The Large Antenna Positioning System (LAPS) has been developed by NIST to measure transmissions to and from antennas on fast-moving mobile devices, requiring coordination between communication signals and robot motion. The system will help foster the development of 5G wireless and spectrum-sharing systems.
Researchers at ETH Zurich found that ionization delays in molecules can significantly depend on the kinetic energy of both the photoelectron and the nuclei. This study extends the concept of ionization delays introduced for atomic systems, showing that variations can be as large as those with electronic kinetic energy.
Dr. Christian Marín-Muller developed a microRNA treatment for pancreatic cancer and founded Speratum CR, a biotech company with the goal of creating effective therapies. The company has successfully completed preclinical studies and is planning to initiate its first human trial.
The US government has renewed funding for UC San Diego's Center for AIDS Research, supporting continued studies of HIV/AIDS. The five-year, $15 million grant will focus on finding a cure for HIV in those already infected and preventing transmission to uninfected individuals.
A new study published in Risk Analysis: An International Journal reveals that individuals' past tornado experiences significantly impact their perception of future tornado risks. The research found that memorable past experiences shape people's fear, dread, worry, and depression, while multiple experiences influence their belief that t...
A study found that listening to music after taking anti-hypertensive medication improves heart rate variability and reduces blood pressure. The effects were observed for about an hour after medication administration, with classical music shown to activate the parasympathetic nervous system.
Researchers found that higher local summer temperatures drove peatland formation in formerly glaciated regions, not increased rainfall. Peatlands store vast quantities of carbon and are sensitive to climate change.
A substudy of the PRECISION trial found that adding aspirin to celecoxib reduced its cardiovascular safety advantage, while maintaining fewer GI problems and kidney issues compared to ibuprofen. Celecoxib remained associated with better overall outcomes in patients taking aspirin.
Norma Olvera, a UH health education professor, has received $297,385 from the USDA to train the next generation of Hispanic obesity educators. The three-year project will recruit 36 students from three Hispanic-serving institutions and provide them with career development training in community nutrition and public health.
Early life stress may affect mental health through epigenetic changes in both stress-related and sensory networks. This new hypothesis proposes that glucocorticoids prime the epigenetic machinery while neural activation coordinates programming mechanisms.
Researchers at Stanford Medicine have developed a CAR-T therapy that eradicates diffuse intrinsic pontine glioma (DIPG) tumors in mice, leaving few residual cancer cells. The treatment targets the GD2 sugar molecule on DIPG tumors and has shown promising results, but side effects such as brain swelling must be carefully managed.
A new drug treatment has shown major tumor responses in early stage lung cancer patients before surgery, resulting in fewer relapses. The study found that providing the anti-PD-1 drug nivolumab before surgery increased anti-tumor T-cells that remained after the tumor was removed.
A new Northwestern Medicine study shows that screenings for diabetes and prediabetes could be improved by expanding the screening criteria to include additional risk factors. This would lead to the identification of most cases of prediabetes and type 2 diabetes, with only 23% of patients being missed.
Scientists at Osaka University identified RELCH as a crucial protein facilitating non-vesicular transport of cholesterol within cells. This discovery may lead to better understanding and treatment of cholesterol-related disorders.
Researchers analyzed ancient tools, ornaments, and human remains to find that early Homo sapiens adapted to climate change by staying interconnected. The study found that a vast social network helped these ancestors survive a volcanic eruption 40,000 years ago and potentially inform our response to modern global warming.
Researchers found that Finsta is used to bond with friends and escape reality, contrary to popular belief. Users post inappropriate content on Finsta to make their friends laugh and archive memories together.
A new study suggests that warmer temperatures will speed up the transition from field to forest in the eastern US, leading to increased carbon sequestration. This could result in more rapidly growing forests replacing weeds and grasses, but also raises concerns about the impact of droughts on tree growth.
Researchers at UNIGE and MBI successfully place an electron in a dual state, neither free nor bound, and regulate its electronic structure. They also discover that high-intensity lasers can amplify light, enabling new possibilities for intense laser propagation in gases.
The UTSA Open Cloud Institute is supporting collaborative R&D partnerships and creating educational opportunities through a $200,000 grant program. The institute is also launching a graduate-level certificate program in cloud computing to incorporate cloud expertise into engineering, computer science, and cybersecurity degrees.
The American Academy of Sleep Medicine advises against using medical marijuana to treat sleep apnea due to unreliable delivery methods and insufficient evidence on its effectiveness and safety. Effective treatments like CPAP therapy are available from licensed medical providers.
Dr. Charles N. Serhan received the ASIP 2018 Rous-Whipple Award for his work on molecular and cellular basis of inflammation and its resolution, recognizing his discovery of endogenous anti-inflammatory mediators that activate anti-microbial defense mechanisms.
A new emphasis on preparing for conception is needed to improve health in future generations. Research suggests that parental diet and lifestyle before conception can influence the risk of future chronic disease in children.
Combination therapy of pembrolizumab and chemotherapy significantly improves overall survival and reduces progression risk in patients with non-squamous non-small cell lung cancer. The study found a 51% reduced risk of death compared to chemotherapy alone.
A Kaiser Permanente study of over 15,000 girls and their mothers found that maternal overweight and hyperglycemia are associated with earlier onset of puberty. The study suggests that the in utero environment may affect pubertal development, increasing the risk of adverse health outcomes.
The American Association of Anatomists presented its 2018 Award Recipients to recognize outstanding achievements in human anatomy education, scientific research, and leadership. The recipients included Valerie D. O'Loughlin, Kurt Albertine, Jeffrey Laitman, and Jason Organ for their contributions to the field.
BNSF Railway has been awarded the 2018 INFORMS Prize for their pioneering integration of operations research and analytics programs. The O.R. program has driven better decision-making in various aspects of the company's rail network, resulting in annual savings of over $110 million.
Scientists have developed a new method to create more sophisticated brain-like organoid models by transplanting them into rodents, enabling longer survival and increased complexity. This breakthrough could lead to better therapies for neurological disorders, as well as the potential for human cell transplantation in the brain.
A new study found that individuals with tetraplegia and sleep apnea have distinct responses to airway narrowing, leading to increased risk of sleep disruption. This knowledge can inform targeted therapies for those affected by the condition.
A new liquid biopsy-based cancer model has revealed insights into the development of chemotherapy resistance in small-cell lung cancer. The study found that intratumoral heterogeneity, or differences in gene expression between tumor cells, contributes to rapid chemotherapy resistance.
A phase I clinical trial of BLU-667, a novel precision-targeted drug, reports significant durable disease control in patients with RET-driven cancers. The study reveals an overall response rate of 37% for RET-driven cancers, with responses of 45% for non-small cell lung cancer.
Researchers found that giving patients a single dose of anti-PD-1 therapy before surgery can predict tumor response and patient outcomes. The study also revealed that immune cells active against cancer were present in patients with longer recurrence-free survival.
A deficiency of TRIF, a key innate immune adaptor, significantly shortens the survival time of ALS mice by allowing the accumulation of toxic reactive oxygens. This study reveals a new role for innate immunity in ALS pathomechanism and provides a clue to develop a therapeutic approach for protecting motor neurons.
Australia is joining the Lancet Countdown, a global health and climate change initiative. The country will track its progress on 40 indicators across five categories, including adaptation planning, mitigation actions, and public engagement.
A study published in Frontiers in Psychology found that consuming raw fruit and vegetables is associated with lower levels of mental illness symptomology and improved psychological wellbeing. The top 10 raw foods related to better mental health include carrots, bananas, apples, and dark leafy greens.
The Pancreatic Cancer Collective, funded by the Lustgarten Foundation and Stand Up To Cancer, will accelerate research for pancreatic cancer patients. The initiative aims to improve diagnosis and treatments, as well as support the next generation of pancreatic cancer investigators.
Researchers found tumors with PTEN loss are less likely to generate an immune response, suggesting PTEN levels can predict treatment outcome. The study's findings may improve personalized medicine for BRCA-deficient ovarian cancer patients.
The SU2C Multiple Myeloma Dream Team aims to revolutionize the treatment of the incurable blood cancer by detecting precursor conditions such as MGUS or SMM. The team plans to analyze blood samples from approximately 50,000 people to identify biomarkers that can predict high-risk progression.
Research suggests that taking painkillers during pregnancy could reduce the number of cells in the testes and ovaries, which give rise to sperm and eggs. This could lead to an early menopause in females and affect the fertility of future generations.
Sebelipase alfa and two investigational RNAi therapeutics, givosiran and ARO-AAT, demonstrate positive findings in treating lysosomal acid lipase deficiency and acute intermittent porphyria. Long-term tolerability and improvements in liver injury markers are observed.
Researchers used Bio-Rad's Droplet Digital PCR technology to identify potential epigenetic biomarkers for lung cancer recurrence and detect HPV cfDNA in cervical cancer patients. The studies found associations between biomarker levels and treatment outcomes, indicating the clinical utility of ddPCR technology.
The number of people receiving HCV cure is increasing with new, highly effective treatments available; simplification of treatment delivery can accelerate global scale-up. Cure leads to reductions in liver-related deaths and cancer risk, as well as improvements in comorbidities.
A single treatment of fecal microbiota transplantation produces sustained clinical and cognitive improvements in patients with liver cirrhosis and hepatic encephalopathy. The study showed significant reductions in HE episodes and hospitalizations, as well as improvements in cognitive function over 1 year.
Researchers used an experimental therapy to block fibronectin protein, reducing scarred muscle tissue and saving mouse models from heart failure. The treatment restored function in damaged heart cells and reduced fibrosis.
A study published in the International Journal of Cancer found that regularly eating red meat increases the risk of distal colon cancer in women, with those on a red meat-free diet experiencing lower rates. The research suggests that a diet free from red meat significantly reduces the risk of this type of colon cancer.
A new study found that losing one night of sleep led to an increase in beta-amyloid, a protein linked to Alzheimer's disease. The study also showed that participants with larger increases in beta-amyloid reported worse mood after sleep deprivation.
NGM282, an engineered analogue of FGF19, inhibits bile acid synthesis and decreases markers of hepatic inflammation in patients with primary sclerosing cholangitis. Significant reductions in serum levels of ALT and AST were observed in the NGM282 3 mg/day treatment group.
The study confirms that long-term OCA treatment leads to reversal or stabilization of fibrosis/cirrhosis in patients with primary biliary cholangitis (PBC) who have had an incomplete response to ursodeoxycholic acid (UDCA). The majority of patients improved or maintained their histological stage, while two patients deteriorated.
Researchers at the University of Huddersfield have found that tungsten, a favored metal in nuclear fusion reactors, becomes brittle due to radiation damage. This discovery hinders the use of tungsten as a structural material, prompting the development of new alloys that can prevent embrittlement.
A national survey by Kessler Foundation reveals that 69% of people with disabilities are striving to work, overcoming barriers through job preparation and negotiation. The study also finds that many employees report experiencing and successfully addressing obstacles such as negative attitudes and pay disparity.
A new study found that extreme cold increases mortality and morbidity risks for people with cardiovascular and respiratory diseases, while extreme heat is risky for those with renal diseases. The research aims to develop tailored public service risk communication strategies.
Professor William Lee's research uses mathematical modeling to investigate topics such as Guinness bubbles and filter coffee machines. His work has led to the development of a mathematical model for coffee brewing that can aid machine design, and he is now exploring the link between strength and flavor in espresso.
A new study reveals increased risks for Alzheimer's disease and suicidal tendencies among children and young adults living in polluted cities. Researchers detected abnormal proteins indicative of the disease as early as infancy, highlighting the need for preventative measures.
Research by the University of Exeter and the British Trust for Ornithology found that people in crowded urban areas see fewer songbirds but more nuisance birds. In contrast, green and leafy suburbs have up to three and a half times more songbirds and woodpeckers, associated with positive human wellbeing.
Researchers Gary Lewin and Norbert Hübner are investigating the molecular mechanisms underlying neurological and heart diseases. They hope to identify ion channel anchors and characterize them at the molecular level, laying the groundwork for therapies that address tactile disorders and heart failure.
Researchers at UCR have isolated three new bacterial species from wild bees that may inhibit fungi growth in pollen provisions. These Lactobacillus strains could help preserve nectar and pollen for larvae, promoting bee health.
Researchers found that over one-third of patients denying a self-inflicted gunshot wound were likely trying to kill themselves. Hospitalized patients who denied a suicide attempt were nearly 11 times more likely to be discharged without inpatient psychiatric care. Brief psychological interventions can improve treatment outcomes.
A new study has reported a good correlation between an automated image analysis system and an expert reviewer for the identification of key markers of NASH disease activity in a pre-clinical model. The study used deep-learning algorithms applied to open-source pathology software (QuPath1) to accurately identify cell histology patterns ...
Two nationwide hepatitis C elimination programs in Georgia and Iceland have reported high levels of engagement, initiation of direct-acting antiviral agents, and cure among patients chronically infected with HCV. In Georgia, over 90% of diagnosed individuals were cured, while in Iceland, the prevalence of active HCV infection among peo...
Researchers at the University of Pittsburgh have developed a novel 'Tic-tac-toe' RF coil system for high-resolution brain imaging, addressing technical difficulties associated with ultrahigh field human MRI. The technology enables better understanding of neurological diseases such as depression, Alzheimer's disease, and schizophrenia.
The Hubble Space Telescope has imaged a massive galaxy cluster, revealing its intricate structure and the presence of dark matter. The cluster is comprised of thousands of galaxies held together by gravity, with most of its mass existing in non-luminous dark matter.