Researchers found that mice lacking group-2 innate lymphoid cells in the small intestine prevented obesity after eating a high-fat diet. Conversely, reintroducing these cells led to obesity symptoms. The study suggests targeting small intestine ILC2s could be an effective obesity treatment approach.
The SULIS mission aims to understand the nature of solar eruptions and track magnetic clouds of charged gas. It will also demonstrate new technologies in space and precision alignment of small satellites flying in formation.
Researchers have discovered that a gene called Memo1 is necessary for organizing the scaffolding of brain cells, which plays a critical role in proper brain development. Mutations in this gene are linked to autism and can disrupt neural circuit formation, leading to disorganized layers and neuronal misplacement.
NASA's Terra and Aqua satellites detected Barbara as a powerful hurricane with maximum sustained winds of near 130 mph (215 kph). The storm is a category 4 hurricane on the Saffir-Simpson Hurricane Wind Scale, with hurricane-force winds extending up to 25 miles from the center.
A newly developed aerogel material can passively capture solar heat, reaching temperatures of up to 220°C in tests. This could enable lower-cost and simpler solar heat collection systems for various industrial and domestic uses.
A new study by Ohio State University finds that 81% of women who have experienced domestic violence have suffered a head injury, while 83% have been strangled. The research suggests that brain injury caused by blows to the head and oxygen deprivation are ongoing health issues for many survivors.
Researchers have successfully regenerated human retinal ganglion cells in a laboratory dish using lessons learned from rodent models. The discovery could lead to new methods of screening for drugs and genes impacted by glaucoma, potentially offering hope for vision loss patients.
A large study found that people with both physical illnesses and mental disorders experience a significant increase in frequent visits to emergency departments, compared to those with multiple physical illnesses or mental illness alone. This synergy between physical multimorbidity and mental disorders can lead to a greater impact on pu...
Researchers at IBS have successfully fabricated a single layer graphene film on large area copper foils with no adlayers, achieving adlayer-free and single crystal graphene. This breakthrough enables the creation of high-performance devices with consistent uniformity in the number of layers over large areas.
A new questionnaire has measured children's self-reported psychosocial, physical, and emotional needs in hospital settings. The top priorities identified by sick kids include feeling safe, getting enough sleep at night, being listened to, having places for parents to go for food and drinks, and family support.
Scientists create ointment to treat melanoma and Merkel carcinoma by suppressing tumor protein synthesis. The ointment's delivery system overcomes stability issues, allowing it to penetrate damaged skin cells and prevent relapse.
A recent study found that old-growth forests are less likely to experience high-severity fire than young-growth forests during wildfires. This suggests that old-growth forests could be used as biodiversity refuges to buffer the effects of climate change on fire regimes in the Pacific Northwest.
A new machine learning approach enables researchers to encode quantum mechanical laws into neural nets, simulating molecular motion billions of times faster than conventional methods. This breakthrough advances research in fields like drug development, protein simulations, and reactive chemistry.
A study published in Applied Ergonomics found that primary school-age children carrying loads up to 10% of their body weight experience minimal changes in movement, while exceeding this weight causes significant alterations. Pulling a backpack trolley with loads below 20% of body weight is recommended to avoid discomfort and injury
Researchers developed a stable cobalt(III)-nitrosyl complex, enabling controlled nitric oxide delivery to cells. This discovery has the potential to greatly impact treatment development for cardiovascular diseases, including vasodilation and enhanced neuroplasticity.
Researchers at UC San Diego are creating the world's first high-intensity twisted laser beams, also known as corkscrew light pulses. This achievement has potential applications in nuclear physics, astrophysics, and non-invasive tumor therapies.
A study on the cultural status of saltwater crocodiles in East Timor reveals a complex relationship between humans and animals. The research highlights the importance of incorporating traditional ecological knowledge into wildlife management to address severe human-crocodile conflict.
Researchers at OHSU discovered a short burst of exercise enhances brain function by increasing connections between neurons in the hippocampus. The study found that this 'gene' promotes small growths on neurons, allowing for better learning and memory.
Researchers found that people of all ages tend to overestimate the strength of others' emotions when actions are intentional, but not when actions are accidental. This 'egocentric bias' can lead to miscommunication and affect social behaviors like helping others.
A new article connects future population growth, agricultural development and infectious disease, highlighting the need for balance in agriculture to prevent disease outbreaks. Solutions proposed include improving hygiene, genetic variability, education, and predictive models.
In Russia, mentoring is now a widely accepted part of teacher training methodology, allowing young teachers to hone their skills and learn about new workplaces. Researchers conclude that this approach is becoming increasingly important due to constant socioeconomic and political change.
Scientists at EPFL have developed a new method for modifying cysteines on peptides and proteins using ethynylbenziodoxolones (EBXs), allowing for dual attachment points for new chemical groups. This enables the study of biological processes without interfering with them.
Researchers successfully demonstrated resonant absorption of terahertz radiation in commercially available graphene, enabling faster internet and a safe replacement for X-ray body scans. The high electron mobility in graphene makes it a promising material for ultrafast photodetectors.
MIT researchers have created a set of five fundamental parts that can be assembled into various functional devices, including a tiny walking motor. The new system uses 'digital materials' and offers an alternative approach to constructing robots, which could lead to the development of standardized kits for specific tasks.
Researchers developed an AI framework that detects rotational movements in clouds from satellite images, pointing to potentially threatening storm formations. The method achieved 99% accuracy and predicted 64% of severe weather events, outperforming existing detection methods.
Quantum sensors achieve extremely accurate results, surpassing conventional physics limits, enabling precision measurements of molecules and improving gravitational wave detectors. The new approach reduces measurement time by half while maintaining or doubling resolution.
Researchers identify DNA-PK as a master regulator of gene networks promoting aggressive prostate cancer behaviors. A clinical trial combining standard-of-care with a first-in-man DNA-PK inhibitor shows promising early results.
Researchers are using computer models developed by astronomers to create a rapid diagnostic test that can detect cancerous tissue without unnecessary biopsies. The technology has also shown promise in treating non-melanoma skin cancer, with simulations indicating that it could be effective in killing cancer cells.
New research from Duke University finds that reminding children of their various identities improves their problem-solving skills and flexible thinking about social groupings. This simple mindset switch can lead to better behavior in an increasingly diverse society.
Researchers from the University of Barcelona successfully synchronized two nanoscale optomechanical oscillators through mechanical coupling. The study demonstrates collective dynamics that can be controlled by acting externally on one oscillator only.
A study by Brigham and Women's Hospital found that a combination of high levels of dietary cholesterol with specific saturated fats exacerbates retinal damage in a preclinical model of diabetes. The research used an experimental rat model to examine the effects of different dietary fats on early molecular signs of inflammation and damage.
A large population-based study found that antidepressants significantly reduced mortality by 35% in patients with diabetes and depression. This significant reduction highlights the importance of addressing depression in individuals with diabetes, a condition where two to three times more people are at risk of depression.
A study by Penn State researchers found that low-density lipoprotein cholesterol levels below 70mg/dL increase the risk of hemorrhagic stroke. Participants with LDL levels between 70-99mg/dL had a similar risk, but those below 50mg/dL faced a significantly higher risk of 169%.
A whole brain imaging study found that excess grey matter in the brain can predict escalating drinking behavior in teens. Teens with more grey matter in certain regions were more likely to increase their drinking habits over time.
Mosquitoes have evolved to specialize in humans, recognizing distinct human odors through a complex blend of compounds. Researchers study the behavior, genetics, and brain structure of disease-carrying mosquitoes to understand this specialization.
Researchers from the University of Bath have conducted double-blind experiments showing that healthy mice pups can be born from sperm without acquired short RNA chains, challenging a proposed mechanism of epigenetic inheritance. The study undermines claims made by two 2018 papers that reported RNA addition was necessary for fertility.
Researchers at Tokyo University of Science discover that the anticonvulsant drug papaverine blocks the binding of high-mobility group box 1 (HMGB1) to its receptor, reducing inflammation in sepsis and cancer. The study uses a novel computer-based docking approach to find alternative uses for existing drugs.
The BioImage Archive is a large-scale resource hosting reference imaging data to facilitate global access and analysis. The archive aims to improve research quality, speed up scientific discovery, and advance knowledge in fields like human health, food security, and biodiversity.
Researchers studied clinician and older adult perspectives on communicating cancer screening cessation. Key findings include framing discussions around risks and benefits, patient empowerment, and addressing life expectancy concerns. The study aims to personalize cancer screening for elderly patients.
Rowan Martindale received a $570,000 NSF CAREER Grant to study ancient ocean ecosystems' responses to rapid global change. Her research focuses on the Early Jurassic's Moroccan High Atlas Mountains ecosystem collapse, which parallels modern climate change impacts.
Scientists at IDIBELL-ICO describe a novel mechanism of resistance to therapies that prevent blood vessel formation, which involves immune cells acting as tumor malignant elements. The study highlights the importance of targeting Sema4D and its secretion by macrophages to inhibit this mechanism.
Researchers found that gut microbes stimulate antiviral signals in non-immune lung cells to protect against the flu virus during early stages of infection. Enhanced baseline type I interferon signaling reduced flu virus replication and weight loss in mice.
Researchers found that intermittent fasting reduced pancreatic fat in mice, a key finding in the development of type 2 diabetes. The study suggests that excess weight-induced fat accumulation in the pancreas contributes to the onset of diabetes.
Researchers developed a micro-capillary injector that accelerates nanometer-scale structure fabrication using a supersonic jet of inert gas. The technique allows for rapid production of structures with high aspect ratios, suitable for applications in magnetic memory and quantum communication devices.
Scientists developed new theory capturing second sound phenomenon in quantum liquids, showing it can be faster than first sound. Theoretical approach uses squeezed-field path integral description, applicable to various phenomena at quantum-classical physics interface.
A new study from Oregon State University found that military veterans exposed to combat were more likely to exhibit signs of depression and anxiety in later life. The study suggests that combat experience has a unique impact on mental health trajectories in late life, independent of other health issues or stressful life events.
A recent study funded by the Morris Animal Foundation found nearly half of Mount Lofty Ranges koalas positive for Chlamydia DNA, while all Kangaroo Island koalas were free from the disease. The team's results suggest that Kangaroo Island may be a safeguard against further losses and even extinction due to chlamydial disease.
A team of researchers has discovered a new way to target the unique metabolism of drug-resistant parasites, using a molecule called rhodoquinone. This approach could lead to the development of new drugs that selectively kill parasites without harming humans.
A new paper argues that wildfire management through prescribed burning and restoration thinning could help save spotted owls in the West, similar to how it helped red-cockaded woodpeckers in the South. The strategy aims to reduce wildfire hazards and create more owl-friendly habitat conditions.
Astronomers have identified the atmospheric composition of a mid-size planet between Earth and Neptune for the first time using NASA's Hubble and Spitzer space telescopes. The planet, Gliese 3470 b, has a large rocky core surrounded by a deep crushing atmosphere mostly composed of hydrogen and helium.
A new study found that gastric cancer is affecting more young Hispanic people in the US, with poorer outcomes than older patients. Women under 40 were more likely to have diffuse-type tumours and stage IV disease at diagnosis, leading to a median overall survival of just 7 months.
Researchers found that people best liked the heroes they rated as most moral and least liked villains they rated as most immoral. The study, published in the Journal of Media Psychology, suggests that character morality is closely tied to how much people like them.
Since President Trump took office, FDA warning letters have fallen by a third, with significantly fewer issued during his second year. The decline in enforcement actions raises concerns among agency watchers and experts, who find the trend alarming despite the FDA's claim of ongoing regulatory efforts.
Researchers found that a specific carbohydrate attaches to a peptide hormone called atrial natriuretic peptide (ANP), regulating fluid balance and blood pressure. The study may lead to improved medications for high blood pressure.
A group of leading public health scientists calls for improved search engine and social media monitoring, as well as government support for mandatory immunization programs. They also advocate for correct dissemination of reliable vaccine information through various channels.
Researchers found that a specific esmolol-epinephrine ratio can provide cardioprotection while maintaining hemodynamic activity during myocardial ischemia and reperfusion injury. This combination therapy may be beneficial in treating patients with cardiogenic shock or cardiac arrest.
Researchers at Chalmers University of Technology have developed a unique method to study proteins trapped in glass, offering new insights into medicinal research. The method allows for the creation of a three-dimensional model of proteins in their natural environment, revealing their chemical composition and structure.
Researchers at KAUST have created a biohybrid material that performs well as an electrocatalyst, enabling the production of carbon-free fuels and green-energy applications. The material outperforms expensive metal-based OER catalysts in terms of efficiency and is environmentally friendly.
Researchers at IST Austria developed a new method to produce realistic water wave animations, now possible without sacrificing computational efficiency. The technique, which models wave-surface interactions, enables detailed scenes such as ripples forming around islands or boats passing by.
A new paper proposes a simple yet powerful model to understand why some water suppliers turn off their supply at certain times, highlighting both benefits and drawbacks of intermittent systems. The model can help guide global efforts to meet UN's Sustainable Development Goals and its Human Right to Water.