Over 1,600 scientists endorse letter calling on Congress to fully fund conservation programs to stem biodiversity decline. Funding would accelerate species recovery and ensure a stable Earth.
A major population study found that genetic variants associated with educational attainment also lower the risk of cardiovascular disease. These variants have implications for a healthier lifestyle, regardless of education level.
Researchers found that neuropsychological tests have predictive value for everyday life activities in individuals with MS. However, non-cognitive variables and person-specific factors also play a crucial role in evaluating the impact of the disease on daily functioning.
Using DNA methylation patterns, researchers reconstructed the skeletal anatomy of Denisovans, identifying 56 anatomical features that differ from modern humans and/or Neanderthals. The study provides insights into human adaptation, evolutionary constraints, and disease dynamics.
A computational model using AI identifies optimal hydropower dam sites in the Amazon basin to minimize greenhouse gas emissions. The analysis found that dams built at high elevations tend to have lower emissions per unit of power output.
A study by VA Portland Health Care System and Oregon Health and Science University researchers found that early palliative care can increase survival in patients with advanced lung cancer. The study analyzed data on over 23,000 veterans and showed that palliative care provided shortly after diagnosis can lead to improved survival rates.
Researchers at Temple University Health System have identified a new target regulating mitochondria during stress, which could lead to a new approach to treating conditions such as heart failure, heart attack, stroke, and neurodegeneration. The discovery highlights the role of MCUB in mitigating calcium overload in injured heart tissue.
Researchers have reconstructed the skeletal anatomy of Denisovans using DNA methylation patterns, identifying 56 unique features. The study reveals that Denisovans had a wider skull, longer dental arch, and unique traits that separate them from modern humans and Neanderthals.
A randomized controlled study suggests that probiotic supplements can help obese children lose body weight and reduce their risk of future metabolic conditions. The findings support the potential benefits of microbiome-based treatments for tackling childhood obesity.
Researchers found that stem cells transform into immune cells to perpetuate inflammation in chronic sinusitis, preserving the potential to regenerate olfactory tissue. This discovery may lead to better treatments for anosmia, a condition where people lose their sense of smell.
The DGIST research team has developed a flexible CZTSSe thin-film solar cell with an unprecedented efficiency of 11.4%, breaking the previous record. This achievement enables mass production using eco-friendly materials, making it easier to commercialize and apply in various fields like wearables, buildings, and automobiles.
Researchers at Rice University have created a tunable, nanoscale incandescent light source by combining near-nanoscale materials that absorb heat and emit light. The system's unique configuration allows for the emission of light in specific states and wavelengths, including infrared.
Researchers outline effective engagement strategies, including youth community advisory boards and social media outreach. They also provide guidance on selecting and training recruitment staff, monitoring study progress, and addressing legal issues.
A new study reveals that many people in the US carry Native American DNA, inherited from European and African ancestors who intermarried with indigenous individuals during colonization. The analysis shows regional patterns of Native American ancestry among Spanish descendants, distinguishing between early settlers and later immigrants.
A team of Wayne State University researchers is working to better understand the physical, chemical, and biological character of fatbergs through advanced analysis. Their study aims to identify contaminants in fatbergs and inform targeted prevention and mitigation efforts.
This observational study compared major cardiovascular events among patients with diabetes and reduced kidney function treated with metformin or a sulfonylurea. The study found that metformin was associated with lower rates of cardiovascular events compared to sulfonylureas.
Researchers have successfully recorded and processed data from 43 patients with heart failure using a machine learning-based ballistocardiogram (BCG) scale. The device measures circulation pulsing to detect worsening heart failure symptoms, potentially sparing patients hospital stays.
A new study by MIT researchers suggests that solar panels with lifetimes as short as 10 years can make economic sense for grid-scale installations. The team analyzed three types of solar installations and found that the levelized cost of electricity, not just the panel's lifetime, determines economic viability.
A new unified shock sensor developed by researchers at Yokohama National University can quickly and accurately detect and dissipate shock waves. The sensor combines imaging processing with compressible flow theory to predict the behavior of shock waves, offering improved efficiency and precision in computational fluid dynamics.
A new study by University of Queensland scientists warns that acting on climate change is more cost-effective than repairing its damage. The research, published in Science, suggests that reducing greenhouse gas emissions can save trillions of dollars in long-term costs.
Research reveals that hypoxic conditions alter p53's shape, allowing it to bind with HIF and promote cancer cell survival. This discovery may lead to new therapeutic strategies for pancreatic cancer.
A new international study by Swansea University found that kindness is the top quality people look for in a long-term partner, accounting for 22-26% of their budget. The study also revealed sex differences in mate preferences, with women prioritizing good financial prospects and men favoring physical attractiveness.
UC San Diego will collaborate with Stanford University to create the Neuroelectromagnetic Data Archive and Tools Resource (NEMAR), a brain imaging data archive and tools resource. The project aims to add human neuroelectromagnetic brain imaging, including EEG and MEG, to the OpenNeuro archive.
Tropical Storm Mario has lost its rounded shape, indicating weakening, according to NASA-NOAA satellite imagery. Wind shear is affecting the storm, with powerful thunderstorms stretching high into the troposphere, suggesting heavy rainfall potential.
A new study by Anglia Ruskin University reveals significant barriers faced by LGBT+ women in the UK healthcare system, including negative responses to coming out and assumptions of heterosexuality. The research highlights the need for explicit education on issues affecting sexual minority women.
Researchers at SMART developed a new confocal reflectance interferometric microscope to study nuclear membrane mechanics in intact cells. This label-free technology has the potential to revolutionize our understanding of metastatic cancers and genetic illnesses, enabling the identification of stem cells for therapeutic applications.
Researchers have uncovered 16 genetic regions linked to diabetic kidney disease, which may help identify potential targets for prevention and treatment. The study provides insights into the pathogenesis of DKD and could lead to new therapeutic strategies.
Researchers discovered genetic regions linked to TB resistance in African buffalos, highlighting the complex interplay between host immune responses and disease spread. The study's findings suggest a trade-off between fitness and disease resistance, with potential implications for wildlife management.
Researchers found that neurons use annexin A11 to ship internal housekeeping instructions via a 'hitchhiking' system, which may lead to new treatments for ALS. Disease-causing mutations tie up deliveries at the cell's loading docks, preventing RNA delivery to neurons.
A new study by MBL and BIOS scientists found that hurricanes like Nicole significantly affect the ocean's biological pump, accelerating the transfer of carbon from surface to deeper ocean layers. This boost provides a crucial source of food for marine life in the deep ocean.
A new study reveals a significant increase in antibiotic-resistant pathogens in chickens and pigs worldwide, particularly in developing countries. The researchers identified hotspots of resistance, including China and India, where more than half of the world's pigs and chickens are raised.
A study published in Science found that acting on climate change can have a significant return on investment, avoiding damages to people, infrastructure, and ecosystems. The research suggests that rapidly reducing greenhouse gas emissions is essential to mitigate the impacts of climate change.
Researchers found that abstaining from cigarettes does not affect the motivation for food and water. In fact, smokers are more willing to spend money on cigarettes than food during abstinence.
Nidhi Lal, a clinical assistant professor of family medicine at Boston University School of Medicine, has received the Women's Health Award from the Massachusetts Medical Society. She is recognized for her work advancing women's health in Massachusetts through various initiatives.
Researchers at Uppsala University have identified a previously unknown protein, Sac2, that regulates insulin secretion from β-cells. Lowering Sac2 levels leads to reduced insulin secretion, highlighting the importance of fat composition on secretory granule function.
A study by researchers from MIT and Max Planck Institute found that people living in a remote Bolivian rainforest tend not to perceive similarities between notes played at different registers, unlike Westerners. The brain's ability to detect pitch similarity appears to be acquired through exposure to music in octave-based systems.
Researchers at LSU Health found that metformin can delay mammary gland development, enhance tumor growth and metastasis, and decrease AMPK activation. The study suggests metformin's therapeutic value in treating breast cancer in patients with low Nischarin expression levels.
Researchers found that mitochondrial fission factor is a key regulator of cancer cell survival and proliferation. The protein's interaction with VDAC1 is critical for tumor cell growth, but disrupting this complex can activate mechanisms of mitochondrial cell death.
GPM core satellite measured rainfall rates throughout Tropical Storm Tapah, revealing rates as high as 1.6 inches per hour at the storm's center. Forecasters incorporate this data into their forecasts to predict the storm's trajectory and strength.
Tropical Storm Kiko maintained its strength and shape after weakening from hurricane-force, with strong bands of thunderstorms visible in satellite imagery. The storm is forecast to slowly strengthen and potentially regain hurricane strength on Friday.
A recent study published in Science finds that investing in climate change mitigation can save more money than the costs of climate change itself. The research highlights the benefits of limiting global warming to 1.5°C and suggests that rapidly reducing greenhouse gas emissions is essential to avoid catastrophic consequences.
Researchers at Cedars-Sinai have developed a rapid method to genetically alter laboratory mice, producing personalized models of complex cancers. The technique overcomes drawbacks in current techniques and can be used to modify patient-derived cells.
The proportion of bacteria resistant to antimicrobials has increased significantly worldwide, with critical consequences for animal health and human consumers. A new map reveals high resistance rates in regions such as northeast China, northeast India, and southern Brazil, where key antibiotics have lost efficacy.
Scientists have made a breakthrough in understanding the construction of mitochondrial ribosomes, also known as mitoribosomes, which are crucial for protein synthesis. The study reveals that these structures undergo multiple assembly steps involving various proteins and machinery.
USC scientists have identified the otopetrin 1 gene as the receptor responsible for sensing sour tastes in animals. The study found that mice with a nonfunctional Otop1 gene still produce a small response to sour taste stimuli, suggesting another signaling mechanism may also contribute to sour taste perception.
A new study by University of Washington researchers found that fluoride varnish has modest anti-cavity effects in preschoolers, with a 12% decline in new cavities. The study calls for cost-effectiveness analyses to determine its value in dental services.
Researchers found that neurons in the brain form direct cell-to-cell contacts with aggressive glioblastoma cells, transmitting activation signals that drive tumor growth and invasion. Blocking this signal transmission can slow down tumor spread, offering new avenues for treatment.
Aiming to limit warming to 1.5°C can maintain Arctic summer sea ice, forests, and coral reefs, with clear benefits for human health and economies. The authors emphasize the need for immediate and transformative actions in the next decade to achieve this goal.
Researchers identified fibers that selectively increase the abundance of beneficial microbes and tracked down the bioactive components responsible for their effects. The study provides insights into how gut communities compete or cooperate with each other for dietary fiber ingredients.
A study by researchers at Virginia Commonwealth University found that individuals with psychopathic traits have greater levels of gray matter density in the ventrolateral prefrontal cortex, a region involved in self-regulatory processes. This increased density is associated with improved impulse control and reduced antisocial behavior....
A new study from the University of Warwick reveals that people with persistent back pain or headaches are twice as likely to suffer from both disorders. The researchers suggest an association between the two types of pain, pointing to a potential shared treatment for both conditions.
A research group led by Emery Berger has developed Mesh, a system that can automatically reduce memory demands in applications. By taking advantage of virtual memory hardware, Mesh effectively squeezes out memory gaps, resulting in significant reductions of up to 40% in memory usage for certain applications.
Researchers found that relapses are clinically silent, but gametocytes continue to circulate and may infect mosquitoes. The study uses nonhuman primates to assess pathogenesis and host responses during relapses.
A new study found that using ACE inhibitors to lower blood pressure is associated with a 24% reduced risk of developing type 2 diabetes. Natural genetic variations in ACE concentrations are also linked to lower T2D risk. The researchers used Mendelian randomization to infer the causal effects of ACE inhibition on T2D risk.
A new study published in Diabetes Care found that racial and ethnic minority groups were more likely to have diabetes or prediabetes at normal or below-normal body mass index (BMI), even among those of normal weight. The research highlights the importance of screening minority patients for diabetes, regardless of their BMI.
A recent animal study identified IGF1 as essential for adult tendon growth and adaptation. Researchers found that removal of the IGF1 gene prevented tendons from growing properly.
Researchers at Newcastle University found that people with Alzheimer's disease and Lewy body dementia have unique walking patterns that signal subtle differences between the two conditions. Analyzing step length variability and step time asymmetry can accurately identify 60% of all dementia subtypes.
Researchers found that RNA granules use Annexin A11 to hitch a ride on lysosomes, which are highly mobile organelles. This transportation method is crucial for RNA to reach its destination and translate into proteins, but mutations in annexin A11 have been linked to ALS.
A study published in the journal Science reveals that US and Canadian bird populations declined by 29% between 1970 and 2020, with losses across diverse groups of birds and habitats. The results show pervasive declines among common birds across all habitats, including backyard birds.
A study of nearly 1.9 million breast cancer patients found that men have lower three-year and five-year survival rates compared to women. The analysis attributed the difference to undertreatment and clinical characteristics.