Articles tagged with Tomography
Researchers from Brookhaven National Laboratory have developed an effective way to image a single cell using multiple techniques, providing significant implications in medicine and agriculture. The team used advanced X-ray imaging technologies to capture high-resolution images of the cellular structure and chemical processes within cells.
Researchers studied the anatomy of mudskippers to understand their adaptations to life on land. They found that the fish's muscles in the pectoral fins are bigger and that some bone-connecting tendons were replaced by fascia tissue, providing stability and strength for walking.
Researchers have created a detailed 3D atlas of the African clawed frog's development, revealing key changes during metamorphosis. The atlas uses X-ray microtomography to show the transformation from tadpole to mature adult frog.
Researchers have determined the structure of molecules within an Alzheimer's disease brain for the first time using cryo-electron tomography and fluorescence microscopy. This study revealed the molecular structure of tau protein and its arrangement with amyloid plaques, providing new insights into the pathology of the disease.
A new study published in Science Advances documents the first case of Down syndrome in Neandertals, named 'Tina', and reveals that they provided extensive care for a young child with severe hearing loss. The discovery sheds light on the existence of true altruism among Neandertals.
Scientists at uOttawa have developed Fourier Quantum Process Tomography (FQPT) to validate quantum circuit performance. The technique allows for high-accuracy characterization with minimal measurements, enabling significant advancements in quantum computing.
Researchers are working to make publicly funded data collection in computed tomography widely available and understandable by diverse communities. The Non-Clinical Tomography Users Research Network aims to improve data handling across scientific disciplines and standardize data acquisition, handling, and sharing.
A groundbreaking system utilizing a flexible tactile sensor based on electrical impedance tomography (EIT) offers significant advantages in terms of flexibility and sensitivity compared to conventional methods. The system achieved high classification accuracies, with reconstructed images and measured voltage vectors.
A team of researchers used state-of-the-art imaging techniques to study lithium-ion battery cells. They identified macroscopic deformations in the copper current collector due to local accumulations of silicon during electrode manufacturing. The defects compromise cell structure and functioning when agglomerates exceed 50 microns in size.
Canadian researchers have developed a new 3D printing method called blurred tomography that can rapidly produce microlenses with commercial-level optical quality. The method uses projected light to solidify a light-sensitive resin in specific areas, allowing for rapid prototyping of optical components.
Scientists have developed a new approach to simulate the magnetization reversal of Nd-Fe-B magnets, shedding light on microstructural features hindering coercivity. The digital twins can guide the development of sustainable permanent magnets with ultimate performance.
Researchers have discovered a rare dust particle trapped in an ancient meteorite that formed from a star other than the sun. The particle contains exceptionally high levels of magnesium isotopes, which can only be explained by formation in a hydrogen-burning supernova.
The T2oFu method offers a new approach to quantitative phase and polarization-sensitive tomography, enabling high-contrast images of muscle fibers with implications for diagnosing skeletal myopathies. The technique has been successfully tested on heart tissue samples with cardiac amyloidosis, providing promising results.
Researchers have discovered distinct characteristics of the lower mantle flow field beneath the Philippine Sea Plate. They found that ancient N-S fast velocity directions exist at depths of 700-900 km and are not related to slab subduction or a mantle plume.
A new method for phase-modulated stimulated Raman scattering tomography enables rapid, label-free 3D chemical imaging of live cells and tissues. This technique improves lateral resolution and imaging depth compared to conventional methods.
The Komodo Dragon's teeth develop and replace rapidly, with up to five replacement teeth per position in its jaws. This allows it to quickly respond to prey capture or injury, making it an ideal model for studying theropod dinosaur life history and feeding strategies.
A research team led by Professor Yang Yong found that severely oxidized metallic glass nanotubes can attain an ultrahigh recoverable elastic strain of up to 14% at room temperature. The discovery implies that oxidation in low-dimension metallic glass can result in unique properties for applications in sensors, medical devices, and othe...
Research reveals that a small subset of bacterial cells produces deadly toxins while sacrificing themselves for the benefit of their comrades. The bacteria use a temperature-sensitive genetic switch to synchronize toxin production with cell enlargement, ensuring an efficient strategy for infection.
The review discusses the optical aspects of QPAT, including mathematical models for light propagation and interaction with biological tissues. The authors outline two approaches to estimating chromophore concentrations from absorbed optical energy density data, highlighting the challenges associated with practical implementation, such ...
A new decision rule has been developed to identify patients who can safely forgo a head CT scan after falling, reducing unnecessary imaging and costs. The Falls Decision Rule can be applied to all older adults who have fallen, regardless of sustaining a head injury or recalling the fall.
Scientists have developed a new method to investigate the deposition and impact of microplastics in soil, using neutron and X-ray tomography. The technique allows for the precise location of microplastic particles and analysis of changes to soil structure, shedding light on the environmental implications of microplastic pollution.
Researchers describe the use of ripretinib and repeated surgical resection in a patient with recurrent GIST harboring a KIT exon 11 mutation. The treatment led to extended clinical benefit, outperforming current reported data from ripretinib clinical trials.
Researchers at Max Planck Institute of Molecular Physiology developed an innovative imaging technique to visualize the cardiac thick filament in its native environment. The resulting high-resolution image reveals new insights into the molecular organization and function of the sarcomere, a crucial component of heart muscle contraction.
Researchers at Northwestern University and Field Museum analyzed lunar crystals to determine the Moon's age, finding it to be approximately 4.46 billion years old, 40 million years older than previous estimates. This discovery sheds light on the Moon's formation and its impact on the Earth's planetary system.
Researchers used dynamic total-body PET scans to visualize immune T cell distribution in recovering patients. The study found increased concentrations of CD8+ T cells in the bone marrow of recovering COVID patients compared to healthy controls.
A new geometric deep learning model called GFCN has been developed to detect stroke lesions in brain imaging scans. The model leverages rich geometric information to segment brain tissue and achieves higher segmentation performance than other neural network architectures.
Researchers developed a convolutional neural network to identify structures in cryo-X-Ray-microscopy data, achieving high accuracy within minutes. The AI-based analysis method enables faster evaluation of 3D X-ray data sets and has potential applications in studying cell responses to environmental influences.
Researchers at HZDR are developing a low-cost muon detector for non-destructive condition monitoring of industrial facilities. The detector aims to reduce costs and enable long-term monitoring, with potential applications in bridge inspection and nuclear waste management.
Researchers used cryo-electron tomography to study the dynein motor protein, revealing new details about how it generates force and coordinates with other proteins. This knowledge may help develop treatments for diseases related to cilia dysfunction, such as fertility issues and lung disease.
A University of Gothenburg study found that individuals who engaged in regular physical activity had smaller hemorrhages upon arrival at the hospital. Physically active patients experienced 50% less bleeding volume compared to inactive ones.
Researchers developed a virtual framework to investigate the effectiveness of optoacoustic tomography for breast cancer screening in people with darker skin. The results confirmed that tumors can be harder to locate in individuals with darker skin, highlighting the need to optimize imaging systems to mitigate racial bias.
A mobile application utilizing Python and a single-element ultrasound transducer has been developed for photoacoustic tomography (PAT) image reconstruction. The application successfully reconstructs high-quality images with signal-to-noise ratio values above 30 decibels, making it suitable for point-of-care diagnosis in low-resource se...
Researchers analyzed six sealed copper alloy animal coffins using neutron tomography, identifying bones, textiles, and lead fragments that shed light on ancient Egyptian mummification techniques and ritual purposes.
Dr. Erik K. Paulson, MD, chair of Duke University's radiology department, has been elected as the 123rd President of ARRS for a one-year term starting April 2023. He succeeds Gary J. Whitman, who served from 2022 to 2023.
Researchers observed lithium ions wandering within composite cathodes, revealing limitations in ion delivery that affect battery performance. The findings suggest a previously overlooked development bottleneck for solid-state battery development, highlighting the need to enhance ion transport within cathode composites.
Researchers developed a new reconstruction method for 3D imaging using integrated circuits, enabling non-destructive nanoscale imaging. The approach uses X-ray ptychographic tomography and deep learning to reduce acquisition time and improve fidelity, with potential applications in IC imaging, biology, and material science.
A new inverse rendering framework enables fast and efficient cloud tomography, allowing for accurate analysis of atmospheric dynamics and energy balance. The path recycling and sorting algorithm speeds up the process, overcoming computational limitations.
A cohort study of over 9,000 persons found that asymptomatic middle-aged individuals with subclinical coronary atherosclerosis are at an 8-fold increased risk for myocardial infarction. The study highlights the importance of identifying and addressing obstructive coronary artery disease in patients without known cardiovascular disease.
A team of researchers at the University of Connecticut created freeform illuminators that enable flexible illumination design and calibration using a blood-coated sensor. The newly developed technology simplifies microscopy experiments by reducing size, increasing density, and adjusting angle of illumination.
Researchers have developed a new method to encode single-cell tomograms using 3D Zernike polynomials, resulting in a data compression ratio of 22.9 and saving over 95% of space. The strategy is efficient on various experimental data types and can be applied to lab-on-a-chip systems.
A team from Chalmers University of Technology has developed a method to observe the formation of lithium microstructures in real-time using X-ray tomographic microscopy. This breakthrough aims to improve the safety and capacity of lithium metal batteries, which could replace traditional lithium-ion batteries in the future.
A new method for image reconstruction in electrical impedance tomography has been developed by Prof. DU Jiangfeng's team, enabling high-quality images without training data. This innovation provides crucial theoretical support for the application of electrical impedance tomography in various diseases.
Scientists used CT scans to analyze unopened expedition crates from the Tendaguru dinosaur site, revealing numerous dinosaur bones, including those of Dysalotosaurus lettowvorbecki. The images also provide a valuable testimony of the historic expedition and colonial context.
Researchers create advanced imaging-based method for studying mitochondria, enabling detailed mapping and measurement of structural changes. This technique has potential applications in understanding diseases such as Alzheimer’s, Parkinson’s, and cancers where mitochondrial function is disrupted.
A deep learning model distinguishes colon carcinoma from acute diverticulitis in CT images, improving diagnostic performance and reducing false-negative and false-positive findings. The model's sensitivity and specificity were significantly improved, supporting radiologists in patient care.
The Chan Zuckerberg Initiative grant will support advanced imaging training for over 2,000 scientists through a combination of hands-on events and online resources. Array tomography, an imaging technique that offers higher resolution and detailed molecular labeling, will be a key focus of the project.
Researchers developed a new epigenetic biomarker, GrimAge version 2, which leverages two DNAm-based estimators of plasma proteins to predict mortality risk. The study found that GrimAge 2 outperforms existing clinical biomarkers in predicting mortality across multiple racial/ethnic groups and associations with age-related conditions.
Researchers compared zebrafish and medaka bones, finding medaka lacks bone cells but retains water-absorbing Proteoglycans. The study suggests a new explanation for why some bones respond better to stress than others.
A team led by Abhinav Jha is developing a novel low-count quantitative single photon emission computed tomography (LC-QSPECT) method to measure the concentration of radiopharmaceutical material in tumors and vital organs. This technique aims to provide accurate measurements of absorbed dose from radiation therapy, helping plan treatmen...
A study explores the link between shark nose shape, size, and sensitivity of smell. The researchers found that more lamellae in rosettes with an elongated shape are associated with increased odor sensitivity.
A new machine learning fusion model has been developed to diagnose ovarian cancer more accurately by combining ultrasound and photoacoustic tomography imaging. The model achieved an accuracy of 90% in detecting ovarian lesions, outperforming previous methods.
A large-scale international study found that patients diagnosed with lung cancer at an early stage via CT screening have a 20-year survival rate of 80 percent. This is compared to the average five-year survival rate for all lung cancer patients, which is 18.6 percent.
Researchers observe atomic-level structural changes in bacterial ribosomes and their response to antibiotics, shedding light on mechanisms of action and potential off-target effects. The study provides new insights into the complex interactions between ribosomes and other cellular complexes.
Three pre-Columbian South American mummies found evidence of lethal trauma, with two males dying from extreme intentional violence. The study used 3D CT scans to examine the mummies and provide new insights into the rate of trauma and violent deaths in prehistoric human societies.
A study has found that pheasant meat can contain small fragments of toxic lead, which can be absorbed by the body and cause long-term harm. Researchers detected up to 10mg of tiny lead shards per pheasant, widely distributed within the bird's tissues.
Researchers use correlative tomography to analyze and verify the authenticity of shrunken heads (tsantsas) in museum collections. The study reveals new insights into these mysterious artifacts, shedding light on their origins and cultural significance.
Researchers analyzed data from trauma centers to determine if patients with seat belt injuries and negative CT scans can be safely discharged. The study found that some patients with abdominal bruising from a seat belt following a car crash may not need hospital admission.
Researchers developed an automated method to create 3D images of leaked gas clouds, enabling precise location, volume, and concentration determination. This technology can provide early leak warnings, assess risk, or determine the best way to fix leaks in large facilities with stored toxic chemicals.
Researchers used high-resolution micro-CT scans to reveal key features in Palaeospondylus fossils, placing it as an early ancestor of tetrapods. The study resolves long-standing evolutionary mysteries, including the lack of teeth and dermal bones in the fossil record.
A study by Kyoto University researchers reveals that human fetuses develop slower shoulder growth before birth, alleviating complications during delivery. This adaptation allows for a safer passage through the birth canal, reconciling the incompatibility between wide shoulders and narrow pelvis.