Researchers at Tulane National Primate Research Center are working on a new tuberculosis vaccine by modifying Mycobacterium tuberculosis to lose stress response gene SigmaH. Monkeys vaccinated with the modified strain showed better resistance to infection and protective immune responses in their lungs.
Chalmers researchers have extended the lifetime of artificial atoms by up to ten times by positioning them in front of a mirror. By controlling the distance between the atom and the mirror, they can manipulate the vacuum fluctuations that cause the atom to decay. This breakthrough could lead to more precise control over quantum systems.
Research published in the American Heart Association journal found that young women are less likely to be prescribed or fill their medication after a heart attack. Despite being eligible for the same treatment as men, only 65% of women under 55 initiated treatment on all appropriate drugs, similar to men.
Researchers found that tamoxifen enhances clearance of antibiotic-resistant bacterial pathogen MRSA and reduces mortality in mice. The study suggests that tamoxifen's immune-boosting effect could aid the immune system in cases where traditional antibiotics have failed.
Researchers from UCLA report that some dinosaurs had the ability to warm themselves by drawing heat from the sun, contradicting previous theories. The study found that these dinosaurs had higher body temperatures than modern alligators and crocodiles, suggesting they were more active.
Treatment for opioid use disorders remained low in the US during 2004-2013, with only 18.8% of individuals receiving care. Inpatient and office-based treatments increased significantly over the decade.
Advanced laser surgery and echocardiography predict fetal development and survival in complicated monochorionic twin pregnancies. Dr. Audibert presents results from 115 treated cases, exploring the usefulness of these techniques to improve outcomes.
Youths with high-functioning ASD exhibit underdeveloped and insufficiently networked social brain areas, with increased blood flow in frontal regions important for navigating social interactions. Reduced long-range connectivity between default mode network nodes may explain impairment in social responsiveness.
Researchers employed new theoretical approach to calculate glueball decay, achieving agreement with experimental data. The f0(1710) resonance is now considered a prime candidate for the long-sought-after glueball, composed of pure gluons.
A recent study by University of Colorado Boulder and U.S. Forest Service found that people who believe climate change increases wildfire risk are not more likely to take mitigation actions on their property. However, those who reject climate science are more likely to engage in risk-reducing behaviors.
A large study published in The BMJ found that women who underwent hysteroscopic sterilization using the Essure device had a significantly higher risk of reoperation following complications. The study analyzed data from over 8,000 and 44,000 women who underwent laparoscopic sterilization.
A post-hoc analysis of the ACCORD study found that higher doses of insulin were not associated with increased cardiovascular death. The study's findings provide reassurance for physicians and patients with diabetes, but underscore the need for further research to clarify the potential risks of insulin use.
Rettsyndrome.org has made a financial commitment to support Phase 2 and Phase 3 clinical trials of trofinetide in adult women and children with Rett syndrome. The organization is hopeful that these trials will be successful and lead to the first potential treatments for Rett syndrome.
A new study published in the journal Obesity found that accounting for weight history and smoking habits eliminates the mortality advantage associated with being obese. The researchers analyzed data from over 30,400 participants and found that obesity is harmful to those with cardiovascular disease, contrary to previous studies.
A study published in PLOS Medicine identified genetic ablation of P2RX7 as a promising approach to treating Duchenne muscular dystrophy, improving muscle structure, strength, and reducing cognitive impairment and bone loss. The findings suggest that P2RX7 antagonists may also reduce certain DMD phenotypes.
The number of physician-scientists is expected to decline unless steps are taken to increase recruitment and mentoring. Physician-scientists make critical contributions to medical research and discoveries.
A study found that early physical therapy for recent-onset low back pain resulted in statistically significant improvement in disability compared to usual care. However, the improvement was modest and did not achieve a clinically important difference at the individual patient level.
A recent study published in Proceedings of the National Academy of Sciences found that climbing vines are significantly reducing carbon storage in tropical forests by crowding out and killing trees. The researchers discovered that woody climbing plants, or lianas, substantially reduce forest-level carbon uptake and storage.
Recent reports from the Joseph Rowntree Foundation and Resolution Foundation reveal that poor children will see their income substantially reduced, potentially leading to more poverty. Experts warn that these changes will have serious implications for child health, with potentially 600,000 children in poverty by 2016.
A new study found that drug-resistant E. coli infections are rising in community health settings, with cases doubling from 5.28 to 10.5 incidents per 100,000 patients between 2009 and 2014.
Researchers have discovered a potential weapon against cancer by harnessing the power of a malaria vaccine. The vaccine targets a specific carbohydrate found in both placenta and cancer cells, resulting in the death of cancer cells. Testing on mice has shown promising results, with over 90% of tumors attacked successfully.
The prevalence of nonmedical use of prescription opioids decreased among adults in the US from 2003 to 2013, while the prevalence of prescription opioid use disorders and related deaths increased. The study highlights the need for coordinated efforts to address nonmedical use of prescription opioids and heroin abuse.
Firearm-related injuries result in thousands of deaths and injuries each year, with estimated economic costs of FRIs being immense. The average inpatient length of stay for an FRI was almost 7 days at a cost of $22,000, resulting in $679 million annually on inpatient care.
The University of Houston has been named to lead a national Center for Borders, Trade and Immigration Research, receiving a $3.4 million grant from the Department of Homeland Security. The center will focus on technology, policy, and education research to strengthen national security.
A study found that Listeria monocytogenes grew rapidly on unrefrigerated caramel apples with sticks, increasing 1,000-fold in just three days. Refrigeration significantly slowed growth, and bacteria were killed by hot caramel, highlighting the need for improved food safety measures.
A recent study reveals that Android root exploits are easily abused and can be repackaged in malware. The researchers found that few exploits can be detected by mobile antivirus software, making them vulnerable to attacks.
Researchers from UC Santa Barbara develop a simple new electron-beam multilayer deposition technique to create high-quality ITO intracavity contacts, yielding significant improvements in optoelectronic properties. The technique paves the way for others to enter this realm of research and provides a critical part of gallium nitride-base...
A QUT study found young drivers are more likely to drive sleepy than drunk, with 20% of fatal crashes attributed to drink driving and 15% to fatigued driving in Queensland. Young drivers are also more accepting of enforcement practices for drink driving than sleepy driving.
The study of Durrington Walls pottery and animal bones shows evidence of planned autumn and winter slaughtering, mass animal consumption, particularly pigs, and barbecue-style roasting. This suggests a well-organized community with shared understanding of food preparation and consumption.
A study by Massachusetts General Hospital reveals that relaxation response-based programs can reduce participants' use of health services in the year following participation. The program, which combines practices such as meditation and social support, resulted in a 43% average reduction in healthcare encounters.
A team of researchers at Charité - Universitätsmedizin Berlin found that peripheral macrophages can be repurposed to clean up beta-amyloid deposits in the brain. However, even with stimulation, these cells were ineffective and require further investigation into a missing stimulus.
Matthew Disney, a professor at Scripps Research Institute, has won the Tetrahedron Young Investigator Award for his exceptional creativity and dedication to organic synthesis and bioorganic and medicinal chemistry. The award recognizes his lab's work on tackling difficult problems in biomedical science.
Researchers discovered a malaria protein that binds to a common sugar molecule found on both placentas and cancer cells. A novel technology was developed to arm antibodies with high potency toxins to specifically kill cancer cells, showing promising results in clinical trials.
Scientists discovered a malaria protein that targets sugar molecules found in placentas and most cancers, leading to the development of an anti-cancer drug. The new approach halted tumour growth in mice and showed promising results in treating non-Hodgkin's lymphoma, prostate cancer, and metastatic breast cancer.
Scientists warn of self-reinforcing cycle of permafrost thaw and global warming. Experts call on world leaders to act now to reduce carbon emissions from fossil fuel combustion.
A new study from the University of Texas at Dallas found that matching levels of racial diversity between store employees and surrounding communities leads to improved sales performance. The research merged opposing views on diversity in the workplace, suggesting that both social identity theory and the information-based perspective ca...
A new research method has been developed by Virginia Tech computer scientists to identify and prevent stealthy attacks on complex computer systems. The approach uses matrix-based pattern recognition to analyze execution paths and detect anomalies with low false positive rates.
A 16-year study of over 5,000 participants found no link between sitting time and increased mortality risk. The findings contradict NHS recommendations and challenge previous research on the health risks of sitting.
A study of 1533 cancer survivors revealed poor adherence to dietary guidelines, with lower intakes of fiber, vitamins, and minerals, but higher intakes of empty calories. Diet quality improved with age and education level.
Scientists create a 'sense' DNA drug that can undo the effects of an antisense drug used to treat blood clots. The new approach reversed the antisense drug's activity and restored normal levels of prothrombin, preventing bleeding. This breakthrough demonstrates the feasibility of using oligonucleotides to target specific genes.
A study found that local government supervisors benefit from training on conceptual leadership skills every 8-9 months, but less frequent training is needed for interpersonal skills. The study suggests that investing in more frequent conceptual skill-building can be a cost-effective way to improve employee performance.
A recent study published in Nature Medicine has provided crucial insights for the development of a protective HIV vaccine. Researchers identified how changing viral swarms can drive the generation of antibodies able to neutralize diverse HIV strains worldwide.
A study found that patients with persistent Coxiella burnetii infections, which cause Q fever, are at a higher risk of developing non-Hodgkin lymphoma. The researchers discovered that these patients often have overproduction of interleukin-10, allowing the cancer cells to evade immune detection.
Researchers at VCU Massey Cancer Center found that depleting CHD4 protein makes AML cells more susceptible to chemotherapy agents, reducing DNA damage repair and tumor-forming properties.
Tropical Cyclone 03A formed on October 10 and weakened to a remnant low pressure area by October 12. NASA's Terra satellite captured visible images of the storm as it developed.
A new study by Indiana University researchers reveals that government entities are less likely to comply with certain federal environmental regulations than similar entities owned by private companies. Publicly owned facilities are more likely to violate standards and face lower consequences for non-compliance.
Oregon State University researchers developed a new methodology to consider economic, environmental and social impacts of manufacturing processes. The approach uses unit process modeling and life-cycle inventory to analyze factors such as energy consumption, water use, and occupational health and safety.
The Harry Winston Fellowships support research to prevent, treat and cure disease in children. The three new Fellows are Dr. Claire Baldauf, studying intra-uterine growth restriction, Dr. Jina Lim examining aortic valve disease, and Dr. Emily Whang investigating inflammatory bowel disease.
Favipiravir successfully treats Lassa virus infection in guinea pigs, with high-dose treatment offering complete protection. The antiviral drug outperforms ribavirin, which can cause severe disease after treatment ends.
Researchers at Georgia State University found that severe polyinhalant users had double the rate of head injuries and higher rates of mental illness diagnoses. Polyinhalant use was also associated with delinquent behavior starting younger, highlighting the need for prevention and intervention strategies.
A recent study from Johns Hopkins Bloomberg School of Public Health suggests that the percentage of people getting treatment for opioid abuse and dependence has remained stagnant, despite a significant rise in overdose deaths. The researchers found that only 20% of individuals with a drug use disorder were in treatment during this period.
A new series of studies found that powerful individuals strongly rely on internal body cues from their motor system when making judgments about preferences, objects, movements, or letter sequences. This bias affects not only artistic preferences but also practical decision-making.
African-American women are more likely to develop aggressive breast cancer subtypes and receive substandard care compared to non-Hispanic white women. Minority women also experience disparities in treatment across all breast cancer stages, with significant differences in diagnosis timing and treatment approaches.
Biologists at the University of York have found that there is no simple relationship between insect diet and diversity, with some plant-feeding groups being incredibly rich while others are not. The study suggests that other factors play a greater role in explaining diversity.
Researchers discovered a previously unknown link between young star growth and black hole feeding habits, revealing the universality of accretion physics. The study found that young stellar objects' flickering light is similar to that of black holes and white dwarfs, supporting the idea that accretion is a universal process.
A new study found that lowering systolic blood pressure to 120mmHg can reduce the risk of left ventricular hypertrophy by 39%, compared to the standard target of 140mmHg. This reduction in blood pressure was associated with a lower risk of heart failure, stroke, and sudden cardiac death.
A £3.5 million grant will fund a trial to determine whether a weekly vitamin D supplement can prevent tuberculosis (TB) in 5,400 primary schoolchildren in Cape Town. The trial aims to discover whether the supplement can reduce the risk of acquiring latent TB infection, which may develop into active TB later in life.
Research by Dr Roman Kräussl and colleagues suggests that private equity fund performance is not significantly better than traditional stock market investments. The study found that expected returns from private equity investments are similar to those of listed securities, contradicting previous assumptions.
Graphene nanoribbons are grown on germanium crystals using chemical vapor deposition, providing a straightforward way to make semiconducting nanoscale circuits. The researchers confirmed the presence of graphene nanoribbons growing on the germanium crystal faces (1,1,1), (1,1,0) and (1,0,0).
A study by Cancer Research UK and King's College London found that cancers diagnosed at a later stage have higher mortality rates, with death rates increasing by seven per cent in practices using the two-week referral route least often. Increasing GP cancer awareness could help reduce deaths.