A new study reveals how prenatal alcohol exposure impairs key brain cells and circuits, leading to cognitive inflexibility and increased risk of compulsive alcohol use. Researchers identified a specific brain cell affected by early alcohol exposure, providing a clear target for developing more effective treatments of FASD.
A UK report highlights gender inequities in drug and alcohol services, with women often experiencing adverse childhood experiences and trauma. The study recommends improving treatment and support for women, including women-only spaces and holistic multi-agency approaches.
A large-scale cohort study found that stopping drinking even at low levels can lead to clinically meaningful reductions in blood pressure. Researchers analyzed data from over 359,000 adults and discovered that quantity of alcohol intake is the primary driver of blood pressure changes.
Researchers found that Candida albicans overgrowth increases inflammatory molecules PGE2, altering dopamine signaling and reducing desire for alcohol. Blocking PGE2 activity reverses the behavior, suggesting a potential link between gut microbiota and alcohol consumption.
A study found that participants taking GLP-1 agonists experienced delayed effects after drinking alcohol, leading to reduced intoxication. The research provides early data for larger studies testing whether these drugs can help reduce alcohol use.
A new survey conducted by UCLA found that nearly 1 in 4 transplant hepatologists in the US screen positive for unhealthy alcohol use. The study highlights the critical need for accessible physician wellness programs and reduced stigma around doctors seeking help.
Researchers found that tolcapone increases behavioral control in individuals with AUD by activating the prefrontal cortex, which is consistent with the drug's effects on dopamine levels. The study suggests a new mechanism for treating AUD beyond current medications that target the brain's reward system.
Researchers identified a promising treatment for PTSD, chronic pain, and alcohol misuse in rats. The study found that PPL-138 selectively reduced anxiety-like behavior, pain responses, and alcohol consumption in those with trauma-related anxiety.
Researchers at UC Berkeley find that chimpanzees consume about 14 grams of pure ethanol per day, equivalent to one standard American drink. This chronic exposure suggests a dietary heritage of alcohol from our common ancestor with chimpanzees.
Rates of alcohol-induced deaths in the US nearly doubled between 1999 and 2024, reaching a record high in 2021. The largest increase was among females aged 25-34, with mortality rates rising by 255%.
SourcePLOS·JournalPLOS Global Public Health·TypeObservational study·DateSep 17, 2025
A cohort study found an association between parental diseases of despair and youth suicidal events, suggesting a potential underlying factor in the increase in adolescent suicidal behavior. Improved access to care for parents with these conditions may help reduce the adolescent suicide rate.
A new longitudinal study by York University found that young adults using both substances in times of high stress and emotional distress reported more negative life consequences. The study suggests that understanding combined use can help young adults mitigate the risk and seek healthier coping mechanisms.
A UIC researcher team led by Dr. Subhash C. Pandey will investigate how long-term alcohol use affects the structure and function of brain cells, aiming to improve targeted treatments for alcohol use disorder. The grant renewal aims to fuel cutting-edge research into cellular interaction in areas key to alcohol addiction.
A comprehensive study published in the Journal of Hepatology shows that healthy eating and increased physical activity significantly lower the risk of liver-related death, even among heavy and binge drinkers. The research analyzed data from over 60,000 US adults and found that adherence to high levels of physical activity and/or diet q...
Researchers from Flinders University found a consistent increase in Obstructive Sleep Apnea (OSA) severity on weekends, driven by lifestyle choices and irregular sleep patterns. Maintaining a regular sleep routine is crucial to combat social apnea, which can lead to serious health conditions like heart disease, depression, and dementia.
A new study found that tolcapone increases activity in the prefrontal cortex during self-control tasks, associated with better behavioral control and reduced alcohol consumption. The findings suggest that medications increasing prefrontal dopamine could be a promising lead for treating alcohol use disorder.
SourceElsevier·JournalBiological Psychiatry Cognitive Neuroscience and Neuroimaging·TypeImaging analysis·DateAug 13, 2025
A new study published in JAMA found that the August 2023 Maui wildfire led to a 46% increase in statewide suicide and overdose death rates, with a 97% increase in Maui alone. The researchers suggest direct exposure and indirect effects, such as concern for loved ones, contributed to the rise in deaths.
Research from the University of Birmingham finds that party tourism creates an environment for sexual assault by normalizing extreme behavior and prioritizing economic revenue over women's safety. The study highlights how destinations silence victims to protect their reputation, reinforcing a culture of silencing survivors.
A new study found that heavy drinking among women with a high desire to avoid becoming pregnant increased their risk of undesired pregnancy by 50% compared to moderate or non-drinking levels. In contrast, cannabis use did not elevate the risk of undesired pregnancy.
A survey of over 1,600 US adults found that most know the negative impacts of smoking and drinking during pregnancy, but uncertainty exists around vaccines and weight gain recommendations. The majority are unsure about recommended vaccines for pregnant individuals, with a notable drop in knowledge since last year.
A nationwide study found that alcohol withdrawal syndrome significantly increases risks of complications and longer hospital stays after major surgery. Proactive screening and multidisciplinary care can help prevent such complications.
Research from UCLA Health Sciences found that individuals with substance use disorders are at a higher risk of unplanned hospital readmissions. Specifically, those with opioid use disorder had the highest 30-day readmission rates.
A new study found that 8.9% of workers in their 30s use substances on the job, with higher risks in food preparation/service industry and safety-sensitive occupations like construction and transportation. Comprehensive substance use policies and supportive interventions could improve safety and reduce misuse.
A new study by psychologists, linguists, and policy experts reveals that policymakers and drinkers have different ways of framing alcohol consumption. The findings suggest that policies must reflect real-life behaviours and motivations to make a meaningful difference.
This cross-sectional study reveals a substantial rise in alcohol-associated liver disease mortality, particularly among women and younger adults. The findings highlight the importance of targeted public health initiatives to address this growing health concern.
Researchers have identified a specific group of neurons in the brain responsible for suppressing binge drinking behavior. The discovery may lead to new therapeutic targets for treating alcohol dependency and related health challenges.
A recent study by UT Arlington researcher Dr. Awua found that social influences and peer pressure significantly impact substance use among young adults College students often misjudge their peers' drinking habits, leading to heavy episodic drinking and negative consequences The study suggests using protective behavioral strategies like...
A new international collaboration by the University of Exeter found that people living in greenest neighbourhoods are 13% less likely to smoke and 31% less likely to drink daily. Intentional visits to nature also have benefits, reducing smoking rates.
A study published in Contemporary Economic Policy found that adoption of vertical identification laws has not reduced teenage drinking and smoking. The analysis of 1991-2019 data from the Youth Risk Behavior Surveys revealed no statistically significant or economically important effect on these behaviors.
A new study found that collegiate recovery programs with multiple funding sources served twice as many students, providing dedicated space and relapse management support. These programs offer inclusive All Recovery meetings, which provide a welcoming space for students on different recovery journeys to connect and heal.
A new review paper suggests that social drinking is a significant contributor to alcohol use disorder, contrary to the common perception of solitary drinking. Research highlights the importance of social contexts in driving excessive alcohol consumption and related societal harms.
Research led by VCU and Rutgers University found that romantic partners' substance use habits, personality traits, and mental health status can enhance or diminish a person's genetic predisposition to binge drinking. The study suggests that couple-based interventions could be more effective when addressing environmental influences.
A systematic review of child maltreatment found that parents and caregivers with alcohol-related diagnoses were twice as likely to maltreat children. The study pooled data from twelve high-income countries and associated caregiver alcohol-related diagnoses with higher child maltreatment incidence.
A study found that hazardous drinking and daily alcohol consumption were associated with increased odds of abusive and neglectful behaviors among family caregivers of patients with dementia. The findings suggest the importance of addressing caregiving complexities and alcohol use patterns through personalized interventions.
A study suggests that perceived stress and depression are key factors in the relationship between insomnia and hazardous drinking. Insomnia can lead to heavy drinking through stress, while drinking can lead to insomnia through depression.
A history of social isolation and alcohol use may influence how males and females respond to ketamine treatment. Female rats took ketamine more than males, while prior alcohol use increased female rat ketamine intake and changed synapse structure.
Researchers found that low-dose semaglutide can reduce craving and some drinking outcomes in adults with alcohol use disorder, providing initial prospective evidence for its potential as a treatment. Larger clinical trials are needed to fully evaluate the efficacy of glucagon-like peptide 1 receptor agonists (GLP-1RAs) for this condition.
A recent study published in CANCER found that pain is associated with a greater likelihood of tobacco and cannabis use among cancer survivors. Pain also exacerbates treatment-related side effects and worsens health outcomes.
Children exposed to low to moderate levels of prenatal alcohol showed characteristic facial changes that persisted until age 6 or 8. No linear association between alcohol exposure and facial shape was found, suggesting other factors at play.
Researchers found that specific brain signals and groups of brain cells are involved in alcohol-induced insomnia, which could lead to targeted treatments for sleep loss. The study suggests that targeting specific brain cells may help people recover from alcohol use disorder.
New research reveals a 18% increase in alcohol-related deaths in Canada during the pandemic, with higher increases in 2020 and 2021. The study also found increased hospitalizations related to alcohol use, particularly among younger adults and females, suggesting potential early warning signs for future liver-related disease.
A Texas A&M University researcher found that reducing alcohol consumption aligns with a harm reduction approach, which may be a more feasible approach for high-risk college drinkers. The study surveyed 822 high-risk college students and analyzed their intention to reduce drinking using the Theory of Planned Behavior.
The AHRQ EvidenceNOW initiative reduces stigma by training primary care practices in universal screening, brief interventions, and medication-assisted therapy. Motivational interviewing techniques help clinicians address unhealthy alcohol use, promoting person-centered communication and empathetic interactions.
A new study reveals that more than half of US college students experience alcohol-related harms caused by others. The findings show that students who identified as White, cisfemale, or transgender, and those living with roommates, were at greater risk. Commonly reported harms included social harm, sleep disruptions, and emotional hurt.
Two studies suggest that psilocybin-assisted psychotherapy can improve mental health outcomes for patients with cancer and alcohol use disorder, reducing symptoms of anxiety, depression, and obsessive thoughts, while also promoting lasting personality changes.
A study of nearly 10,000 adolescents found distinct brain structural differences between those who used substances before age 15 and those who did not. These differences appeared to exist prior to any substance use, suggesting a role for brain structure in substance use risk.
Recent data from the Monitoring the Future Survey show stable and declining trends in substance use among young people, with reported use of most drugs holding steady since 2021. The survey found that adolescents most commonly reported use of alcohol, nicotine vaping, and cannabis, with levels generally declining over the past few years.
A new study suggests that alcohol's ability to increase people's pain threshold is linked to more aggressive behavior. Participants who drank alcohol were willing to inflict more pain on others, while those who consumed a placebo drink showed less aggression.
A new study by Swansea University researchers found a relationship between high alcohol consumption and long ring fingers compared to index fingers. The study used a sample of 258 university students and revealed that high prenatal testosterone relative to oestrogen is linked to high alcohol consumption in men, but not women.
A new study found that nearly 160 million Americans have been harmed by someone else's substance use, with 113 million experiencing harm from alcohol use and 46 million from other drugs. The survey also revealed significant overlap between the two groups, highlighting a major public health issue.
A new two-year grant will support research on the intersection of alcohol use and intimate partner violence among bisexual+ young adults. The study aims to identify factors contributing to alcohol-related partner violence and inform interventions tailored to this vulnerable population.
The University of Minnesota Medical School is studying how pain influences drinking behavior, particularly in individuals with chronic temporomandibular disorder (TMD) pain. Researchers aim to identify new treatment targets to help people with pain avoid alcohol-related problems.
A new study by Penn State researchers found that students who feel a sense of belonging at their university are more likely to binge drink than those who do not. The study, which analyzed data from over 4,000 university students, suggests that feeling connected to the university is associated with higher rates of substance use.
A study by researchers at UCLA found that Black, Hispanic, and American Indian adolescents are more likely to be tested for drugs and alcohol than white adolescents at pediatric trauma centers. The study suggests that clinician biases may contribute to these disparities.
A recent study by UC San Francisco and the University of Michigan found that childhood trauma can lead to increased pain, depression, and loneliness in older adults. Participants who experienced more traumatic events were more likely to experience these symptoms during their final years.
Research from Trinity College Dublin found that lower sustained attention in adolescence can predict a larger increase in cigarette and cannabis use by age 23. The study suggests using early biomarkers like sustained attention to identify vulnerable adolescents and guide targeted interventions.
The UCR medical school is developing a new curriculum to address the substance use crisis in California, which has resulted in over 6,000 opioid-related overdose deaths. The curriculum aims to promote access to treatment and health equity for substance use care, addressing biases and social determinants of health.
Researchers found that women who recalled a previous drinking episode took longer to consume vodka, suggesting lower motivation for alcohol consumption. The study also found that high-risk drinkers consumed faster than low-risk drinkers.
A study found that children who went to bed later and slept fewer hours during childhood and adolescence were more likely to try alcohol or marijuana by age 15. The researchers suggest that improving sleep in the school-age population could lead to improvements in other aspects of health, such as decision making.
Parents who struggle with alcohol use disorders can pass along symptoms of early aging to their children, affecting them well into adulthood. These accelerated aging effects include high cholesterol, heart problems, arthritis, and early onset dementia.