for clinicians and parents.
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A multidisciplinary research team has built nanoscale bubbles with customizable outer shells that can travel to and penetrate inaccessible areas in the human body. The breakthrough enables clearer ultrasound images and potentially improved disease detection and targeted drug delivery.
Researchers have developed a new technique called sonolithography, which harnesses the power of sound to create precise patterns on surfaces from aerosol droplets or particles. This method has far-reaching implications for biomedicine, electronics, and other fields, offering improved speed, cost, and precision in non-contact patterning.
A new radiology research study suggests that focused ultrasound treatment may induce an immunological healing response in Alzheimer's patients, and open the blood-brain barrier. The treatment targets the hippocampus, which plays a large role in learning and memory.
Researchers identified 23 cases of axillary adenopathy after COVID-19 vaccination, with 13% being symptomatic. The study highlights the importance of considering vaccination date and laterality in assessing imaging-detected axillary adenopathy.
Researchers found that higher lung ultrasound scores correlated with increased risk of ICU admission, intubation, and death in severe COVID-19 patients. The study used a scoring protocol covering 12 lung regions to predict patient outcomes.
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Sonoporation, a technique combining ultrasound with microbubbles, creates openings in cell membranes, allowing enhanced drug or gene intracellular delivery. Recent advances using contrast agents are expanding applications to gene expression, apoptosis, differentiation, and epigenetic reprogramming.
A hybrid approach combining hardware- and computer vision-based tracking improves the accuracy of laparoscopic ultrasound imaging. By using a custom tracking mount with EM sensors and CV markers, the system can track the transducer's pose with high accuracy.
Researchers have developed targeted ultrasound techniques to treat various brain diseases such as Alzheimer's, Parkinson's, and stroke. The new methods aim to improve brain functions by activating functional neurons without significant side effects.
A new ultrasound technique called MRI-guided focused ultrasound ablation (MRgFUS) effectively treats intermediate-risk prostate cancer with minimal side effects. Treatment was successfully completed in all 44 men, with no major adverse events and 93% disease-free at the treatment site.
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Researchers report two more patients in minimally conscious states show significant improvement after receiving low-intensity focused ultrasound treatment. One patient demonstrated ability to respond to commands and communicate with family members, while another showed recognition of objects and understanding of speech.
A light-weight, wirelessly controlled brain stimulator has been developed to treat cerebral infarction using wearable wireless ultrasound devices. The device significantly improved motor functions in a rat stroke model, paving the way for non-invasive neurorehabilitation therapy.
Researchers from RUDN University and RLT propose that stimulating lymphocyte regeneration with combined biophysical radiances can help fight COVID-19. They found a correlation between bioenergetics and immune system reactions, suggesting a potential solution to the disease's progression.
Researchers found that focused ultrasound improved parkinsonian symptoms by 10 points in treated patients, with potential benefits for those with asymmetrical symptoms and limited treatment options. However, further refinements of the technology are needed to ensure reliability and safety.
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Engineers developed a new technique to eliminate particularly tough blood clots by using engineered nanodroplets and an ultrasound drill to break up the clots from the inside out. In vitro testing showed promising results, with the use of nanodroplets, ultrasound, and drug treatment reducing clot mass by 40%, plus or minus 9%.
Researchers from Lithuania's three top universities have developed a method to improve anticancer drug delivery by combining low-intensity pulsed ultrasound with microbubbles. The team found that the rate of microbubble survival time is the best indicator for determining sonoporation efficiency.