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Science News Archive March 2009 - Page 26


Page 26 of 26

New potential therapeutic target discovered for genetic disorder -- Barth syndrome

Researchers at NYU Langone Medical Center have discovered a new targeted intervention for Barth Syndrome, a genetic disorder causing heart and muscle failure in children. The study identified iPLA2-VIA as a potential target for therapeutic intervention, showing promise for treating the disease.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalProceedings of the National Academy of Sciences·DateMar 2, 2009

Two distinct molecular pathways can make regulatory immune cells

Researchers have identified two distinct molecular pathways that control the formation of regulatory T cells (Treg), which are vital in limiting undesirable immune responses. The study shows that if a gene called Carma1 isn't expressed normally, Treg development is impaired in the thymus, but alternative pathways can compensate.

SourcePLOS·JournalPLOS Biology·DateMar 2, 2009

Evidence appears to show how and where frontal lobe works

A Brown University study found that the frontal lobe controls decision-making along a continuum from abstract to concrete, with damage affecting higher-level functions but not lower ones. The research suggests specific areas of the frontal cortex are required for different levels of abstract decision-making.

SourceBrown University·JournalNature Neuroscience·DateMar 2, 2009

Wenchuan earthquake mudslides emit greenhouse gas

Mudslides caused by the 2008 Wenchuan earthquake may release significant amounts of greenhouse gas, including carbon dioxide and nitrous oxide, into the atmosphere. The study found that the ecosystem impacts of these mudslides could be equivalent to twice the loss of nitrogen from California ecosystems due to wildfires.

SourceAmerican Geophysical Union·JournalGeophysical Research Letters·DateMar 2, 2009

Study critiques corn-for-ethanol's carbon footprint

A Duke University-led study found that converting land to conservation reserves is a cheaper and more efficient way to reduce greenhouse gas emissions than using it for corn-based ethanol production. The researchers suggest that cellulosic ethanol production, which uses switchgrass or other species, may be a better option in the future.

SourceDuke University·JournalEcological Applications·DateMar 2, 2009

Prenatal molecular diagnosis for tuberous sclerosis complex

Researchers from Boston University School of Medicine have developed a prenatal testing method for identifying tuberous sclerosis complex (TSC) in the womb. The technique, which sequences TSC genes in amniotic fluid cells, has been shown to detect nearly 93% of mutations, offering improved treatment options for affected families.

SourceBoston University·JournalAmerican Journal of Obstetrics and Gynecology·DateMar 2, 2009

The 2 worlds of kids' morals

Research reveals marked gender and race differences in children's moral behaviors, both in the real and virtual worlds. African American children were more likely to view morally questionable virtual behaviors as acceptable when they benefited individual goals.

Airborne asthma allergens

A study found that airborne fungal groups Cladosporium and Mycelia sterilia are more common in urban areas with high vehicular traffic, contributing to the region's high asthma incidence. The research suggests a link between environmental triggers and genetic susceptibility, shedding light on the complex factors driving the epidemic.

SourceInderscience Publishers·JournalInternational Journal of Environmental Technology and Management·DateMar 2, 2009

Insulin drug study shows significant improvements in more than 52,000 diabetic patients

A major international diabetes study of over 52,000 patients from eight countries found that using biphasic BIAsp 30 insulin resulted in significant clinical improvements and greater patient satisfaction. The study showed a 53% reduction in blood glucose levels below seven percent, with major hypoglycaemia incidents falling by 94%.

SourceWiley·JournalInternational Journal of Clinical Practice·DateMar 2, 2009

Protein complex shown to play pivotal role in stem cell development in 2 Stanford studies

Scientists at Stanford University School of Medicine have identified a protein complex that plays a pivotal role in controlling the ability of embryonic stem cells to become any cell type. The finding is an important advance in harnessing the unique abilities of embryonic stem cells to treat disease and generate replacement tissue.

SourceStanford Medicine·JournalProceedings of the National Academy of Sciences·DateMar 2, 2009

Many middle-aged and older Americans not getting adequate nutrition

A new study published in the Journal of the American Dietetic Association found that many middle-aged and older Americans are not getting adequate nutrition. Supplement use was associated with meeting recommended dietary intakes for calcium, magnesium, and vitamin C, but potassium intake remained low regardless of supplement use.

SourceElsevier Health Sciences·JournalJournal of the American Dietetic Association·DateMar 1, 2009

Alcohol types and socioeconomic status are associated with Barrett's esophagus risk

A new study suggests that drinking alcohol in early adulthood may increase the risk of reflux esophagitis (RE) and Barrett's esophagus (BE), while wine consumption may reduce this risk. Higher education levels are also inversely associated with BE risk, suggesting socioeconomic status plays a role in the development of these conditions.

SourceAmerican Gastroenterological Association·JournalGASTROENTEROLOGY·DateMar 1, 2009

Vitamin A signals offer clues to treating autoimmunity

Scientists have discovered a compound called zymosan that can respond to two different receptors in dendritic cells, sending both stimulatory and calming messages. This finding could guide the development of vaccines against infectious agents and potentially boost the immune system's ability to fight chronic infections.

SourceEmory Health Sciences·JournalNature Medicine·DateMar 1, 2009

Vegetable-based drug could inhibit melanoma

Researchers have developed a potent drug against melanoma by combining compounds from green vegetables with selenium. The new compound, isoselenocyanate, targets the Akt3 protein and reduces tumor growth by 50-60%, showing potential for low-toxicity treatment.

SourcePenn State·JournalClinical Cancer Research·DateMar 1, 2009

Patients with GI bleeding admitted on the weekend have higher death rate

Research published in Clinical Gastroenterology and Hepatology found that patients with upper GI bleeding admitted on weekends had a 22% higher mortality rate and were less likely to undergo early endoscopy. Patients with peptic ulcer-related UGIB also faced increased mortality, hospital charges, and length of stay.

SourceAmerican Gastroenterological Association·JournalClinical Gastroenterology and Hepatology·DateMar 1, 2009